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Items: 1 to 50 of 112

1.

Identification of bacterial pathogens and antimicrobial resistance directly from clinical urines by nanopore-based metagenomic sequencing.

Schmidt K, Mwaigwisya S, Crossman LC, Doumith M, Munroe D, Pires C, Khan AM, Woodford N, Saunders NJ, Wain J, O'Grady J, Livermore DM.

J Antimicrob Chemother. 2017 Jan;72(1):104-114. Epub 2016 Sep 25.

PMID:
27667325
2.

A Promyelocytic Leukemia Protein-Thrombospondin-2 Axis and the Risk of Relapse in Neuroblastoma.

Dvorkina M, Nieddu V, Chakelam S, Pezzolo A, Cantilena S, Leite AP, Chayka O, Regad T, Pistorio A, Sementa AR, Virasami A, Barton J, Montano X, Lechertier T, Brindle N, Morgenstern D, Lebras M, Burns AJ, Saunders NJ, Hodivala-Dilke K, Bagella L, De The H, Anderson J, Sebire N, Pistoia V, Sala A, Salomoni P.

Clin Cancer Res. 2016 Jul 1;22(13):3398-409. doi: 10.1158/1078-0432.CCR-15-2081. Epub 2016 Apr 13. Erratum in: Clin Cancer Res. 2017 Feb 1;23 (3):870.

3.

Neisseria meningitidis Lacking the Major Porins PorA and PorB Is Viable and Modulates Apoptosis and the Oxidative Burst of Neutrophils.

Peak IR, Chen A, Jen FE, Jennings C, Schulz BL, Saunders NJ, Khan A, Seifert HS, Jennings MP.

J Proteome Res. 2016 Aug 5;15(8):2356-65. doi: 10.1021/acs.jproteome.5b00938. Epub 2016 Jul 21.

4.

The Consequences of Replicating in the Wrong Orientation: Bacterial Chromosome Duplication without an Active Replication Origin.

Dimude JU, Stockum A, Midgley-Smith SL, Upton AL, Foster HA, Khan A, Saunders NJ, Retkute R, Rudolph CJ.

MBio. 2015 Nov 3;6(6):e01294-15. doi: 10.1128/mBio.01294-15.

5.

EXACT2: the semantics of biomedical protocols.

Soldatova LN, Nadis D, King RD, Basu PS, Haddi E, Baumlé V, Saunders NJ, Marwan W, Rudkin BB.

BMC Bioinformatics. 2014;15 Suppl 14:S5. doi: 10.1186/1471-2105-15-S14-S5. Epub 2014 Nov 27.

6.

The human myometrium differentially expresses mTOR signalling components before and during pregnancy: evidence for regulation by progesterone.

Foster HA, Davies J, Pink RC, Turkcigdem S, Goumenou A, Carter DR, Saunders NJ, Thomas P, Karteris E.

J Steroid Biochem Mol Biol. 2014 Jan;139:166-72. doi: 10.1016/j.jsbmb.2013.02.017. Epub 2013 Mar 26.

7.

A role for BELLRINGER in cell wall development is supported by loss-of-function phenotypes.

Etchells JP, Moore L, Jiang WZ, Prescott H, Capper R, Saunders NJ, Bhatt AM, Dickinson HG.

BMC Plant Biol. 2012 Nov 13;12:212. doi: 10.1186/1471-2229-12-212.

8.

Primary cutaneous anaplastic large cell lymphoma shows a distinct miRNA expression profile and reveals differences from tumor-stage mycosis fungoides.

Benner MF, Ballabio E, van Kester MS, Saunders NJ, Vermeer MH, Willemze R, Lawrie CH, Tensen CP.

Exp Dermatol. 2012 Aug;21(8):632-4. doi: 10.1111/j.1600-0625.2012.01548.x.

PMID:
22776000
9.

Structure of the regulatory domain of the LysR family regulator NMB2055 (MetR-like protein) from Neisseria meningitidis.

Sainsbury S, Ren J, Saunders NJ, Stuart DI, Owens RJ.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jul 1;68(Pt 7):730-7. doi: 10.1107/S1744309112010603. Epub 2012 Jun 22.

10.

ERF5 and ERF6 play redundant roles as positive regulators of JA/Et-mediated defense against Botrytis cinerea in Arabidopsis.

Moffat CS, Ingle RA, Wathugala DL, Saunders NJ, Knight H, Knight MR.

PLoS One. 2012;7(4):e35995. doi: 10.1371/journal.pone.0035995. Epub 2012 Apr 26.

11.

Transcriptomic analysis reveals calcium regulation of specific promoter motifs in Arabidopsis.

