Sort by
Items per page

Send to

Choose Destination

Search results

Items: 46


Foxo3 Promotes Apoptosis of B Cell Receptor-Stimulated Immature B Cells, Thus Limiting the Window for Receptor Editing.

Ottens K, Hinman RM, Barrios E, Skaug B, Davis LS, Li QZ, Castrillon DH, Satterthwaite AB.

J Immunol. 2018 Aug 1;201(3):940-949. doi: 10.4049/jimmunol.1701070. Epub 2018 Jun 27.


Bruton's Tyrosine Kinase, a Component of B Cell Signaling Pathways, Has Multiple Roles in the Pathogenesis of Lupus.

Satterthwaite AB.

Front Immunol. 2018 Jan 22;8:1986. doi: 10.3389/fimmu.2017.01986. eCollection 2017. Review.


Pathways leading to an immunological disease: systemic lupus erythematosus.

Zharkova O, Celhar T, Cravens PD, Satterthwaite AB, Fairhurst AM, Davis LS.

Rheumatology (Oxford). 2017 Apr 1;56(suppl_1):i55-i66. doi: 10.1093/rheumatology/kew427. Review.


Leukocyte Beta-Catenin Expression Is Disturbed in Systemic Lupus Erythematosus.

Orme JJ, Du Y, Vanarsa K, Wu T, Satterthwaite AB, Mohan C.

PLoS One. 2016 Aug 22;11(8):e0161682. doi: 10.1371/journal.pone.0161682. eCollection 2016.


Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE.

Orme JJ, Du Y, Vanarsa K, Mayeux J, Li L, Mutwally A, Arriens C, Min S, Hutcheson J, Davis LS, Chong BF, Satterthwaite AB, Wu T, Mohan C.

Clin Immunol. 2016 Aug;169:58-68. doi: 10.1016/j.clim.2016.05.011. Epub 2016 May 27.


The Role of the Transcription Factor Ets1 in Lupus and Other Autoimmune Diseases.

Garrett-Sinha LA, Kearly A, Satterthwaite AB.

Crit Rev Immunol. 2016;36(6):485-510. doi: 10.1615/CritRevImmunol.2017020284.


Genetic Interaction between Lyn, Ets1, and Btk in the Control of Antibody Levels.

Mayeux J, Skaug B, Luo W, Russell LM, John S, Saelee P, Abbasi H, Li QZ, Garrett-Sinha LA, Satterthwaite AB.

J Immunol. 2015 Sep 1;195(5):1955-63. doi: 10.4049/jimmunol.1500165. Epub 2015 Jul 24.


A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels.

Luo W, Mayeux J, Gutierrez T, Russell L, Getahun A, Müller J, Tedder T, Parnes J, Rickert R, Nitschke L, Cambier J, Satterthwaite AB, Garrett-Sinha LA.

J Immunol. 2014 Jul 15;193(2):909-920. doi: 10.4049/jimmunol.1400666. Epub 2014 Jun 13.


SLE peripheral blood B cell, T cell and myeloid cell transcriptomes display unique profiles and each subset contributes to the interferon signature.

Becker AM, Dao KH, Han BK, Kornu R, Lakhanpal S, Mobley AB, Li QZ, Lian Y, Wu T, Reimold AM, Olsen NJ, Karp DR, Chowdhury FZ, Farrar JD, Satterthwaite AB, Mohan C, Lipsky PE, Wakeland EK, Davis LS.

PLoS One. 2013 Jun 24;8(6):e67003. doi: 10.1371/journal.pone.0067003. Print 2013.


IL-21 promotes the production of anti-DNA IgG but is dispensable for kidney damage in lyn-/- mice.

Gutierrez T, Mayeux JM, Ortega SB, Karandikar NJ, Li QZ, Rakheja D, Zhou XJ, Satterthwaite AB.

Eur J Immunol. 2013 Feb;43(2):382-93. doi: 10.1002/eji.201142095. Epub 2012 Dec 18.


Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus.

Hutcheson J, Vanarsa K, Bashmakov A, Grewal S, Sajitharan D, Chang BY, Buggy JJ, Zhou XJ, Du Y, Satterthwaite AB, Mohan C.

Arthritis Res Ther. 2012 Nov 8;14(6):R243. doi: 10.1186/ar4086.


Genetics: Rare genes for autoimmunity-the new kids on the block.

Satterthwaite AB, Mohan C.

