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Items: 1 to 50 of 163

1.

Nanoparticles for Immune Cell Reprogramming and Reengineering of Tumor Microenvironment.

Bhise K, Sau S, Alzhrani R, Iyer AK.

Methods Mol Biol. 2020;2097:211-221. doi: 10.1007/978-1-0716-0203-4_13.

PMID:
31776928
2.

Discovering pH triggered charge rebound surface modulated topical nanotherapy against aggressive skin papilloma.

Sahu P, Kashaw SK, Sau S, Kushwah V, Jain S, Iyer AK.

Mater Sci Eng C Mater Biol Appl. 2020 Feb;107:110263. doi: 10.1016/j.msec.2019.110263. Epub 2019 Oct 12.

PMID:
31761163
3.

Improving the therapeutic efficiency of noncoding RNAs in cancers using targeted drug delivery systems.

Alzhrani R, Alsaab HO, Petrovici A, Bhise K, Vanamala K, Sau S, Krinock MJ, Iyer AK.

Drug Discov Today. 2019 Nov 20. pii: S1359-6446(19)30427-1. doi: 10.1016/j.drudis.2019.11.006. [Epub ahead of print] Review.

PMID:
31758914
4.

Removal of an atypical region from a staphylococcal cyclophilin affects its structure, function, stability, and shape.

Seal S, Chowdhury N, Biswas R, Chakraborty T, Sinha D, Bagchi A, Sau S.

Int J Biol Macromol. 2019 Nov 18. pii: S0141-8130(19)34319-3. doi: 10.1016/j.ijbiomac.2019.10.175. [Epub ahead of print]

PMID:
31751734
5.

N-end rule pathway inhibitor sensitizes cancer cells to antineoplastic agents by regulating XIAP and RAD21 protein expression.

Pore SK, Ganguly A, Sau S, Godeshala S, Kanugula AK, Ummanni R, Kotamraju S, Banerjee R.

J Cell Biochem. 2020 Jan;121(1):804-815. doi: 10.1002/jcb.29326. Epub 2019 Aug 12.

PMID:
31407360
6.

A role for the yeast PCNA unloader Elg1 in eliciting the DNA damage checkpoint.

Sau S, Kupiec M.

Curr Genet. 2019 Jul 22. doi: 10.1007/s00294-019-01020-7. [Epub ahead of print] Review.

PMID:
31332476
7.

Nanomaterials for tumor immunomodulation and overcoming current clinical challenges.

Sau S, Alzhrani R, Bhise K, Alsaab HO, Kashaw SK, Iyer AK.

Nanomedicine (Lond). 2019 Jun;14(12):1515-1519. doi: 10.2217/nnm-2019-0109. Epub 2019 Jun 24. No abstract available.

8.

The Yeast PCNA Unloader Elg1 RFC-Like Complex Plays a Role in Eliciting the DNA Damage Checkpoint.

Sau S, Liefshitz B, Kupiec M.

mBio. 2019 Jun 11;10(3). pii: e01159-19. doi: 10.1128/mBio.01159-19.

9.

Total Synthesis of (+)-Strongylophorines 2 and 9.

Dethe DH, Sau SK.

Org Lett. 2019 May 17;21(10):3799-3803. doi: 10.1021/acs.orglett.9b01254. Epub 2019 May 7.

PMID:
31063387
10.

A staphylococcal cyclophilin carries a single domain and unfolds via the formation of an intermediate that preserves cyclosporin A binding activity.

Seal S, Polley S, Sau S.

PLoS One. 2019 Mar 29;14(3):e0210771. doi: 10.1371/journal.pone.0210771. eCollection 2019.

11.

Cobaltaelectro-Catalyzed C-H Activation with Carbon Monoxide or Isocyanides.

Sau SC, Mei R, Struwe J, Ackermann L.

ChemSusChem. 2019 Jul 5;12(13):3023-3027. doi: 10.1002/cssc.201900378. Epub 2019 Apr 24.

PMID:
30897295
12.

PDL-1 Antibody Drug Conjugate for Selective Chemo-Guided Immune Modulation of Cancer.

Sau S, Petrovici A, Alsaab HO, Bhise K, Iyer AK.

Cancers (Basel). 2019 Feb 16;11(2). pii: E232. doi: 10.3390/cancers11020232.

13.

Hitchhiking on chromosomes: A persistence strategy shared by diverse selfish DNA elements.

Sau S, Ghosh SK, Liu YT, Ma CH, Jayaram M.

Plasmid. 2019 Mar;102:19-28. doi: 10.1016/j.plasmid.2019.01.004. Epub 2019 Feb 3. Review.

