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Items: 1 to 50 of 222

1.

Reduced adolescent risk-assessment and lower nicotinic beta-2 expression in rats exposed to nicotine through lactation by forcedly drinking dams.

Faure A, Zoratto F, Chirico D, Romano E, Mancinelli R, Saso L, Callebert J, Laviola G, Granon S, Adriani W.

Neuroscience. 2019 Jun 19;413:64-76. doi: 10.1016/j.neuroscience.2019.06.014. [Epub ahead of print]

PMID:
31228592
2.

Renoprotective effect of tectorigenin glycosides isolated from Iris spuria L. (Zeal) against hyperoxaluria and hyperglycemia in NRK-49Fcells.

Divya G, Albert A, Singab ANB, Ayoub IM, Al-Sayed E, Paul E, Manoharan K, Saso L, Selvam GS.

Nat Prod Res. 2019 May 28:1-6. doi: 10.1080/14786419.2019.1613396. [Epub ahead of print]

PMID:
31135219
3.

Topology-Dependent Dissociation Mode of the O-H Bond in Monohydroxycoumarins.

Velkov Z, Traykov M, Trenchev I, Saso L, Tadjer A.

J Phys Chem A. 2019 Jun 20;123(24):5106-5113. doi: 10.1021/acs.jpca.9b00535. Epub 2019 Jun 7.

PMID:
31117481
4.

Potential Applications of NRF2 Inhibitors in Cancer Therapy.

Panieri E, Saso L.

Oxid Med Cell Longev. 2019 Apr 11;2019:8592348. doi: 10.1155/2019/8592348. eCollection 2019. Review.

5.

Role of c-MET Inhibitors in Overcoming Drug Resistance in Spheroid Models of Primary Human Pancreatic Cancer and Stellate Cells.

Firuzi O, Che PP, El Hassouni B, Buijs M, Coppola S, Löhr M, Funel N, Heuchel R, Carnevale I, Schmidt T, Mantini G, Avan A, Saso L, Peters GJ, Giovannetti E.

Cancers (Basel). 2019 May 8;11(5). pii: E638. doi: 10.3390/cancers11050638.

6.

Pharmacological Applications of Nrf2 Inhibitors as Potential Antineoplastic Drugs.

Telkoparan-Akillilar P, Suzen S, Saso L.

Int J Mol Sci. 2019 Apr 24;20(8). pii: E2025. doi: 10.3390/ijms20082025. Review.

7.

Systems Approach to Identify Common Genes and Pathways Associated with Response to Selective Serotonin Reuptake Inhibitors and Major Depression Risk.

Srivastava A, Singh P, Gupta H, Kaur H, Kanojia N, Guin D, Sood M, Chadda RK, Yadav J, Vohora D, Saso L, Kukreti R.

Int J Mol Sci. 2019 Apr 23;20(8). pii: E1993. doi: 10.3390/ijms20081993.

8.

Oxidative Stress: A Key Modulator in Neurodegenerative Diseases.

Singh A, Kukreti R, Saso L, Kukreti S.

Molecules. 2019 Apr 22;24(8). pii: E1583. doi: 10.3390/molecules24081583. Review.

9.

Regulation of the Nrf2 Pathway by Glycogen Synthase Kinase-3β in MPP⁺-Induced Cell Damage.

Armagan G, Sevgili E, Gürkan FT, Köse FA, Bilgiç T, Dagcı T, Saso L.

Molecules. 2019 Apr 8;24(7). pii: E1377. doi: 10.3390/molecules24071377.

10.

Antioxidant Activities of Alkyl Substituted Pyrazine Derivatives of Chalcones-In Vitro and In Silico Study.

Stepanić V, Matijašić M, Horvat T, Verbanac D, Kučerová-Chlupáčová M, Saso L, Žarković N.

Antioxidants (Basel). 2019 Apr 5;8(4). pii: E90. doi: 10.3390/antiox8040090.

11.

Critical reflections, challenges and solutions for migrant and refugee health: 2nd M8 Alliance Expert Meeting.

Bempong NE, Sheath D, Seybold J, Flahault A, Depoux A, Saso L.

Public Health Rev. 2019 Mar 19;40:3. doi: 10.1186/s40985-019-0113-3. eCollection 2019.

12.

