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Items: 1 to 50 of 977

1.

Osteoarticular infections: a specific program for older patients?

Uçkay I, Holy D, Betz M, Sauer R, Huber T, Burkhard J.

Aging Clin Exp Res. 2019 Sep 7. doi: 10.1007/s40520-019-01329-w. [Epub ahead of print] Review.

PMID:
31494913
2.

Radiotherapy after skin-sparing mastectomy with immediate breast reconstruction in intermediate-risk breast cancer : Indication and technical considerations.

Hehr T, Baumann R, Budach W, Duma MN, Dunst J, Feyer P, Fietkau R, Haase W, Harms W, Krug D, Piroth MD, Sedlmayer F, Souchon R, Wenz F, Sauer R; Breast Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO).

Strahlenther Onkol. 2019 Nov;195(11):949-963. doi: 10.1007/s00066-019-01507-9. Epub 2019 Aug 26.

PMID:
31451835
3.

Heart-sparing radiotherapy techniques in breast cancer patients: a recommendation of the breast cancer expert panel of the German society of radiation oncology (DEGRO).

Duma MN, Baumann R, Budach W, Dunst J, Feyer P, Fietkau R, Haase W, Harms W, Hehr T, Krug D, Piroth MD, Sedlmayer F, Souchon R, Sauer R; Breast Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO).

Strahlenther Onkol. 2019 Oct;195(10):861-871. doi: 10.1007/s00066-019-01495-w. Epub 2019 Jul 18.

PMID:
31321461
4.

Interactions between a subset of substrate side chains and AAA+ motor pore loops determine grip during protein unfolding.

Bell TA, Baker TA, Sauer RT.

Elife. 2019 Jun 28;8. pii: e46808. doi: 10.7554/eLife.46808.

5.

Grantsmanship writing tips: the experimental design.

Gabbi C, Sauer RM.

Eur J Intern Med. 2019 Jun;64:21-23. doi: 10.1016/j.ejim.2019.02.003. Epub 2019 Feb 26. No abstract available.

PMID:
30819603
6.

Grantsmanship writing tips: significance, innovation and impact.

Sauer RM, Gabbi C.

Eur J Intern Med. 2019 Jul;65:26-28. doi: 10.1016/j.ejim.2019.02.004. Epub 2019 Feb 23. No abstract available.

PMID:
30803834
7.

Grantsmanship writing tips: background, hypothesis and aims.

Gabbi C, Sauer RM.

Eur J Intern Med. 2019 Mar;61:25-28. doi: 10.1016/j.ejim.2019.02.002. Epub 2019 Feb 16. No abstract available.

PMID:
30777596
8.

Roles of the ClpX IGF loops in ClpP association, dissociation, and protein degradation.

Amor AJ, Schmitz KR, Baker TA, Sauer RT.

Protein Sci. 2019 Apr;28(4):756-765. doi: 10.1002/pro.3590. Epub 2019 Mar 4.

PMID:
30767302
9.

A mutagenesis screen for essential plastid biogenesis genes in human malaria parasites.

Tang Y, Meister TR, Walczak M, Pulkoski-Gross MJ, Hari SB, Sauer RT, Amberg-Johnson K, Yeh E.

PLoS Biol. 2019 Feb 6;17(2):e3000136. doi: 10.1371/journal.pbio.3000136. eCollection 2019 Feb.

10.

Tissue plasminogen activator and neuropathy open the blood-nerve barrier with upregulation of microRNA-155-5p in male rats.

Reinhold AK, Yang S, Chen JT, Hu L, Sauer RS, Krug SM, Mambretti EM, Fromm M, Brack A, Rittner HL.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1160-1169. doi: 10.1016/j.bbadis.2019.01.008. Epub 2019 Jan 6.

PMID:
30625382
11.

Hinge-Linker Elements in the AAA+ Protein Unfoldase ClpX Mediate Intersubunit Communication, Assembly, and Mechanical Activity.

Bell TA, Baker TA, Sauer RT.

Biochemistry. 2018 Dec 11;57(49):6787-6796. doi: 10.1021/acs.biochem.8b00907. Epub 2018 Nov 20.

