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Items: 40

1.

MicroRNA-4719 and microRNA-6756-5p Correlate with Castration-Resistant Prostate Cancer Progression through Interleukin-24 Regulation.

Das DK, Persaud L, Sauane M.

Noncoding RNA. 2019 Jan 21;5(1). pii: E10. doi: 10.3390/ncrna5010010.

2.

A Self-degradable Curcumin Polymer with Anti-cancer Activity.

O'Connor NA, Einbond LS, Redenti S, Sauane M, Jitianu A.

J Appl Polym Sci. 2018 Dec 15;135(47). pii: 46867. doi: 10.1002/app.46867. Epub 2018 Aug 27.

PMID:
30555179
3.

IL-24 Promotes Apoptosis through cAMP-Dependent PKA Pathways in Human Breast Cancer Cells.

Persaud L, Mighty J, Zhong X, Francis A, Mendez M, Muharam H, Redenti SM, Das D, Aktas BH, Sauane M.

Int J Mol Sci. 2018 Nov 12;19(11). pii: E3561. doi: 10.3390/ijms19113561.

4.

Eukaryotic Translation Initiation Factor 4A Down-Regulation Mediates Interleukin-24-Induced Apoptosis through Inhibition of Translation.

Zhong X, Persaud L, Muharam H, Francis A, Das D, Aktas BH, Sauane M.

Cancers (Basel). 2018 May 22;10(5). pii: E153. doi: 10.3390/cancers10050153.

5.

Translation Control by p53.

Kasteri J, Das D, Zhong X, Persaud L, Francis A, Muharam H, Sauane M.

Cancers (Basel). 2018 May 5;10(5). pii: E133. doi: 10.3390/cancers10050133.

6.

eIF2α Phosphorylation Mediates IL24-Induced Apoptosis through Inhibition of Translation.

Persaud L, Zhong X, Alvarado G, Do W, Dejoie J, Zybtseva A, Aktas BH, Sauane M.

Mol Cancer Res. 2017 Aug;15(8):1117-1124. doi: 10.1158/1541-7786.MCR-16-0454. Epub 2017 May 1.

7.

Mechanism of Action and Applications of Interleukin 24 in Immunotherapy.

Persaud L, De Jesus D, Brannigan O, Richiez-Paredes M, Huaman J, Alvarado G, Riker L, Mendez G, Dejoie J, Sauane M.

Int J Mol Sci. 2016 Jun 2;17(6). pii: E869. doi: 10.3390/ijms17060869. Review.

8.

Predicted molecular signaling guiding photoreceptor cell migration following transplantation into damaged retina.

Unachukwu UJ, Warren A, Li Z, Mishra S, Zhou J, Sauane M, Lim H, Vazquez M, Redenti S.

Sci Rep. 2016 Mar 3;6:22392. doi: 10.1038/srep22392.

9.

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) activates caspases in human prostate cancer cells through sigma 1 receptor.

Das D, Persaud L, Dejoie J, Happy M, Brannigan O, De Jesus D, Sauane M.

Biochem Biophys Res Commun. 2016 Feb 5;470(2):319-323. doi: 10.1016/j.bbrc.2016.01.055. Epub 2016 Jan 12.

PMID:
26792723
10.

Sigma 1 Receptor antagonist potentiates the anti-cancer effect of p53 by regulating ER stress, ROS production, Bax levels, and caspase-3 activation.

Happy M, Dejoie J, Zajac CK, Cortez B, Chakraborty K, Aderemi J, Sauane M.

Biochem Biophys Res Commun. 2015 Jan 9;456(2):683-8. doi: 10.1016/j.bbrc.2014.12.029. Epub 2014 Dec 13.

PMID:
25511708
11.

Microfluidic generated EGF-gradients induce chemokinesis of transplantable retinal progenitor cells via the JAK/STAT and PI3kinase signaling pathways.

Unachukwu UJ, Sauane M, Vazquez M, Redenti S.

PLoS One. 2013 Dec 23;8(12):e83906. doi: 10.1371/journal.pone.0083906. eCollection 2013. Erratum in: PLoS One. 2014;9(1). 10.1371/annotation/ec7d8834-50c9-4e2c-b22e-5b73e8b1377c.

12.

Sigma 1 Receptor plays a prominent role in IL-24-induced cancer-specific apoptosis.

Do W, Herrera C, Mighty J, Shumskaya M, Redenti SM, Sauane M.

Biochem Biophys Res Commun. 2013 Sep 20;439(2):215-20. doi: 10.1016/j.bbrc.2013.08.057. Epub 2013 Aug 26.

PMID:
23988449
13.

The development of MDA-7/IL-24 as a cancer therapeutic.

Dent P, Yacoub A, Hamed HA, Park MA, Dash R, Bhutia SK, Sarkar D, Wang XY, Gupta P, Emdad L, Lebedeva IV, Sauane M, Su ZZ, Rahmani M, Broaddus WC, Young HF, Lesniak MS, Grant S, Curiel DT, Fisher PB.