Relation of Redox and Structural Alterations of Rat Skin in the Function of Chronological Aging.

Jankovic A, Saso L, Korac A, Korac B.

Oxid Med Cell Longev. 2019 Feb 14;2019:2471312. doi: 10.1155/2019/2471312. eCollection 2019.

13.

Synthesis and Characterization of 3-(1-((3,4-Dihydroxyphenethyl)amino)ethylidene)-chroman-2,4-dione as a Potential Antitumor Agent.

Dimić DS, Marković ZS, Saso L, Avdović EH, Đorović JR, Petrović IP, Stanisavljević DD, Stevanović MJ, Potočňák I, Samoľová E, Trifunović SR, Dimitrić Marković JM.

Oxid Med Cell Longev. 2019 Feb 13;2019:2069250. doi: 10.1155/2019/2069250. eCollection 2019.

14.

The effects of trifluoromethylated derivatives on prostaglandin E2 and thromboxane A2 production in human leukemic U937 macrophages.

Beara I, Majkić T, Fioravanti S, Trulli L, Mimica-Dukić N, Pellacani L, Saso L.

Med Chem. 2019 Feb 8. doi: 10.2174/1573406415666190208150253. [Epub ahead of print]

PMID:
30734682
15.

The influence of alkaloids on oxidative stress and related signaling pathways.

Macáková K, Afonso R, Saso L, Mladěnka P.

Free Radic Biol Med. 2019 Apr;134:429-444. doi: 10.1016/j.freeradbiomed.2019.01.026. Epub 2019 Jan 29. Review.

PMID:
30703480
16.

Screening Pyridine Derivatives against Human Hydrogen Sulfide-synthesizing Enzymes by Orthogonal Methods.

Zuhra K, Sousa PMF, Paulini G, Lemos AR, Kalme Z, Bisenieks I, Bisenieks E, Vigante B, Duburs G, Bandeiras TM, Saso L, Giuffrè A, Vicente JB.

Sci Rep. 2019 Jan 24;9(1):684. doi: 10.1038/s41598-018-36994-w.

17.

Modulation of ERK1/2 and Akt Pathways Involved in the Neurotrophic Action of Caffeic Acid Alkyl Esters.

Hosseini R, Moosavi F, Silva T, Rajaian H, Hosseini SY, Bina S, Saso L, Miri R, Borges F, Firuzi O.

Molecules. 2018 Dec 17;23(12). pii: E3340. doi: 10.3390/molecules23123340.

18.

5-Oxo-hexahydroquinoline derivatives as modulators of P-gp, MRP1 and BCRP transporters to overcome multidrug resistance in cancer cells.

Ranjbar S, Khonkarn R, Moreno A, Baubichon-Cortay H, Miri R, Khoshneviszadeh M, Saso L, Edraki N, Falson P, Firuzi O.

Toxicol Appl Pharmacol. 2019 Jan 1;362:136-149. doi: 10.1016/j.taap.2018.10.025. Epub 2018 Nov 2.

PMID:
30391378
19.

Design and development of Nrf2 modulators for cancer chemoprevention and therapy: a review.

Sova M, Saso L.

Drug Des Devel Ther. 2018 Sep 25;12:3181-3197. doi: 10.2147/DDDT.S172612. eCollection 2018. Review.

20.

Tetrahydroquinolinone derivatives as potent P-glycoprotein inhibitors: design, synthesis, biological evaluation and molecular docking analysis.

Ranjbar S, Firuzi O, Edraki N, Shahraki O, Saso L, Khoshneviszadeh M, Miri R.

Medchemcomm. 2017 Aug 23;8(10):1919-1933. doi: 10.1039/c7md00178a. eCollection 2017 Oct 1.

21.

Oxidative Stress Induces HSP90 Upregulation on the Surface of Primary Human Endothelial Cells: Role of the Antioxidant 7,8-Dihydroxy-4-methylcoumarin in Preventing HSP90 Exposure to the Immune System.

Profumo E, Buttari B, Tinaburri L, D'Arcangelo D, Sorice M, Capozzi A, Garofalo T, Facchiano A, Businaro R, Kumar P, Singh BK, Parmar VS, Saso L, Riganò R.

Oxid Med Cell Longev. 2018 Apr 10;2018:2373167. doi: 10.1155/2018/2373167. eCollection 2018.

