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Items: 27

1.

Synthesis of Densely Functionalized N-Alkenyl 2-Pyridones via Benzyne-Induced Ring Opening of Thiazolino-Fused 2-Pyridones.

Singh P, Cairns AG, Adolfsson DE, Ådén J, Sauer UH, Almqvist F.

Org Lett. 2019 Aug 16. doi: 10.1021/acs.orglett.9b02549. [Epub ahead of print]

PMID:
31419146
2.

The Y233 gatekeeper of DmpR modulates effector-responsive transcriptional control of σ54 -RNA polymerase.

Seibt H, Sauer UH, Shingler V.

Environ Microbiol. 2019 Apr;21(4):1321-1330. doi: 10.1111/1462-2920.14567. Epub 2019 Mar 7.

PMID:
30773776
3.

Author Correction: Active-site plasticity revealed in the asymmetric dimer of AnPrx6 the 1-Cys peroxiredoxin and molecular chaperone from Anabaena sp. PCC 7120.

Mishra Y, Hall M, Locmelis R, Nam K, Söderberg CAG, Storm P, Chaurasia N, Rai LC, Jansson S, Schröder WP, Sauer UH.

Sci Rep. 2018 May 30;8(1):8658. doi: 10.1038/s41598-018-26715-8.

4.

Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes.

Kulén M, Lindgren M, Hansen S, Cairns AG, Grundström C, Begum A, van der Lingen I, Brännström K, Hall M, Sauer UH, Johansson J, Sauer-Eriksson AE, Almqvist F.

J Med Chem. 2018 May 10;61(9):4165-4175. doi: 10.1021/acs.jmedchem.8b00289. Epub 2018 Apr 27.

PMID:
29667825
5.

Molecular mechanism of ATP versus GTP selectivity of adenylate kinase.

Rogne P, Rosselin M, Grundström C, Hedberg C, Sauer UH, Wolf-Watz M.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3012-3017. doi: 10.1073/pnas.1721508115. Epub 2018 Mar 5.

6.

Active-site plasticity revealed in the asymmetric dimer of AnPrx6 the 1-Cys peroxiredoxin and molecular chaperone from Anabaena sp. PCC 7210.

Mishra Y, Hall M, Locmelis R, Nam K, Söderberg CAG, Storm P, Chaurasia N, Rai LC, Jansson S, Schröder WP, Sauer UH.

Sci Rep. 2017 Dec 7;7(1):17151. doi: 10.1038/s41598-017-17044-3. Erratum in: Sci Rep. 2018 May 30;8(1):8658.

7.

Structural basis for ligand binding to an enzyme by a conformational selection pathway.

Kovermann M, Grundström C, Sauer-Eriksson AE, Sauer UH, Wolf-Watz M.

Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):6298-6303. doi: 10.1073/pnas.1700919114. Epub 2017 May 30.

8.

Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria.

Hall M, Grundström C, Begum A, Lindberg MJ, Sauer UH, Almqvist F, Johansson J, Sauer-Eriksson AE.

Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14733-14738. doi: 10.1073/pnas.1614028114. Epub 2016 Dec 5.

9.

Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA.

Good JA, Andersson C, Hansen S, Wall J, Krishnan KS, Begum A, Grundström C, Niemiec MS, Vaitkevicius K, Chorell E, Wittung-Stafshede P, Sauer UH, Sauer-Eriksson AE, Almqvist F, Johansson J.

Cell Chem Biol. 2016 Mar 17;23(3):404-14. doi: 10.1016/j.chembiol.2016.02.013.

10.

Structural basis for catalytically restrictive dynamics of a high-energy enzyme state.

Kovermann M, Ådén J, Grundström C, Sauer-Eriksson AE, Sauer UH, Wolf-Watz M.

Nat Commun. 2015 Jul 3;6:7644. doi: 10.1038/ncomms8644.

11.

Small molecule screening for inhibitors of the YopH phosphatase of Yersinia pseudotuberculosis.

Eriksson J, Grundström C, Sauer-Eriksson AE, Sauer UH, Wolf-Watz H, Elofsson M.

Adv Exp Med Biol. 2012;954:357-63. doi: 10.1007/978-1-4614-3561-7_43. No abstract available.

PMID:
22782782
12.

Redox-mediated mechanisms regulate DNA binding activity of the G-group of basic region leucine zipper (bZIP) transcription factors in Arabidopsis.