PMID:
30418765
12.

Grantsmanship: What? Who? How?

Sauer RM, Gabbi C.

Eur J Intern Med. 2018 Nov;57:22-24. doi: 10.1016/j.ejim.2018.10.006. Epub 2018 Nov 2. No abstract available.

PMID:
30396589
13.

Heart toxicity from breast cancer radiotherapy : Current findings, assessment, and prevention.

Piroth MD, Baumann R, Budach W, Dunst J, Feyer P, Fietkau R, Haase W, Harms W, Hehr T, Krug D, Röser A, Sedlmayer F, Souchon R, Wenz F, Sauer R.

Strahlenther Onkol. 2019 Jan;195(1):1-12. doi: 10.1007/s00066-018-1378-z. Epub 2018 Oct 11. Review.

14.

Structural and Functional Analysis of E. coli Cyclopropane Fatty Acid Synthase.

Hari SB, Grant RA, Sauer RT.

Structure. 2018 Sep 4;26(9):1251-1258.e3. doi: 10.1016/j.str.2018.06.008. Epub 2018 Jul 26.

15.

Neoadjuvant chemotherapy for breast cancer-background for the indication of locoregional treatment.

Krug D, Baumann R, Budach W, Dunst J, Feyer P, Fietkau R, Haase W, Harms W, Hehr T, Piroth MD, Sedlmayer F, Souchon R, Wenz F, Sauer R; Breast Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO).

Strahlenther Onkol. 2018 Sep;194(9):797-805. doi: 10.1007/s00066-018-1329-8. Epub 2018 Jul 4. Review.

PMID:
29974132
16.

Can clinicopathological parameters predict for lymph node metastases in ypT0-2 rectal carcinoma? Results of the CAO/ARO/AIO-94 and CAO/ARO/AIO-04 phase 3 trials.

von den Grün JM, Hartmann A, Fietkau R, Ghadimi M, Liersch T, Hohenberger W, Weitz J, Sauer R, Wittekind C, Ströbel P, Rödel C, Fokas E; German Rectal Cancer Study Group.

Radiother Oncol. 2018 Sep;128(3):557-563. doi: 10.1016/j.radonc.2018.06.008. Epub 2018 Jun 18.

PMID:
29929861
17.

Association of Plane of Total Mesorectal Excision With Prognosis of Rectal Cancer: Secondary Analysis of the CAO/ARO/AIO-04 Phase 3 Randomized Clinical Trial.

Kitz J, Fokas E, Beissbarth T, Ströbel P, Wittekind C, Hartmann A, Rüschoff J, Papadopoulos T, Rösler E, Ortloff-Kittredge P, Kania U, Schlitt H, Link KH, Bechstein W, Raab HR, Staib L, Germer CT, Liersch T, Sauer R, Rödel C, Ghadimi M, Hohenberger W; German Rectal Cancer Study Group.

JAMA Surg. 2018 Aug 1;153(8):e181607. doi: 10.1001/jamasurg.2018.1607. Epub 2018 Aug 15.

18.

Impact of age on the efficacy of oxaliplatin in the preoperative chemoradiotherapy and adjuvant chemotherapy of rectal cancer: a post hoc analysis of the CAO/ARO/AIO-04 phase III trial.

Hofheinz RD, Arnold D, Fokas E, Kaufmann M, Hothorn T, Folprecht G, Fietkau R, Hohenberger W, Ghadimi M, Liersch T, Grabenbauer GG, Sauer R, Rödel C, Graeven U; German Rectal Cancer Study Group.

Ann Oncol. 2018 Aug 1;29(8):1793-1799. doi: 10.1093/annonc/mdy205.

PMID:
29873684
19.

Long-term prognostic impact of surgical complications in the German Rectal Cancer Trial CAO/ARO/AIO-94.

Sprenger T, Beißbarth T, Sauer R, Tschmelitsch J, Fietkau R, Liersch T, Hohenberger W, Staib L, Gaedcke J, Raab HR, Rödel C, Ghadimi M.