22.

Influence of Oxidative Stress on Catalytic and Non-glycolytic Functions of Glyceraldehyde-3-phosphate dehydrogenase.

Muronetz VI, Melnikova AK, Saso L, Schmalhausen EV.

Curr Med Chem. 2018 May 29. doi: 10.2174/0929867325666180530101057. [Epub ahead of print]

PMID:
29848267
23.

Nonylphenol and Octylphenol Differently Affect Cell Redox Balance by Modulating the Nitric Oxide Signaling.

Magnifico MC, Xhani M, Popov M, Saso L, Sarti P, Arese M.

Oxid Med Cell Longev. 2018 Apr 2;2018:1684827. doi: 10.1155/2018/1684827. eCollection 2018.

24.

Viral Induced Oxidative and Inflammatory Response in Alzheimer's Disease Pathogenesis with Identification of Potential Drug Candidates: A Systematic Review using Systems Biology Approach.

Talwar P, Gupta R, Kushwaha S, Agarwal R, Saso L, Kukreti S, Kukreti R.

Curr Neuropharmacol. 2019;17(4):352-365. doi: 10.2174/1570159X16666180419124508.

PMID:
29676229
25.

In vitro antioxidant activity of thiazolidinone derivatives of 1,3-thiazole and 1,3,4-thiadiazole.

Djukic M, Fesatidou M, Xenikakis I, Geronikaki A, Angelova VT, Savic V, Pasic M, Krilovic B, Djukic D, Gobeljic B, Pavlica M, Djuric A, Stanojevic I, Vojvodic D, Saso L.

Chem Biol Interact. 2018 Apr 25;286:119-131. doi: 10.1016/j.cbi.2018.03.013. Epub 2018 Mar 21.

PMID:
29574026
26.

Inhibition of Shiga toxin-converting bacteriophage development by novel antioxidant compounds.

Bloch S, Nejman-Faleńczyk B, Pierzynowska K, Piotrowska E, Węgrzyn A, Marminon C, Bouaziz Z, Nebois P, Jose J, Le Borgne M, Saso L, Węgrzyn G.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):639-650. doi: 10.1080/14756366.2018.1444610.

27.

Mono and dihydroxy coumarin derivatives: Copper chelation and reduction ability.

Catapano MC, Karlíčková J, Tvrdý V, Sharma S, Prasad AK, Saso L, Chhillar AK, Kuneš J, Pour M, Parmar VS, Mladěnka P.

J Trace Elem Med Biol. 2018 Mar;46:88-95. doi: 10.1016/j.jtemb.2017.11.014. Epub 2017 Nov 27.

PMID:
29413115
28.

Modulation of Oxidative Stress: Pharmaceutical and Pharmacological Aspects 2017.

Saso L, Korkina L, Zarkovic N.

Oxid Med Cell Longev. 2017;2017:4802824. doi: 10.1155/2017/4802824. Epub 2017 Dec 17. No abstract available.

29.

Protective effects of new antioxidant compositions of 4-methylcoumarins and related compounds with dl-α-tocopherol and l-ascorbic acid.

Kancheva VD, Slavova-Kazakova AK, Angelova SE, Kumar P, Malhotra S, Singh BK, Saso L, Prasad AK, Parmar VS.

J Sci Food Agric. 2018 Aug;98(10):3784-3794. doi: 10.1002/jsfa.8892. Epub 2018 Mar 15.

PMID:
29344958
30.

Efficient synthesis and first regioselective C-6 direct arylation of imidazo[2,1-c][1,2,4]triazine scaffold and their evaluation in H2O2-induced oxidative stress.

Loubidi M, Jouha J, Tber Z, Khouili M, Suzenet F, Akssira M, Erdogan MA, Köse FA, Dagcı T, Armagan G, Saso L, Guillaumet G.

Eur J Med Chem. 2018 Feb 10;145:113-123. doi: 10.1016/j.ejmech.2017.12.081. Epub 2017 Dec 27.

PMID:
29324335
31.

9-(4'-dimethylaminophenyl)-2,6,7-trihydroxy-xanthene-3-one is a Potentially Novel Antiplatelet Drug which Antagonizes the Effect of Thromboxane A2.

