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Items: 27

1.

MDH1 and MPP7 Regulate Autophagy in Pancreatic Ductal Adenocarcinoma.

New M, Van Acker T, Sakamaki JI, Jiang M, Saunders RE, Long J, Wang VM, Behrens A, Cerveira J, Sudhakar P, Korcsmaros T, Jefferies HBJ, Ryan KM, Howell M, Tooze SA.

Cancer Res. 2019 Apr 15;79(8):1884-1898. doi: 10.1158/0008-5472.CAN-18-2553. Epub 2019 Feb 14.

2.

A genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrest.

Deiss K, Lockwood N, Howell M, Segeren HA, Saunders RE, Chakravarty P, Soliman TN, Martini S, Rocha N, Semple R, Zalmas LP, Parker PJ.

Nucleic Acids Res. 2019 Apr 8;47(6):2906-2921. doi: 10.1093/nar/gky1295.

3.

The Dynamics of TGF-β Signaling Are Dictated by Receptor Trafficking via the ESCRT Machinery.

Miller DSJ, Bloxham RD, Jiang M, Gori I, Saunders RE, Das D, Chakravarty P, Howell M, Hill CS.

Cell Rep. 2018 Nov 13;25(7):1841-1855.e5. doi: 10.1016/j.celrep.2018.10.056.

4.

Multiomic Analysis of the UV-Induced DNA Damage Response.

Boeing S, Williamson L, Encheva V, Gori I, Saunders RE, Instrell R, Aygün O, Rodriguez-Martinez M, Weems JC, Kelly GP, Conaway JW, Conaway RC, Stewart A, Howell M, Snijders AP, Svejstrup JQ.

Cell Rep. 2016 May 17;15(7):1597-1610. doi: 10.1016/j.celrep.2016.04.047. Epub 2016 May 12.

5.

High throughput cryopreservation of cells by rapid freezing of sub-μl drops using inkjet printing--cryoprinting.

Dou R, Saunders RE, Mohamet L, Ward CM, Derby B.

Lab Chip. 2015 Sep 7;15(17):3503-13. doi: 10.1039/c5lc00674k. Epub 2015 Jul 20.

PMID:
26190571
6.

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress.

Schug ZT, Peck B, Jones DT, Zhang Q, Grosskurth S, Alam IS, Goodwin LM, Smethurst E, Mason S, Blyth K, McGarry L, James D, Shanks E, Kalna G, Saunders RE, Jiang M, Howell M, Lassailly F, Thin MZ, Spencer-Dene B, Stamp G, van den Broek NJ, Mackay G, Bulusu V, Kamphorst JJ, Tardito S, Strachan D, Harris AL, Aboagye EO, Critchlow SE, Wakelam MJ, Schulze A, Gottlieb E.

Cancer Cell. 2015 Jan 12;27(1):57-71. doi: 10.1016/j.ccell.2014.12.002.

7.

Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer.

de Bruin EC, Cowell C, Warne PH, Jiang M, Saunders RE, Melnick MA, Gettinger S, Walther Z, Wurtz A, Heynen GJ, Heideman DA, Gómez-Román J, García-Castaño A, Gong Y, Ladanyi M, Varmus H, Bernards R, Smit EF, Politi K, Downward J.

Cancer Discov. 2014 May;4(5):606-19. doi: 10.1158/2159-8290.CD-13-0741. Epub 2014 Feb 17.

8.

Structural, spectral, and electrochemical properties of nickel(II), copper(II), and zinc(II) complexes containing 12-membered pyridine- and pyridol-based tetra-aza macrocycles.

Lincoln KM, Offutt ME, Hayden TD, Saunders RE, Green KN.

Inorg Chem. 2014 Feb 3;53(3):1406-16. doi: 10.1021/ic402119s. Epub 2014 Jan 17.

PMID:
24437677
9.

HTS-DB: an online resource to publish and query data from functional genomics high-throughput siRNA screening projects.

Saunders RE, Instrell R, Rispoli R, Jiang M, Howell M.

Database (Oxford). 2013 Oct 11;2013:bat072. doi: 10.1093/database/bat072. Print 2013.

10.

Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila.

Wehr MC, Holder MV, Gailite I, Saunders RE, Maile TM, Ciirdaeva E, Instrell R, Jiang M, Howell M, Rossner MJ, Tapon N.

Nat Cell Biol. 2013 Jan;15(1):61-71.

11.

Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target.

Gerlinger M, Santos CR, Spencer-Dene B, Martinez P, Endesfelder D, Burrell RA, Vetter M, Jiang M, Saunders RE, Kelly G, Dykema K, Rioux-Leclercq N, Stamp G, Patard JJ, Larkin J, Howell M, Swanton C.

