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Items: 1 to 50 of 434

1.

Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart.

Vidal R, Wagner JUG, Braeuning C, Fischer C, Patrick R, Tombor L, Muhly-Reinholz M, John D, Kliem M, Conrad T, Guimarães-Camboa N, Harvey R, Dimmeler S, Sauer S.

JCI Insight. 2019 Nov 14;4(22). pii: 131092. doi: 10.1172/jci.insight.131092.

PMID:
31723062
2.

ADP-dependent glucokinase regulates energy metabolism via ER-localized glucose sensing.

Imle R, Wang BT, Stützenberger N, Birkenhagen J, Tandon A, Carl M, Himmelreich N, Thiel C, Gröne HJ, Poschet G, Völkers M, Gülow K, Schröder A, Carillo S, Mittermayr S, Bones J, Kamiński MM, Kölker S, Sauer SW.

Sci Rep. 2019 Oct 3;9(1):14248. doi: 10.1038/s41598-019-50566-6.

3.

Noniterative Doubles Corrections to the Random Phase and Higher Random Phase Approximations: Singlet and Triplet Excitation Energies.

Haase PAB, Faber R, Provasi PF, Sauer SPA.

J Comput Chem. 2019 Oct 1. doi: 10.1002/jcc.26074. [Epub ahead of print]

PMID:
31576598
4.

R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon.

Harnack C, Berger H, Antanaviciute A, Vidal R, Sauer S, Simmons A, Meyer TF, Sigal M.

Nat Commun. 2019 Sep 25;10(1):4368. doi: 10.1038/s41467-019-12349-5.

5.

The phospholipase C inhibitor U73122 is a potent agonist of the polymodal transient receptor potential ankyrin type 1 (TRPA1) receptor channel.

Neacsu C, Sauer SK, Reeh PW, Babes A.

Naunyn Schmiedebergs Arch Pharmacol. 2019 Sep 3. doi: 10.1007/s00210-019-01722-2. [Epub ahead of print]

PMID:
31482262
6.

Clonality of circulating tumor cells in breast cancer brain metastasis patients.

Riebensahm C, Joosse SA, Mohme M, Hanssen A, Matschke J, Goy Y, Witzel I, Lamszus K, Kropidlowski J, Petersen C, Kolb-Kokocinski A, Sauer S, Borgmann K, Glatzel M, Müller V, Westphal M, Riethdorf S, Pantel K, Wikman H.

Breast Cancer Res. 2019 Sep 3;21(1):101. doi: 10.1186/s13058-019-1184-2.

7.

Cystic transformation of focal lesions after therapy is associated with remission but adverse outcome in myeloma.

Merz M, Hielscher T, Mai EK, Seckinger A, Hose D, Jauch A, Sauer S, Luntz S, Bertsch U, Raab MS, Neben K, Salwender H, Blau IW, Lindemann HW, Dürig J, Scheid C, Haenel M, Weisel K, Weber T, Delorme S, Goldschmidt H, Hillengass J.

Blood Cancer J. 2019 Aug 27;9(9):71. doi: 10.1038/s41408-019-0235-3. No abstract available.

8.

Selective deployment of transcription factor paralogs with submaximal strength facilitates gene regulation in the immune system.

Bruno L, Ramlall V, Studer RA, Sauer S, Bradley D, Dharmalingam G, Carroll T, Ghoneim M, Chopin M, Nutt SL, Elderkin S, Rueda DS, Fisher AG, Siggers T, Beltrao P, Merkenschlager M.

Nat Immunol. 2019 Oct;20(10):1372-1380. doi: 10.1038/s41590-019-0471-5. Epub 2019 Aug 26.

PMID:
31451789
9.

Pedestrian hit by a car impacted metal pole: reconstructing the head load.

Wagner R, Muggenthaler H, Sauer S, Mall G, Hubig M.

Int J Legal Med. 2019 Aug 7. doi: 10.1007/s00414-019-02133-x. [Epub ahead of print]

PMID:
31388796
10.

Characterization of bacterial communities in wastewater with enhanced taxonomic resolution by full-length 16S rRNA sequencing.

Numberger D, Ganzert L, Zoccarato L, Mühldorfer K, Sauer S, Grossart HP, Greenwood AD.

Sci Rep. 2019 Jul 4;9(1):9673. doi: 10.1038/s41598-019-46015-z.

11.

R-spondin-3 induces secretory, antimicrobial Lgr5+ cells in the stomach.

