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Items: 1 to 50 of 71

1.

Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis.

Marie KL, Sassano A, Yang HH, Michalowski AM, Michael HT, Guo T, Tsai YC, Weissman AM, Lee MP, Jenkins LM, Zaidi MR, Pérez-Guijarro E, Day CP, Ylaya K, Hewitt SM, Patel NL, Arnheiter H, Davis S, Meltzer PS, Merlino G, Mishra PJ.

Nat Commun. 2020 Jan 16;11(1):333. doi: 10.1038/s41467-019-14085-2.

2.

Slfn2 Regulates Type I Interferon Responses by Modulating the NF-κB Pathway.

Fischietti M, Arslan AD, Sassano A, Saleiro D, Majchrzak-Kita B, Ebine K, Munshi HG, Fish EN, Platanias LC.

Mol Cell Biol. 2018 Jul 30;38(16). pii: e00053-18. doi: 10.1128/MCB.00053-18. Print 2018 Aug 15.

3.

Blocked vs. interleaved presentation and proactive interference in episodic memory.

Del Missier F, Sassano A, Coni V, Salomonsson M, Mäntylä T.

Memory. 2018 May;26(5):697-711. doi: 10.1080/09658211.2017.1402937. Epub 2017 Nov 13.

PMID:
29130368
4.

Human SLFN5 is a transcriptional co-repressor of STAT1-mediated interferon responses and promotes the malignant phenotype in glioblastoma.

Arslan AD, Sassano A, Saleiro D, Lisowski P, Kosciuczuk EM, Fischietti M, Eckerdt F, Fish EN, Platanias LC.

Oncogene. 2017 Oct 26;36(43):6006-6019. doi: 10.1038/onc.2017.205. Epub 2017 Jul 3.

5.

Statins as anti-cancer therapy; Can we translate preclinical and epidemiologic data into clinical benefit?

Chae YK, Yousaf M, Malecek MK, Carneiro B, Chandra S, Kaplan J, Kalyan A, Sassano A, Platanias LC, Giles F.

Discov Med. 2015 Dec;20(112):413-27.

6.

Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells.

Sassano A, Mavrommatis E, Arslan AD, Kroczynska B, Beauchamp EM, Khuon S, Chew TL, Green KJ, Munshi HG, Verma AK, Platanias LC.

Mol Cell Biol. 2015 Aug;35(15):2684-98. doi: 10.1128/MCB.00019-15. Epub 2015 May 26.

7.

The effect of body position on developing ultrasound criteria for the assessment of the internal jugular vein.

Clements E, Bonfield M, Sassano A.

Ultrasound. 2015 May;23(2):85-9. doi: 10.1177/1742271X15576272. Epub 2015 Mar 12.

8.

Autophagy is a survival mechanism of acute myelogenous leukemia precursors during dual mTORC2/mTORC1 targeting.

Altman JK, Szilard A, Goussetis DJ, Sassano A, Colamonici M, Gounaris E, Frankfurt O, Giles FJ, Eklund EA, Beauchamp EM, Platanias LC.

Clin Cancer Res. 2014 May 1;20(9):2400-9. doi: 10.1158/1078-0432.CCR-13-3218. Epub 2014 Mar 7.

9.

Critical roles for Rictor/Sin1 complexes in interferon-dependent gene transcription and generation of antiproliferative responses.

Kaur S, Kroczynska B, Sharma B, Sassano A, Arslan AD, Majchrzak-Kita B, Stein BL, McMahon B, Altman JK, Su B, Calogero RA, Fish EN, Platanias LC.

J Biol Chem. 2014 Mar 7;289(10):6581-91. doi: 10.1074/jbc.M113.537852. Epub 2014 Jan 27.

10.

Expression and regulatory effects of murine Schlafen (Slfn) genes in malignant melanoma and renal cell carcinoma.

Mavrommatis E, Arslan AD, Sassano A, Hua Y, Kroczynska B, Platanias LC.

