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Items: 24


Non-muscle Myosin II drives vesicle loss during human reticulocyte maturation.

Moura PL, Hawley BR, Mankelow TJ, Griffiths RE, Dobbe JGG, Streekstra GJ, Anstee DJ, Satchwell TJ, Toye AM.

Haematologica. 2018 Aug 3. pii: haematol.2018.199083. doi: 10.3324/haematol.2018.199083. [Epub ahead of print]


Quantitative measurement of red cell surface protein expression reveals new biomarkers for hereditary spherocytosis.

Huisjes R, Satchwell TJ, Verhagen LP, Schiffelers RM, van Solinge WW, Toye AM, van Wijk R.

Int J Lab Hematol. 2018 Aug;40(4):e74-e77. doi: 10.1111/ijlh.12841. Epub 2018 May 10. No abstract available.


Enhancement of red blood cell transfusion compatibility using CRISPR-mediated erythroblast gene editing.

Hawksworth J, Satchwell TJ, Meinders M, Daniels DE, Regan F, Thornton NM, Wilson MC, Dobbe JG, Streekstra GJ, Trakarnsanga K, Heesom KJ, Anstee DJ, Frayne J, Toye AM.

EMBO Mol Med. 2018 Jun;10(6). pii: e8454. doi: 10.15252/emmm.201708454.


CD47 surface stability is sensitive to actin disruption prior to inclusion within the band 3 macrocomplex.

Mordue KE, Hawley BR, Satchwell TJ, Toye AM.

Sci Rep. 2017 May 22;7(1):2246. doi: 10.1038/s41598-017-02356-1.


Plasmodium falciparum erythrocyte-binding antigen 175 triggers a biophysical change in the red blood cell that facilitates invasion.

Koch M, Wright KE, Otto O, Herbig M, Salinas ND, Tolia NH, Satchwell TJ, Guck J, Brooks NJ, Baum J.

Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4225-4230. doi: 10.1073/pnas.1620843114. Epub 2017 Apr 3.


An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells.

Trakarnsanga K, Griffiths RE, Wilson MC, Blair A, Satchwell TJ, Meinders M, Cogan N, Kupzig S, Kurita R, Nakamura Y, Toye AM, Anstee DJ, Frayne J.

Nat Commun. 2017 Mar 14;8:14750. doi: 10.1038/ncomms14750.


A new junctional hierarchy.

Satchwell TJ, Toye AM.

Blood. 2016 Jul 7;128(1):11-2. doi: 10.1182/blood-2016-05-711788. No abstract available.


Severe Ankyrin-R deficiency results in impaired surface retention and lysosomal degradation of RhAG in human erythroblasts.

Satchwell TJ, Bell AJ, Hawley BR, Pellegrin S, Mordue KE, van Deursen CT, Braak NH, Huls G, Leers MP, Overwater E, Tamminga RY, van der Zwaag B, Fermo E, Bianchi P, van Wijk R, Toye AM.

Haematologica. 2016 Sep;101(9):1018-27. doi: 10.3324/haematol.2016.146209. Epub 2016 May 31.


Erythrocyte invasion receptors for Plasmodium falciparum: new and old.

Satchwell TJ.

Transfus Med. 2016 Apr;26(2):77-88. doi: 10.1111/tme.12280. Epub 2016 Feb 9. Review.


Quantitative phospho-proteomics reveals the Plasmodium merozoite triggers pre-invasion host kinase modification of the red cell cytoskeleton.

Zuccala ES, Satchwell TJ, Angrisano F, Tan YH, Wilson MC, Heesom KJ, Baum J.

Sci Rep. 2016 Feb 2;6:19766. doi: 10.1038/srep19766.


The sorting of blood group active proteins during enucleation.

Satchwell TJ, Bell AJ, Toye AM.

ISBT Sci Ser. 2015 Apr 1;10(Suppl 1):163-168.


The cytoskeletal binding domain of band 3 is required for multiprotein complex formation and retention during erythropoiesis.

Satchwell TJ, Hawley BR, Bell AJ, Ribeiro ML, Toye AM.

Haematologica. 2015 Jan;100(1):133-42. doi: 10.3324/haematol.2014.114538. Epub 2014 Oct 24.


Membrane-wrapping contributions to malaria parasite invasion of the human erythrocyte.

