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Items: 13

1.

Efficient Modification of the CCR5 Locus in Primary Human T Cells With megaTAL Nuclease Establishes HIV-1 Resistance.

Romano Ibarra GS, Paul B, Sather BD, Younan PM, Sommer K, Kowalski JP, Hale M, Stoddard B, Jarjour J, Astrakhan A, Kiem HP, Rawlings DJ.

Mol Ther Nucleic Acids. 2016 Aug 23;5(8):e352. doi: 10.1038/mtna.2016.56.

2.

Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template.

Sather BD, Romano Ibarra GS, Sommer K, Curinga G, Hale M, Khan IF, Singh S, Song Y, Gwiazda K, Sahni J, Jarjour J, Astrakhan A, Wagner TA, Scharenberg AM, Rawlings DJ.

Sci Transl Med. 2015 Sep 30;7(307):307ra156. doi: 10.1126/scitranslmed.aac5530.

3.

Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells.

Wang CX, Sather BD, Wang X, Adair J, Khan I, Singh S, Lang S, Adams A, Curinga G, Kiem HP, Miao CH, Rawlings DJ, Torbett BE.

Blood. 2014 Aug 7;124(6):913-23. doi: 10.1182/blood-2013-12-546218. Epub 2014 Jun 9.

4.

Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors RORγt and Ahr that leads to IL-17 production by activated B cells.

Bermejo DA, Jackson SW, Gorosito-Serran M, Acosta-Rodriguez EV, Amezcua-Vesely MC, Sather BD, Singh AK, Khim S, Mucci J, Liggitt D, Campetella O, Oukka M, Gruppi A, Rawlings DJ.

Nat Immunol. 2013 May;14(5):514-22. doi: 10.1038/ni.2569. Epub 2013 Apr 7.

5.

Ubiquitous high-level gene expression in hematopoietic lineages provides effective lentiviral gene therapy of murine Wiskott-Aldrich syndrome.

Astrakhan A, Sather BD, Ryu BY, Khim S, Singh S, Humblet-Baron S, Ochs HD, Miao CH, Rawlings DJ.

Blood. 2012 May 10;119(19):4395-407. doi: 10.1182/blood-2011-03-340711. Epub 2012 Mar 19.

6.

WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity.

Becker-Herman S, Meyer-Bahlburg A, Schwartz MA, Jackson SW, Hudkins KL, Liu C, Sather BD, Khim S, Liggitt D, Song W, Silverman GJ, Alpers CE, Rawlings DJ.

J Exp Med. 2011 Sep 26;208(10):2033-42. doi: 10.1084/jem.20110200. Epub 2011 Aug 29.

7.

Development of B-lineage predominant lentiviral vectors for use in genetic therapies for B cell disorders.

Sather BD, Ryu BY, Stirling BV, Garibov M, Kerns HM, Humblet-Baron S, Astrakhan A, Rawlings DJ.

Mol Ther. 2011 Mar;19(3):515-25. doi: 10.1038/mt.2010.259. Epub 2010 Dec 7.

8.

Cellular requirements for diabetes induction in DO11.10xRIPmOVA mice.

Wesley JD, Sather BD, Perdue NR, Ziegler SF, Campbell DJ.

J Immunol. 2010 Oct 15;185(8):4760-8. doi: 10.4049/jimmunol.1000820. Epub 2010 Sep 20.

9.

B cell-specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia.

Kerns HM, Ryu BY, Stirling BV, Sather BD, Astrakhan A, Humblet-Baron S, Liggitt D, Rawlings DJ.

Blood. 2010 Mar 18;115(11):2146-55. doi: 10.1182/blood-2009-09-241869. Epub 2010 Jan 21.

10.

Altering the distribution of Foxp3(+) regulatory T cells results in tissue-specific inflammatory disease.

Sather BD, Treuting P, Perdue N, Miazgowicz M, Fontenot JD, Rudensky AY, Campbell DJ.

J Exp Med. 2007 Jun 11;204(6):1335-47. Epub 2007 Jun 4.

11.

Regulatory T cells maintain long-term tolerance to myelin basic protein by inducing a novel, dynamic state of T cell tolerance.

Cabbage SE, Huseby ES, Sather BD, Brabb T, Liggitt D, Goverman J.

J Immunol. 2007 Jan 15;178(2):887-96.

12.

Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors.

Teague RM, Sather BD, Sacks JA, Huang MZ, Dossett ML, Morimoto J, Tan X, Sutton SE, Cooke MP, Ohlén C, Greenberg PD.

Nat Med. 2006 Mar;12(3):335-41. Epub 2006 Feb 12.

PMID:
16474399
13.

CD8(+) T cell tolerance to a tumor-associated antigen is maintained at the level of expansion rather than effector function.

Ohlén C, Kalos M, Cheng LE, Shur AC, Hong DJ, Carson BD, Kokot NC, Lerner CG, Sather BD, Huseby ES, Greenberg PD.

J Exp Med. 2002 Jun 3;195(11):1407-18.

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