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Items: 1 to 50 of 297

1.

Nano-elastic liposomes as multidrug carrier of sodium stibogluconate and ketoconazole: A potential new approach for the topical treatment of cutaneous Leishmaniasis.

Dar MJ, Khalid S, Varikuti S, Satoskar AR, Khan GM.

Eur J Pharm Sci. 2020 Feb 4;145:105256. doi: 10.1016/j.ejps.2020.105256. [Epub ahead of print]

PMID:
32032778
2.

Ibrutinib treatment inhibits breast cancer progression and metastasis by inducing conversion of myeloid-derived suppressor cells to dendritic cells.

Varikuti S, Singh B, Volpedo G, Ahirwar DK, Jha BK, Saljoughian N, Viana AG, Verma C, Hamza O, Halsey G, Holcomb EA, Maryala RJ, Oghumu S, Ganju RK, Satoskar AR.

Br J Cancer. 2020 Feb 6. doi: 10.1038/s41416-020-0743-8. [Epub ahead of print]

PMID:
32025027
3.

Immune Suppression Mediated by STAT4 Deficiency Promotes Lymphatic Metastasis in HNSCC.

Anderson K, Ryan N, Volpedo G, Varikuti S, Satoskar AR, Oghumu S.

Front Immunol. 2020 Jan 15;10:3095. doi: 10.3389/fimmu.2019.03095. eCollection 2019.

4.

Development and evaluation of novel miltefosine-polyphenol co-loaded second generation nano-transfersomes for the topical treatment of cutaneous leishmaniasis.

Dar MJ, McElroy CA, Khan MI, Satoskar AR, Khan GM.

Expert Opin Drug Deliv. 2020 Jan;17(1):97-110. doi: 10.1080/17425247.2020.1700227. Epub 2019 Dec 6.

PMID:
31786952
5.

Topical treatment of cutaneous leishmaniasis with novel amphotericin B-miltefosine co-incorporated second generation ultra-deformable liposomes.

Dar MJ, Khalid S, McElroy CA, Satoskar AR, Khan GM.

Int J Pharm. 2020 Jan 5;573:118900. doi: 10.1016/j.ijpharm.2019.118900. Epub 2019 Nov 22.

PMID:
31765786
6.

Lymphocytes influence Leishmania major pathogenesis in a strain-dependent manner.

Musa MA, Nakamura R, Hena A, Varikuti S, Nakhasi HL, Goto Y, Satoskar AR, Hamano S.

PLoS Negl Trop Dis. 2019 Nov 18;13(11):e0007865. doi: 10.1371/journal.pntd.0007865. eCollection 2019 Nov.

7.

STAT1 inhibits T-cell exhaustion and myeloid derived suppressor cell accumulation to promote antitumor immune responses in head and neck squamous cell carcinoma.

Ryan N, Anderson K, Volpedo G, Hamza O, Varikuti S, Satoskar AR, Oghumu S.

Int J Cancer. 2020 Mar 15;146(6):1717-1729. doi: 10.1002/ijc.32781. Epub 2019 Nov 29.

PMID:
31709529
8.

MiR-16 regulates crosstalk in NF-κB tolerogenic inflammatory signaling between myeloma cells and bone marrow macrophages.

Khalife J, Ghose J, Martella M, Viola D, Rocci A, Troadec E, Terrazas C, Satoskar AR, Gunes EG, Dona A, Sanchez JF, Bergsagel PL, Chesi M, Pozhitkov A, Rosen S, Marcucci G, Keats JJ, Hofmeister CC, Krishnan A, Caserta E, Pichiorri F.

JCI Insight. 2019 Nov 1;4(21). pii: 129348. doi: 10.1172/jci.insight.129348.

9.

Evaluation of synergy between host and pathogen-directed therapies against intracellular Leishmania donovani.

Zahid MSH, Johnson MM, Tokarski RJ 2nd, Satoskar AR, Fuchs JR, Bachelder EM, Ainslie KM.

Int J Parasitol Drugs Drug Resist. 2019 Aug;10:125-132. doi: 10.1016/j.ijpddr.2019.08.004. Epub 2019 Aug 21.

10.

Anti-PD-1 Immunotherapy May Induce Interstitial Nephritis With Increased Tubular Epithelial Expression of PD-L1.

Cassol C, Satoskar A, Lozanski G, Rovin B, Hebert L, Nadasdy T, Brodsky SV.