PMID:
30726706
14.

pH triggered and charge attracted nanogel for simultaneous evaluation of penetration and toxicity against skin cancer: In-vitro and ex-vivo study.

Sahu P, Kashaw SK, Sau S, Kushwah V, Jain S, Agrawal RK, Iyer AK.

Int J Biol Macromol. 2019 May 1;128:740-751. doi: 10.1016/j.ijbiomac.2019.01.147. Epub 2019 Jan 27.

PMID:
30699336
15.

An intramolecular C(sp3)-H imination using PhI-mCPBA.

Bose A, Maiti S, Sau S, Mal P.

Chem Commun (Camb). 2019 Feb 12;55(14):2066-2069. doi: 10.1039/c8cc09100e.

PMID:
30688962
16.

Development of asialoglycoprotein receptor directed nanoparticles for selective delivery of curcumin derivative to hepatocellular carcinoma.

Yousef S, Alsaab HO, Sau S, Iyer AK.

Heliyon. 2018 Dec 22;4(12):e01071. doi: 10.1016/j.heliyon.2018.e01071. eCollection 2018 Dec.

17.

Dimerization ability, denaturation mechanism, and the stability of a staphylococcal phage repressor and its two domains.

Biswas A, Ghosh S, Sinha D, Dutta A, Seal S, Bagchi A, Sau S.

Int J Biol Macromol. 2019 Mar 1;124:903-914. doi: 10.1016/j.ijbiomac.2018.11.263. Epub 2018 Dec 2.

PMID:
30517842
18.

pH Responsive 5-Fluorouracil Loaded Biocompatible Nanogels For Topical Chemotherapy of Aggressive Melanoma.

Sahu P, Kashaw SK, Sau S, Kushwah V, Jain S, Agrawal RK, Iyer AK.

Colloids Surf B Biointerfaces. 2019 Feb 1;174:232-245. doi: 10.1016/j.colsurfb.2018.11.018. Epub 2018 Nov 10.

PMID:
30465998
19.

Exploring the Role of Water Molecules in the Ligand Binding Domain of PDE4B and PDE4D: Virtual Screening Based Molecular Docking of Some Active Scaffolds.

Singh P, Mishra M, Agarwal S, Sau S, Iyer AK, Kashaw SK.

Curr Comput Aided Drug Des. 2019;15(4):334-366. doi: 10.2174/1573409914666181105153543.

PMID:
30394213
20.

Molecular Docking Analysis of Caspase-3 Activators as Potential Anticancer Agents.

Kashaw SK, Agarwal S, Mishra M, Sau S, Iyer AK.

Curr Comput Aided Drug Des. 2019;15(1):55-66. doi: 10.2174/1573409914666181015150731.

PMID:
30324892
21.

NRF2 transcriptionally activates the heat shock factor 1 promoter under oxidative stress and affects survival and migration potential of MCF7 cells.

Paul S, Ghosh S, Mandal S, Sau S, Pal M.

J Biol Chem. 2018 Dec 14;293(50):19303-19316. doi: 10.1074/jbc.RA118.003376. Epub 2018 Oct 11.

22.

Immunotherapy and molecular role of T-cell in PD-1 antibody treated resectable lung cancer patients.

Sau S, Iyer AK.

J Thorac Dis. 2018 Aug;10(8):4682-4685. doi: 10.21037/jtd.2018.07.66. No abstract available.

23.

Tumor hypoxia directed multimodal nanotherapy for overcoming drug resistance in renal cell carcinoma and reprogramming macrophages.

Alsaab HO, Sau S, Alzhrani RM, Cheriyan VT, Polin LA, Vaishampayan U, Rishi AK, Iyer AK.

Biomaterials. 2018 Nov;183:280-294. doi: 10.1016/j.biomaterials.2018.08.053. Epub 2018 Aug 30.

24.

Nano-engineered delivery systems for cancer imaging and therapy: Recent advances, future direction and patent evaluation.

Nabil G, Bhise K, Sau S, Atef M, El-Banna HA, Iyer AK.

Drug Discov Today. 2019 Feb;24(2):462-491. doi: 10.1016/j.drudis.2018.08.009. Epub 2018 Aug 16. Review.

PMID:
30121330
25.

A CARP-1 functional mimetic compound is synergistic with BRAF-targeting in non-small cell lung cancers.

Cheriyan VT, Alsaab H, Sekhar S, Venkatesh J, Mondal A, Vhora I, Sau S, Muthu M, Polin LA, Levi E, Bepler G, Iyer AK, Singh M, Rishi AK.

Oncotarget. 2018 Jul 3;9(51):29680-29697. doi: 10.18632/oncotarget.25671. eCollection 2018 Jul 3.

26.