J Biol Chem. 2013 Nov 15;288(46):33006-15. doi: 10.1074/jbc.M113.460741. Epub 2013 Oct 2.

11.

Antileukemic properties of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors.

van Besien H, Sassano A, Altman JK, Platanias LC.

Leuk Lymphoma. 2013 Dec;54(12):2601-5. doi: 10.3109/10428194.2013.790022. Epub 2013 Jul 29. Review.

PMID:
23540342
12.

Inhibition of Mnk kinase activity by cercosporamide and suppressive effects on acute myeloid leukemia precursors.

Altman JK, Szilard A, Konicek BW, Iversen PW, Kroczynska B, Glaser H, Sassano A, Vakana E, Graff JR, Platanias LC.

Blood. 2013 May 2;121(18):3675-81. doi: 10.1182/blood-2013-01-477216. Epub 2013 Mar 18.

13.

Regulation of the kinase RSK1 by arsenic trioxide and generation of antileukemic responses.

Galvin JP, Altman JK, Szilard A, Goussetis DJ, Vakana E, Sassano A, Platanias LC.

Cancer Biol Ther. 2013 May;14(5):411-6. doi: 10.4161/cbt.23760. Epub 2013 Feb 1.

14.

Sprouty proteins are negative regulators of interferon (IFN) signaling and IFN-inducible biological responses.

Sharma B, Joshi S, Sassano A, Majchrzak B, Kaur S, Aggarwal P, Nabet B, Bulic M, Stein BL, McMahon B, Baker DP, Fukunaga R, Altman JK, Licht JD, Fish EN, Platanias LC.

J Biol Chem. 2012 Dec 7;287(50):42352-60. doi: 10.1074/jbc.M112.400721. Epub 2012 Oct 16.

15.

Regulatory effects of mTORC2 complexes in type I IFN signaling and in the generation of IFN responses.

Kaur S, Sassano A, Majchrzak-Kita B, Baker DP, Su B, Fish EN, Platanias LC.

Proc Natl Acad Sci U S A. 2012 May 15;109(20):7723-8. doi: 10.1073/pnas.1118122109. Epub 2012 May 1.

16.

Statin-dependent activation of protein kinase Cδ in acute promyelocytic leukemia cells and induction of leukemic cell differentiation.

Sassano A, Altman JK, Gordon LI, Platanias LC.

Leuk Lymphoma. 2012 Sep;53(9):1779-84. doi: 10.3109/10428194.2012.668287. Epub 2012 Apr 19.

17.

Targeting mTOR for the treatment of AML. New agents and new directions.

Altman JK, Sassano A, Platanias LC.

Oncotarget. 2011 Jun;2(6):510-7. Review.

18.

Dual mTORC2/mTORC1 targeting results in potent suppressive effects on acute myeloid leukemia (AML) progenitors.

Altman JK, Sassano A, Kaur S, Glaser H, Kroczynska B, Redig AJ, Russo S, Barr S, Platanias LC.

Clin Cancer Res. 2011 Jul 1;17(13):4378-88. doi: 10.1158/1078-0432.CCR-10-2285. Epub 2011 Mar 17.

19.

Role of interferon {alpha} (IFN{alpha})-inducible Schlafen-5 in regulation of anchorage-independent growth and invasion of malignant melanoma cells.

Katsoulidis E, Mavrommatis E, Woodard J, Shields MA, Sassano A, Carayol N, Sawicki KT, Munshi HG, Platanias LC.

J Biol Chem. 2010 Dec 17;285(51):40333-41. doi: 10.1074/jbc.M110.151076. Epub 2010 Oct 18.

20.

Induction of autophagy by dual mTORC1-mTORC2 inhibition in BCR-ABL-expressing leukemic cells.

Vakana E, Sassano A, Platanias LC.