Pharmacol Ther. 2010 Nov;128(2):375-84. doi: 10.1016/j.pharmthera.2010.08.001. Epub 2010 Aug 21. Review.

14.

MDA-7/IL-24 as a cancer therapeutic: from bench to bedside.

Dent P, Yacoub A, Hamed HA, Park MA, Dash R, Bhutia SK, Sarkar D, Gupta P, Emdad L, Lebedeva IV, Sauane M, Su ZZ, Rahmani M, Broaddus WC, Young HF, Lesniak M, Grant S, Curiel DT, Fisher PB.

Anticancer Drugs. 2010 Sep;21(8):725-31. doi: 10.1097/CAD.0b013e32833cfbe1. Review.

15.

Ceramide plays a prominent role in MDA-7/IL-24-induced cancer-specific apoptosis.

Sauane M, Su ZZ, Dash R, Liu X, Norris JS, Sarkar D, Lee SG, Allegood JC, Dent P, Spiegel S, Fisher PB.

J Cell Physiol. 2010 Mar;222(3):546-55. doi: 10.1002/jcp.21969.

PMID:
19937735
16.

Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24.

Emdad L, Lebedeva IV, Su ZZ, Gupta P, Sauane M, Dash R, Grant S, Dent P, Curiel DT, Sarkar D, Fisher PB.

Cancer Biol Ther. 2009 Mar;8(5):391-400. Epub 2009 Mar 8. Review.

PMID:
19276652
17.

Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis.

Sauane M, Su ZZ, Gupta P, Lebedeva IV, Dent P, Sarkar D, Fisher PB.

Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9763-8. doi: 10.1073/pnas.0804089105. Epub 2008 Jul 3.

18.

Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells.

Yacoub A, Park MA, Gupta P, Rahmani M, Zhang G, Hamed H, Hanna D, Sarkar D, Lebedeva IV, Emdad L, Sauane M, Vozhilla N, Spiegel S, Koumenis C, Graf M, Curiel DT, Grant S, Fisher PB, Dent P.

Mol Cancer Ther. 2008 Feb;7(2):297-313. doi: 10.1158/1535-7163.MCT-07-2166.

19.

mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review).

Lebedeva IV, Emdad L, Su ZZ, Gupta P, Sauane M, Sarkar D, Staudt MR, Liu SJ, Taher MM, Xiao R, Barral P, Lee SG, Wang D, Vozhilla N, Park ES, Chatman L, Boukerche H, Ramesh R, Inoue S, Chada S, Li R, De Pass AL, Mahasreshti PJ, Dmitriev IP, Curiel DT, Yacoub A, Grant S, Dent P, Senzer N, Nemunaitis JJ, Fisher PB.

Int J Oncol. 2007 Nov;31(5):985-1007. Review.

PMID:
17912425
20.

Melanoma differentiation associated gene-7 (mda-7)/IL-24: a 'magic bullet' for cancer therapy?

Sarkar D, Lebedeva IV, Gupta P, Emdad L, Sauane M, Dent P, Curiel DT, Fisher PB.

Expert Opin Biol Ther. 2007 May;7(5):577-86. Review.

PMID:
17477796
21.
22.

Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): novel gene therapeutic for metastatic melanoma.

Fisher PB, Sarkar D, Lebedeva IV, Emdad L, Gupta P, Sauane M, Su ZZ, Grant S, Dent P, Curiel DT, Senzer N, Nemunaitis J.

Toxicol Appl Pharmacol. 2007 Nov 1;224(3):300-7. Epub 2006 Nov 23. Review.

23.

N-glycosylation of MDA-7/IL-24 is dispensable for tumor cell-specific apoptosis and "bystander" antitumor activity.

Sauane M, Gupta P, Lebedeva IV, Su ZZ, Sarkar D, Randolph A, Valerie K, Gopalkrishnan RV, Fisher PB.

Cancer Res. 2006 Dec 15;66(24):11869-77.

24.

mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine.

Gupta P, Su ZZ, Lebedeva IV, Sarkar D, Sauane M, Emdad L, Bachelor MA, Grant S, Curiel DT, Dent P, Fisher PB.

Pharmacol Ther. 2006 Sep;111(3):596-628. Epub 2006 Feb 7. Review.

25.

Leukemia inhibitory factor induces DNA synthesis in Swiss mouse 3T3 cells independently of cyclin D1 expression through a mechanism involving MEK/ERK1/2 activation.

Dekanty A, Sauane M, Cadenas B, Coluccio F, Barrio M, Casala J, Paciencia M, Rogers F, Coso OA, Piwien-Pilipuk G, Rudland PS, de Asúa LJ.

J Biol Chem. 2006 Mar 10;281(10):6136-43. Epub 2005 Nov 15.

26.

Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells.