Kidney Int Rep. 2019 Jun 20;4(8):1152-1160. doi: 10.1016/j.ekir.2019.06.001. eCollection 2019 Aug.

11.

Lost in Transportation: Calcium Oxalate Crystals in Kidney Biopsy Specimens Fixed in Michel Medium May Disappear.

Cassol CA, Braga JR, Hartage R, Satoskar AA, Nadasdy T, Brodsky SV.

Arch Pathol Lab Med. 2019 Aug 12. doi: 10.5858/arpa.2019-0088-OA. [Epub ahead of print]

PMID:
31403332
12.

Epidemiology, pathogenesis, treatment and outcomes of infection-associated glomerulonephritis.

Satoskar AA, Parikh SV, Nadasdy T.

Nat Rev Nephrol. 2020 Jan;16(1):32-50. doi: 10.1038/s41581-019-0178-8. Epub 2019 Aug 9. Review.

PMID:
31399725
13.

Host-directed therapies for parasitic diseases.

Singh B, Varikuti S, Halsey G, Volpedo G, Hamza OM, Satoskar AR.

Future Med Chem. 2019 Aug;11(15):1999-2018. doi: 10.4155/fmc-2018-0439. Epub 2019 Aug 8.

PMID:
31390889
14.

Immunostaining for galactose-deficient immunoglobulin A is not specific for primary immunoglobulin A nephropathy.

Cassol CA, Bott C, Nadasdy GM, Alberton V, Malvar A, Nagaraja HN, Nadasdy T, Rovin BH, Satoskar AA.

Nephrol Dial Transplant. 2019 Aug 1. pii: gfz152. doi: 10.1093/ndt/gfz152. [Epub ahead of print]

PMID:
31369128
15.

Eculizumab deposits in vessel walls in thrombotic microangiopathy.

Cassol CA, Brodsky SV, Satoskar AA, Blissett AR, Cataland S, Nadasdy T.

Kidney Int. 2019 Sep;96(3):761-768. doi: 10.1016/j.kint.2019.05.008. Epub 2019 May 24.

PMID:
31345584
16.

Cutting Edge: CXCR3 Escapes X Chromosome Inactivation in T Cells during Infection: Potential Implications for Sex Differences in Immune Responses.

Oghumu S, Varikuti S, Stock JC, Volpedo G, Saljoughian N, Terrazas CA, Satoskar AR.

J Immunol. 2019 Aug 15;203(4):789-794. doi: 10.4049/jimmunol.1800931. Epub 2019 Jun 28.

PMID:
31253729
17.

Taenia crassiceps-Excreted/Secreted Products Induce a Defined MicroRNA Profile that Modulates Inflammatory Properties of Macrophages.

Martínez-Saucedo D, Ruíz-Rosado JD, Terrazas C, Callejas BE, Satoskar AR, Partida-Sánchez S, Terrazas LI.

J Immunol Res. 2019 May 14;2019:2946713. doi: 10.1155/2019/2946713. eCollection 2019.

18.

MicroRNA 155 Contributes to Host Immunity against Leishmania donovani but Is Not Essential for Resolution of Infection.

Varikuti S, Natarajan G, Volpedo G, Singh B, Hamza O, Messick GV, Guerau-de-Arellano M, Papenfuss TL, Oghumu S, Satoskar AR.

Infect Immun. 2019 Jul 23;87(8). pii: e00307-19. doi: 10.1128/IAI.00307-19. Print 2019 Aug.

19.

Nanoparticulate drug delivery systems for the treatment of neglected tropical protozoan diseases.

Volpedo G, Costa L, Ryan N, Halsey G, Satoskar A, Oghumu S.

J Venom Anim Toxins Incl Trop Dis. 2019 Feb 11;25:e144118. doi: 10.1590/1678-9199-JVATITD-1441-18. eCollection 2019.

20.

Complete biopsy-proven resolution of deposits in recurrent proliferative glomerulonephritis with monoclonal IgG deposits (PGNMIGD) following rituximab treatment in renal allograft.

Von Visger J, Cassol C, Nori U, Franco-Ahumada G, Nadasdy T, Satoskar AA.

BMC Nephrol. 2019 Feb 14;20(1):53. doi: 10.1186/s12882-019-1239-8.

21.

Elevated Expression of Macrophage Migration Inhibitory Factor Promotes Inflammatory Bone Resorption Induced in a Mouse Model of Periradicular Periodontitis.