Autophagy. 2010 Oct;6(7):966-7. doi: 10.1073/pnas.1005114107. Epub 2010 Oct 19.

PMID:
20699667
21.

Negative regulatory effects of Mnk kinases in the generation of chemotherapy-induced antileukemic responses.

Altman JK, Glaser H, Sassano A, Joshi S, Ueda T, Watanabe-Fukunaga R, Fukunaga R, Tallman MS, Platanias LC.

Mol Pharmacol. 2010 Oct;78(4):778-84. doi: 10.1124/mol.110.064642. Epub 2010 Jul 27.

22.

Critical roles for mTORC2- and rapamycin-insensitive mTORC1-complexes in growth and survival of BCR-ABL-expressing leukemic cells.

Carayol N, Vakana E, Sassano A, Kaur S, Goussetis DJ, Glaser H, Druker BJ, Donato NJ, Altman JK, Barr S, Platanias LC.

Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12469-74. doi: 10.1073/pnas.1005114107. Epub 2010 Jun 28.

23.

All trans retinoic acid nanodisks enhance retinoic acid receptor mediated apoptosis and cell cycle arrest in mantle cell lymphoma.

Singh AT, Evens AM, Anderson RJ, Beckstead JA, Sankar N, Sassano A, Bhalla S, Yang S, Platanias LC, Forte TM, Ryan RO, Gordon LI.

Br J Haematol. 2010 Jul;150(2):158-69. doi: 10.1111/j.1365-2141.2010.08209.x. Epub 2010 May 9.

24.

Arsenic trioxide-dependent activation of thousand-and-one amino acid kinase 2 and transforming growth factor-beta-activated kinase 1.

McNeer JL, Goussetis DJ, Sassano A, Dolniak B, Kroczynska B, Glaser H, Altman JK, Platanias LC.

Mol Pharmacol. 2010 May;77(5):828-35. doi: 10.1124/mol.109.061507. Epub 2010 Feb 16.

25.

Role of Schlafen 2 (SLFN2) in the generation of interferon alpha-induced growth inhibitory responses.

Katsoulidis E, Carayol N, Woodard J, Konieczna I, Majchrzak-Kita B, Jordan A, Sassano A, Eklund EA, Fish EN, Platanias LC.

J Biol Chem. 2009 Sep 11;284(37):25051-64. doi: 10.1074/jbc.M109.030445. Epub 2009 Jul 10.

26.

Interferon-dependent engagement of eukaryotic initiation factor 4B via S6 kinase (S6K)- and ribosomal protein S6K-mediated signals.

Kroczynska B, Kaur S, Katsoulidis E, Majchrzak-Kita B, Sassano A, Kozma SC, Fish EN, Platanias LC.

Mol Cell Biol. 2009 May;29(10):2865-75. doi: 10.1128/MCB.01537-08. Epub 2009 Mar 16.

27.

Regulation of leukemic cell differentiation and retinoid-induced gene expression by statins.

Sassano A, Lo Iacono M, Antico G, Jordan A, Uddin S, Calogero RA, Platanias LC.

Mol Cancer Ther. 2009 Mar;8(3):615-25. doi: 10.1158/1535-7163.MCT-08-1196. Epub 2009 Feb 24.

28.

Activation of protein kinase C{eta} by type I interferons.

Redig AJ, Sassano A, Majchrzak-Kita B, Katsoulidis E, Liu H, Altman JK, Fish EN, Wickrema A, Platanias LC.

J Biol Chem. 2009 Apr 17;284(16):10301-14. doi: 10.1074/jbc.M807254200. Epub 2009 Feb 11.

29.

Protein kinase C-delta and phosphatidylinositol 3-kinase/Akt activate mammalian target of rapamycin to modulate NF-kappaB activation and intercellular adhesion molecule-1 (ICAM-1) expression in endothelial cells.

Minhajuddin M, Bijli KM, Fazal F, Sassano A, Nakayama KI, Hay N, Platanias LC, Rahman A.

