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Items: 1 to 50 of 70

1.

Functional characterisation of ClpP mutations conferring resistance to acyldepsipeptide antibiotics in Firmicutes.

Malik IT, Pereira R, Vielberg MT, Mayer C, Straetener J, Thomy D, Famulla K, Castro H, Sass P, Groll M, Brötz-Oesterhelt H.

Chembiochem. 2020 Mar 17. doi: 10.1002/cbic.201900787. [Epub ahead of print]

PMID:
32181548
2.

Magnetic Imaging of Domain Walls in the Antiferromagnetic Topological Insulator MnBi2Te4.

Sass PM, Ge W, Yan J, Obeysekera D, Yang JJ, Wu W.

Nano Lett. 2020 Mar 5. doi: 10.1021/acs.nanolett.0c00114. [Epub ahead of print]

PMID:
32119560
3.

The functional ClpXP protease of Chlamydia trachomatis requires distinct clpP genes from separate genetic loci.

Pan S, Malik IT, Thomy D, Henrichfreise B, Sass P.

Sci Rep. 2019 Oct 1;9(1):14129. doi: 10.1038/s41598-019-50505-5.

4.

Staphylococcus aureus Lpl protein triggers human host cell invasion via activation of Hsp90 receptor.

Tribelli PM, Luqman A, Nguyen MT, Madlung J, Fan SH, Macek B, Sass P, Bitschar K, Schittek B, Kretschmer D, Götz F.

Cell Microbiol. 2020 Jan;22(1):e13111. doi: 10.1111/cmi.13111. Epub 2019 Sep 13.

PMID:
31515903
5.

The ADEP Biosynthetic Gene Cluster in Streptomyces hawaiiensis NRRL 15010 Reveals an Accessory clpP Gene as a Novel Antibiotic Resistance Factor.

Thomy D, Culp E, Adamek M, Cheng EY, Ziemert N, Wright GD, Sass P, Brötz-Oesterhelt H.

Appl Environ Microbiol. 2019 Oct 1;85(20). pii: e01292-19. doi: 10.1128/AEM.01292-19. Print 2019 Oct 15.

6.

Consequences of dosing and timing on the antibacterial effects of ADEP antibiotics.

Mayer C, Sass P, Brötz-Oesterhelt H.

Int J Med Microbiol. 2019 Nov;309(7):151329. doi: 10.1016/j.ijmm.2019.151329. Epub 2019 Jul 14.

PMID:
31331697
7.

Epigenetic inhibitor zebularine activates ear pinna wound closure in the mouse.

Sass P, Sosnowski P, Podolak-Popinigis J, Górnikiewicz B, Kamińska J, Deptuła M, Nowicka E, Wardowska A, Ruczyński J, Rekowski P, Rogujski P, Filipowicz N, Mieczkowska A, Peszyńska-Sularz G, Janus Ł, Skowron P, Czupryn A, Mucha P, Piotrowski A, Rodziewicz-Motowidło S, Pikuła M, Sachadyn P.

EBioMedicine. 2019 Aug;46:317-329. doi: 10.1016/j.ebiom.2019.07.010. Epub 2019 Jul 11.

8.

A new host cell internalisation pathway for SadA-expressing staphylococci triggered by excreted neurochemicals.

Luqman A, Ebner P, Reichert S, Sass P, Kabagema-Bilan C, Heilmann C, Ruth P, Götz F.

Cell Microbiol. 2019 Sep;21(9):e13044. doi: 10.1111/cmi.13044. Epub 2019 Jun 7.

9.

The Polycyclic Polyprenylated Acylphloroglucinol Antibiotic PPAP 23 Targets the Membrane and Iron Metabolism in Staphylococcus aureus.

Wang H, Kraus F, Popella P, Baykal A, Guttroff C, François P, Sass P, Plietker B, Götz F.

Front Microbiol. 2019 Jan 22;10:14. doi: 10.3389/fmicb.2019.00014. eCollection 2019.

10.

Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus.

Reichert S, Ebner P, Bonetti EJ, Luqman A, Nega M, Schrenzel J, Spröer C, Bunk B, Overmann J, Sass P, François P, Götz F.

Front Microbiol. 2018 Jul 12;9:1539. doi: 10.3389/fmicb.2018.01539. eCollection 2018.

11.

Transcriptional profile of in vitro expanded human epidermal progenitor cells for the treatment of non-healing wounds.

