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Items: 1 to 50 of 1153

1.

HIV-Specific T Cells Can Be Generated against Non-escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform.

Patel S, Hanajiri R, Grant M, Saunders D, Van Pelt S, Keller M, Hanley PJ, Simon G, Nixon DF, Hardy D, Jones RB, Bollard CM.

Mol Ther Methods Clin Dev. 2019 Oct 11;16:11-20. doi: 10.1016/j.omtm.2019.10.001. eCollection 2020 Mar 13.

PMID:
31720305
2.

PEGylated reduced-graphene oxide hybridized with Fe3O4 nanoparticles for cancer photothermal-immunotherapy.

Wang L, Wang M, Zhou B, Zhou F, Murray C, Towner RA, Smith N, Saunders D, Xie G, Chen WR.

J Mater Chem B. 2019 Nov 11. doi: 10.1039/c9tb00630c. [Epub ahead of print]

PMID:
31710067
3.

The influence of carrying an anterior load on attention demand and obstacle clearance before, during, and after obstacle crossing.

Jehu DA, Saunders D, Richer N, Paquet N, Lajoie Y.

Exp Brain Res. 2019 Nov 6. doi: 10.1007/s00221-019-05673-1. [Epub ahead of print]

PMID:
31690972
4.

Atovaquone-Proguanil in Combination With Artesunate to Treat Multidrug-Resistant P. falciparum Malaria in Cambodia: An Open-Label Randomized Trial.

Wojnarski M, Lon C, Vanachayangkul P, Gosi P, Sok S, Rachmat A, Harrison D, Berjohn CM, Spring M, Chaoratanakawee S, Ittiverakul M, Buathong N, Chann S, Wongarunkochakorn S, Waltmann A, Kuntawunginn W, Fukuda MM, Burkly H, Heang V, Heng TK, Kong N, Boonchan T, Chum B, Smith P, Vaughn A, Prom S, Lin J, Lek D, Saunders D.

Open Forum Infect Dis. 2019 Sep 4;6(9):ofz314. doi: 10.1093/ofid/ofz314. eCollection 2019 Sep.

PMID:
31660398
5.

Association of decreased levels of lipopolysaccharide-binding protein with OKN-007-induced regression of tumor growth in an F98 rat glioma model.

Smith N, Saunders D, Jensen RL, Towner RA.

J Neurosurg. 2019 Oct 18:1-9. doi: 10.3171/2019.7.JNS182435. [Epub ahead of print]

PMID:
31628293
6.

Phase IIb, Randomized, Double-Blind Trial of GC4419 Versus Placebo to Reduce Severe Oral Mucositis Due to Concurrent Radiotherapy and Cisplatin For Head and Neck Cancer.

Anderson CM, Lee CM, Saunders DP, Curtis A, Dunlap N, Nangia C, Lee AS, Gordon SM, Kovoor P, Arevalo-Araujo R, Bar-Ad V, Peddada A, Colvett K, Miller D, Jain AK, Wheeler J, Blakaj D, Bonomi M, Agarwala SS, Garg M, Worden F, Holmlund J, Brill JM, Downs M, Sonis ST, Katz S, Buatti JM.

J Clin Oncol. 2019 Oct 16:JCO1901507. doi: 10.1200/JCO.19.01507. [Epub ahead of print]

PMID:
31618127
7.

In-Plane Thorium(IV), Uranium(IV), and Neptunium(IV) Expanded Porphyrin Complexes.

Brewster JT 2nd, Mangel DN, Gaunt AJ, Saunders DP, Zafar H, Lynch VM, Boreen MA, Garner ME, Goodwin CAP, Settineri NS, Arnold J, Sessler JL.

J Am Chem Soc. 2019 Nov 6;141(44):17867-17874. doi: 10.1021/jacs.9b09123. Epub 2019 Oct 25.

PMID:
31609114
8.

Dormancy, Diapause, and the Role of the Circadian System in Insect Photoperiodism.

Saunders DS.

Annu Rev Entomol. 2019 Oct 8. doi: 10.1146/annurev-ento-011019-025116. [Epub ahead of print]

PMID:
31594413
9.

