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Quantitative dynamic 18F-FDG PET/CT before autologous stem cell transplantation predicts survival in multiple myeloma.

Sachpekidis C, Merz M, Kopp-Schneider A, Jauch A, Raab MS, Sauer S, Hillengass J, Goldschmidt H, Dimitrakopoulou-Strauss A.

Haematologica. 2019 Feb 14. pii: haematol.2018.213041. doi: 10.3324/haematol.2018.213041. [Epub ahead of print]


Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma.

Haage V, Semtner M, Vidal RO, Hernandez DP, Pong WW, Chen Z, Hambardzumyan D, Magrini V, Ly A, Walker J, Mardis E, Mertins P, Sauer S, Kettenmann H, Gutmann DH.

Acta Neuropathol Commun. 2019 Feb 14;7(1):20. doi: 10.1186/s40478-019-0665-y.


High-risk breast cancer surveillance with MRI: 10-year experience from the German consortium for hereditary breast and ovarian cancer.

Bick U, Engel C, Krug B, Heindel W, Fallenberg EM, Rhiem K, Maintz D, Golatta M, Speiser D, Rjosk-Dendorfer D, Lämmer-Skarke I, Dietzel F, Schäfer KWF, Leinert E, Weigel S, Sauer S, Pertschy S, Hofmockel T, Hagert-Winkler A, Kast K, Quante A, Meindl A, Kiechle M, Loeffler M, Schmutzler RK; German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC).

Breast Cancer Res Treat. 2019 Feb 6. doi: 10.1007/s10549-019-05152-9. [Epub ahead of print]


Entropy/Enthalpy Compensation in Anion Binding: Biotin[6]uril and Biotin-l-sulfoxide[6]uril Reveal Strong Solvent Dependency.

Andersen NN, Eriksen K, Lisbjerg M, Ottesen ME, Milhøj BO, Sauer SPA, Pittelkow M.

J Org Chem. 2019 Feb 19. doi: 10.1021/acs.joc.8b02797. [Epub ahead of print]


The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer.

Zhu Q, Fang L, Heuberger J, Kranz A, Schipper J, Scheckenbach K, Vidal RO, Sunaga-Franze DY, Müller M, Wulf-Goldenberg A, Sauer S, Birchmeier W.

Cell Rep. 2019 Jan 8;26(2):415-428.e5. doi: 10.1016/j.celrep.2018.12.059.


A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding.

Hernáez B, Alonso-Lobo JM, Montanuy I, Fischer C, Sauer S, Sigal L, Sevilla N, Alcamí A.

Nat Commun. 2018 Dec 21;9(1):5440. doi: 10.1038/s41467-018-07772-z.


RPA(D) and HRPA(D): Two new models for calculations of NMR indirect nuclear spin-spin coupling constants.

Schnack-Petersen AK, Haase PAB, Faber R, Provasi PF, Sauer SPA.

J Comput Chem. 2018 Dec 15;39(32):2647-2666. doi: 10.1002/jcc.25712.


The influence of relativistic effects on nuclear magnetic resonance spin-spin coupling constant polarizabilities of H2 O2 , H2 S2 , H2 Se2 , and H2 Te2.

Pagola GI, Larsen MAB, Ferraro M, Sauer SPA.

J Comput Chem. 2018 Dec 5;39(31):2589-2600. doi: 10.1002/jcc.25648.


Computational Prediction of 1 H and 13 C NMR Chemical Shifts for Protonated Alkylpyrroles: Electron Correlation and Not Solvation is the Salvation.

Lacerda EG Jr, Kamounah FS, Coutinho K, Sauer SPA, Hansen PE, Hammerich O.

Chemphyschem. 2019 Jan 7;20(1):78-91. doi: 10.1002/cphc.201801066. Epub 2018 Dec 7.


Phenotypic characterization and whole genome analysis of extended-spectrum beta-lactamase-producing bacteria isolated from dogs in Germany.

Boehmer T, Vogler AJ, Thomas A, Sauer S, Hergenroether M, Straubinger RK, Birdsell D, Keim P, Sahl JW, Williamson CHD, Riehm JM.