Howait M, Albassam A, Yamada C, Sasaki H, Bahammam L, Azuma MM, Cintra LTA, Satoskar AR, Yamada S, White R, Kawai T, Movila A.

J Immunol. 2019 Apr 1;202(7):2035-2043. doi: 10.4049/jimmunol.1801161. Epub 2019 Feb 8.

PMID:
30737274
22.

Mannosylated thiolated paromomycin-loaded PLGA nanoparticles for the oral therapy of visceral leishmaniasis.

Afzal I, Sarwar HS, Sohail MF, Varikuti S, Jahan S, Akhtar S, Yasinzai M, Satoskar AR, Shahnaz G.

Nanomedicine (Lond). 2019 Feb;14(4):387-406. doi: 10.2217/nnm-2018-0038. Epub 2019 Jan 28.

PMID:
30688557
23.

Host-Directed Drug Therapies for Neglected Tropical Diseases Caused by Protozoan Parasites.

Varikuti S, Jha BK, Volpedo G, Ryan NM, Halsey G, Hamza OM, McGwire BS, Satoskar AR.

Front Microbiol. 2018 Nov 30;9:2655. doi: 10.3389/fmicb.2018.02655. eCollection 2018. Review.

24.

Zonal cortical scarring and tubular thyroidization in kidney biopsies of patients with SLE-histologic indicator for antiphospholipid antibodies.

Shah R, Brodsky SV, Hebert L, Rovin BH, Nadasdy T, Satoskar AA.

Lupus. 2018 Dec;27(14):2236-2244. doi: 10.1177/0961203318809177. Epub 2018 Nov 7.

PMID:
30403144
25.

Bacterial endocarditis manifesting as autoimmune pulmonary renal syndrome: ANCA-associated lung hemorrhage and pauci-immune crescentic glomerulonephritis
.

Mohandes S, Satoskar A, Hebert L, Ayoub I.

Clin Nephrol. 2018 Dec;90(6):431-433. doi: 10.5414/CN109495.

PMID:
30369400
26.

Daratumumab induces CD38 internalization and impairs myeloma cell adhesion.

Ghose J, Viola D, Terrazas C, Caserta E, Troadec E, Khalife J, Gunes EG, Sanchez J, McDonald T, Marcucci G, Kaur B, Rosenzweig M, Keats J, Rosen S, Krishnan A, Satoskar AR, Hofmeister CC, Pichiorri F.

Oncoimmunology. 2018 Jul 23;7(10):e1486948. doi: 10.1080/2162402X.2018.1486948. eCollection 2018.

27.

The Potent ITK/BTK Inhibitor Ibrutinib Is Effective for the Treatment of Experimental Visceral Leishmaniasis Caused by Leishmania donovani.

Varikuti S, Volpedo G, Saljoughian N, Hamza OM, Halsey G, Ryan NM, Sedmak BE, Seidler GR, Papenfuss TL, Oghumu S, Satoskar AR.

J Infect Dis. 2019 Jan 29;219(4):599-608. doi: 10.1093/infdis/jiy552.

28.

Deficiency in STAT1 Signaling Predisposes Gut Inflammation and Prompts Colorectal Cancer Development.

Leon-Cabrera S, Vázquez-Sandoval A, Molina-Guzman E, Delgado-Ramirez Y, Delgado-Buenrostro NL, Callejas BE, Chirino YI, Pérez-Plasencia C, Rodríguez-Sosa M, Olguín JE, Salinas C, Satoskar AR, Terrazas LI.

Cancers (Basel). 2018 Sep 19;10(9). pii: E341. doi: 10.3390/cancers10090341.

29.

Intestinal Epithelial Cells Regulate Gut Eotaxin Responses and Severity of Allergy.

Kim E, Lembert M, Fallata GM, Rowe JC, Martin TL, Satoskar AR, Reo NV, Paliy O, Cormet-Boyaka E, Boyaka PN.

Front Immunol. 2018 Aug 3;9:1692. doi: 10.3389/fimmu.2018.01692. eCollection 2018.

30.

STAT4 is required for the generation of Th1 and Th2, but not Th17 immune responses during monophosphoryl lipid A adjuvant activity.

Varikuti S, Oghumu S, Natarajan G, Kimble J, Sperling RH, Moretti E, Kaplan MH, Satoskar AR.

Int Immunol. 2018 Jul 24;30(8):385. doi: 10.1093/intimm/dxy037. No abstract available.

31.