Sigal M, Reinés MDM, Müllerke S, Fischer C, Kapalczynska M, Berger H, Bakker ERM, Mollenkopf HJ, Rothenberg ME, Wiedenmann B, Sauer S, Meyer TF.

Nat Cell Biol. 2019 Jul;21(7):812-823. doi: 10.1038/s41556-019-0339-9. Epub 2019 Jun 24.

PMID:
31235935
12.

Methylglyoxal causes pain and hyperalgesia in human through C-fiber activation.

Düll MM, Riegel K, Tappenbeck J, Ries V, Strupf M, Fleming T, Sauer SK, Namer B.

Pain. 2019 Nov;160(11):2497-2507. doi: 10.1097/j.pain.0000000000001644.

PMID:
31219946
13.

Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus.

Wiechmann T, Röh S, Sauer S, Czamara D, Arloth J, Ködel M, Beintner M, Knop L, Menke A, Binder EB, Provençal N.

Clin Epigenetics. 2019 May 23;11(1):83. doi: 10.1186/s13148-019-0682-5.

14.

Signals trigger state-specific transcriptional programs to support diversity and homeostasis in immune cells.

Fischer C, Metsger M, Bauch S, Vidal R, Böttcher M, Grote P, Kliem M, Sauer S.

Sci Signal. 2019 May 14;12(581). pii: eaao5820. doi: 10.1126/scisignal.aao5820.

PMID:
31088978
15.

Author Correction: High-resolution record reveals climate-driven environmental and sedimentary changes in an active rift.

McNeill LC, Shillington DJ, Carter GDO, Everest JD, Gawthorpe RL, Miller C, Phillips MP, Collier REL, Cvetkoska A, De Gelder G, Diz P, Doan ML, Ford M, Geraga M, Gillespie J, Hemelsdaël R, Herrero-Bervera E, Ismaiel M, Janikian L, Kouli K, Le Ber E, Li S, Maffione M, Mahoney C, Machlus ML, Michas G, Nixon CW, Oflaz SA, Omale AP, Panagiotopoulos K, Pechlivanidou S, Sauer S, Seguin J, Sergiou S, Zakharova NV, Green S.

Sci Rep. 2019 Apr 19;9(1):6519. doi: 10.1038/s41598-019-42749-y.

16.

QDPR homologues in Danio rerio regulate melanin synthesis, early gliogenesis, and glutamine homeostasis.

Breuer M, Guglielmi L, Zielonka M, Hemberger V, Kölker S, Okun JG, Hoffmann GF, Carl M, Sauer SW, Opladen T.

PLoS One. 2019 Apr 17;14(4):e0215162. doi: 10.1371/journal.pone.0215162. eCollection 2019.

17.

The influence of tibial slope on anterior cruciate ligament graft failure risk is dependent on graft positioning.

Sauer S, English R, Clatworthy M.

J Orthop Surg (Hong Kong). 2019 Jan-Apr;27(1):2309499019834674. doi: 10.1177/2309499019834674.

PMID:
30852943
18.

High-resolution record reveals climate-driven environmental and sedimentary changes in an active rift.

McNeill LC, Shillington DJ, Carter GDO, Everest JD, Gawthorpe RL, Miller C, Phillips MP, Collier REL, Cvetkoska A, De Gelder G, Diz P, Doan ML, Ford M, Geraga M, Gillespie J, Hemelsdaël R, Herrero-Bervera E, Ismaiel M, Janikian L, Kouli K, Le Ber E, Li S, Maffione M, Mahoney C, Machlus ML, Michas G, Nixon CW, Oflaz SA, Omale AP, Panagiotopoulos K, Pechlivanidou S, Sauer S, Seguin J, Sergiou S, Zakharova NV, Green S.

Sci Rep. 2019 Feb 28;9(1):3116. doi: 10.1038/s41598-019-40022-w. Erratum in: Sci Rep. 2019 Apr 19;9(1):6519.

19.

Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined.

Kaleviste E, Saare M, Leahy TR, Bondet V, Duffy D, Mogensen TH, Jørgensen SE, Nurm H, Ip W, Davies EG, Sauer S, Syvänen AC, Milani L, Peterson P, Kisand K.

Eur J Immunol. 2019 May;49(5):790-800. doi: 10.1002/eji.201847955. Epub 2019 Mar 7.

PMID:
30801692
20.