Langa P, Wardowska A, Zieliński J, Podolak-Popinigis J, Sass P, Sosnowski P, Kondej K, Renkielska A, Sachadyn P, Trzonkowski P, Pikuła M.

J Dermatol Sci. 2018 Mar;89(3):272-281. doi: 10.1016/j.jdermsci.2017.12.003. Epub 2017 Dec 13.

PMID:
29287803
12.

A highly asynchronous developmental program triggered during germination of dormant akinetes of filamentous diazotrophic cyanobacteria.

Perez R, Wörmer L, Sass P, Maldener I.

FEMS Microbiol Ecol. 2018 Jan 1;94(1). doi: 10.1093/femsec/fix131.

PMID:
29228342
13.

Transcriptomic responses to wounding: meta-analysis of gene expression microarray data.

Sass PA, Dąbrowski M, Charzyńska A, Sachadyn P.

BMC Genomics. 2017 Nov 7;18(1):850. doi: 10.1186/s12864-017-4202-8.

14.

Characteristics of Interim Deans at U.S. Medical Schools: Implications for Institutions and Individuals.

Bunton SA, Sass P, Sloane RA, Grigsby RK.

Acad Med. 2018 Feb;93(2):241-245. doi: 10.1097/ACM.0000000000001920.

PMID:
28906262
15.

Erratum.

Sass P.

Methods Mol Biol. 2017;1520:E1-E3. doi: 10.1007/978-1-4939-6634-9_21. No abstract available.

PMID:
28265830
16.

The cell wall precursor lipid II acts as a molecular signal for the Ser/Thr kinase PknB of Staphylococcus aureus.

Hardt P, Engels I, Rausch M, Gajdiss M, Ulm H, Sass P, Ohlsen K, Sahl HG, Bierbaum G, Schneider T, Grein F.

Int J Med Microbiol. 2017 Jan;307(1):1-10. doi: 10.1016/j.ijmm.2016.12.001. Epub 2016 Dec 12.

PMID:
27989665
17.

Antibiotics: Precious Goods in Changing Times.

Sass P.

Methods Mol Biol. 2017;1520:3-22. doi: 10.1007/978-1-4939-6634-9_1. Review.

PMID:
27873243
18.

Acyldepsipeptide antibiotics kill mycobacteria by preventing the physiological functions of the ClpP1P2 protease.

Famulla K, Sass P, Malik I, Akopian T, Kandror O, Alber M, Hinzen B, Ruebsamen-Schaeff H, Kalscheuer R, Goldberg AL, Brötz-Oesterhelt H.

Mol Microbiol. 2016 Jul;101(2):194-209. doi: 10.1111/mmi.13362. Epub 2016 Apr 1.

19.

Use of a stable-isotope-labeled reporter peptide and antioxidants for reliable quantification of methionine oxidation in a monoclonal antibody by liquid chromatography/mass spectrometry.

Kang P, Mezhebovsky T, Chen W, McCardle JA, Zhang S, Sullivan EP, Sass PM, Routhier E.

Rapid Commun Mass Spectrom. 2016 Jul 30;30(14):1734-1742. doi: 10.1002/rcm.7646.

PMID:
28328036
20.

Variable-Temperature Tip-Enhanced Raman Spectroscopy of Single-Molecule Fluctuations and Dynamics.

Park KD, Muller EA, Kravtsov V, Sass PM, Dreyer J, Atkin JM, Raschke MB.

Nano Lett. 2016 Jan 13;16(1):479-87. doi: 10.1021/acs.nanolett.5b04135. Epub 2015 Dec 28.

PMID:
26679007
21.

Nanoscale probing of dynamics in local molecular environments.

Atkin JM, Sass PM, Teichen PE, Eaves JD, Raschke MB.

J Phys Chem Lett. 2015 Nov 19;6(22):4616-21. doi: 10.1021/acs.jpclett.5b02093. Epub 2015 Nov 9.

PMID:
26528865
22.

AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control.

Gersch M, Famulla K, Dahmen M, Göbl C, Malik I, Richter K, Korotkov VS, Sass P, Rübsamen-Schaeff H, Madl T, Brötz-Oesterhelt H, Sieber SA.

Nat Commun. 2015 Feb 19;6:6320. doi: 10.1038/ncomms7320.

PMID:
25695750
23.

Generation of a vancomycin-intermediate Staphylococcus aureus (VISA) strain by two amino acid exchanges in VraS.