PLoS One. 2018 Oct 26;13(10):e0206252. doi: 10.1371/journal.pone.0206252. eCollection 2018.


Chromatin accessibility dynamics across C. elegans development and ageing.

Jänes J, Dong Y, Schoof M, Serizay J, Appert A, Cerrato C, Woodbury C, Chen R, Gemma C, Huang N, Kissiov D, Stempor P, Steward A, Zeiser E, Sauer S, Ahringer J.

Elife. 2018 Oct 26;7. pii: e37344. doi: 10.7554/eLife.37344.


The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory.

Daniel B, Nagy G, Czimmerer Z, Horvath A, Hammers DW, Cuaranta-Monroy I, Poliska S, Tzerpos P, Kolostyak Z, Hays TT, Patsalos A, Houtman R, Sauer S, Francois-Deleuze J, Rastinejad F, Balint BL, Sweeney HL, Nagy L.

Immunity. 2018 Oct 16;49(4):615-626.e6. doi: 10.1016/j.immuni.2018.09.005.


Direct observation of Mg2+ complexes in ionic liquid solutions by 31Mg β-NMR spectroscopy.

Szunyogh D, McFadden RML, Karner VL, Chatzichristos A, Day Goodacre T, Dehn MH, Formenti L, Fujimoto D, Gottberg A, Kallenberg E, Kálomista I, Kiefl RF, Larsen FH, Lassen J, Levy CDP, Li R, MacFarlane WA, McKenzie I, Morris GD, Pallada S, Pearson MR, Sauer SPA, Schaffer P, Thulstrup PW, Hemmingsen L, Stachura M.

Dalton Trans. 2018 Oct 23;47(41):14431-14435. doi: 10.1039/c8dt02350f.


Local NGF and GDNF levels modulate morphology and function of porcine DRG neurites, In Vitro.

Klusch A, Gorzelanny C, Reeh PW, Schmelz M, Petersen M, Sauer SK.

PLoS One. 2018 Sep 27;13(9):e0203215. doi: 10.1371/journal.pone.0203215. eCollection 2018.


Search for cis-acting factors and maternal effect variants in Silver-Russell patients with ICR1 hypomethylation and their mothers.

Soellner L, Kraft F, Sauer S, Begemann M, Kurth I, Elbracht M, Eggermann T.

Eur J Hum Genet. 2019 Jan;27(1):42-48. doi: 10.1038/s41431-018-0269-1. Epub 2018 Sep 14.


The Effect of Medial Tibial Slope on Anterior Tibial Translation and Short-Term ACL Reconstruction Outcome.

Sauer S, Clatworthy M.

Surg J (N Y). 2018 Sep 10;4(3):e160-e163. doi: 10.1055/s-0038-1669929. eCollection 2018 Jul.


The Ratio of Tibial Slope and Meniscal Bone Angle for the Prediction of ACL Reconstruction Failure Risk.

Sauer S, English R, Clatworthy M.

Surg J (N Y). 2018 Aug 20;4(3):e152-e159. doi: 10.1055/s-0038-1668111. eCollection 2018 Jul.


Development of polarization consistent basis sets for spin-spin coupling constant calculations for the atoms Li, Be, Na, and Mg.

Aggelund PA, Sauer SPA, Jensen F.

J Chem Phys. 2018 Jul 28;149(4):044117. doi: 10.1063/1.5034109.


Transportal central femoral tunnel placement has a significantly higher revision rate than transtibial AM femoral tunnel placement in hamstring ACL reconstruction.

Clatworthy M, Sauer S, Roberts T.

Knee Surg Sports Traumatol Arthrosc. 2018 Jul 12. doi: 10.1007/s00167-018-5036-x. [Epub ahead of print]


HAM-TBS: high-accuracy methylation measurements via targeted bisulfite sequencing.

Roeh S, Wiechmann T, Sauer S, Ködel M, Binder EB, Provençal N.

Epigenetics Chromatin. 2018 Jul 4;11(1):39. doi: 10.1186/s13072-018-0209-x.