Quantitative dynamic 18F-fluorodeoxyglucose positron emission tomography/computed tomography before autologous stem cell transplantation predicts survival in multiple myeloma.

Sachpekidis C, Merz M, Kopp-Schneider A, Jauch A, Raab MS, Sauer S, Hillengass J, Goldschmidt H, Dimitrakopoulou-Strauss A.

Haematologica. 2019 Sep;104(9):e420-e423. doi: 10.3324/haematol.2018.213041. Epub 2019 Feb 14. No abstract available.

21.

Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma.

Haage V, Semtner M, Vidal RO, Hernandez DP, Pong WW, Chen Z, Hambardzumyan D, Magrini V, Ly A, Walker J, Mardis E, Mertins P, Sauer S, Kettenmann H, Gutmann DH.

Acta Neuropathol Commun. 2019 Feb 14;7(1):20. doi: 10.1186/s40478-019-0665-y.

22.

High-risk breast cancer surveillance with MRI: 10-year experience from the German consortium for hereditary breast and ovarian cancer.

Bick U, Engel C, Krug B, Heindel W, Fallenberg EM, Rhiem K, Maintz D, Golatta M, Speiser D, Rjosk-Dendorfer D, Lämmer-Skarke I, Dietzel F, Schäfer KWF, Leinert E, Weigel S, Sauer S, Pertschy S, Hofmockel T, Hagert-Winkler A, Kast K, Quante A, Meindl A, Kiechle M, Loeffler M, Schmutzler RK; German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC).

Breast Cancer Res Treat. 2019 May;175(1):217-228. doi: 10.1007/s10549-019-05152-9. Epub 2019 Feb 6.

PMID:
30725383
23.

Entropy/Enthalpy Compensation in Anion Binding: Biotin[6]uril and Biotin-l-sulfoxide[6]uril Reveal Strong Solvent Dependency.

Andersen NN, Eriksen K, Lisbjerg M, Ottesen ME, Milhøj BO, Sauer SPA, Pittelkow M.

J Org Chem. 2019 Mar 1;84(5):2577-2584. doi: 10.1021/acs.joc.8b02797. Epub 2019 Feb 19.

PMID:
30721069
24.

The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer.

Zhu Q, Fang L, Heuberger J, Kranz A, Schipper J, Scheckenbach K, Vidal RO, Sunaga-Franze DY, Müller M, Wulf-Goldenberg A, Sauer S, Birchmeier W.

Cell Rep. 2019 Jan 8;26(2):415-428.e5. doi: 10.1016/j.celrep.2018.12.059.

25.

A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding.

Hernáez B, Alonso-Lobo JM, Montanuy I, Fischer C, Sauer S, Sigal L, Sevilla N, Alcamí A.

Nat Commun. 2018 Dec 21;9(1):5440. doi: 10.1038/s41467-018-07772-z.

26.

RPA(D) and HRPA(D): Two new models for calculations of NMR indirect nuclear spin-spin coupling constants.

Schnack-Petersen AK, Haase PAB, Faber R, Provasi PF, Sauer SPA.

J Comput Chem. 2018 Dec 15;39(32):2647-2666. doi: 10.1002/jcc.25712.

PMID:
30515901
27.

The influence of relativistic effects on nuclear magnetic resonance spin-spin coupling constant polarizabilities of H2 O2 , H2 S2 , H2 Se2 , and H2 Te2.

Pagola GI, Larsen MAB, Ferraro M, Sauer SPA.

J Comput Chem. 2018 Dec 5;39(31):2589-2600. doi: 10.1002/jcc.25648.

PMID:
30485474
28.

Computational Prediction of 1 H and 13 C NMR Chemical Shifts for Protonated Alkylpyrroles: Electron Correlation and Not Solvation is the Salvation.

Lacerda EG Jr, Kamounah FS, Coutinho K, Sauer SPA, Hansen PE, Hammerich O.

Chemphyschem. 2019 Jan 7;20(1):78-91. doi: 10.1002/cphc.201801066. Epub 2018 Dec 7.

PMID:
30452112
29.

Phenotypic characterization and whole genome analysis of extended-spectrum beta-lactamase-producing bacteria isolated from dogs in Germany.

Boehmer T, Vogler AJ, Thomas A, Sauer S, Hergenroether M, Straubinger RK, Birdsell D, Keim P, Sahl JW, Williamson CHD, Riehm JM.

PLoS One. 2018 Oct 26;13(10):e0206252. doi: 10.1371/journal.pone.0206252. eCollection 2018.