Whalley HJ, Sargeant AW, Steele JF, Lacoere T, Lamb R, Saunders NJ, Knight H, Knight MR.

Plant Cell. 2011 Nov;23(11):4079-95. doi: 10.1105/tpc.111.090480. Epub 2011 Nov 15.

12.

The use of the pan-Neisseria microarray and experimental design for transcriptomics studies of Neisseria.

Saunders NJ, Davies JK.

Methods Mol Biol. 2012;799:295-317. doi: 10.1007/978-1-61779-346-2_18.

PMID:
21993653
13.

Genome sequence of Rhodobacter sphaeroides Strain WS8N.

Porter SL, Wilkinson DA, Byles ED, Wadhams GH, Taylor S, Saunders NJ, Armitage JP.

J Bacteriol. 2011 Aug;193(15):4027-8. doi: 10.1128/JB.05257-11. Epub 2011 May 27.

14.

MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival.

Chi J, Ballabio E, Chen XH, Kušec R, Taylor S, Hay D, Tramonti D, Saunders NJ, Littlewood T, Pezzella F, Boultwood J, Wainscoat JS, Hatton CS, Lawrie CH.

Biol Direct. 2011 May 18;6:23. doi: 10.1186/1745-6150-6-23.

15.

miRNA expression profiling of mycosis fungoides.

van Kester MS, Ballabio E, Benner MF, Chen XH, Saunders NJ, van der Fits L, van Doorn R, Vermeer MH, Willemze R, Tensen CP, Lawrie CH.

Mol Oncol. 2011 Jun;5(3):273-80. doi: 10.1016/j.molonc.2011.02.003. Epub 2011 Feb 24.

16.

Deep resequencing of serial sputum isolates of Mycobacterium tuberculosis during therapeutic failure due to poor compliance reveals stepwise mutation of key resistance genes on an otherwise stable genetic background.

Saunders NJ, Trivedi UH, Thomson ML, Doig C, Laurenson IF, Blaxter ML.

J Infect. 2011 Mar;62(3):212-7. doi: 10.1016/j.jinf.2011.01.003. Epub 2011 Jan 13.

PMID:
21237201
17.

The structure of a reduced form of OxyR from Neisseria meningitidis.

Sainsbury S, Ren J, Nettleship JE, Saunders NJ, Stuart DI, Owens RJ.

BMC Struct Biol. 2010 May 17;10:10. doi: 10.1186/1472-6807-10-10.

18.

An oncogenic role of eIF3e/INT6 in human breast cancer.

Grzmil M, Rzymski T, Milani M, Harris AL, Capper RG, Saunders NJ, Salhan A, Ragoussis J, Norbury CJ.

Oncogene. 2010 Jul 15;29(28):4080-9. doi: 10.1038/onc.2010.152. Epub 2010 May 10.

PMID:
20453879
19.

MicroRNA expression in Sezary syndrome: identification, function, and diagnostic potential.

Ballabio E, Mitchell T, van Kester MS, Taylor S, Dunlop HM, Chi J, Tosi I, Vermeer MH, Tramonti D, Saunders NJ, Boultwood J, Wainscoat JS, Pezzella F, Whittaker SJ, Tensen CP, Hatton CS, Lawrie CH.

Blood. 2010 Aug 19;116(7):1105-13. doi: 10.1182/blood-2009-12-256719. Epub 2010 May 6.

20.

Tolerogenicity is not an absolute property of a dendritic cell.

Farquhar CA, Paterson AM, Cobbold SP, Garcia Rueda H, Fairchild PJ, Yates SF, Adams E, Saunders NJ, Waldmann H, Nolan KF.

Eur J Immunol. 2010 Jun;40(6):1728-37. doi: 10.1002/eji.200939974.

21.

The crystal structure of NGO0477 from Neisseria gonorrhoeae reveals a novel protein fold incorporating a helix-turn-helix motif.

Ren J, Sainsbury S, Nettleship JE, Saunders NJ, Owens RJ.

Proteins. 2010 May 15;78(7):1798-802. doi: 10.1002/prot.22698. No abstract available.

PMID:
20196080
22.

The nuclear envelope can control gene expression and cell cycle progression via miRNA regulation.

Malhas A, Saunders NJ, Vaux DJ.

Cell Cycle. 2010 Feb 1;9(3):531-9.

PMID:
20081371
23.

MS4A4B is a GITR-associated membrane adapter, expressed by regulatory T cells, which modulates T cell activation.