Berscheid A, François P, Strittmatter A, Gottschalk G, Schrenzel J, Sass P, Bierbaum G.

J Antimicrob Chemother. 2014 Dec;69(12):3190-8. doi: 10.1093/jac/dku297. Epub 2014 Aug 6.

PMID:
25103491
24.

Bacterial caseinolytic proteases as novel targets for antibacterial treatment.

Brötz-Oesterhelt H, Sass P.

Int J Med Microbiol. 2014 Jan;304(1):23-30. doi: 10.1016/j.ijmm.2013.09.001. Epub 2013 Sep 4. Review.

PMID:
24119566
25.

Bacterial cell division as a target for new antibiotics.

Sass P, Brötz-Oesterhelt H.

Curr Opin Microbiol. 2013 Oct;16(5):522-30. doi: 10.1016/j.mib.2013.07.006. Epub 2013 Aug 8. Review.

PMID:
23932516
26.

Atropisomeric dihydroanthracenones as inhibitors of multiresistant Staphylococcus aureus.

Bara R, Zerfass I, Aly AH, Goldbach-Gecke H, Raghavan V, Sass P, Mándi A, Wray V, Polavarapu PL, Pretsch A, Lin W, Kurtán T, Debbab A, Brötz-Oesterhelt H, Proksch P.

J Med Chem. 2013 Apr 25;56(8):3257-72. doi: 10.1021/jm301816a. Epub 2013 Apr 16.

PMID:
23534483
27.

Genome sequence of Staphylococcus aureus VC40, a vancomycin- and daptomycin-resistant strain, to study the genetics of development of resistance to currently applied last-resort antibiotics.

Sass P, Berscheid A, Jansen A, Oedenkoven M, Szekat C, Strittmatter A, Gottschalk G, Bierbaum G.

J Bacteriol. 2012 Apr;194(8):2107-8. doi: 10.1128/JB.06631-11.

28.

Revisiting the genomes of the Staphylococcus aureus strains NCTC 8325 and RN4220.

Berscheid A, Sass P, Weber-Lassalle K, Cheung AL, Bierbaum G.

Int J Med Microbiol. 2012 Mar;302(2):84-7. doi: 10.1016/j.ijmm.2012.01.002. Epub 2012 Mar 12.

PMID:
22417616
29.

Antibiotic acyldepsipeptides activate ClpP peptidase to degrade the cell division protein FtsZ.

Sass P, Josten M, Famulla K, Schiffer G, Sahl HG, Hamoen L, Brötz-Oesterhelt H.

Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17474-9. doi: 10.1073/pnas.1110385108. Epub 2011 Oct 3.

30.

Bridging charge-orbital ordering and Fermi surface instabilities in half-doped single-layered manganite La(0.5)Sr(1.5)MnO₄.

Evtushinsky DV, Inosov DS, Urbanik G, Zabolotnyy VB, Schuster R, Sass P, Hänke T, Hess C, Büchner B, Follath R, Reutler P, Revcolevschi A, Kordyuk AA, Borisenko SV.

Phys Rev Lett. 2010 Oct 1;105(14):147201. Epub 2010 Sep 28.

PMID:
21230862
31.

Generation and characterization of high affinity human monoclonal antibodies that neutralize staphylococcal enterotoxin B.

Drozdowski B, Zhou Y, Kline B, Spidel J, Chan YY, Albone E, Turchin H, Chao Q, Henry M, Balogach J, Routhier E, Bavari S, Nicolaides NC, Sass PM, Grasso L.

J Immune Based Ther Vaccines. 2010 Dec 21;8:9. doi: 10.1186/1476-8518-8-9.

32.

Postgenomic strategies in antibacterial drug discovery.

Brötz-Oesterhelt H, Sass P.

Future Microbiol. 2010 Oct;5(10):1553-79. doi: 10.2217/fmb.10.119. Review.

33.

Advances in targeted therapeutic agents.

Nicolaides NC, Sass PM, Grasso L.

Expert Opin Drug Discov. 2010 Nov;5(11):1123-40. doi: 10.1517/17460441.2010.521496. Epub 2010 Oct 1. Review.

PMID:
22827748
34.

Endosialin/TEM-1/CD248 regulates pericyte proliferation through PDGF receptor signaling.

Tomkowicz B, Rybinski K, Sebeck D, Sass P, Nicolaides NC, Grasso L, Zhou Y.

Cancer Biol Ther. 2010 Jun 1;9(11):908-15. Epub 2010 Jun 8.