30.

Chromatin accessibility dynamics across C. elegans development and ageing.

Jänes J, Dong Y, Schoof M, Serizay J, Appert A, Cerrato C, Woodbury C, Chen R, Gemma C, Huang N, Kissiov D, Stempor P, Steward A, Zeiser E, Sauer S, Ahringer J.

Elife. 2018 Oct 26;7. pii: e37344. doi: 10.7554/eLife.37344.

31.

The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory.

Daniel B, Nagy G, Czimmerer Z, Horvath A, Hammers DW, Cuaranta-Monroy I, Poliska S, Tzerpos P, Kolostyak Z, Hays TT, Patsalos A, Houtman R, Sauer S, Francois-Deleuze J, Rastinejad F, Balint BL, Sweeney HL, Nagy L.

Immunity. 2018 Oct 16;49(4):615-626.e6. doi: 10.1016/j.immuni.2018.09.005.

32.

Direct observation of Mg2+ complexes in ionic liquid solutions by 31Mg β-NMR spectroscopy.

Szunyogh D, McFadden RML, Karner VL, Chatzichristos A, Day Goodacre T, Dehn MH, Formenti L, Fujimoto D, Gottberg A, Kallenberg E, Kálomista I, Kiefl RF, Larsen FH, Lassen J, Levy CDP, Li R, MacFarlane WA, McKenzie I, Morris GD, Pallada S, Pearson MR, Sauer SPA, Schaffer P, Thulstrup PW, Hemmingsen L, Stachura M.

Dalton Trans. 2018 Oct 23;47(41):14431-14435. doi: 10.1039/c8dt02350f.

PMID:
30280170
33.

Local NGF and GDNF levels modulate morphology and function of porcine DRG neurites, In Vitro.

Klusch A, Gorzelanny C, Reeh PW, Schmelz M, Petersen M, Sauer SK.

PLoS One. 2018 Sep 27;13(9):e0203215. doi: 10.1371/journal.pone.0203215. eCollection 2018.

34.

Search for cis-acting factors and maternal effect variants in Silver-Russell patients with ICR1 hypomethylation and their mothers.

Soellner L, Kraft F, Sauer S, Begemann M, Kurth I, Elbracht M, Eggermann T.

Eur J Hum Genet. 2019 Jan;27(1):42-48. doi: 10.1038/s41431-018-0269-1. Epub 2018 Sep 14.

PMID:
30218098
35.

The Effect of Medial Tibial Slope on Anterior Tibial Translation and Short-Term ACL Reconstruction Outcome.

Sauer S, Clatworthy M.

Surg J (N Y). 2018 Sep 10;4(3):e160-e163. doi: 10.1055/s-0038-1669929. eCollection 2018 Jul.

36.

The Ratio of Tibial Slope and Meniscal Bone Angle for the Prediction of ACL Reconstruction Failure Risk.

Sauer S, English R, Clatworthy M.

Surg J (N Y). 2018 Aug 20;4(3):e152-e159. doi: 10.1055/s-0038-1668111. eCollection 2018 Jul.

37.

Development of polarization consistent basis sets for spin-spin coupling constant calculations for the atoms Li, Be, Na, and Mg.

Aggelund PA, Sauer SPA, Jensen F.

J Chem Phys. 2018 Jul 28;149(4):044117. doi: 10.1063/1.5034109.

PMID:
30068157
38.

Transportal central femoral tunnel placement has a significantly higher revision rate than transtibial AM femoral tunnel placement in hamstring ACL reconstruction.

Clatworthy M, Sauer S, Roberts T.

Knee Surg Sports Traumatol Arthrosc. 2019 Jan;27(1):124-129. doi: 10.1007/s00167-018-5036-x. Epub 2018 Jul 12.

PMID:
30003286
39.

HAM-TBS: high-accuracy methylation measurements via targeted bisulfite sequencing.

Roeh S, Wiechmann T, Sauer S, Ködel M, Binder EB, Provençal N.

Epigenetics Chromatin. 2018 Jul 4;11(1):39. doi: 10.1186/s13072-018-0209-x.

40.

A prospective study on serum Cytokeratin (CK)-18 and CK18 fragments as biomarkers of acute hepato-intestinal GVHD.

Sauer S, Hüsing J, Hajda J, Neumann F, Radujkovic A, Ho AD, Dreger P, Luft T.