A prospective study on serum Cytokeratin (CK)-18 and CK18 fragments as biomarkers of acute hepato-intestinal GVHD.

Sauer S, Hüsing J, Hajda J, Neumann F, Radujkovic A, Ho AD, Dreger P, Luft T.

Leukemia. 2018 Dec;32(12):2685-2692. doi: 10.1038/s41375-018-0183-0. Epub 2018 Jun 27.


Reliability and main findings of the flexible endoscopic evaluation of swallowing-Tensilon test in patients with myasthenia gravis and dysphagia.

Im S, Suntrup-Krueger S, Colbow S, Sauer S, Claus I, Meuth SG, Dziewas R, Warnecke T.

Eur J Neurol. 2018 Oct;25(10):1235-1242. doi: 10.1111/ene.13688. Epub 2018 Jun 22.


Z-dependence of mean excitation energies for second and third row atoms and their ions.

Sauer SPA, Sabin JR, Oddershede J.

J Chem Phys. 2018 May 7;148(17):174307. doi: 10.1063/1.5027708.


A Review of Casualties Transported to Role 2 Medical Treatment Facilities in Afghanistan.

Kotwal RS, Staudt AM, Trevino JD, Valdez-Delgado KK, Le TD, Gurney JM, Sauer SW, Shackelford SA, Stockinger ZT, Mann-Salinas EA.

Mil Med. 2018 Mar 1;183(suppl_1):134-145. doi: 10.1093/milmed/usx211.


Loss of the hematopoietic stem cell factor GATA2 in the osteogenic lineage impairs trabecularization and mechanical strength of bone.

Tolkachov A, Fischer C, Ambrosi TH, Bothe M, Han CT, Muenzner M, Mathia S, Salminen M, Seifert G, Thiele M, Duda GN, Meijsing SH, Sauer S, Schulz TJ, Schupp M.

Mol Cell Biol. 2018 Mar 26. pii: MCB.00599-17. doi: 10.1128/MCB.00599-17. [Epub ahead of print]


The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages.

Daniel B, Nagy G, Horvath A, Czimmerer Z, Cuaranta-Monroy I, Poliska S, Hays TT, Sauer S, Francois-Deleuze J, Nagy L.

Nucleic Acids Res. 2018 May 18;46(9):4425-4439. doi: 10.1093/nar/gky157.


Theoretical study of the NMR chemical shift of Xe in supercritical condition.

Lacerda EG Jr, Sauer SPA, Mikkelsen KV, Coutinho K, Canuto S.

J Mol Model. 2018 Feb 20;24(3):62. doi: 10.1007/s00894-018-3600-4.


Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart.

Jabs M, Rose AJ, Lehmann LH, Taylor J, Moll I, Sijmonsma TP, Herberich SE, Sauer SW, Poschet G, Federico G, Mogler C, Weis EM, Augustin HG, Yan M, Gretz N, Schmid RM, Adams RH, Gröne HJ, Hell R, Okun JG, Backs J, Nawroth PP, Herzig S, Fischer A.

Circulation. 2018 Jun 12;137(24):2592-2608. doi: 10.1161/CIRCULATIONAHA.117.029733. Epub 2018 Jan 20.


The bioequivalence of a single intravenous administration of the anesthetic alfaxalone in cyclodextrin versus alfaxalone in cyclodextrin plus preservatives in cats.

Pasloske K, Ranasinghe MG, Sauer S, Hare J.

J Vet Pharmacol Ther. 2018 Jun;41(3):437-446. doi: 10.1111/jvp.12485. Epub 2018 Jan 19.


The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages.

Czimmerer Z, Daniel B, Horvath A, Rückerl D, Nagy G, Kiss M, Peloquin M, Budai MM, Cuaranta-Monroy I, Simandi Z, Steiner L, Nagy B Jr, Poliska S, Banko C, Bacso Z, Schulman IG, Sauer S, Deleuze JF, Allen JE, Benko S, Nagy L.

Immunity. 2018 Jan 16;48(1):75-90.e6. doi: 10.1016/j.immuni.2017.12.010.


Perturbation-response genes reveal signaling footprints in cancer gene expression.