Br J Surg. 2018 Oct;105(11):1510-1518. doi: 10.1002/bjs.10877. Epub 2018 May 30.

PMID:
29846017
20.

Health status in patients with COPD treated with roflumilast: two large noninterventional real-life studies: DINO and DACOTA.

Kardos P, Mokros I, Sauer R, Vogelmeier CF.

Int J Chron Obstruct Pulmon Dis. 2018 May 3;13:1455-1468. doi: 10.2147/COPD.S159827. eCollection 2018.

21.

Neoadjuvant rectal score as individual-level surrogate for disease-free survival in rectal cancer in the CAO/ARO/AIO-04 randomized phase III trial.

Fokas E, Fietkau R, Hartmann A, Hohenberger W, Grützmann R, Ghadimi M, Liersch T, Ströbel P, Grabenbauer GG, Graeven U, Hofheinz RD, Köhne CH, Wittekind C, Sauer R, Kaufmann M, Hothorn T, Rödel C; German Rectal Cancer Study Group.

Ann Oncol. 2018 Jul 1;29(7):1521-1527. doi: 10.1093/annonc/mdy143.

PMID:
29718095
22.

Structure of the Mitochondrial Aminolevulinic Acid Synthase, a Key Heme Biosynthetic Enzyme.

Brown BL, Kardon JR, Sauer RT, Baker TA.

Structure. 2018 Apr 3;26(4):580-589.e4. doi: 10.1016/j.str.2018.02.012. Epub 2018 Mar 15.

23.

Mechanical Protein Unfolding and Degradation.

Olivares AO, Baker TA, Sauer RT.

Annu Rev Physiol. 2018 Feb 10;80:413-429. doi: 10.1146/annurev-physiol-021317-121303. Review.

PMID:
29433415
24.

Individualization of post-mastectomy radiotherapy and regional nodal irradiation based on treatment response after neoadjuvant chemotherapy for breast cancer : A systematic review.

Krug D, Baumann R, Budach W, Dunst J, Feyer P, Fietkau R, Haase W, Harms W, Hehr T, Piroth MD, Sedlmayer F, Souchon R, Wenz F, Sauer R.

Strahlenther Onkol. 2018 Jul;194(7):607-618. doi: 10.1007/s00066-018-1270-x. Epub 2018 Jan 30. Review.

PMID:
29383405
25.

Irreversible thermodynamics of curved lipid membranes.

Sahu A, Sauer RA, Mandadapu KK.

Phys Rev E. 2017 Oct;96(4-1):042409. doi: 10.1103/PhysRevE.96.042409. Epub 2017 Oct 17.

PMID:
29347561
26.

Tumor Regression Grading After Preoperative Chemoradiotherapy as a Prognostic Factor and Individual-Level Surrogate for Disease-Free Survival in Rectal Cancer.

Fokas E, Ströbel P, Fietkau R, Ghadimi M, Liersch T, Grabenbauer GG, Hartmann A, Kaufmann M, Sauer R, Graeven U, Hoffmanns H, Raab HR, Hothorn T, Wittekind C, Rödel C; German Rectal Cancer Study Group.

J Natl Cancer Inst. 2017 Dec 1;109(12). doi: 10.1093/jnci/djx095.

PMID:
29206996
27.

Zum Tod unseres Ehrenmitglieds, Prof. Seymour Levitt MD.

Sauer R.

Strahlenther Onkol. 2017 Dec;193(12):1079-1080. doi: 10.1007/s00066-017-1237-3. German. No abstract available.

PMID:
29127436
28.

[COPD-Management, a comprehensive review].

Gillissen A, Kähler CM, Koczulla AR, Sauer R, Paparoupa M.

MMW Fortschr Med. 2017 Nov;159(Suppl 3):32-43. doi: 10.1007/s15006-017-9594-5. German. No abstract available.

PMID:
29086259
29.

Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens.

Amberg-Johnson K, Hari SB, Ganesan SM, Lorenzi HA, Sauer RT, Niles JC, Yeh E.