Generation of Norovirus-Specific T-Cells from Human Donors with Extensive Cross-Reactivity to Variant Sequences: Implications for Immunotherapy.

Hanajiri R, Sani GM, Saunders D, Hanley PJ, Chopra A, Mallal SA, Sosnovtsev SV, Cohen JI, Green KY, Bollard CM, Keller MD.

J Infect Dis. 2019 Sep 28. pii: jiz491. doi: 10.1093/infdis/jiz491. [Epub ahead of print]

PMID:
31562500
10.

Efficient Transmission of Mixed Plasmodium falciparum/vivax Infections From Humans to Mosquitoes.

Balasubramanian S, Rahman RS, Lon C, Parobek C, Ubalee R, Hathaway N, Kuntawunginn W, My M, Vy D, Saxe J, Lanteri C, Lin FC, Spring M, Meshnick SR, Juliano JJ, Saunders DL, Lin JT.

J Infect Dis. 2019 Sep 24. pii: jiz388. doi: 10.1093/infdis/jiz388. [Epub ahead of print]

PMID:
31549156
11.

Medulloblastoma rendered susceptible to NK-cell attack by TGFβ neutralization.

Powell AB, Yadavilli S, Saunders D, Van Pelt S, Chorvinsky E, Burga RA, Albihani S, Hanley PJ, Xu Z, Pei Y, Yvon ES, Hwang EI, Bollard CM, Nazarian J, Cruz CRY.

J Transl Med. 2019 Sep 23;17(1):321. doi: 10.1186/s12967-019-2055-4.

12.

Improved robustness of reinforcement learning policies upon conversion to spiking neuronal network platforms applied to Atari Breakout game.

Patel D, Hazan H, Saunders DJ, Siegelmann HT, Kozma R.

Neural Netw. 2019 Aug 25. pii: S0893-6080(19)30226-6. doi: 10.1016/j.neunet.2019.08.009. [Epub ahead of print]

PMID:
31500931
13.

Locally connected spiking neural networks for unsupervised feature learning.

Saunders DJ, Patel D, Hazan H, Siegelmann HT, Kozma R.

Neural Netw. 2019 Nov;119:332-340. doi: 10.1016/j.neunet.2019.08.016. Epub 2019 Aug 26.

PMID:
31499357
14.

Anti-inflammatory agent, OKN-007, reverses long-term neuroinflammatory responses in a rat encephalopathy model as assessed by multi-parametric MRI: implications for aging-associated neuroinflammation.

Towner RA, Saunders D, Smith N, Gulej R, McKenzie T, Lawrence B, Morton KA.

Geroscience. 2019 Aug;41(4):483-494. doi: 10.1007/s11357-019-00094-y. Epub 2019 Sep 2.

15.

Vascular Instability and Neurological Morbidity in Sickle Cell Disease: An Integrative Framework.

Stotesbury H, Kawadler JM, Hales PW, Saunders DE, Clark CA, Kirkham FJ.

Front Neurol. 2019 Aug 13;10:871. doi: 10.3389/fneur.2019.00871. eCollection 2019.

16.

Using MRI to measure in vivo free radical production and perfusion dynamics in a mouse model of elevated oxidative stress and neurogenic atrophy.

Ahn B, Smith N, Saunders D, Ranjit R, Kneis P, Towner RA, Van Remmen H.

Redox Biol. 2019 Sep;26:101308. doi: 10.1016/j.redox.2019.101308. Epub 2019 Aug 21.

17.

Medication-Related Osteonecrosis of the Jaw: MASCC/ISOO/ASCO Clinical Practice Guideline Summary.

Shapiro CL, Yarom N, Peterson DE, Bohlke K, Saunders DP.

J Oncol Pract. 2019 Nov;15(11):603-606. doi: 10.1200/JOP.19.00384. Epub 2019 Aug 26. No abstract available.

PMID:
31449435
18.

MARPLE, a point-of-care, strain-level disease diagnostics and surveillance tool for complex fungal pathogens.