Schubert M, Klinger B, Klünemann M, Sieber A, Uhlitz F, Sauer S, Garnett MJ, Blüthgen N, Saez-Rodriguez J.

Nat Commun. 2018 Jan 2;9(1):20. doi: 10.1038/s41467-017-02391-6.


A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway.

Lehmann LH, Jebessa ZH, Kreusser MM, Horsch A, He T, Kronlage M, Dewenter M, Sramek V, Oehl U, Krebs-Haupenthal J, von der Lieth AH, Schmidt A, Sun Q, Ritterhoff J, Finke D, Völkers M, Jungmann A, Sauer SW, Thiel C, Nickel A, Kohlhaas M, Schäfer M, Sticht C, Maack C, Gretz N, Wagner M, El-Armouche A, Maier LS, Londoño JEC, Meder B, Freichel M, Gröne HJ, Most P, Müller OJ, Herzig S, Furlong EEM, Katus HA, Backs J.

Nat Med. 2018 Jan;24(1):62-72. doi: 10.1038/nm.4452. Epub 2017 Dec 11.


De novo mutations implicate novel genes in systemic lupus erythematosus.

Pullabhatla V, Roberts AL, Lewis MJ, Mauro D, Morris DL, Odhams CA, Tombleson P, Liljedahl U, Vyse S, Simpson MA, Sauer S, de Rinaldis E, Syvänen AC, Vyse TJ.

Hum Mol Genet. 2018 Feb 1;27(3):421-429. doi: 10.1093/hmg/ddx407.


Impairment of astrocytic glutaminolysis in glutaric aciduria type I.

Komatsuzaki S, Ediga RD, Okun JG, Kölker S, Sauer SW.

J Inherit Metab Dis. 2018 Jan;41(1):91-99. doi: 10.1007/s10545-017-0096-5. Epub 2017 Nov 2.


Relativistic DFT Calculations of Hyperfine Coupling Constants in 5d Hexafluorido Complexes: [ReF6 ]2- and [IrF6 ]2.

Haase PAB, Repisky M, Komorovsky S, Bendix J, Sauer SPA.

Chemistry. 2018 Apr 6;24(20):5124-5133. doi: 10.1002/chem.201704653. Epub 2017 Dec 4.


Pharmacological targeting of GLI1 inhibits proliferation, tumor emboli formation and in vivo tumor growth of inflammatory breast cancer cells.

Oladapo HO, Tarpley M, Sauer SJ, Addo KA, Ingram SM, Strepay D, Ehe BK, Chdid L, Trinkler M, Roques JR, Darr DB, Fleming JM, Devi GR, Williams KP.

Cancer Lett. 2017 Dec 28;411:136-149. doi: 10.1016/j.canlet.2017.09.033. Epub 2017 Sep 28.


Molecular Switching in Confined Spaces: Effects of Encapsulating the DHA/VHF Photo-Switch in Cucurbiturils.

Petersen MÅ, Rasmussen B, Andersen NN, Sauer SPA, Nielsen MB, Beeren SR, Pittelkow M.

Chemistry. 2017 Dec 1;23(67):17010-17016. doi: 10.1002/chem.201703196. Epub 2017 Sep 18.


Photosensitization of TRPA1 and TRPV1 by 7-dehydrocholesterol: implications for the Smith-Lemli-Opitz syndrome.

Babes A, Ciotu CI, Hoffmann T, Kichko TI, Selescu T, Neacsu C, Sauer SK, Reeh PW, Fischer MJM.

Pain. 2017 Dec;158(12):2475-2486. doi: 10.1097/j.pain.0000000000001056.


CYP24A1 Mutation in a Girl Infant with Idiopathic Infantile Hypercalcemia.

Madsen JOB, Sauer S, Beck B, Johannesen J.

J Clin Res Pediatr Endocrinol. 2018 Mar 1;10(1):83-86. doi: 10.4274/jcrpe.4841. Epub 2017 Sep 6.


Observation oriented modeling revised from a statistical point of view.

Sauer S.

Behav Res Methods. 2018 Aug;50(4):1749-1761. doi: 10.3758/s13428-017-0949-8.