Rifampicin in Nontuberculous Mycobacterial Infections: Acute Kidney Injury with Hemoglobin Casts.

Kora R, Brodsky SV, Nadasdy T, Agra D, Satoskar AA.

Case Rep Nephrol. 2018 Apr 5;2018:9321621. doi: 10.1155/2018/9321621. eCollection 2018.

32.

Fibroblast-derived CXCL12 promotes breast cancer metastasis by facilitating tumor cell intravasation.

Ahirwar DK, Nasser MW, Ouseph MM, Elbaz M, Cuitiño MC, Kladney RD, Varikuti S, Kaul K, Satoskar AR, Ramaswamy B, Zhang X, Ostrowski MC, Leone G, Ganju RK.

Oncogene. 2018 Aug;37(32):4428-4442. doi: 10.1038/s41388-018-0263-7. Epub 2018 May 3.

PMID:
29720724
33.

Inhibitors of elastase stimulate murine B lymphocyte differentiation into IgG- and IgA-producing cells.

Attia Z, Rowe JC, Kim E, Varikuti S, Steiner HE, Zaghawa A, Hassan H, Cormet-Boyaka E, Satoskar AR, Boyaka PN.

Eur J Immunol. 2018 Aug;48(8):1295-1301. doi: 10.1002/eji.201747264. Epub 2018 Jul 5.

34.

Acute glomerulonephritis with large confluent IgA-dominant deposits associated with liver cirrhosis.

Hemminger J, Arole V, Ayoub I, Brodsky SV, Nadasdy T, Satoskar AA.

PLoS One. 2018 Apr 10;13(4):e0193274. doi: 10.1371/journal.pone.0193274. eCollection 2018.

35.

IL-27 gene therapy induces depletion of Tregs and enhances the efficacy of cancer immunotherapy.

Zhu J, Liu JQ, Shi M, Cheng X, Ding M, Zhang JC, Davis JP, Varikuti S, Satoskar AR, Lu L, Pan X, Zheng P, Liu Y, Bai XF.

JCI Insight. 2018 Apr 5;3(7). pii: 98745. doi: 10.1172/jci.insight.98745. eCollection 2018 Apr 5.

36.

Editorial: Cell Signaling in Host-Pathogen Interactions: The Host Point of View.

Bahia D, Satoskar AR, Dussurget O.

Front Immunol. 2018 Feb 19;9:221. doi: 10.3389/fimmu.2018.00221. eCollection 2018. No abstract available.

37.

Design of mannosylated oral amphotericin B nanoformulation: efficacy and safety in visceral leishmaniasis.

Sarwar HS, Sohail MF, Saljoughian N, Rehman AU, Akhtar S, Nadhman A, Yasinzai M, Gendelman HE, Satoskar AR, Shahnaz G.

Artif Cells Nanomed Biotechnol. 2018;46(sup1):521-531. doi: 10.1080/21691401.2018.1430699. Epub 2018 Jan 31.

PMID:
29385910
38.

Acute kidney injury aggravated by treatment initiation with apixaban: Another twist of anticoagulant-related nephropathy.

Brodsky SV, Mhaskar NS, Thiruveedi S, Dhingra R, Reuben SC, Calomeni E, Ivanov I, Satoskar A, Hemminger J, Nadasdy G, Hebert L, Rovin B, Nadasdy T.

Kidney Res Clin Pract. 2017 Dec;36(4):387-392. doi: 10.23876/j.krcp.2017.36.4.387. Epub 2017 Dec 31.

39.

Inhibition of Macrophage Complement Receptor CRIg by TRIM72 Polarizes Innate Immunity of the Lung.

Nagre N, Cong X, Terrazas C, Pepper I, Schreiber JM, Fu H, Sill JM, Christman JW, Satoskar AR, Zhao X.

Am J Respir Cell Mol Biol. 2018 Jun;58(6):756-766. doi: 10.1165/rcmb.2017-0236OC.

40.

STAT1 gene deficient mice develop accelerated breast cancer growth and metastasis which is reduced by IL-17 blockade.

Varikuti S, Oghumu S, Elbaz M, Volpedo G, Ahirwar DK, Alarcon PC, Sperling RH, Moretti E, Pioso MS, Kimble J, Nasser MW, Ganju RK, Terrazas C, Satoskar AR.

Oncoimmunology. 2017 Aug 14;6(11):e1361088. doi: 10.1080/2162402X.2017.1361088. eCollection 2017.

41.

Ly6Chi inflammatory monocytes promote susceptibility to Leishmania donovani infection.