Howie D, Nolan KF, Daley S, Butterfield E, Adams E, Garcia-Rueda H, Thompson C, Saunders NJ, Cobbold SP, Tone Y, Tone M, Waldmann H.

J Immunol. 2009 Oct 1;183(7):4197-204. doi: 10.4049/jimmunol.0901070. Epub 2009 Sep 14.

24.

The structure of CrgA from Neisseria meningitidis reveals a new octameric assembly state for LysR transcriptional regulators.

Sainsbury S, Lane LA, Ren J, Gilbert RJ, Saunders NJ, Robinson CV, Stuart DI, Owens RJ.

Nucleic Acids Res. 2009 Aug;37(14):4545-58. doi: 10.1093/nar/gkp445. Epub 2009 May 27.

25.

Two-step assembly dynamics of the Bacillus subtilis divisome.

Gamba P, Veening JW, Saunders NJ, Hamoen LW, Daniel RA.

J Bacteriol. 2009 Jul;191(13):4186-94. doi: 10.1128/JB.01758-08. Epub 2009 May 8.

26.

Expression of microRNAs in diffuse large B cell lymphoma is associated with immunophenotype, survival and transformation from follicular lymphoma.

Lawrie CH, Chi J, Taylor S, Tramonti D, Ballabio E, Palazzo S, Saunders NJ, Pezzella F, Boultwood J, Wainscoat JS, Hatton CS.

J Cell Mol Med. 2009 Jul;13(7):1248-60. doi: 10.1111/j.1582-4934.2008.00628.x. Epub 2008 Dec 24.

27.

GLK transcription factors coordinate expression of the photosynthetic apparatus in Arabidopsis.

Waters MT, Wang P, Korkaric M, Capper RG, Saunders NJ, Langdale JA.

Plant Cell. 2009 Apr;21(4):1109-28. doi: 10.1105/tpc.108.065250. Epub 2009 Apr 17.

28.

Host iron binding proteins acting as niche indicators for Neisseria meningitidis.

Jordan PW, Saunders NJ.

PLoS One. 2009;4(4):e5198. doi: 10.1371/journal.pone.0005198. Epub 2009 Apr 8.

29.

Differential expression of microRNAs in Marek's disease virus-transformed T-lymphoma cell lines.

Yao Y, Zhao Y, Smith LP, Lawrie CH, Saunders NJ, Watson M, Nair V.

J Gen Virol. 2009 Jul;90(Pt 7):1551-9. doi: 10.1099/vir.0.009902-0. Epub 2009 Mar 18.

PMID:
19297609
30.

The structure of NMB1585, a MarR-family regulator from Neisseria meningitidis.

Nichols CE, Sainsbury S, Ren J, Walter TS, Verma A, Stammers DK, Saunders NJ, Owens RJ.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Mar 1;65(Pt 3):204-9. doi: 10.1107/S174430910900414X. Epub 2009 Feb 26.

31.

Crystallization and preliminary X-ray analysis of CrgA, a LysR-type transcriptional regulator from pathogenic Neisseria meningitidis MC58.

Sainsbury S, Ren J, Saunders NJ, Stuart DI, Owens RJ.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Sep 1;64(Pt 9):797-801. doi: 10.1107/S1744309108024068. Epub 2008 Aug 9.

32.

Structure of the cold-shock domain protein from Neisseria meningitidis reveals a strand-exchanged dimer.

Ren J, Nettleship JE, Sainsbury S, Saunders NJ, Owens RJ.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Apr 1;64(Pt 4):247-51. doi: 10.1107/S1744309108005411. Epub 2008 Mar 21.

33.

On the origin of the treponematoses: a phylogenetic approach.

Harper KN, Ocampo PS, Steiner BM, George RW, Silverman MS, Bolotin S, Pillay A, Saunders NJ, Armelagos GJ.

PLoS Negl Trop Dis. 2008 Jan 15;2(1):e148. doi: 10.1371/journal.pntd.0000148.

34.

MicroRNA expression in lymphocyte development and malignancy.

Lawrie CH, Saunders NJ, Soneji S, Palazzo S, Dunlop HM, Cooper CD, Brown PJ, Troussard X, Mossafa H, Enver T, Pezzella F, Boultwood J, Wainscoat JS, Hatton CS.

Leukemia. 2008 Jul;22(7):1440-6. doi: 10.1038/sj.leu.2405083. Epub 2008 Jan 10. No abstract available.

PMID:
18185523
35.

Sequence-based analysis of pQBR103; a representative of a unique, transfer-proficient mega plasmid resident in the microbial community of sugar beet.