Leukemia. 2018 Dec;32(12):2685-2692. doi: 10.1038/s41375-018-0183-0. Epub 2018 Jun 27.

PMID:
29950693
41.

Reliability and main findings of the flexible endoscopic evaluation of swallowing-Tensilon test in patients with myasthenia gravis and dysphagia.

Im S, Suntrup-Krueger S, Colbow S, Sauer S, Claus I, Meuth SG, Dziewas R, Warnecke T.

Eur J Neurol. 2018 Oct;25(10):1235-1242. doi: 10.1111/ene.13688. Epub 2018 Jun 22.

PMID:
29802670
42.

Z-dependence of mean excitation energies for second and third row atoms and their ions.

Sauer SPA, Sabin JR, Oddershede J.

J Chem Phys. 2018 May 7;148(17):174307. doi: 10.1063/1.5027708.

PMID:
29739214
43.

A Review of Casualties Transported to Role 2 Medical Treatment Facilities in Afghanistan.

Kotwal RS, Staudt AM, Trevino JD, Valdez-Delgado KK, Le TD, Gurney JM, Sauer SW, Shackelford SA, Stockinger ZT, Mann-Salinas EA.

Mil Med. 2018 Mar 1;183(suppl_1):134-145. doi: 10.1093/milmed/usx211. Review.

PMID:
29635602
44.

Loss of the Hematopoietic Stem Cell Factor GATA2 in the Osteogenic Lineage Impairs Trabecularization and Mechanical Strength of Bone.

Tolkachov A, Fischer C, Ambrosi TH, Bothe M, Han CT, Muenzner M, Mathia S, Salminen M, Seifert G, Thiele M, Duda GN, Meijsing SH, Sauer S, Schulz TJ, Schupp M.

Mol Cell Biol. 2018 May 29;38(12). pii: e00599-17. doi: 10.1128/MCB.00599-17. Print 2018 Jun 15.

45.

The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages.

Daniel B, Nagy G, Horvath A, Czimmerer Z, Cuaranta-Monroy I, Poliska S, Hays TT, Sauer S, Francois-Deleuze J, Nagy L.

Nucleic Acids Res. 2018 May 18;46(9):4425-4439. doi: 10.1093/nar/gky157.

46.

Theoretical study of the NMR chemical shift of Xe in supercritical condition.

Lacerda EG Jr, Sauer SPA, Mikkelsen KV, Coutinho K, Canuto S.

J Mol Model. 2018 Feb 20;24(3):62. doi: 10.1007/s00894-018-3600-4.

PMID:
29464335
47.

Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart.

Jabs M, Rose AJ, Lehmann LH, Taylor J, Moll I, Sijmonsma TP, Herberich SE, Sauer SW, Poschet G, Federico G, Mogler C, Weis EM, Augustin HG, Yan M, Gretz N, Schmid RM, Adams RH, Gröne HJ, Hell R, Okun JG, Backs J, Nawroth PP, Herzig S, Fischer A.

Circulation. 2018 Jun 12;137(24):2592-2608. doi: 10.1161/CIRCULATIONAHA.117.029733. Epub 2018 Jan 20.

PMID:
29353241
48.

The bioequivalence of a single intravenous administration of the anesthetic alfaxalone in cyclodextrin versus alfaxalone in cyclodextrin plus preservatives in cats.

Pasloske K, Ranasinghe MG, Sauer S, Hare J.

J Vet Pharmacol Ther. 2018 Jun;41(3):437-446. doi: 10.1111/jvp.12485. Epub 2018 Jan 19.

PMID:
29352472
49.

The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages.

Czimmerer Z, Daniel B, Horvath A, Rückerl D, Nagy G, Kiss M, Peloquin M, Budai MM, Cuaranta-Monroy I, Simandi Z, Steiner L, Nagy B Jr, Poliska S, Banko C, Bacso Z, Schulman IG, Sauer S, Deleuze JF, Allen JE, Benko S, Nagy L.

Immunity. 2018 Jan 16;48(1):75-90.e6. doi: 10.1016/j.immuni.2017.12.010.

50.

Perturbation-response genes reveal signaling footprints in cancer gene expression.

Schubert M, Klinger B, Klünemann M, Sieber A, Uhlitz F, Sauer S, Garnett MJ, Blüthgen N, Saez-Rodriguez J.

Nat Commun. 2018 Jan 2;9(1):20. doi: 10.1038/s41467-017-02391-6.

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