J Biol Chem. 2009 Feb 13;284(7):4052-61. doi: 10.1074/jbc.M805032200. Epub 2008 Dec 13.

30.

Dual regulatory roles of phosphatidylinositol 3-kinase in IFN signaling.

Kaur S, Sassano A, Joseph AM, Majchrzak-Kita B, Eklund EA, Verma A, Brachmann SM, Fish EN, Platanias LC.

J Immunol. 2008 Nov 15;181(10):7316-23.

31.

Statin-dependent suppression of the Akt/mammalian target of rapamycin signaling cascade and programmed cell death 4 up-regulation in renal cell carcinoma.

Woodard J, Sassano A, Hay N, Platanias LC.

Clin Cancer Res. 2008 Jul 15;14(14):4640-9. doi: 10.1158/1078-0432.CCR-07-5232.

32.

Role of the Akt pathway in mRNA translation of interferon-stimulated genes.

Kaur S, Sassano A, Dolniak B, Joshi S, Majchrzak-Kita B, Baker DP, Hay N, Fish EN, Platanias LC.

Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4808-13. doi: 10.1073/pnas.0710907105. Epub 2008 Mar 13.

33.

Suppression of interferon (IFN)-inducible genes and IFN-mediated functional responses in BCR-ABL-expressing cells.

Katsoulidis E, Sassano A, Majchrzak-Kita B, Carayol N, Yoon P, Jordan A, Druker BJ, Fish EN, Platanias LC.

J Biol Chem. 2008 Apr 18;283(16):10793-803. doi: 10.1074/jbc.M706816200. Epub 2008 Feb 20.

34.

Role of the translational repressor 4E-BP1 in the regulation of p21(Waf1/Cip1) expression by retinoids.

Kannan-Thulasiraman P, Dolniak B, Kaur S, Sassano A, Kalvakolanu DV, Hay N, Platanias LC.

Biochem Biophys Res Commun. 2008 Apr 18;368(4):983-9. doi: 10.1016/j.bbrc.2008.02.028. Epub 2008 Feb 15.

35.

Suppression of programmed cell death 4 (PDCD4) protein expression by BCR-ABL-regulated engagement of the mTOR/p70 S6 kinase pathway.

Carayol N, Katsoulidis E, Sassano A, Altman JK, Druker BJ, Platanias LC.

J Biol Chem. 2008 Mar 28;283(13):8601-10. doi: 10.1074/jbc.M707934200. Epub 2008 Jan 26.

36.

Statins in tumor suppression.

Sassano A, Platanias LC.

Cancer Lett. 2008 Feb 18;260(1-2):11-9. doi: 10.1016/j.canlet.2007.11.036. Epub 2008 Jan 3. Review.

PMID:
18180097
37.

Regulatory effects of mammalian target of rapamycin-mediated signals in the generation of arsenic trioxide responses.

Altman JK, Yoon P, Katsoulidis E, Kroczynska B, Sassano A, Redig AJ, Glaser H, Jordan A, Tallman MS, Hay N, Platanias LC.

J Biol Chem. 2008 Jan 25;283(4):1992-2001. Epub 2007 Nov 29.

38.

Suppressive effects of statins on acute promyelocytic leukemia cells.

Sassano A, Katsoulidis E, Antico G, Altman JK, Redig AJ, Minucci S, Tallman MS, Platanias LC.

Cancer Res. 2007 May 1;67(9):4524-32.

39.

Activation of mammalian target of rapamycin and the p70 S6 kinase by arsenic trioxide in BCR-ABL-expressing cells.

Yoon P, Giafis N, Smith J, Mears H, Katsoulidis E, Sassano A, Altman J, Redig AJ, Tallman MS, Platanias LC.

Mol Cancer Ther. 2006 Nov;5(11):2815-23.

40.

Regulatory effects of mammalian target of rapamycin-activated pathways in type I and II interferon signaling.