Dasgupta S, Auth T, Gov NS, Satchwell TJ, Hanssen E, Zuccala ES, Riglar DT, Toye AM, Betz T, Baum J, Gompper G.

Biophys J. 2014 Jul 1;107(1):43-54. doi: 10.1016/j.bpj.2014.05.024.


Characteristic phenotypes associated with congenital dyserythropoietic anemia (type II) manifest at different stages of erythropoiesis.

Satchwell TJ, Pellegrin S, Bianchi P, Hawley BR, Gampel A, Mordue KE, Budnik A, Fermo E, Barcellini W, Stephens DJ, van den Akker E, Toye AM.

Haematologica. 2013 Nov;98(11):1788-96. doi: 10.3324/haematol.2013.085522. Epub 2013 Aug 9.


Protein distribution during human erythroblast enucleation in vitro.

Bell AJ, Satchwell TJ, Heesom KJ, Hawley BR, Kupzig S, Hazell M, Mushens R, Herman A, Toye AM.

PLoS One. 2013;8(4):e60300. doi: 10.1371/journal.pone.0060300. Epub 2013 Apr 2.


Differential proteomic analysis of human erythroblasts undergoing apoptosis induced by epo-withdrawal.

Pellegrin S, Heesom KJ, Satchwell TJ, Hawley BR, Daniels G, van den Akker E, Toye AM.

PLoS One. 2012;7(6):e38356. doi: 10.1371/journal.pone.0038356. Epub 2012 Jun 18.


Refined views of multi-protein complexes in the erythrocyte membrane.

Mankelow TJ, Satchwell TJ, Burton NM.

Blood Cells Mol Dis. 2012 Jun 15;49(1):1-10. doi: 10.1016/j.bcmd.2012.03.001. Epub 2012 Mar 31. Review.


Critical band 3 multiprotein complex interactions establish early during human erythropoiesis.

Satchwell TJ, Bell AJ, Pellegrin S, Kupzig S, Ridgwell K, Daniels G, Anstee DJ, van den Akker E, Toye AM.

Blood. 2011 Jul 7;118(1):182-191. doi: 10.1182/blood-2010-10-314187. Epub 2011 Apr 28.


Anion exchanger 1 in red blood cells and kidney: Band 3's in a pod.

Wu F, Satchwell TJ, Toye AM.

Biochem Cell Biol. 2011 Apr;89(2):106-14. doi: 10.1139/o10-146. Review.


Anion exchanger 1 interacts with nephrin in podocytes.

Wu F, Saleem MA, Kampik NB, Satchwell TJ, Williamson RC, Blattner SM, Ni L, Toth T, White G, Young MT, Parker MD, Alper SL, Wagner CA, Toye AM.

J Am Soc Nephrol. 2010 Sep;21(9):1456-67. doi: 10.1681/ASN.2009090921. Epub 2010 Jun 24.


The majority of the in vitro erythroid expansion potential resides in CD34(-) cells, outweighing the contribution of CD34(+) cells and significantly increasing the erythroblast yield from peripheral blood samples.

van den Akker E, Satchwell TJ, Pellegrin S, Daniels G, Toye AM.

Haematologica. 2010 Sep;95(9):1594-8. doi: 10.3324/haematol.2009.019828. Epub 2010 Apr 7.


Band 3 multiprotein complexes in the red cell membrane; of mice and men.

van den Akker E, Satchwell TJ, Williamson RC, Toye AM.

Blood Cells Mol Dis. 2010 Jun 15;45(1):1-8. doi: 10.1016/j.bcmd.2010.02.019. Epub 2010 Mar 25. Review.


Investigating the key membrane protein changes during in vitro erythropoiesis of protein 4.2 (-) cells (mutations Chartres 1 and 2).

van den Akker E, Satchwell TJ, Pellegrin S, Flatt JF, Maigre M, Daniels G, Delaunay J, Bruce LJ, Toye AM.

Haematologica. 2010 Aug;95(8):1278-86. doi: 10.3324/haematol.2009.021063. Epub 2010 Feb 23.


Protein 4.2: a complex linker.

Satchwell TJ, Shoemark DK, Sessions RB, Toye AM.

Blood Cells Mol Dis. 2009 May-Jun;42(3):201-10. doi: 10.1016/j.bcmd.2009.01.005. Epub 2009 Mar 9. Review.


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