Nat Rev Rheumatol. 2010 Dec;6(12):678-9. doi: 10.1038/nrrheum.2010.177. No abstract available.


Separate checkpoints regulate splenic plasma cell accumulation and IgG autoantibody production in Lyn-deficient mice.

Gutierrez T, Halcomb KE, Coughran AJ, Li QZ, Satterthwaite AB.

Eur J Immunol. 2010 Jul;40(7):1897-905. doi: 10.1002/eji.200940043.


Foxo3-/- mice demonstrate reduced numbers of pre-B and recirculating B cells but normal splenic B cell sub-population distribution.

Hinman RM, Nichols WA, Diaz TM, Gallardo TD, Castrillon DH, Satterthwaite AB.

Int Immunol. 2009 Jul;21(7):831-42. doi: 10.1093/intimm/dxp049. Epub 2009 Jun 5.


Btk regulates localization, in vivo activation, and class switching of anti-DNA B cells.

Halcomb KE, Musuka S, Gutierrez T, Wright HL, Satterthwaite AB.

Mol Immunol. 2008 Dec;46(2):233-41. doi: 10.1016/j.molimm.2008.08.278. Epub 2008 Oct 11.


Shared signaling networks active in B cells isolated from genetically distinct mouse models of lupus.

Wu T, Qin X, Kurepa Z, Kumar KR, Liu K, Kanta H, Zhou XJ, Satterthwaite AB, Davis LS, Mohan C.

J Clin Invest. 2007 Aug;117(8):2186-96.


Btk and phospholipase C gamma 2 can function independently during B cell development.

Halcomb KE, Contreras CM, Hinman RM, Coursey TG, Wright HL, Satterthwaite AB.

Eur J Immunol. 2007 Apr;37(4):1033-42.


Btk regulates multiple stages in the development and survival of B-1 cells.

Contreras CM, Halcomb KE, Randle L, Hinman RM, Gutierrez T, Clarke SH, Satterthwaite AB.

Mol Immunol. 2007 Apr;44(10):2719-28. Epub 2007 Jan 4.


Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication.

Pisitkun P, Deane JA, Difilippantonio MJ, Tarasenko T, Satterthwaite AB, Bolland S.

Science. 2006 Jun 16;312(5780):1669-72. Epub 2006 May 18.


Btk plays a crucial role in the amplification of Fc epsilonRI-mediated mast cell activation by kit.

Iwaki S, Tkaczyk C, Satterthwaite AB, Halcomb K, Beaven MA, Metcalfe DD, Gilfillan AM.

J Biol Chem. 2005 Dec 2;280(48):40261-70. Epub 2005 Sep 21.


NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and Fc epsilon RI aggregation.

Tkaczyk C, Horejsi V, Iwaki S, Draber P, Samelson LE, Satterthwaite AB, Nahm DH, Metcalfe DD, Gilfillan AM.

Blood. 2004 Jul 1;104(1):207-14. Epub 2004 Mar 9.


Reduced dosage of Bruton's tyrosine kinase uncouples B cell hyperresponsiveness from autoimmunity in lyn-/- mice.

Whyburn LR, Halcomb KE, Contreras CM, Lowell CA, Witte ON, Satterthwaite AB.

J Immunol. 2003 Aug 15;171(4):1850-8.


Haploinsufficiency of B cell linker protein enhances B cell signaling defects in mice expressing a limiting dosage of Bruton's tyrosine kinase.

Whyburn LR, Halcomb KE, Contreras CM, Pappu R, Witte ON, Chan AC, Satterthwaite AB.

Int Immunol. 2003 Mar;15(3):383-92.


Complementary roles for CD19 and Bruton's tyrosine kinase in B lymphocyte signal transduction.

Fujimoto M, Poe JC, Satterthwaite AB, Wahl MI, Witte ON, Tedder TF.

J Immunol. 2002 Jun 1;168(11):5465-76.


Phosphoinositide 3-kinase and Bruton's tyrosine kinase regulate overlapping sets of genes in B lymphocytes.

Fruman DA, Ferl GZ, An SS, Donahue AC, Satterthwaite AB, Witte ON.

Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):359-64. Epub 2001 Dec 26.


Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome.

Le LQ, Kabarowski JH, Weng Z, Satterthwaite AB, Harvill ET, Jensen ER, Miller JF, Witte ON.

Immunity. 2001 May;14(5):561-71.


The role of Bruton's tyrosine kinase in B-cell development and function: a genetic perspective.