Elife. 2017 Aug 18;6. pii: e29865. doi: 10.7554/eLife.29865.

30.

[Lymphocytic myocarditis in a patient with metastatic clear cell renal cell carcinoma treated with Nivolumab].

Sauer R, Kiewe P, Desole M, Schuler M, Theissig F, Roth A, Mairinger T.

Pathologe. 2017 Nov;38(6):535-539. doi: 10.1007/s00292-017-0349-y. German.

PMID:
28819833
31.

Blood-spinal cord barrier breakdown and pericyte deficiency in peripheral neuropathy.

Sauer RS, Kirchner J, Yang S, Hu L, Leinders M, Sommer C, Brack A, Rittner HL.

Ann N Y Acad Sci. 2017 Oct;1405(1):71-88. doi: 10.1111/nyas.13436. Epub 2017 Jul 28.

PMID:
28753236
32.

Effect of directional pulling on mechanical protein degradation by ATP-dependent proteolytic machines.

Olivares AO, Kotamarthi HC, Stein BJ, Sauer RT, Baker TA.

Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):E6306-E6313. doi: 10.1073/pnas.1707794114. Epub 2017 Jul 19.

33.

Inflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation.

Oehler B, Kistner K, Martin C, Schiller J, Mayer R, Mohammadi M, Sauer RS, Filipovic MR, Nieto FR, Kloka J, Pflücke D, Hill K, Schaefer M, Malcangio M, Reeh PW, Brack A, Blum R, Rittner HL.

Sci Rep. 2017 Jul 14;7(1):5447. doi: 10.1038/s41598-017-05348-3.

34.

[COPD, an update of current management recommendations].

Gillissen A, Kähler CM, Koczulla AR, Sauer R.

MMW Fortschr Med. 2017 Jun;159(12):56-59. doi: 10.1007/s15006-017-9851-7. Review. German. No abstract available.

PMID:
28656404
35.

Efficient isogeometric thin shell formulations for soft biological materials.

Roohbakhshan F, Sauer RA.

Biomech Model Mechanobiol. 2017 Oct;16(5):1569-1597. doi: 10.1007/s10237-017-0906-6. Epub 2017 Apr 12.

PMID:
28405768
36.

Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia diagnosed by transbronchial lung cryobiopsy: a case report.

Sauer R, Griff S, Blau A, Franke A, Mairinger T, Grah C.

J Med Case Rep. 2017 Apr 7;11(1):95. doi: 10.1186/s13256-017-1254-y.

37.

Good outcome of brain stem progressive multifocal leukoencephalopathy in an immunosuppressed renal transplant patient: Importance of early detection and rapid immune reconstitution.

Sauer R, Gölitz P, Jacobi J, Schwab S, Linker RA, Lee DH.

J Neurol Sci. 2017 Apr 15;375:76-79. doi: 10.1016/j.jns.2017.01.046. Epub 2017 Jan 14.

PMID:
28320193
38.

Covalently linked HslU hexamers support a probabilistic mechanism that links ATP hydrolysis to protein unfolding and translocation.

Baytshtok V, Chen J, Glynn SE, Nager AR, Grant RA, Baker TA, Sauer RT.

J Biol Chem. 2017 Apr 7;292(14):5695-5704. doi: 10.1074/jbc.M116.768978. Epub 2017 Feb 21.

39.

Rational Design of Selective and Bioactive Inhibitors of the Mycobacterium tuberculosis Proteasome.

Totaro KA, Barthelme D, Simpson PT, Jiang X, Lin G, Nathan CF, Sauer RT, Sello JK.

ACS Infect Dis. 2017 Feb 10;3(2):176-181. doi: 10.1021/acsinfecdis.6b00172. Epub 2016 Dec 5.

40.

Current controversies in radiotherapy for breast cancer.

Krug D, Baumann R, Budach W, Dunst J, Feyer P, Fietkau R, Haase W, Harms W, Piroth MD, Sautter-Bihl ML, Sedlmayer F, Souchon R, Wenz F, Sauer R; Breast cancer expert panel of the German Society of Radiation Oncology (DEGRO).