Tett A, Spiers AJ, Crossman LC, Ager D, Ciric L, Dow JM, Fry JC, Harris D, Lilley A, Oliver A, Parkhill J, Quail MA, Rainey PB, Saunders NJ, Seeger K, Snyder LA, Squares R, Thomas CM, Turner SL, Zhang XX, Field D, Bailey MJ.

ISME J. 2007 Aug;1(4):331-40. Epub 2007 Jul 5.

36.

The repertoire of minimal mobile elements in the Neisseria species and evidence that these are involved in horizontal gene transfer in other bacteria.

Snyder LA, McGowan S, Rogers M, Duro E, O'Farrell E, Saunders NJ.

Mol Biol Evol. 2007 Dec;24(12):2802-15. Epub 2007 Oct 5.

PMID:
17921485
37.

Species status of Neisseria gonorrhoeae: evolutionary and epidemiological inferences from multilocus sequence typing.

Bennett JS, Jolley KA, Sparling PF, Saunders NJ, Hart CA, Feavers IM, Maiden MC.

BMC Biol. 2007 Sep 7;5:35.

38.

Induction of regulatory T cells and dominant tolerance by dendritic cells incapable of full activation.

Yates SF, Paterson AM, Nolan KF, Cobbold SP, Saunders NJ, Waldmann H, Fairchild PJ.

J Immunol. 2007 Jul 15;179(2):967-76.

39.

The structure and transcriptional analysis of a global regulator from Neisseria meningitidis.

Ren J, Sainsbury S, Combs SE, Capper RG, Jordan PW, Berrow NS, Stammers DK, Saunders NJ, Owens RJ.

J Biol Chem. 2007 May 11;282(19):14655-64. Epub 2007 Mar 20.

40.

Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression.

Malhas A, Lee CF, Sanders R, Saunders NJ, Vaux DJ.

J Cell Biol. 2007 Feb 26;176(5):593-603. Epub 2007 Feb 20.

41.

Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18.

Bentley SD, Vernikos GS, Snyder LA, Churcher C, Arrowsmith C, Chillingworth T, Cronin A, Davis PH, Holroyd NE, Jagels K, Maddison M, Moule S, Rabbinowitsch E, Sharp S, Unwin L, Whitehead S, Quail MA, Achtman M, Barrell B, Saunders NJ, Parkhill J.

PLoS Genet. 2007 Feb 16;3(2):e23. Epub 2006 Dec 21.

42.

The small FNR regulon of Neisseria gonorrhoeae: comparison with the larger Escherichia coli FNR regulon and interaction with the NarQ-NarP regulon.

Whitehead RN, Overton TW, Snyder LA, McGowan SJ, Smith H, Cole JA, Saunders NJ.

BMC Genomics. 2007 Jan 29;8:35.

43.
44.

Coordinated regulation of the Neisseria gonorrhoeae-truncated denitrification pathway by the nitric oxide-sensitive repressor, NsrR, and nitrite-insensitive NarQ-NarP.

Overton TW, Whitehead R, Li Y, Snyder LA, Saunders NJ, Smith H, Cole JA.

J Biol Chem. 2006 Nov 3;281(44):33115-26. Epub 2006 Sep 5.

45.

Comparison of the RpoH-dependent regulon and general stress response in Neisseria gonorrhoeae.

Gunesekere IC, Kahler CM, Powell DR, Snyder LA, Saunders NJ, Rood JI, Davies JK.

J Bacteriol. 2006 Jul;188(13):4769-76.

46.

Structure of the PII signal transduction protein of Neisseria meningitidis at 1.85 A resolution.

Nichols CE, Sainsbury S, Berrow NS, Alderton D, Saunders NJ, Stammers DK, Owens RJ.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jun 1;62(Pt 6):494-7. Epub 2006 May 31.

48.

Ecf, an alternative sigma factor from Neisseria gonorrhoeae, controls expression of msrAB, which encodes methionine sulfoxide reductase.

Gunesekere IC, Kahler CM, Ryan CS, Snyder LA, Saunders NJ, Rood JI, Davies JK.

J Bacteriol. 2006 May;188(10):3463-9.

49.

Complete and variant forms of the 'gonococcal genetic island' in Neisseria meningitidis.

Snyder LA, Jarvis SA, Saunders NJ.

Microbiology. 2005 Dec;151(Pt 12):4005-13.

PMID:
16339945
50.

Crystal structure of nitrogen regulatory protein IIANtr from Neisseria meningitidis.

Ren J, Sainsbury S, Berrow NS, Alderton D, Nettleship JE, Stammers DK, Saunders NJ, Owens RJ.

BMC Struct Biol. 2005 Aug 10;5:13.

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