Su Z, Emdad L, Sauane M, Lebedeva IV, Sarkar D, Gupta P, James CD, Randolph A, Valerie K, Walter MR, Dent P, Fisher PB.

Oncogene. 2005 Nov 17;24(51):7552-66.

PMID:
16044151
27.

mda-7/IL-24: exploiting cancer's Achilles' heel.

Lebedeva IV, Sauane M, Gopalkrishnan RV, Sarkar D, Su ZZ, Gupta P, Nemunaitis J, Cunningham C, Yacoub A, Dent P, Fisher PB.

Mol Ther. 2005 Jan;11(1):4-18. Review.

28.

Mechanistic aspects of mda-7/IL-24 cancer cell selectivity analysed via a bacterial fusion protein.

Sauane M, Gopalkrishnan RV, Choo HT, Gupta P, Lebedeva IV, Yacoub A, Dent P, Fisher PB.

Oncogene. 2004 Oct 7;23(46):7679-90.

PMID:
15334067
29.

MDA-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells.

Yacoub A, Mitchell C, Hong Y, Gopalkrishnan RV, Su ZZ, Gupta P, Sauane M, Lebedeva IV, Curiel DT, Mahasreshti PJ, Rosenfeld MR, Broaddus WC, James CD, Grant S, Fisher PB, Dent P.

Cancer Biol Ther. 2004 Aug;3(8):739-51. Epub 2004 Aug 10.

PMID:
15197348
30.

Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways.

Sauane M, Lebedeva IV, Su ZZ, Choo HT, Randolph A, Valerie K, Dent P, Gopalkrishnan RV, Fisher PB.

Cancer Res. 2004 May 1;64(9):2988-93.

31.

Cytokine and tumor cell apoptosis inducing activity of mda-7/IL-24.

Gopalkrishnan RV, Sauane M, Fisher PB.

Int Immunopharmacol. 2004 May;4(5):635-47. Review.

PMID:
15120649
32.

Leukaemia inhibitory factor or oncostatin M induction of Swiss 3T3 cells does not require mevalonic acid synthesis nor protein isoprenylation to initiate DNA replication.

Sauane M, Coso OA, Giulianelli S, Giráldez AN, Rudland PS, Jimenez de Asua L.

Biochem Biophys Res Commun. 2004 Jan 23;313(4):926-30.

PMID:
14706631
33.

Mda-7/IL-24 induces apoptosis of diverse cancer cell lines through JAK/STAT-independent pathways.

Sauane M, Gopalkrishnan RV, Lebedeva I, Mei MX, Sarkar D, Su ZZ, Kang DC, Dent P, Pestka S, Fisher PB.

J Cell Physiol. 2003 Aug;196(2):334-45.

PMID:
12811827
34.

Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.

Su ZZ, Lebedeva IV, Sarkar D, Gopalkrishnan RV, Sauane M, Sigmon C, Yacoub A, Valerie K, Dent P, Fisher PB.

Oncogene. 2003 Feb 27;22(8):1164-80.

PMID:
12606943
35.

MDA-7/IL-24: novel cancer growth suppressing and apoptosis inducing cytokine.

Sauane M, Gopalkrishnan RV, Sarkar D, Su ZZ, Lebedeva IV, Dent P, Pestka S, Fisher PB.

Cytokine Growth Factor Rev. 2003 Feb;14(1):35-51. Review.

PMID:
12485618
36.

mda-7 (IL-24): signaling and functional roles.

Sarkar D, Su ZZ, Lebedeva IV, Sauane M, Gopalkrishnan RV, Dent P, Fisher PB.

Biotechniques. 2002 Oct;Suppl:30-9.

PMID:
12395925
37.

mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.

Sarkar D, Su ZZ, Lebedeva IV, Sauane M, Gopalkrishnan RV, Valerie K, Dent P, Fisher PB.

Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):10054-9. Epub 2002 Jul 11.

38.

Prostaglandin F(2alpha) (PGF(2alpha)) induces cyclin D1 expression and DNA synthesis via early signaling mechanisms in Swiss mouse 3T3 cells.

Sauane M, Correa L, Rogers F, Krasnapolski M, Barraclough R, Rudland PS, de Asúa LJ.

Biochem Biophys Res Commun. 2000 Apr 2;270(1):11-6.

PMID:
10733897
39.

Leukaemia inhibitory factor induces mitogenesis in Swiss 3T3 cells and selective enhancement via a variety of signalling events.

Levy CS, Sauane M, Rudland PS, Jimenez de Asua L.

Biochem Biophys Res Commun. 1997 Jul 30;236(3):814-8.

PMID:
9245739
40.

Inhibition of nucleoside diphosphate kinase activity by in vitro phosphorylation by protein kinase CK2. Differential phosphorylation of NDP kinases in HeLa cells in culture.

Biondi RM, Engel M, Sauane M, Welter C, Issinger OG, Jiménez de Asúa L, Passeron S.

FEBS Lett. 1996 Dec 9;399(1-2):183-7.

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