Radhakrishnan GV, Cook NM, Bueno-Sancho V, Lewis CM, Persoons A, Mitiku AD, Heaton M, Davey PE, Abeyo B, Alemayehu Y, Badebo A, Barnett M, Bryant R, Chatelain J, Chen X, Dong S, Henriksson T, Holdgate S, Justesen AF, Kalous J, Kang Z, Laczny S, Legoff JP, Lesch D, Richards T, Randhawa HS, Thach T, Wang M, Hovmøller MS, Hodson DP, Saunders DGO.

BMC Biol. 2019 Aug 13;17(1):65. doi: 10.1186/s12915-019-0684-y.

19.

A multicentre, randomized pilot trial comparing vascular access strategies for early stage breast cancer patients receiving non-trastuzumab containing chemotherapy.

Robinson A, Stober C, Fergusson D, Kehoe A, Bedard D, MacDonald F, Brunet MC, Saunders D, Mazzarello S, Vandermeer L, Joy AA, Awan A, Basulaiman B, Mallick R, Hutton B, Clemons M; REaCT investigators.

Breast Cancer Res Treat. 2019 Nov;178(2):337-345. doi: 10.1007/s10549-019-05388-5. Epub 2019 Aug 7.

PMID:
31392518
20.

Response to "Comment on 'Consulting the consultants: Avastin in the treatment of wet AMD'".

Mohamed R, Saunders DC, Mathews JP.

Eye (Lond). 2019 Nov;33(11):1822. doi: 10.1038/s41433-019-0533-9. Epub 2019 Jul 31. No abstract available.

PMID:
31367004
21.

Immunotherapy of Relapsed and Refractory Solid Tumors With Ex Vivo Expanded Multi-Tumor Associated Antigen Specific Cytotoxic T Lymphocytes: A Phase I Study.

Hont AB, Cruz CR, Ulrey R, O'Brien B, Stanojevic M, Datar A, Albihani S, Saunders D, Hanajiri R, Panchapakesan K, Darko S, Banerjee P, Fortiz MF, Hoq F, Lang H, Wang Y, Hanley PJ, Dome JS, Bollard CM, Meany HJ.

J Clin Oncol. 2019 Sep 10;37(26):2349-2359. doi: 10.1200/JCO.19.00177. Epub 2019 Jul 29.

22.

Medication-Related Osteonecrosis of the Jaw: MASCC/ISOO/ASCO Clinical Practice Guideline.

Yarom N, Shapiro CL, Peterson DE, Van Poznak CH, Bohlke K, Ruggiero SL, Migliorati CA, Khan A, Morrison A, Anderson H, Murphy BA, Alston-Johnson D, Mendes RA, Beadle BM, Jensen SB, Saunders DP.

J Clin Oncol. 2019 Sep 1;37(25):2270-2290. doi: 10.1200/JCO.19.01186. Epub 2019 Jul 22.

PMID:
31329513
23.

Circulation and characterization of seasonal influenza viruses in Cambodia, 2012-2015.

Horwood PF, Karlsson EA, Horm SV, Ly S, Heng S, Chin S, Darapheak C, Saunders D, Chanthap L, Rith S, Y P, Chea KL, Sar B, Parry A, Ieng V, Tsuyouka R, Deng YM, Hurt AC, Barr IG, Komadina N, Buchy P, Dussart P.

Influenza Other Respir Viruses. 2019 Sep;13(5):465-476. doi: 10.1111/irv.12647. Epub 2019 Jun 28.

24.

A global surveillance system for crop diseases.

Carvajal-Yepes M, Cardwell K, Nelson A, Garrett KA, Giovani B, Saunders DGO, Kamoun S, Legg JP, Verdier V, Lessel J, Neher RA, Day R, Pardey P, Gullino ML, Records AR, Bextine B, Leach JE, Staiger S, Tohme J.

Science. 2019 Jun 28;364(6447):1237-1239. doi: 10.1126/science.aaw1572. No abstract available.

PMID:
31249049
25.

Expecting the unexpected: factors influencing the emergence of fungal and oomycete plant pathogens.

Corredor-Moreno P, Saunders DGO.

New Phytol. 2019 Jun 21. doi: 10.1111/nph.16007. [Epub ahead of print]

PMID:
31225901
26.