Shaikhali J, Norén L, de Dios Barajas-López J, Srivastava V, König J, Sauer UH, Wingsle G, Dietz KJ, Strand Å.

J Biol Chem. 2012 Aug 10;287(33):27510-25. doi: 10.1074/jbc.M112.361394. Epub 2012 Jun 20.

13.

Purification, crystallization and preliminary X-ray analysis of PPD6, a PsbP-domain protein from Arabidopsis thaliana.

Hall M, Kieselbach T, Sauer UH, Schröder WP.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Mar 1;68(Pt 3):278-80. doi: 10.1107/S1744309111042023. Epub 2012 Feb 22.

14.

Crystallization and preliminary X-ray analysis of the Entamoeba histolytica α-actinin-2 rod domain.

Addario B, Huang S, Sauer UH, Backman L.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Oct 1;67(Pt 10):1214-7. doi: 10.1107/S1744309111026066. Epub 2011 Sep 24.

15.

Expression, purification, crystallization and preliminary X-ray crystallographic studies of alkyl hydroperoxide reductase (AhpC) from the cyanobacterium Anabaena sp. PCC 7120.

Mishra Y, Hall M, Chaurasia N, Rai LC, Jansson S, Schröder WP, Sauer UH.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Oct 1;67(Pt 10):1203-6. doi: 10.1107/S1744309111025747. Epub 2011 Sep 24.

16.

Accurate domain identification with structure-anchored hidden Markov models, saHMMs.

Tångrot JE, Kågström B, Sauer UH.

Proteins. 2009 Aug 1;76(2):343-52. doi: 10.1002/prot.22349.

PMID:
19173309
17.

OnD-CRF: predicting order and disorder in proteins using [corrected] conditional random fields.

Wang L, Sauer UH.

Bioinformatics. 2008 Jun 1;24(11):1401-2. doi: 10.1093/bioinformatics/btn132. Epub 2008 Apr 21. Erratum in: Bioinformatics. 2008 Jul 1;24(13):1562.

18.

FISH--family identification of sequence homologues using structure anchored hidden Markov models.

Tångrot J, Wang L, Kågström B, Sauer UH.

Nucleic Acids Res. 2006 Jul 1;34(Web Server issue):W10-4.

19.

The transthyretin-related protein: structural investigation of a novel protein family.

Lundberg E, Bäckström S, Sauer UH, Sauer-Eriksson AE.

J Struct Biol. 2006 Sep;155(3):445-57. Epub 2006 May 8.

PMID:
16723258
20.

Crystallization and X-ray analysis of a bacterial non-haem iron-containing phenylalanine hydroxylase from the Gram-negative opportunistic pathogen Pseudomonas aeruginosa.

Ekström F, Stier G, Eaton JT, Sauer UH.

Acta Crystallogr D Biol Crystallogr. 2003 Jul;59(Pt 7):1310-2. Epub 2003 Jun 27.

PMID:
12832796
21.

Crystallization of the actin-binding domain of human alpha-actinin: analysis of microcrystals of SeMet-labelled protein.

Ekström F, Stier G, Sauer UH.

Acta Crystallogr D Biol Crystallogr. 2003 Apr;59(Pt 4):724-6. Epub 2003 Mar 25.

PMID:
12657793
22.

The RUNX1 Runt domain at 1.25A resolution: a structural switch and specifically bound chloride ions modulate DNA binding.

Bäckström S, Wolf-Watz M, Grundström C, Härd T, Grundström T, Sauer UH.

J Mol Biol. 2002 Sep 13;322(2):259-72.

PMID:
12217689
23.

Structural basis for thermophilic protein stability: structures of thermophilic and mesophilic malate dehydrogenases.

Dalhus B, Saarinen M, Sauer UH, Eklund P, Johansson K, Karlsson A, Ramaswamy S, Bjørk A, Synstad B, Naterstad K, Sirevåg R, Eklund H.

J Mol Biol. 2002 May 3;318(3):707-21.

PMID:
12054817
24.

Crystallization and preliminary studies of the DNA-binding runt domain of AML1.

Bäckström S, Huang SH, Wolf-Watz M, Xie XQ, Härd T, Grundström T, Sauer UH.

Acta Crystallogr D Biol Crystallogr. 2001 Feb;57(Pt 2):269-71.

PMID:
11173476

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