PMID:
20484976
35.

Native graS mutation supports the susceptibility of Staphylococcus aureus strain SG511 to antimicrobial peptides.

Sass P, Bierbaum G.

Int J Med Microbiol. 2009 Jun;299(5):313-22. doi: 10.1016/j.ijmm.2008.10.005. Epub 2009 Jan 9.

PMID:
19138560
36.

The lantibiotic mersacidin is a strong inducer of the cell wall stress response of Staphylococcus aureus.

Sass P, Jansen A, Szekat C, Sass V, Sahl HG, Bierbaum G.

BMC Microbiol. 2008 Oct 23;8:186. doi: 10.1186/1471-2180-8-186.

37.

Preclinical evaluation of MORAb-009, a chimeric antibody targeting tumor-associated mesothelin.

Hassan R, Ebel W, Routhier EL, Patel R, Kline JB, Zhang J, Chao Q, Jacob S, Turchin H, Gibbs L, Phillips MD, Mudali S, Iacobuzio-Donahue C, Jaffee EM, Moreno M, Pastan I, Sass PM, Nicolaides NC, Grasso L.

Cancer Immun. 2007 Dec 19;7:20.

38.

Developing novel biopharmaceutical products through morphogenics.

Nicolaides NC, Sass PM, Chao Q, Kline JB, Ebel W, Routhier E, Zhou Y, Grasso L.

Expert Opin Drug Discov. 2007 Dec;2(12):1619-29. doi: 10.1517/17460441.2.12.1619.

PMID:
23488905
39.

Interaction of endosialin/TEM1 with extracellular matrix proteins mediates cell adhesion and migration.

Tomkowicz B, Rybinski K, Foley B, Ebel W, Kline B, Routhier E, Sass P, Nicolaides NC, Grasso L, Zhou Y.

Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):17965-70. Epub 2007 Nov 6.

40.

Preclinical evaluation of MORAb-003, a humanized monoclonal antibody antagonizing folate receptor-alpha.

Ebel W, Routhier EL, Foley B, Jacob S, McDonough JM, Patel RK, Turchin HA, Chao Q, Kline JB, Old LJ, Phillips MD, Nicolaides NC, Sass PM, Grasso L.

Cancer Immun. 2007 Mar 9;7:6.

41.

Rapid generation of plant traits via regulation of DNA mismatch repair.

Chao Q, Sullivan CD, Getz JM, Gleason KB, Sass PM, Nicolaides NC, Grasso L.

Plant Biotechnol J. 2005 Jul;3(4):399-407.

42.
43.

Human antibodies for immunotherapy development generated via a human B cell hybridoma technology.

Li J, Sai T, Berger M, Chao Q, Davidson D, Deshmukh G, Drozdowski B, Ebel W, Harley S, Henry M, Jacob S, Kline B, Lazo E, Rotella F, Routhier E, Rudolph K, Sage J, Simon P, Yao J, Zhou Y, Kavuru M, Bonfield T, Thomassen MJ, Sass PM, Nicolaides NC, Grasso L.

Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3557-62. Epub 2006 Feb 27.

44.

Morphogenics as a tool for target discovery and drug development.

Nicolaides NC, Ebel W, Kline B, Chao Q, Routhier E, Sass PM, Grasso L.

Ann N Y Acad Sci. 2005 Nov;1059:86-96. Review.

PMID:
16382047
45.

Lower extremity abnormalities in children.

Sass P, Hassan G.

Am Fam Physician. 2003 Aug 1;68(3):461-8. Review. Erratum in: Am Fam Physician. 2004 Mar 1;69(5):1049.

46.

Recognizing spinal cord emergencies.

Arce D, Sass P, Abul-Khoudoud H.

Am Fam Physician. 2001 Aug 15;64(4):631-8. Review. Erratum in: Am Fam Physician 2002 May 1;65(9):1751.

47.

Teaching community health assessment skills in a problem-based format.

Sass P, Edelsack P.

Acad Med. 2001 Jan;76(1):88-91.

PMID:
11154203
48.

Antimicrobial peptides: structure, function and therapeutic potential.

Sass PM.

Curr Opin Drug Discov Devel. 2000 Sep;3(5):646-54.

PMID:
19649893
50.

The involvement of selectins in cell adhesion, tumor progression, and metastasis.

Sass PM.

Cancer Invest. 1998;16(5):322-8. Review. No abstract available.

PMID:
9627680

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