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Items: 28

1.

Actin exposure upon tissue injury is a targetable wound site-specific protein marker.

Pendleton ED, Sullivan CJ, Sasmor HH, Bruse KD, Mayfield TB, Valente DL, Abrams RE, Griffey RH, Dresios J.

Biochem Biophys Rep. 2016 May 18;7:56-62. doi: 10.1016/j.bbrep.2016.05.013. eCollection 2016 Sep.

2.

A cell-free expression and purification process for rapid production of protein biologics.

Sullivan CJ, Pendleton ED, Sasmor HH, Hicks WL, Farnum JB, Muto M, Amendt EM, Schoborg JA, Martin RW, Clark LG, Anderson MJ, Choudhury A, Fior R, Lo YH, Griffey RH, Chappell SA, Jewett MC, Mauro VP, Dresios J.

Biotechnol J. 2016 Feb;11(2):238-48. doi: 10.1002/biot.201500214. Epub 2015 Dec 7.

PMID:
26427345
3.

Pharmacokinetics of a tumor necrosis factor-alpha phosphorothioate 2'-O-(2-methoxyethyl) modified antisense oligonucleotide: comparison across species.

Geary RS, Yu RZ, Watanabe T, Henry SP, Hardee GE, Chappell A, Matson J, Sasmor H, Cummins L, Levin AA.

Drug Metab Dispos. 2003 Nov;31(11):1419-28.

PMID:
14570775
4.

Evaluation of C-5 propynyl pyrimidine-containing oligonucleotides in vitro and in vivo.

Shen L, Siwkowski A, Wancewicz EV, Lesnik E, Butler M, Witchell D, Vasquez G, Ross B, Acevedo O, Inamati G, Sasmor H, Manoharan M, Monia BP.

Antisense Nucleic Acid Drug Dev. 2003;13(3):129-42.

PMID:
12954113
5.

Absolute bioavailability of 2'-O-(2-methoxyethyl)-modified antisense oligonucleotides following intraduodenal instillation in rats.

Geary RS, Khatsenko O, Bunker K, Crooke R, Moore M, Burckin T, Truong L, Sasmor H, Levin AA.

J Pharmacol Exp Ther. 2001 Mar;296(3):898-904.

PMID:
11181922
6.

Pharmacokinetic properties of 2'-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats.

Geary RS, Watanabe TA, Truong L, Freier S, Lesnik EA, Sioufi NB, Sasmor H, Manoharan M, Levin AA.

J Pharmacol Exp Ther. 2001 Mar;296(3):890-7.

PMID:
11181921
7.

Influence of diastereomeric ratios of deoxyribonucleoside phosphoramidites on the synthesis of phosphorothioate oligonucleotides.

Cheruvallath ZS, Sasmor H, Cole DL, Ravikumar VT.

Nucleosides Nucleotides Nucleic Acids. 2000 Mar;19(3):533-43.

PMID:
10843490
8.

Absorption of antisense oligonucleotides in rat intestine: effect of chemistry and length.

Khatsenko O, Morgan R, Truong L, York-Defalco C, Sasmor H, Conklin B, Geary RS.

Antisense Nucleic Acid Drug Dev. 2000 Feb;10(1):35-44.

PMID:
10726659
9.

Multiplexed screening of neutral mass-tagged RNA targets against ligand libraries with electrospray ionization FTICR MS: a paradigm for high-throughput affinity screening.

Hofstadler SA, Sannes-Lowery KA, Crooke ST, Ecker DJ, Sasmor H, Manalili S, Griffey RH.

Anal Chem. 1999 Aug 15;71(16):3436-40.

PMID:
10464476
10.

Oligonucleotide-europium complex conjugate designed to cleave the 5' cap structure of the ICAM-1 transcript potentiates antisense activity in cells.

Baker BF, Lot SS, Kringel J, Cheng-Flournoy S, Villiet P, Sasmor HM, Siwkowski AM, Chappell LL, Morrow JR.

Nucleic Acids Res. 1999 Mar 15;27(6):1547-51.

11.

Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression.

McKay RA, Miraglia LJ, Cummins LL, Owens SR, Sasmor H, Dean NM.

J Biol Chem. 1999 Jan 15;274(3):1715-22.

14.

Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo.