Applova L, Veljovic E, Muratovic S, Karlickova J, Macakova K, Zavrsnik D, Saso L, Duric K, Mladenka P.

Med Chem. 2018 Feb 6;14(2):200-209. doi: 10.2174/1573406413666171010102535.

PMID:
29032760
32.

In Vitro Assessment of the Effect of Antiepileptic Drugs on Expression and Function of ABC Transporters and Their Interactions with ABCC2.

Grewal GK, Kukal S, Kanojia N, Madan K, Saso L, Kukreti R.

Molecules. 2017 Sep 29;22(10). pii: E1484. doi: 10.3390/molecules22101484.

33.

Protective effects of 4-methylcoumarins and related compounds as radical scavengers and chain-breaking antioxidants.

Kancheva VD, Slavova-Kazakova AK, Angelova SE, Singh SK, Malhotra S, Singh BK, Saso L, Prasad AK, Parmar VS.

Biochimie. 2017 Sep;140:133-145. doi: 10.1016/j.biochi.2017.07.010. Epub 2017 Jul 25.

PMID:
28751215
34.

Long Chain Alkyl Esters of Hydroxycinnamic Acids as Promising Anticancer Agents: Selective Induction of Apoptosis in Cancer Cells.

Menezes JCJMDS, Edraki N, Kamat SP, Khoshneviszadeh M, Kayani Z, Mirzaei HH, Miri R, Erfani N, Nejati M, Cavaleiro JAS, Silva T, Saso L, Borges F, Firuzi O.

J Agric Food Chem. 2017 Aug 23;65(33):7228-7239. doi: 10.1021/acs.jafc.7b01388. Epub 2017 Aug 8.

PMID:
28718636
35.

The Role of Oxidative Stress Modulators in Breast Cancer.

Gurer-Orhan H, Ince E, Konyar D, Saso L, Suzen S.

Curr Med Chem. 2018;25(33):4084-4101. doi: 10.2174/0929867324666170711114336. Review.

PMID:
28699501
36.

Antioxidant activity of phenolic compounds from extracts of Eucalyptus globulus and Melaleuca styphelioides and their protective role on D-glucose-induced hyperglycemic stress and oxalate stress in NRK-49Fcells.

Ganesan D, Al-Sayed E, Albert A, Paul E, Singab ANB, Govindan Sadasivam S, Saso L.

Nat Prod Res. 2018 Jun;32(11):1274-1280. doi: 10.1080/14786419.2017.1343324. Epub 2017 Jun 21.

PMID:
28637361
37.

Cardiovascular Mitochondrial Dysfunction Induced by Cocaine: Biomarkers and Possible Beneficial Effects of Modulators of Oxidative Stress.

Graziani M, Sarti P, Arese M, Magnifico MC, Badiani A, Saso L.

Oxid Med Cell Longev. 2017;2017:3034245. doi: 10.1155/2017/3034245. Epub 2017 May 16. Review.

38.

Derivatives of caffeic acid, a natural antioxidant, as the basis for the discovery of novel nonpeptidic neurotrophic agents.

Moosavi F, Hosseini R, Rajaian H, Silva T, Magalhães E Silva D, Saso L, Edraki N, Miri R, Borges F, Firuzi O.

Bioorg Med Chem. 2017 Jun 15;25(12):3235-3246. doi: 10.1016/j.bmc.2017.04.026. Epub 2017 Apr 27.

PMID:
28495385
39.

Potential Use of Modulators of Oxidative Stress as Add-on Therapy in Patients with Anxiety Disorders.

Boldrini P, Fusco A, Nicoletti F, Badiani A, Saso L.

Curr Drug Targets. 2018;19(6):636-650. doi: 10.2174/1389450118666170425153356.

PMID:
28443504
40.

Controversy about pharmacological modulation of Nrf2 for cancer therapy.

Milkovic L, Zarkovic N, Saso L.

Redox Biol. 2017 Aug;12:727-732. doi: 10.1016/j.redox.2017.04.013. Epub 2017 Apr 8. Review.

41.

Corrigendum to The Competence of 7,8-Diacetoxy-4-Methylcoumarin and Other Polyphenolic Acetates in Mitigating the Oxidative Stress and their Role in Angiogenesis.