Genomic structure and diversity of Plasmodium falciparum in Southeast Asia reveal recent parasite migration patterns.

Shetty AC, Jacob CG, Huang F, Li Y, Agrawal S, Saunders DL, Lon C, Fukuda MM, Ringwald P, Ashley EA, Han KT, Hlaing TM, Nyunt MM, Silva JC, Stewart KE, Plowe CV, O'Connor TD, Takala-Harrison S; Artemisinin Resistance Confirmation, Characterization, and Containment (ARC3); Artemisinin Resistance Containment and Elimination (ARCE); Tracking Resistance to Artemisinin Collaboration (TRAC).

Nat Commun. 2019 Jun 17;10(1):2665. doi: 10.1038/s41467-019-10121-3.

27.

The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation.

Bax M, McKenna J, Do-Ha D, Stevens CH, Higginbottom S, Balez R, Cabral-da-Silva MEC, Farrawell NE, Engel M, Poronnik P, Yerbury JJ, Saunders DN, Ooi L.

Cells. 2019 Jun 13;8(6). pii: E581. doi: 10.3390/cells8060581.

28.

Transcranial Doppler and Magnetic Resonance in Tanzanian Children With Sickle Cell Disease.

Kija EN, Saunders DE, Munubhi E, Darekar A, Barker S, Cox TCS, Mango M, Soka D, Komba J, Nkya DA, Cox SE, Kirkham FJ, Newton CRJC.

Stroke. 2019 Jul;50(7):1719-1726. doi: 10.1161/STROKEAHA.118.018920. Epub 2019 Jun 14.

29.

Identifying factors associated with sedentary time after stroke. Secondary analysis of pooled data from nine primary studies.

Hendrickx W, Riveros C, Askim T, Bussmann JBJ, Callisaya ML, Chastin SFM, Dean CM, Ezeugwu VE, Jones TM, Kuys SS, Mahendran N, Manns TJ, Mead G, Moore SA, Paul L, Pisters MF, Saunders DH, Simpson DB, Tieges Z, Verschuren O, English C.

Top Stroke Rehabil. 2019 Jul;26(5):327-334. doi: 10.1080/10749357.2019.1601419. Epub 2019 Apr 26.

PMID:
31025908
30.

The effects of yoga compared to active and inactive controls on physical function and health related quality of life in older adults- systematic review and meta-analysis of randomised controlled trials.

Sivaramakrishnan D, Fitzsimons C, Kelly P, Ludwig K, Mutrie N, Saunders DH, Baker G.

Int J Behav Nutr Phys Act. 2019 Apr 5;16(1):33. doi: 10.1186/s12966-019-0789-2.

31.

Experimental Demonstration of Quantum Effects in the Operation of Microscopic Heat Engines.

Klatzow J, Becker JN, Ledingham PM, Weinzetl C, Kaczmarek KT, Saunders DJ, Nunn J, Walmsley IA, Uzdin R, Poem E.

Phys Rev Lett. 2019 Mar 22;122(11):110601. doi: 10.1103/PhysRevLett.122.110601.

PMID:
30951320
32.

Targeting ELTD1, an angiogenesis marker for glioblastoma (GBM), also affects VEGFR2: molecular-targeted MRI assessment.

Ziegler J, Zalles M, Smith N, Saunders D, Lerner M, Fung KM, Patel M, Wren JD, Lupu F, Battiste J, Towner RA.

Am J Nucl Med Mol Imaging. 2019 Feb 15;9(1):93-109. eCollection 2019.

33.

Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.

Kennedy SP, Han JZR, Portman N, Nobis M, Hastings JF, Murphy KJ, Latham SL, Cadell AL, Miladinovic D, Marriott GR, O'Donnell YEI, Shearer RF, Williams JT, Munoz AG, Cox TR, Watkins DN, Saunders DN, Timpson P, Lim E, Kolch W, Croucher DR.

Breast Cancer Res. 2019 Mar 21;21(1):43. doi: 10.1186/s13058-019-1127-y.

34.

Postoperative critical care and high-acuity care provision in the United Kingdom, Australia, and New Zealand.