Monia BP, Sasmor H, Johnston JF, Freier SM, Lesnik EA, Muller M, Geiger T, Altmann KH, Moser H, Fabbro D.

Proc Natl Acad Sci U S A. 1996 Dec 24;93(26):15481-4.

15.

2'-O-aminopropyl ribonucleotides: a zwitterionic modification that enhances the exonuclease resistance and biological activity of antisense oligonucleotides.

Griffey RH, Monia BP, Cummins LL, Freier S, Greig MJ, Guinosso CJ, Lesnik E, Manalili SM, Mohan V, Owens S, Ross BR, Sasmor H, Wancewicz E, Weiler K, Wheeler PD, Cook PD.

J Med Chem. 1996 Dec 20;39(26):5100-9.

PMID:
8978841
16.

Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytes.

Hanecak R, Brown-Driver V, Fox MC, Azad RF, Furusako S, Nozaki C, Ford C, Sasmor H, Anderson KP.

J Virol. 1996 Aug;70(8):5203-12.

17.

Nuclease resistance and antisense activity of modified oligonucleotides targeted to Ha-ras.

Monia BP, Johnston JF, Sasmor H, Cummins LL.

J Biol Chem. 1996 Jun 14;271(24):14533-40.

18.

Pharmacokinetic properties of several novel oligonucleotide analogs in mice.

Crooke ST, Graham MJ, Zuckerman JE, Brooks D, Conklin BS, Cummins LL, Greig MJ, Guinosso CJ, Kornbrust D, Manoharan M, Sasmor HM, Schleich T, Tivel KL, Griffey RH.

J Pharmacol Exp Ther. 1996 May;277(2):923-37.

PMID:
8627575
19.

Disposition of the 14C-labeled phosphorothioate oligonucleotide ISIS 2105 after intravenous administration to rats.

Cossum PA, Sasmor H, Dellinger D, Truong L, Cummins L, Owens SR, Markham PM, Shea JP, Crooke S.

J Pharmacol Exp Ther. 1993 Dec;267(3):1181-90.

PMID:
8166890
20.

Oligodeoxynucleotides containing 2'-O-modified adenosine: synthesis and effects on stability of DNA:RNA duplexes.

Lesnik EA, Guinosso CJ, Kawasaki AM, Sasmor H, Zounes M, Cummins LL, Ecker DJ, Cook PD, Freier SM.

Biochemistry. 1993 Aug 3;32(30):7832-8.

PMID:
7688569
21.

Antisense oligodeoxynucleotides: synthesis, biophysical and biological evaluation of oligodeoxynucleotides containing modified pyrimidines.

Sanghvi YS, Hoke GD, Freier SM, Zounes MC, Gonzalez C, Cummins L, Sasmor H, Cook PD.

Nucleic Acids Res. 1993 Jul 11;21(14):3197-203.

22.

Synthesis and biological studies with dithioate DNA.

Caruthers MH, Beaton G, Cummins L, Graff D, Hall M, Marshall WS, Sasmor H, Wiesler W.

Nucleic Acids Symp Ser. 1991;(24):91-4. No abstract available.

PMID:
1726757
23.

Synthesis and biochemical studies of dithioate DNA.

Caruthers MH, Beaton G, Cummins L, Graff D, Ma YX, Marshall WS, Sasmor H, Norris P, Yau EK.

Ciba Found Symp. 1991;158:158-66; discussion 166-8. Review.

PMID:
1718668
24.

Specific binding of lac repressor to linear versus circular polyoperator molecules.

Sasmor HM, Betz JL.

Biochemistry. 1990 Sep 25;29(38):9023-8.

PMID:
2271575
25.
26.

Base substitution mutants of the lac operator: in vivo and in vitro affinities for lac repressor.

Betz JL, Sasmor HM, Buck F, Insley MY, Caruthers MH.

Gene. 1986;50(1-3):123-32.

PMID:
3556322
27.

A perfectly symmetric lac operator binds the lac repressor very tightly.

Sadler JR, Sasmor H, Betz JL.

Proc Natl Acad Sci U S A. 1983 Nov;80(22):6785-9.

28.

Positive and negative geotaxis: sex-linked traits in Drosophila pseudoobscura.

Woolf CM, Sasmor HM, Markow TA.

Behav Genet. 1978 Jan;8(1):65-71.

PMID:
565202

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