Combination of Vancomycin and Cefazolin Lipid Nanoparticles for Overcoming Antibiotic Resistance of MRSA.

Bhise K, Sau S, Kebriaei R, Rice SA, Stamper KC, Alsaab HO, Rybak MJ, Iyer AK.

Materials (Basel). 2018 Jul 20;11(7). pii: E1245. doi: 10.3390/ma11071245.

27.

Halo-Bridged Abnormal NHC Palladium(II) Dimer for Catalytic Dehydrogenative Cross-Coupling Reactions of Heteroarenes.

P S, Sau SC, Vardhanapu PK, Mandal SK.

J Org Chem. 2018 Aug 17;83(16):9403-9411. doi: 10.1021/acs.joc.8b01053. Epub 2018 Jul 31.

PMID:
30015486
28.

An integrated computational approach of molecular dynamics simulations, receptor binding studies and pharmacophore mapping analysis in search of potent inhibitors against tuberculosis.

Agarwal S, Verma E, Kumar V, Lall N, Sau S, Iyer AK, Kashaw SK.

J Mol Graph Model. 2018 Aug;83:17-32. doi: 10.1016/j.jmgm.2018.04.019. Epub 2018 May 3.

PMID:
29753941
29.

CD44 directed nanomicellar payload delivery platform for selective anticancer effect and tumor specific imaging of triple negative breast cancer.

Wang Z, Sau S, Alsaab HO, Iyer AK.

Nanomedicine. 2018 Jun;14(4):1441-1454. doi: 10.1016/j.nano.2018.04.004. Epub 2018 Apr 17.

30.

Enantioselective Total Synthesis and Assignment of the Absolute Configuration of the Meroterpenoid (+)-Taondiol.

Dethe DH, Mahapatra S, Sau SK.

Org Lett. 2018 May 4;20(9):2766-2769. doi: 10.1021/acs.orglett.8b00997. Epub 2018 Apr 19.

PMID:
29672071
31.

Paclitaxel and di-fluorinated curcumin loaded in albumin nanoparticles for targeted synergistic combination therapy of ovarian and cervical cancers.

Gawde KA, Sau S, Tatiparti K, Kashaw SK, Mehrmohammadi M, Azmi AS, Iyer AK.

Colloids Surf B Biointerfaces. 2018 Jul 1;167:8-19. doi: 10.1016/j.colsurfb.2018.03.046. Epub 2018 Mar 28.

PMID:
29625422
32.

A staphylococcal anti-sigma factor possesses a single-domain, carries different denaturant-sensitive regions and unfolds via two intermediates.

Sinha D, Mondal R, Mahapa A, Sau K, Chattopadhyaya R, Sau S.

PLoS One. 2018 Apr 5;13(4):e0195416. doi: 10.1371/journal.pone.0195416. eCollection 2018.

33.

Robust Mesoporous CoMo/γ-Al2O3 Catalysts from Cyclodextrin-Based Supramolecular Assemblies for Hydrothermal Processing of Microalgae: Effect of the Preparation Method.

Bleta R, Schiavo B, Corsaro N, Costa P, Giaconia A, Interrante L, Monflier E, Pipitone G, Ponchel A, Sau S, Scialdone O, Tilloy S, Galia A.

ACS Appl Mater Interfaces. 2018 Apr 18;10(15):12562-12579. doi: 10.1021/acsami.7b16185. Epub 2018 Apr 4.

PMID:
29578684
34.

A tumor multicomponent targeting chemoimmune drug delivery system for reprograming the tumor microenvironment and personalized cancer therapy.

Sau S, Tatiparti K, Alsaab HO, Kashaw SK, Iyer AK.

Drug Discov Today. 2018 Jul;23(7):1344-1356. doi: 10.1016/j.drudis.2018.03.003. Epub 2018 Mar 15. Review.

35.

Alanine substitution mutations in the DNA binding region of a global staphylococcal virulence regulator affect its structure, function, and stability.

Mandal S, Ghosh S, Sinha D, Seal S, Mahapa A, Polley S, Saha D, Sau K, Bagchi A, Sau S.

Int J Biol Macromol. 2018 Jul 1;113:1221-1232. doi: 10.1016/j.ijbiomac.2018.03.045. Epub 2018 Mar 12.

PMID:
29545063
36.
37.

Determining the Roles of a Conserved α-Helix in a Global Virulence Regulator from Staphylococcus aureus.

Mahapa A, Mandal S, Sinha D, Sau S, Sau K.

Protein J. 2018 Apr;37(2):103-112. doi: 10.1007/s10930-018-9762-1.

PMID:
29464485
38.