Radiat Oncol. 2017 Jan 23;12(1):25. doi: 10.1186/s13014-017-0766-3. Review.

41.

A Novel Approach for the Control of Inflammatory Pain: Prostaglandin E2 Complexation by Randomly Methylated β-Cyclodextrins.

Sauer RS, Rittner HL, Roewer N, Sohajda T, Shityakov S, Brack A, Broscheit JA.

Anesth Analg. 2017 Feb;124(2):675-685. doi: 10.1213/ANE.0000000000001674.

PMID:
27930390
42.

Lower hypoxic ventilatory response in smokers compared to non-smokers during abstinence from cigarettes.

Hildebrandt W, Sauer R, Koehler U, Bärtsch P, Kinscherf R.

BMC Pulm Med. 2016 Nov 24;16(1):159.

43.

The AAA+ FtsH Protease Degrades an ssrA-Tagged Model Protein in the Inner Membrane of Escherichia coli.

Hari SB, Sauer RT.

Biochemistry. 2016 Oct 11;55(40):5649-5652. Epub 2016 Sep 30.

44.

A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis.

Baytshtok V, Fei X, Grant RA, Baker TA, Sauer RT.

Structure. 2016 Oct 4;24(10):1766-1777. doi: 10.1016/j.str.2016.08.012. Epub 2016 Sep 22.

45.

"Watchful Waiting" als Alternative zur Rektumexstirpation nach kompletter Tumorremission infolge neoadjuvant intendierter Radiochemotherapie?

Hohenberger W, Sauer R.

Strahlenther Onkol. 2016 Sep;192(9):677-8. doi: 10.1007/s00066-016-1018-4. German. No abstract available.

PMID:
27406137
46.

Intra-patient comparison of parietal pleural biopsies by rigid forceps, flexible forceps and cryoprobe obtained during medical thoracoscopy: a prospective series of 80 cases with pleural effusion.

Wurps H, Schönfeld N, Bauer TT, Bock M, Duve C, Sauer R, Mairinger T, Griff S.

BMC Pulm Med. 2016 Jul 7;16(1):98. doi: 10.1186/s12890-016-0258-5.

47.

Impact of tiotropium + olodaterol on physical functioning in COPD: results of an open-label observational study.

Sauer R, Hänsel M, Buhl R, Rubin RA, Frey M, Glaab T.

Int J Chron Obstruct Pulmon Dis. 2016 Apr 27;11:891-8. doi: 10.2147/COPD.S103023. eCollection 2016.

48.

Stage-Dependent Frequency of Lymph Node Metastases in Patients With Rectal Carcinoma After Preoperative Chemoradiation: Results from the CAO/ARO/AIO-94 Trial and From a Comparative Prospective Evaluation With Extensive Pathological Workup.

Sprenger T, Rothe H, Conradi LC, Beissbarth T, Kauffels A, Kitz J, Homayounfar K, Wolff H, Ströbel P, Ghadimi M, Wittekind C, Sauer R, Rödel C, Liersch T.

Dis Colon Rectum. 2016 May;59(5):377-85. doi: 10.1097/DCR.0000000000000570.

PMID:
27050599
49.

Highly Dynamic Interactions Maintain Kinetic Stability of the ClpXP Protease During the ATP-Fueled Mechanical Cycle.

Amor AJ, Schmitz KR, Sello JK, Baker TA, Sauer RT.

ACS Chem Biol. 2016 Jun 17;11(6):1552-1560. doi: 10.1021/acschembio.6b00083. Epub 2016 Mar 30.

50.

DEGRO practical guidelines for radiotherapy of breast cancer VI: therapy of locoregional breast cancer recurrences.

Harms W, Budach W, Dunst J, Feyer P, Fietkau R, Haase W, Krug D, Piroth MD, Sautter-Bihl ML, Sedlmayer F, Souchon R, Wenz F, Sauer R; Breast Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO).

Strahlenther Onkol. 2016 Apr;192(4):199-208. doi: 10.1007/s00066-015-0939-7. Epub 2016 Mar 1.

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