Kaur S, Lal L, Sassano A, Majchrzak-Kita B, Srikanth M, Baker DP, Petroulakis E, Hay N, Sonenberg N, Fish EN, Platanias LC.

J Biol Chem. 2007 Jan 19;282(3):1757-68. Epub 2006 Nov 17.

41.

Role of the p38 mitogen-activated protein kinase pathway in the generation of arsenic trioxide-dependent cellular responses.

Giafis N, Katsoulidis E, Sassano A, Tallman MS, Higgins LS, Nebreda AR, Davis RJ, Platanias LC.

Cancer Res. 2006 Jul 1;66(13):6763-71.

42.

Vaccinia virus activation of CCR5 invokes tyrosine phosphorylation signaling events that support virus replication.

Rahbar R, Murooka TT, Hinek AA, Galligan CL, Sassano A, Yu C, Srivastava K, Platanias LC, Fish EN.

J Virol. 2006 Jul;80(14):7245-59.

43.

Recombinant human uteroglobin/CC10 inhibits the adhesion and migration of primary human endothelial cells via specific and saturable binding to fibronectin.

Antico G, Lingen MW, Sassano A, Melby J, Welch RW, Fiore S, Pilon AL, Miele L.

J Cell Physiol. 2006 May;207(2):553-61.

PMID:
16453303
44.

Role of the p38 mitogen-activated protein kinase pathway in cytokine-mediated hematopoietic suppression in myelodysplastic syndromes.

Katsoulidis E, Li Y, Yoon P, Sassano A, Altman J, Kannan-Thulasiraman P, Balasubramanian L, Parmar S, Varga J, Tallman MS, Verma A, Platanias LC.

Cancer Res. 2005 Oct 1;65(19):9029-37.

45.

Mitogen-activated protein kinase pathways in interferon signaling.

Sassano A, Verma A, Platanias LC.

Methods Mol Med. 2005;116:135-50.

PMID:
16000859
46.

Role of protein kinase C-delta (PKC-delta) in the generation of the effects of IFN-alpha in chronic myelogenous leukemia cells.

Kaur S, Parmar S, Smith J, Katsoulidis E, Li Y, Sassano A, Majchrzak B, Uddin S, Tallman MS, Fish EN, Platanias LC.

Exp Hematol. 2005 May;33(5):550-7.

PMID:
15850832
47.

Differential regulation of the p70 S6 kinase pathway by interferon alpha (IFNalpha) and imatinib mesylate (STI571) in chronic myelogenous leukemia cells.

Parmar S, Smith J, Sassano A, Uddin S, Katsoulidis E, Majchrzak B, Kambhampati S, Eklund EA, Tallman MS, Fish EN, Platanias LC.

Blood. 2005 Oct 1;106(7):2436-43. Epub 2005 Mar 24.

48.

Activation of mitogen-activated protein kinase kinase (MKK) 3 and MKK6 by type I interferons.

Li Y, Batra S, Sassano A, Majchrzak B, Levy DE, Gaestel M, Fish EN, Davis RJ, Platanias LC.

J Biol Chem. 2005 Mar 18;280(11):10001-10. Epub 2005 Jan 11. Erratum in: J Biol Chem. 2006 Apr 14;281(15):10651.

49.

EVI1 abrogates interferon-alpha response by selectively blocking PML induction.

Buonamici S, Li D, Mikhail FM, Sassano A, Platanias LC, Colamonici O, Anastasi J, Nucifora G.

J Biol Chem. 2005 Jan 7;280(1):428-36. Epub 2004 Nov 1.

50.

Signalling pathways activated by all-trans-retinoic acid in acute promyelocytic leukemia cells.

Kambhampati S, Verma A, Li Y, Parmar S, Sassano A, Platanias LC.

Leuk Lymphoma. 2004 Nov;45(11):2175-85. Review.

PMID:
15512805

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