Terrazas C, Varikuti S, Oghumu S, Steinkamp HM, Ardic N, Kimble J, Nakhasi H, Satoskar AR.

Sci Rep. 2017 Oct 31;7(1):14693. doi: 10.1038/s41598-017-14935-3.

42.

MIF Inhibitor ISO-1 Protects Photoreceptors and Reduces Gliosis in Experimental Retinal Detachment.

Kim B, Kusibati R, Heisler-Taylor T, Mantopoulos D, Ding J, Abdel-Rahman MH, Satoskar AR, Godbout JP, Bhattacharya SK, Cebulla CM.

Sci Rep. 2017 Oct 30;7(1):14336. doi: 10.1038/s41598-017-14298-9.

43.

Pentalinonsterol, a Constituent of Pentalinon andrieuxii, Possesses Potent Immunomodulatory Activity and Primes T Cell Immune Responses.

Oghumu S, Varikuti S, Saljoughian N, Terrazas C, Huntsman AC, Parinandi NL, Fuchs JR, Kinghorn AD, Satoskar AR.

J Nat Prod. 2017 Sep 22;80(9):2515-2523. doi: 10.1021/acs.jnatprod.7b00445. Epub 2017 Sep 6.

44.

Efficacy, Safety and Cost-Effectiveness of Thermotherapy in the Treatment of Leishmania donovani-Induced Cutaneous Leishmaniasis: A Randomized Controlled Clinical Trial.

Refai WF, Madarasingha NP, Sumanasena B, Weerasingha S, De Silva A, Fernandopulle R, Satoskar AR, Karunaweera ND.

Am J Trop Med Hyg. 2017 Oct;97(4):1120-1126. doi: 10.4269/ajtmh.16-0879. Epub 2017 Aug 18.

45.

Interleukin-27 signalling induces stem cell antigen-1 expression in T lymphocytes in vivo.

Liu Z, Wu L, Zhu J, Zhu X, Zhu J, Liu JQ, Zhang J, Davis JP, Varikuti S, Satoskar AR, Zhou J, Li MS, Bai XF.

Immunology. 2017 Dec;152(4):638-647. doi: 10.1111/imm.12805. Epub 2017 Aug 23.

46.

Topical treatment with nanoliposomal Amphotericin B reduces early lesion growth but fails to induce cure in an experimental model of cutaneous leishmaniasis caused by Leishmania mexicana.

Varikuti S, Oghumu S, Saljoughian N, Pioso MS, Sedmak BE, Khamesipour A, Satoskar AR.

Acta Trop. 2017 Sep;173:102-108. doi: 10.1016/j.actatropica.2017.06.004. Epub 2017 Jun 9.

47.

In situ immunopathological changes in cutaneous leishmaniasis due to Leishmania donovani.

Manamperi NH, Oghumu S, Pathirana N, de Silva MV, Abeyewickreme W, Satoskar AR, Karunaweera ND.

Parasite Immunol. 2017 Mar;39(3). doi: 10.1111/pim.12413.

48.

Helminth-induced Ly6Chi monocyte-derived alternatively activated macrophages suppress experimental autoimmune encephalomyelitis.

Terrazas C, de Dios Ruiz-Rosado J, Amici SA, Jablonski KA, Martinez-Saucedo D, Webb LM, Cortado H, Robledo-Avila F, Oghumu S, Satoskar AR, Rodriguez-Sosa M, Terrazas LI, Guerau-de-Arellano M, Partida-Sánchez S.

Sci Rep. 2017 Jan 17;7:40814. doi: 10.1038/srep40814.

49.

Staphylococcus Infection-Associated GN - Spectrum of IgA Staining and Prevalence of ANCA in a Single-Center Cohort.

Satoskar AA, Suleiman S, Ayoub I, Hemminger J, Parikh S, Brodsky SV, Bott C, Calomeni E, Nadasdy GM, Rovin B, Hebert L, Nadasdy T.

Clin J Am Soc Nephrol. 2017 Jan 6;12(1):39-49. doi: 10.2215/CJN.05070516. Epub 2016 Nov 7.

50.

Granuloma formation in leishmaniasis: A mathematical model.

Siewe N, Yakubu AA, Satoskar AR, Friedman A.

J Theor Biol. 2017 Jan 7;412:48-60. doi: 10.1016/j.jtbi.2016.10.004. Epub 2016 Oct 18.

PMID:
27769685

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