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Items: 18

1.

Characterization of CYP2C Induction in Cryopreserved Human Hepatocytes and Its Application in the Prediction of the Clinical Consequences of the Induction.

Nagai M, Hosaka T, Satsukawa M, Yoshinari K.

J Pharm Sci. 2018 Sep;107(9):2479-2488. doi: 10.1016/j.xphs.2018.05.008. Epub 2018 May 23.

PMID:
29802934
2.

Prediction of human percutaneous absorption from in vitro and in vivo animal experiments.

Yoshimatsu H, Ishii K, Konno Y, Satsukawa M, Yamashita S.

Int J Pharm. 2017 Dec 20;534(1-2):348-355. doi: 10.1016/j.ijpharm.2017.10.048. Epub 2017 Oct 28.

PMID:
29111099
3.

Establishment of In Silico Prediction Models for CYP3A4 and CYP2B6 Induction in Human Hepatocytes by Multiple Regression Analysis Using Azole Compounds.

Nagai M, Konno Y, Satsukawa M, Yamashita S, Yoshinari K.

Drug Metab Dispos. 2016 Aug;44(8):1390-8. doi: 10.1124/dmd.115.068619. Epub 2016 May 20.

PMID:
27208383
4.

Usefulness of minipigs for predicting human pharmacokinetics: Prediction of distribution volume and plasma clearance.

Yoshimatsu H, Konno Y, Ishii K, Satsukawa M, Yamashita S.

Drug Metab Pharmacokinet. 2016 Feb;31(1):73-81. doi: 10.1016/j.dmpk.2015.11.001. Epub 2015 Nov 18.

PMID:
26776246
5.

Survey on the tiered approach for Japanese bioanalysts operated by Japan bioanalysis forum DG2014-09.

Niwa M, Koseki N, Hashimoto Y, Mayumi T, Nishimura N, Satsukawa M, Uchimura T, Yasuda Y, Yokoi H.

Bioanalysis. 2016;8(2):93-8. doi: 10.4155/bio.15.236. Epub 2015 Dec 10. No abstract available.

PMID:
26653036
6.

Identification of putative substrates for cynomolgus monkey cytochrome P450 2C8 by substrate depletion assays with 22 human P450 substrates and inhibitors.

Hosaka S, Murayama N, Satsukawa M, Uehara S, Shimizu M, Iwasaki K, Iwano S, Uno Y, Yamazaki H.

Biopharm Drug Dispos. 2016 Jul;37(5):310-3. doi: 10.1002/bdd.1998.

PMID:
26581561
7.

Similar substrate specificity of cynomolgus monkey cytochrome P450 2C19 to reported human P450 2C counterpart enzymes by evaluation of 89 drug clearances.

Hosaka S, Murayama N, Satsukawa M, Uehara S, Shimizu M, Iwasaki K, Iwano S, Uno Y, Yamazaki H.

Biopharm Drug Dispos. 2015 Dec;36(9):636-43. doi: 10.1002/bdd.1991.

PMID:
26348733
8.

Tiered approach to metabolite quantification: regional practices reviewed by Japan Bioanalysis Forum discussion group.

Niwa M, Uchimura T, Koseki N, Satsukawa M, Hashimoto Y, Mayumi T, Yasuda Y, Yokoi H.

Bioanalysis. 2015;7(8):935-8. doi: 10.4155/bio.15.34. No abstract available.

PMID:
25966006
9.

Comprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz Oxidase.

Hosaka S, Murayama N, Satsukawa M, Uehara S, Shimizu M, Iwasaki K, Iwano S, Uno Y, Yamazaki H.

Drug Metab Dispos. 2015 Jul;43(7):1119-22. doi: 10.1124/dmd.115.063925. Epub 2015 May 6.

PMID:
25948712
10.

Multiparametric assay using HepaRG cells for predicting drug-induced liver injury.

Tomida T, Okamura H, Satsukawa M, Yokoi T, Konno Y.

Toxicol Lett. 2015 Jul 2;236(1):16-24. doi: 10.1016/j.toxlet.2015.04.014. Epub 2015 Apr 28.

PMID:
25934330
11.

Evaluation of 89 compounds for identification of substrates for cynomolgus monkey CYP2C76, a new bupropion/nifedipine oxidase.

Hosaka S, Murayama N, Satsukawa M, Shimizu M, Uehara S, Fujino H, Iwasaki K, Iwano S, Uno Y, Yamazaki H.

Drug Metab Dispos. 2015 Jan;43(1):27-33. doi: 10.1124/dmd.114.061275. Epub 2014 Oct 15.

PMID:
25318994
12.

Quantitative assessment of intestinal first-pass metabolism of oral drugs using portal-vein cannulated rats.

Matsuda Y, Konno Y, Hashimoto T, Nagai M, Taguchi T, Satsukawa M, Yamashita S.

Pharm Res. 2015 Feb;32(2):604-16. doi: 10.1007/s11095-014-1489-x. Epub 2014 Aug 28.

PMID:
25163980
13.

Lead evaluation of tetrahydroquinolines as nonsteroidal selective androgen receptor modulators for the treatment of osteoporosis.

Nagata N, Furuya K, Oguro N, Nishiyama D, Kawai K, Yamamoto N, Ohyabu Y, Satsukawa M, Miyakawa M.

ChemMedChem. 2014 Jan;9(1):197-206. doi: 10.1002/cmdc.201300348. Epub 2013 Nov 22.

PMID:
24273094
14.

In vivo assessment of the impact of efflux transporter on oral drug absorption using portal vein-cannulated rats.

Matsuda Y, Konno Y, Hashimoto T, Nagai M, Taguchi T, Satsukawa M, Yamashita S.

Drug Metab Dispos. 2013 Aug;41(8):1514-21. doi: 10.1124/dmd.113.051680. Epub 2013 May 16.

PMID:
23686319
15.

Assessment of intestinal availability of various drugs in the oral absorption process using portal vein-cannulated rats.

Matsuda Y, Konno Y, Satsukawa M, Kobayashi T, Takimoto Y, Morisaki K, Yamashita S.

Drug Metab Dispos. 2012 Dec;40(12):2231-8. doi: 10.1124/dmd.112.048223. Epub 2012 Aug 28.

PMID:
22930277
16.

Soluble fiber viscosity affects both goblet cell number and small intestine mucin secretion in rats.

Ito H, Satsukawa M, Arai E, Sugiyama K, Sonoyama K, Kiriyama S, Morita T.

J Nutr. 2009 Sep;139(9):1640-7. doi: 10.3945/jn.109.110171. Epub 2009 Jul 15.

PMID:
19605529
17.

Molecular cloning and functions of rat liver hydroxysteroid sulfotransferases catalysing covalent binding of carcinogenic polycyclic arylmethanols to DNA.

Watabe T, Ogura K, Satsukawa M, Okuda H, Hiratsuka A.

Chem Biol Interact. 1994 Jun;92(1-3):87-105. Review.

PMID:
8033273
18.

Major hydroxysteroid sulfotransferase STa in rat liver cytosol may consist of two microheterogeneous subunits.

Ogura K, Satsukawa M, Okuda H, Hiratsuka A, Watabe T.

Chem Biol Interact. 1994 Jun;92(1-3):129-44.

PMID:
8033248

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