Bone Tunnel Enlargement after ACL Reconstruction with Hamstring Autograft Is Dependent on Original Bone Tunnel Diameter.

Sauer S, Lind M.

Surg J (N Y). 2017 Jun 19;3(2):e96-e100. doi: 10.1055/s-0037-1603950. eCollection 2017 Apr.


Intramedullary Screw Fixation of a Proximal Fifth Metatarsal Stress Fracture in an Elite Athlete: A Case Report.

Sauer S.

Surg J (N Y). 2017 Mar 17;3(1):e6-e8. doi: 10.1055/s-0037-1599833. eCollection 2017 Jan.


Polylox barcoding reveals haematopoietic stem cell fates realized in vivo.

Pei W, Feyerabend TB, Rössler J, Wang X, Postrach D, Busch K, Rode I, Klapproth K, Dietlein N, Quedenau C, Chen W, Sauer S, Wolf S, Höfer T, Rodewald HR.

Nature. 2017 Aug 24;548(7668):456-460. doi: 10.1038/nature23653. Epub 2017 Aug 16.


RXR heterodimers orchestrate transcriptional control of neurogenesis and cell fate specification.

Simandi Z, Horvath A, Cuaranta-Monroy I, Sauer S, Deleuze JF, Nagy L.

Mol Cell Endocrinol. 2018 Aug 15;471:51-62. doi: 10.1016/j.mce.2017.07.033. Epub 2017 Aug 2.


Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages.

Czimmerer Z, Nagy ZS, Nagy G, Horvath A, Silye-Cseh T, Kriston A, Jonas D, Sauer S, Steiner L, Daniel B, Deleuze JF, Nagy L.

Mol Cell Endocrinol. 2018 Aug 15;471:63-74. doi: 10.1016/j.mce.2017.07.034. Epub 2017 Jul 31.


Faecal microbiota composition associates with abdominal pain in the general population.

Hadizadeh F, Bonfiglio F, Belheouane M, Vallier M, Sauer S, Bang C, Bujanda L, Andreasson A, Agreus L, Engstrand L, Talley NJ, Rafter J, Baines JF, Walter S, Franke A, D'Amato M.

Gut. 2018 Apr;67(4):778-779. doi: 10.1136/gutjnl-2017-314792. Epub 2017 Aug 1. No abstract available.


Prediction of outcome in internet-delivered cognitive behaviour therapy for paediatric obsessive-compulsive disorder: A machine learning approach.

Lenhard F, Sauer S, Andersson E, Månsson KN, Mataix-Cols D, Rück C, Serlachius E.

Int J Methods Psychiatr Res. 2018 Mar;27(1). doi: 10.1002/mpr.1576. Epub 2017 Jul 28.


Cellular citrate levels establish a regulatory link between energy metabolism and the hepatic iron hormone hepcidin.

da Silva AR, Neves J, Mleczko-Sanecka K, Tandon A, Sauer SW, Hentze MW, Muckenthaler MU.

J Mol Med (Berl). 2017 Aug;95(8):851-860. doi: 10.1007/s00109-017-1551-3. Epub 2017 Jun 5.


Elevated glutaric acid levels in Dhtkd1-/Gcdh- double knockout mice challenge our current understanding of lysine metabolism.

Biagosch C, Ediga RD, Hensler SV, Faerberboeck M, Kuehn R, Wurst W, Meitinger T, Kölker S, Sauer S, Prokisch H.

Biochim Biophys Acta Mol Basis Dis. 2017 Sep;1863(9):2220-2228. doi: 10.1016/j.bbadis.2017.05.018. Epub 2017 May 22.


Inflammatory breast cancer tumor emboli express high levels of anti-apoptotic proteins: use of a quantitative high content and high-throughput 3D IBC spheroid assay to identify targeting strategies.

Arora J, Sauer SJ, Tarpley M, Vermeulen P, Rypens C, Van Laere S, Williams KP, Devi GR, Dewhirst MW.

Oncotarget. 2017 Apr 18;8(16):25848-25863. doi: 10.18632/oncotarget.15667.

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