Wong DJN, Popham S, Wilson AM, Barneto LM, Lindsay HA, Farmer L, Saunders D, Wallace S, Campbell D, Myles PS, Harris SK, Moonesinghe SR; SNAP-2: EPICCS collaborators; Study Steering Group.

Br J Anaesth. 2019 Apr;122(4):460-469. doi: 10.1016/j.bja.2018.12.026. Epub 2019 Feb 8.

35.

Index of Pain Experience in Sickle Cell Anaemia (IPESCA): development from daily pain diaries and initial findings from use with children and adults with sickle cell anaemia.

Kawadler JM, Slee A, Stotesbury H, Koelbel M, Balfour P, Saunders DE, Rees D, Howard J, Inusa B, Pelidis M, Kesse-Adu R, Chakravorty S, Awogbade M, Clark CA, Kirkham FJ, Liossi C.

Br J Haematol. 2019 Jul;186(2):360-363. doi: 10.1111/bjh.15841. Epub 2019 Mar 5. No abstract available.

PMID:
30836440
36.

Assessment of the Utility of a Vascular Early Warning System Device in the Assessment of Peripheral Arterial Disease in Patients with Diabetes and Incompressible Vessels.

Saunders DJ, Bleasdale L, Summerton L, Hancock A, Homer-Vanniasinkam S, Russell DA.

Ann Vasc Surg. 2019 Jul;58:160-165. doi: 10.1016/j.avsg.2018.11.033. Epub 2019 Feb 13.

PMID:
30769053
37.

Consulting the patients: Avastin in the treatment of Wet AMD (Part II).

Mohamed R, Saunders DC, Mathews JP.

Eye (Lond). 2019 Jun;33(6):871-873. doi: 10.1038/s41433-019-0366-6. Epub 2019 Feb 13. No abstract available.

PMID:
30760898
38.

Tackling the re-emergence of wheat stem rust in Western Europe.

Saunders DGO, Pretorius ZA, Hovmøller MS.

Commun Biol. 2019 Feb 4;2:51. doi: 10.1038/s42003-019-0294-9. eCollection 2019.

39.

People With Central Vision Loss Have Difficulty Watching Videos.

Costela FM, Saunders DR, Rose DJ, Katjezovic S, Reeves SM, Woods RL.

Invest Ophthalmol Vis Sci. 2019 Jan 2;60(1):358-364. doi: 10.1167/iovs.18-25540.

40.

Single-Dose Tafenoquine to Prevent Relapse of Plasmodium vivax Malaria.

Lacerda MVG, Llanos-Cuentas A, Krudsood S, Lon C, Saunders DL, Mohammed R, Yilma D, Batista Pereira D, Espino FEJ, Mia RZ, Chuquiyauri R, Val F, Casapía M, Monteiro WM, Brito MAM, Costa MRF, Buathong N, Noedl H, Diro E, Getie S, Wubie KM, Abdissa A, Zeynudin A, Abebe C, Tada MS, Brand F, Beck HP, Angus B, Duparc S, Kleim JP, Kellam LM, Rousell VM, Jones SW, Hardaker E, Mohamed K, Clover DD, Fletcher K, Breton JJ, Ugwuegbulam CO, Green JA, Koh GCKW.

N Engl J Med. 2019 Jan 17;380(3):215-228. doi: 10.1056/NEJMoa1710775.

41.

Extracellular Fatty Acids Are the Major Contributor to Lipid Synthesis in Prostate Cancer.

Balaban S, Nassar ZD, Zhang AY, Hosseini-Beheshti E, Centenera MM, Schreuder M, Lin HM, Aishah A, Varney B, Liu-Fu F, Lee LS, Nagarajan SR, Shearer RF, Hardie RA, Raftopulos NL, Kakani MS, Saunders DN, Holst J, Horvath LG, Butler LM, Hoy AJ.

Mol Cancer Res. 2019 Apr;17(4):949-962. doi: 10.1158/1541-7786.MCR-18-0347. Epub 2019 Jan 15.

PMID:
30647103
42.

Should we be moving to a national standardized non-gadolinium MR imaging protocol for the surveillance of vestibular schwannomas?

Currie S, Saunders D, Macmullen-Price J, Verma S, Ayres P, Tait C, Harwood C, Scarsbrook A, Craven IJ.