J Pathol. 2012 Jun;227(2):146-56. doi: 10.1002/path.4006. Epub 2012 Apr 18. Erratum in: J Pathol. 2015 Aug;236(4):531.

12.

Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC.

McKnight NC, Jefferies HB, Alemu EA, Saunders RE, Howell M, Johansen T, Tooze SA.

EMBO J. 2012 Apr 18;31(8):1931-46. doi: 10.1038/emboj.2012.36. Epub 2012 Feb 21.

13.

Structural analysis of eight novel and 112 previously reported missense mutations in the interactive FXI mutation database reveals new insight on FXI deficiency.

Saunders RE, Shiltagh N, Gomez K, Mellars G, Cooper C, Perry DJ, Tuddenham EG, Perkins SJ.

Thromb Haemost. 2009 Aug;102(2):287-301. doi: 10.1160/TH09-01-0044.

PMID:
19652879
14.

Charge environments around phosphorylation sites in proteins.

Kitchen J, Saunders RE, Warwicker J.

BMC Struct Biol. 2008 Mar 25;8:19. doi: 10.1186/1472-6807-8-19.

15.

Association of a factor H mutation with hemolytic uremic syndrome following a diarrheal illness.

Edey MM, Mead PA, Saunders RE, Strain L, Perkins SJ, Goodship TH, Kanagasundaram NS.

Am J Kidney Dis. 2008 Mar;51(3):487-90. doi: 10.1053/j.ajkd.2007.08.030.

PMID:
18295065
17.

Delivery of human fibroblast cells by piezoelectric drop-on-demand inkjet printing.

Saunders RE, Gough JE, Derby B.

Biomaterials. 2008 Jan;29(2):193-203. Epub 2007 Oct 23.

PMID:
17936351
18.

The interactive Factor H-atypical hemolytic uremic syndrome mutation database and website: update and integration of membrane cofactor protein and Factor I mutations with structural models.

Saunders RE, Abarrategui-Garrido C, Frémeaux-Bacchi V, Goicoechea de Jorge E, Goodship TH, López Trascasa M, Noris M, Ponce Castro IM, Remuzzi G, Rodríguez de Córdoba S, Sánchez-Corral P, Skerka C, Zipfel PF, Perkins SJ.

Hum Mutat. 2007 Mar;28(3):222-34.

PMID:
17089378
19.

Deletion of Lys224 in regulatory domain 4 of Factor H reveals a novel pathomechanism for dense deposit disease (MPGN II).

Licht C, Heinen S, Józsi M, Löschmann I, Saunders RE, Perkins SJ, Waldherr R, Skerka C, Kirschfink M, Hoppe B, Zipfel PF.

Kidney Int. 2006 Jul;70(1):42-50. Epub 2006 Apr 12.

20.

A user's guide to the interactive Web database of factor H-associated hemolytic uremic syndrome.

Saunders RE, Perkins SJ.

Semin Thromb Hemost. 2006 Mar;32(2):160-8.

PMID:
16575691
21.

Factor H and atypical hemolytic uremic syndrome: mutations in the C-terminus cause structural changes and defective recognition functions.

Józsi M, Heinen S, Hartmann A, Ostrowicz CW, Hälbich S, Richter H, Kunert A, Licht C, Saunders RE, Perkins SJ, Zipfel PF, Skerka C.

J Am Soc Nephrol. 2006 Jan;17(1):170-7. Epub 2005 Dec 7.

22.
23.

Factor XI deficiency database: an interactive web database of mutations, phenotypes, and structural analysis tools.

Saunders RE, O'Connell NM, Lee CA, Perry DJ, Perkins SJ.

Hum Mutat. 2005 Sep;26(3):192-8.

PMID:
16086308
24.

Structural interpretation of 42 mutations causing factor XI deficiency using homology modeling.

O'Connell NM, Saunders RE, Lee CA, Perry DJ, Perkins SJ.

J Thromb Haemost. 2005 Jan;3(1):127-38.

25.

A tribute to Sally Childs.

Cox AR, Welchman M, Saunders RE, Koontz A, Rawson M.

Ann Dyslexia. 1988 Jan;38(1):1-7. doi: 10.1007/BF02648244. No abstract available.

PMID:
24235029
26.

Questions people ask about dyslexia.

Gomez MR, Richardson SO, Dyer JA, Darley FL, Kinsbourne M, Eisenberg L, Saunders RE, Sheridan H.

Pediatr Ann. 1979 Nov;8(11):648-59. No abstract available.

PMID:
534122
27.

Functional organelles in prokaryotes: polyhedral inclusions (carboxysomes) of Thiobacillus neapolitanus.

Shively JM, Ball F, Brown DH, Saunders RE.

Science. 1973 Nov 9;182(4112):584-6.

PMID:
4355679

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