Joshi R, Rohil V, Arora S, Manral S, Kumar A, Goel S, Priya N, Singh P, Ponnan P, Chatterji S, Dwarakanath BS, Saluja D, Rawat DS, Prasad AK, Saso L, Kohli E, DePass AL, Bracke ME, Parmar VS, Raj HG.

Curr Top Med Chem. 2017;17(9):1115. doi: 10.2174/156802661709170213214101.

PMID:
28406076
42.

Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer's disease and Parkinson's disease.

Ganguly G, Chakrabarti S, Chatterjee U, Saso L.

Drug Des Devel Ther. 2017 Mar 16;11:797-810. doi: 10.2147/DDDT.S130514. eCollection 2017. Review.

43.

Effect of Oxidative Stress on ABC Transporters: Contribution to Epilepsy Pharmacoresistance.

Grewal GK, Kukal S, Kanojia N, Saso L, Kukreti S, Kukreti R.

Molecules. 2017 Feb 27;22(3). pii: E365. doi: 10.3390/molecules22030365. Review.

44.

Novel 5-oxo-hexahydroquinoline derivatives: design, synthesis, in vitro P-glycoprotein-mediated multidrug resistance reversal profile and molecular dynamics simulation study.

Shahraki O, Edraki N, Khoshneviszadeh M, Zargari F, Ranjbar S, Saso L, Firuzi O, Miri R.

Drug Des Devel Ther. 2017 Feb 14;11:407-418. doi: 10.2147/DDDT.S119995. eCollection 2017.

45.

Synthesis of new heterocyclic compounds based on pyrazolopyridine scaffold and evaluation of their neuroprotective potential in MPP+-induced neurodegeneration.

Jouha J, Loubidi M, Bouali J, Hamri S, Hafid A, Suzenet F, Guillaumet G, Dagcı T, Khouili M, Aydın F, Saso L, Armagan G.

Eur J Med Chem. 2017 Mar 31;129:41-52. doi: 10.1016/j.ejmech.2017.02.019. Epub 2017 Feb 11.

PMID:
28214632
46.

Expression of heterologous oxalate decarboxylase in HEK293 cells confers protection against oxalate induced oxidative stress as a therapeutic approach for calcium oxalate stone disease.

Albert A, Tiwari V, Paul E, Ganesan D, Ayyavu M, Kujur R, Ponnusamy S, Shanmugam K, Saso L, Govindan Sadasivam S.

J Enzyme Inhib Med Chem. 2017 Dec;32(1):426-433. doi: 10.1080/14756366.2016.1256884.

47.

Detection of Reactive Oxygen and Nitrogen Species by Electron Paramagnetic Resonance (EPR) Technique.

Suzen S, Gurer-Orhan H, Saso L.

Molecules. 2017 Jan 21;22(1). pii: E181. doi: 10.3390/molecules22010181. Review.

48.

Disulfiram moderately restores impaired hepatic redox status of rats subchronically exposed to cadmium.

Begic A, Djuric A, Ninkovic M, Stevanovic I, Djurdjevic D, Pavlovic M, Jelic K, Pantelic A, Zebic G, Dejanovic B, Stanojevic I, Vojvodic D, Milosavljevic P, Djukic M, Saso L.

J Enzyme Inhib Med Chem. 2017 Dec;32(1):478-489. doi: 10.1080/14756366.2016.1261132.

49.

Antimycobacterial activity of novel hydrazide-hydrazone derivatives with 2H-chromene and coumarin scaffold.

Angelova VT, Valcheva V, Vassilev NG, Buyukliev R, Momekov G, Dimitrov I, Saso L, Djukic M, Shivachev B.

Bioorg Med Chem Lett. 2017 Jan 15;27(2):223-227. doi: 10.1016/j.bmcl.2016.11.071. Epub 2016 Nov 25.

PMID:
27914798
50.

Effect of organic co-solvents in the evaluation of the hydroxyl radical scavenging activity by the 2-deoxyribose degradation assay: The paradigmatic case of α-lipoic acid.

Brizzolari A, Campisi GM, Santaniello E, Razzaghi-Asl N, Saso L, Foti MC.

Biophys Chem. 2017 Jan;220:1-6. doi: 10.1016/j.bpc.2016.10.005. Epub 2016 Oct 31.

PMID:
27825024

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