Br J Radiol. 2019 Apr;92(1096):20180833. doi: 10.1259/bjr.20180833. Epub 2019 Jan 23.

PMID:
30633539
43.

BindsNET: A Machine Learning-Oriented Spiking Neural Networks Library in Python.

Hazan H, Saunders DJ, Khan H, Patel D, Sanghavi DT, Siegelmann HT, Kozma R.

Front Neuroinform. 2018 Dec 12;12:89. doi: 10.3389/fninf.2018.00089. eCollection 2018.

44.

Immunomodulatory response of layered small intestinal submucosa in a rat bladder regeneration model.

Xia D, Yang Q, Fung KM, Towner RA, Smith N, Saunders D, Greenwood-Van Meerveld B, Kropp BP, Madihally SV, Lin HK.

J Biomed Mater Res B Appl Biomater. 2019 Aug;107(6):1960-1969. doi: 10.1002/jbm.b.34289. Epub 2018 Dec 6.

PMID:
30521124
45.

Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks.

Haliyur R, Tong X, Sanyoura M, Shrestha S, Lindner J, Saunders DC, Aramandla R, Poffenberger G, Redick SD, Bottino R, Prasad N, Levy SE, Blind RD, Harlan DM, Philipson LH, Stein RW, Brissova M, Powers AC.

J Clin Invest. 2019 Jan 2;129(1):246-251. doi: 10.1172/JCI121994. Epub 2018 Dec 3.

46.

Neuroimaging in patients with sickle cell anemia: capacity building in Africa.

Jacob M, Saunders DE, Kawadler JM, Mussa B, Murdoch R, Lapidaire W, Tluway F, Kazema RR, Nkya S, Ahmed M, Kija E, Fundikira L, Kussaga F, Darekar A, Tutuba H, Shmueli K, Clark CA, Makani J, Kirkham FJ.

Blood Adv. 2018 Nov 30;2(Suppl 1):26-29. doi: 10.1182/bloodadvances.2018GS112714. No abstract available.

47.

OKN-007 Increases temozolomide (TMZ) Sensitivity and Suppresses TMZ-Resistant Glioblastoma (GBM) Tumor Growth.

Towner RA, Smith N, Saunders D, Brown CA, Cai X, Ziegler J, Mallory S, Dozmorov MG, Coutinho De Souza P, Wiley G, Kim K, Kang S, Kong DS, Kim YT, Fung KM, Wren JD, Battiste J.

Transl Oncol. 2019 Feb;12(2):320-335. doi: 10.1016/j.tranon.2018.10.002. Epub 2018 Nov 20.

48.

Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic β Cells for In Vitro and In Vivo Analysis.

Saunders DC, Brissova M, Phillips N, Shrestha S, Walker JT, Aramandla R, Poffenberger G, Flaherty DK, Weller KP, Pelletier J, Cooper T, Goff MT, Virostko J, Shostak A, Dean ED, Greiner DL, Shultz LD, Prasad N, Levy SE, Carnahan RH, Dai C, Sévigny J, Powers AC.

Cell Metab. 2019 Mar 5;29(3):745-754.e4. doi: 10.1016/j.cmet.2018.10.007. Epub 2018 Nov 15.

PMID:
30449685
49.

Consulting the consultants: Avastin in the treatment of wet AMD.

Mohamed R, Saunders DC, Mathews JP.

Eye (Lond). 2019 Apr;33(4):529-531. doi: 10.1038/s41433-018-0260-7. Epub 2018 Nov 5. No abstract available.

PMID:
30397253
50.

Cluster-randomized trial of monthly malaria prophylaxis versus focused screening and treatment: a study protocol to define malaria elimination strategies in Cambodia.

Manning J, Lon C, Spring M, Wojnarski M, Somethy S, Chann S, Gosi P, Soveasna K, Sriwichai S, Kuntawunginn W, Fukuda MM, Smith PL, Rekol H, Sinoun M, So M, Lin J, Satharath P, Saunders D.

Trials. 2018 Oct 16;19(1):558. doi: 10.1186/s13063-018-2931-x.

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