Multifunctional nanoparticles for cancer immunotherapy: A groundbreaking approach for reprogramming malfunctioned tumor environment.

Sau S, Alsaab HO, Bhise K, Alzhrani R, Nabil G, Iyer AK.

J Control Release. 2018 Mar 28;274:24-34. doi: 10.1016/j.jconrel.2018.01.028. Epub 2018 Jan 31. Review.

39.

Biomimetic Enantioselective Total Synthesis of (-)-Petromindole.

Dethe DH, Sau SK.

Org Lett. 2018 Feb 2;20(3):632-635. doi: 10.1021/acs.orglett.7b03768. Epub 2018 Jan 16.

PMID:
29336573
40.

A CARP-1 functional mimetic loaded vitamin E-TPGS micellar nano-formulation for inhibition of renal cell carcinoma.

Cheriyan VT, Alsaab HO, Sekhar S, Stieber C, Kesharwani P, Sau S, Muthu M, Polin LA, Levi E, Iyer AK, Rishi AK.

Oncotarget. 2017 Sep 5;8(62):104928-104945. doi: 10.18632/oncotarget.20650. eCollection 2017 Dec 1.

41.

Structural basis for TNA synthesis by an engineered TNA polymerase.

Chim N, Shi C, Sau SP, Nikoomanzar A, Chaput JC.

Nat Commun. 2017 Nov 27;8(1):1810. doi: 10.1038/s41467-017-02014-0.

42.

Nanomedicine for cancer diagnosis and therapy: advancement, success and structure-activity relationship.

Bhise K, Sau S, Alsaab H, Kashaw SK, Tekade RK, Iyer AK.

Ther Deliv. 2017 Nov;8(11):1003-1018. doi: 10.4155/tde-2017-0062. Review.

PMID:
29061101
43.

Free-ranging dogs prefer petting over food in repeated interactions with unfamiliar humans.

Bhattacharjee D, Sau S, Das J, Bhadra A.

J Exp Biol. 2017 Dec 15;220(Pt 24):4654-4660. doi: 10.1242/jeb.166371. Epub 2017 Oct 16.

44.

Identification and characterization of a CI binding operator at a distant location in the temperate staphylococcal phage ф11.

Biswas A, Mandal S, Sau S.

FEMS Microbiol Lett. 2017 Nov 1;364(20). doi: 10.1093/femsle/fnx201.

PMID:
28961814
45.

PD-1 and PD-L1 Checkpoint Signaling Inhibition for Cancer Immunotherapy: Mechanism, Combinations, and Clinical Outcome.

Alsaab HO, Sau S, Alzhrani R, Tatiparti K, Bhise K, Kashaw SK, Iyer AK.

Front Pharmacol. 2017 Aug 23;8:561. doi: 10.3389/fphar.2017.00561. eCollection 2017. Review.

46.

A Gram-Scale HPLC-Free Synthesis of TNA Triphosphates Using an Iterative Phosphorylation Strategy.

Sau SP, Chaput JC.

Org Lett. 2017 Aug 18;19(16):4379-4382. doi: 10.1021/acs.orglett.7b02099. Epub 2017 Aug 2.

PMID:
28766949
47.

Design, synthesis and antiproliferative activity of decarbonyl luotonin analogues.

Almansour AI, Arumugam N, Suresh Kumar R, Mahalingam SM, Sau S, Bianchini G, Menéndez JC, Altaf M, Ghabbour HA.

Eur J Med Chem. 2017 Sep 29;138:932-941. doi: 10.1016/j.ejmech.2017.07.027. Epub 2017 Jul 18.

PMID:
28753517
48.

pH responsive biodegradable nanogels for sustained release of bleomycin.

Sahu P, Kashaw SK, Kushwah V, Sau S, Jain S, Iyer AK.

Bioorg Med Chem. 2017 Sep 1;25(17):4595-4613. doi: 10.1016/j.bmc.2017.06.038. Epub 2017 Jun 27.

PMID:
28734664
49.

Transition into adult care: factors associated with level of preparedness among adolescents living with HIV in Cambodia.

Yi S, Ngin C, Pal K, Khol V, Tuot S, Sau S, Chhoun P, Mburu G, Choub SC, Chhim K, Ly P.

AIDS Res Ther. 2017 Jul 17;14(1):33. doi: 10.1186/s12981-017-0159-6.

50.

Free-ranging dogs show age related plasticity in their ability to follow human pointing.

Bhattacharjee D, N ND, Gupta S, Sau S, Sarkar R, Biswas A, Banerjee A, Babu D, Mehta D, Bhadra A.

PLoS One. 2017 Jul 17;12(7):e0180643. doi: 10.1371/journal.pone.0180643. eCollection 2017.

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