Satterthwaite AB, Witte ON.

Immunol Rev. 2000 Jun;175:120-7. Review.


Xid-like phenotypes: a B cell signalosome takes shape.

Fruman DA, Satterthwaite AB, Witte ON.

Immunity. 2000 Jul;13(1):1-3. Review. No abstract available.


Redundant and opposing functions of two tyrosine kinases, Btk and Lyn, in mast cell activation.

Kawakami Y, Kitaura J, Satterthwaite AB, Kato RM, Asai K, Hartman SE, Maeda-Yamamoto M, Lowell CA, Rawlings DJ, Witte ON, Kawakami T.

J Immunol. 2000 Aug 1;165(3):1210-9.


A sensitized genetic system for the analysis of murine B lymphocyte signal transduction pathways dependent on Bruton's tyrosine kinase.

Satterthwaite AB, Willis F, Kanchanastit P, Fruman D, Cantley LC, Helgason CD, Humphries RK, Lowell CA, Simon M, Leitges M, Tarakhovsky A, Tedder TF, Lesche R, Wu H, Witte ON.

Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6687-92.


Posttranscriptional regulation of Bruton's tyrosine kinase expression in antigen receptor-stimulated splenic B cells.

Nisitani S, Satterthwaite AB, Akashi K, Weissman IL, Witte ON, Wahl MI.

Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2737-42. Erratum in: Proc Natl Acad Sci U S A 2000 May 9;97(10):5679.


A nuclear factor Y (NFY) site positively regulates the human CD34 stem cell gene.

Radomska HS, Satterthwaite AB, Taranenko N, Narravula S, Krause DS, Tenen DG.

Blood. 1999 Dec 1;94(11):3772-80.


A Btk transgene restores the antiviral TI-2 antibody responses of xid mice in a dose-dependent fashion.

Pinschewer DD, Ochsenbein AF, Satterthwaite AB, Witte ON, Hengartner H, Zinkernagel RM.

Eur J Immunol. 1999 Sep;29(9):2981-7.


Multiple control elements are required for expression of the human CD34 gene.

Radomska HS, Satterthwaite AB, Burn TC, Oliff IA, Huettner CS, Tenen DG.

Gene. 1998 Nov 19;222(2):305-18. Erratum in: Gene 1999 Oct 18;239(1):203.


DSHP: a "power bar" for sustained immune responses?

Satterthwaite AB, Rawlings DJ, Witte ON.

Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13355-7. No abstract available.


Independent and opposing roles for Btk and lyn in B and myeloid signaling pathways.

Satterthwaite AB, Lowell CA, Khan WN, Sideras P, Alt FW, Witte ON.

J Exp Med. 1998 Sep 7;188(5):833-44.


Btk function in B cell development and response.

Satterthwaite AB, Li Z, Witte ON.

Semin Immunol. 1998 Aug;10(4):309-16. Review.


Btk dosage determines sensitivity to B cell antigen receptor cross-linking.

Satterthwaite AB, Cheroutre H, Khan WN, Sideras P, Witte ON.

Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):13152-7.


Constitutive membrane association potentiates activation of Bruton tyrosine kinase.

Li T, Rawlings DJ, Park H, Kato RM, Witte ON, Satterthwaite AB.

Oncogene. 1997 Sep 18;15(12):1375-83.


Lessons from human genetic variants in the study of B-cell differentiation.

Satterthwaite AB, Witte ON.

Curr Opin Immunol. 1996 Aug;8(4):454-8. Review.


Structure of the gene encoding CD34, a human hematopoietic stem cell antigen.

Satterthwaite AB, Burn TC, Le Beau MM, Tenen DG.

Genomics. 1992 Apr;12(4):788-94.


Molecular cloning of a cDNA encoding CD34, a sialomucin of human hematopoietic stem cells.

Simmons DL, Satterthwaite AB, Tenen DG, Seed B.

J Immunol. 1992 Jan 1;148(1):267-71.


Regulation of the gene for CD34, a human hematopoietic stem cell antigen, in KG-1 cells.

Satterthwaite AB, Borson R, Tenen DG.

Blood. 1990 Jun 15;75(12):2299-304.


Chromosome 1 localization of the gene for CD34, a surface antigen of human stem cells.

Tenen DG, Satterthwaite AB, Borson R, Simmons D, Eddy RL, Shows TB.

Cytogenet Cell Genet. 1990;53(1):55-7.


Supplemental Content

Loading ...
Support Center