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Items: 1 to 50 of 101

1.

Processing of a single ribonucleotide embedded into DNA by human nucleotide excision repair and DNA polymerase η.

Sassa A, Tada H, Takeishi A, Harada K, Suzuki M, Tsuda M, Sasanuma H, Takeda S, Sugasawa K, Yasui M, Honma M, Ura K.

Sci Rep. 2019 Sep 26;9(1):13910. doi: 10.1038/s41598-019-50421-8.

2.

Dual usage of a stage-specific fluorescent reporter system based on a helper-dependent adenoviral vector to visualize osteogenic differentiation.

Sone T, Shin M, Ouchi T, Sasanuma H, Miyamoto A, Ohte S, Tsukamoto S, Nakanishi M, Okano H, Katagiri T, Mitani K.

Sci Rep. 2019 Jul 4;9(1):9705. doi: 10.1038/s41598-019-46105-y.

3.

Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations.

Gothe HJ, Bouwman BAM, Gusmao EG, Piccinno R, Petrosino G, Sayols S, Drechsel O, Minneker V, Josipovic N, Mizi A, Nielsen CF, Wagner EM, Takeda S, Sasanuma H, Hudson DF, Kindler T, Baranello L, Papantonis A, Crosetto N, Roukos V.

Mol Cell. 2019 Jul 25;75(2):267-283.e12. doi: 10.1016/j.molcel.2019.05.015. Epub 2019 Jun 12.

PMID:
31202576
4.

Srs2 helicase prevents the formation of toxic DNA damage during late prophase I of yeast meiosis.

Sasanuma H, Sakurai HSM, Furihata Y, Challa K, Palmer L, Gasser SM, Shinohara M, Shinohara A.

Chromosoma. 2019 Jun 6. doi: 10.1007/s00412-019-00709-5. [Epub ahead of print]

PMID:
31168653
5.

Down-regulation of GATA1-dependent erythrocyte-related genes in the spleens of mice exposed to a space travel.

Horie K, Sasanuma H, Kudo T, Fujita SI, Miyauchi M, Miyao T, Seki T, Akiyama N, Takakura Y, Shimbo M, Jeon H, Shirakawa M, Shiba D, Yoshida N, Muratani M, Takahashi S, Akiyama T.

Sci Rep. 2019 May 21;9(1):7654. doi: 10.1038/s41598-019-44067-9.

6.

The course and clinical impact of articular magnetic resonance imaging findings 6 months after shoulder manipulation under ultrasound-guided cervical nerve root block for frozen shoulder.

Saito T, Sugimoto H, Sasanuma H, Iijima Y, Kanaya Y, Fukushima T, Watanabe H, Kikkawa I, Takeshita K.

JSES Open Access. 2019 Mar 18;3(1):21-24. doi: 10.1016/j.jses.2018.11.001. eCollection 2019 Mar.

7.

PDIP38/PolDIP2 controls the DNA damage tolerance pathways by increasing the relative usage of translesion DNA synthesis over template switching.

Tsuda M, Ogawa S, Ooka M, Kobayashi K, Hirota K, Wakasugi M, Matsunaga T, Sakuma T, Yamamoto T, Chikuma S, Sasanuma H, Debatisse M, Doherty AJ, Fuchs RP, Takeda S.

PLoS One. 2019 Mar 6;14(3):e0213383. doi: 10.1371/journal.pone.0213383. eCollection 2019.

8.

BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.

Zong D, Adam S, Wang Y, Sasanuma H, Callén E, Murga M, Day A, Kruhlak MJ, Wong N, Munro M, Ray Chaudhuri A, Karim B, Xia B, Takeda S, Johnson N, Durocher D, Nussenzweig A.

Mol Cell. 2019 Mar 21;73(6):1267-1281.e7. doi: 10.1016/j.molcel.2018.12.010. Epub 2019 Jan 28.

PMID:
30704900
9.

Thymoma with an isolated splenic metastasis eight years after extended thymectomy: a case report.

Aoki Y, Miki A, Nakano T, Sasanuma H, Sakuma Y, Horie H, Hosoya Y, Fukushima N, Lefor AK, Sata N.

BMC Cancer. 2018 Dec 13;18(1):1249. doi: 10.1186/s12885-018-5165-0.

10.

SUMOylation of PCNA by PIAS1 and PIAS4 promotes template switch in the chicken and human B cell lines.

Mohiuddin M, Evans TJ, Rahman MM, Keka IS, Tsuda M, Sasanuma H, Takeda S.

Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):12793-12798. doi: 10.1073/pnas.1716349115. Epub 2018 Nov 28.

11.

RNA-binding protein Ptbp1 is essential for BCR-mediated antibody production.

Sasanuma H, Ozawa M, Yoshida N.

Int Immunol. 2019 Mar 5;31(3):157-166. doi: 10.1093/intimm/dxy077.

12.

BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes.

Sasanuma H, Tsuda M, Morimoto S, Saha LK, Rahman MM, Kiyooka Y, Fujiike H, Cherniack AD, Itou J, Callen Moreu E, Toi M, Nakada S, Tanaka H, Tsutsui K, Yamada S, Nussenzweig A, Takeda S.

Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10642-E10651. doi: 10.1073/pnas.1803177115. Epub 2018 Oct 23.

13.

Pain Deterioration Within 1 Year Predicts Future Decline of Walking Ability: A 7-Year Prospective Observational Study of Elderly Female Patients With Knee Osteoarthritis Living in a Rural District.

Yamaguchi N, Takahashi T, Ueno T, Hiyama S, Ogawa M, Matsumura T, Sasanuma H, Takeshita K.

Geriatr Orthop Surg Rehabil. 2018 Sep 19;9:2151459318799855. doi: 10.1177/2151459318799855. eCollection 2018.

14.

Blood flow evaluation by dynamic magnetic resonance imaging of symptomatic rotator cuff tears and frozen shoulders.

Sasanuma H, Sugimoto H, Iijima Y, Kanaya Y, Saito T, Takeshita K.

J Shoulder Elbow Surg. 2018 Dec;27(12):e372-e379. doi: 10.1016/j.jse.2018.05.042. Epub 2018 Aug 13.

PMID:
30111504
15.

Differential micronucleus frequency in isogenic human cells deficient in DNA repair pathways is a valuable indicator for evaluating genotoxic agents and their genotoxic mechanisms.

Saha LK, Kim S, Kang H, Akter S, Choi K, Sakuma T, Yamamoto T, Sasanuma H, Hirota K, Nakamura J, Honma M, Takeda S, Dertinger S.

Environ Mol Mutagen. 2018 Jul;59(6):529-538. doi: 10.1002/em.22201. Epub 2018 May 15.

PMID:
29761828
16.

Long-term hindlimb unloading causes a preferential reduction of medullary thymic epithelial cells expressing autoimmune regulator (Aire).

Horie K, Kudo T, Yoshinaga R, Akiyama N, Sasanuma H, Kobayashi TJ, Shimbo M, Jeon H, Miyao T, Miyauchi M, Shirakawa M, Shiba D, Yoshida N, Muratani M, Takahashi S, Akiyama T.

Biochem Biophys Res Commun. 2018 Jun 27;501(3):745-750. doi: 10.1016/j.bbrc.2018.05.060.

PMID:
29753741
17.

Disruption of Hif-1α enhances cytotoxic effects of metformin in murine squamous cell carcinoma.

Sanada Y, Sasanuma H, Takeda S, Tano K, Masunaga SI.

Int J Radiat Biol. 2018 Jan;94(1):88-96. doi: 10.1080/09553002.2018.1409443. Epub 2017 Dec 12.

PMID:
29185833
18.

Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts.

Çaglayan M, Prasad R, Krasich R, Longley MJ, Kadoda K, Tsuda M, Sasanuma H, Takeda S, Tano K, Copeland WC, Wilson SH.

Nucleic Acids Res. 2017 Sep 29;45(17):10079-10088. doi: 10.1093/nar/gkx654.

19.

Selective cytotoxicity of the anti-diabetic drug, metformin, in glucose-deprived chicken DT40 cells.

Kadoda K, Moriwaki T, Tsuda M, Sasanuma H, Ishiai M, Takata M, Ide H, Masunaga SI, Takeda S, Tano K.

PLoS One. 2017 Sep 19;12(9):e0185141. doi: 10.1371/journal.pone.0185141. eCollection 2017.

20.

TDP1 is Critical for the Repair of DNA Breaks Induced by Sapacitabine, a Nucleoside also Targeting ATM- and BRCA-Deficient Tumors.

Al Abo M, Sasanuma H, Liu X, Rajapakse VN, Huang SY, Kiselev E, Takeda S, Plunkett W, Pommier Y.

Mol Cancer Ther. 2017 Nov;16(11):2543-2551. doi: 10.1158/1535-7163.MCT-17-0110. Epub 2017 Aug 11.

21.

PDK1-FoxO1 pathway in AgRP neurons of arcuate nucleus promotes bone formation via GHRH-GH-IGF1 axis.

Sasanuma H, Nakata M, Parmila K, Nakae J, Yada T.

Mol Metab. 2017 Feb 17;6(5):428-439. doi: 10.1016/j.molmet.2017.02.003. eCollection 2017 May.

22.

The dominant role of proofreading exonuclease activity of replicative polymerase ε in cellular tolerance to cytarabine (Ara-C).

Tsuda M, Terada K, Ooka M, Kobayashi K, Sasanuma H, Fujisawa R, Tsurimoto T, Yamamoto J, Iwai S, Kadoda K, Akagawa R, Huang SN, Pommier Y, Sale JE, Takeda S, Hirota K.

Oncotarget. 2017 May 16;8(20):33457-33474. doi: 10.18632/oncotarget.16508.

23.

Recurrent Intrathoracic Locking of the Scapula after Lung Cancer Resection and Combined Rib Resection.

Kimura A, Sasanuma H, Ajiki T, Sekiya H, Takeshita K.

Case Rep Orthop. 2017;2017:8486739. doi: 10.1155/2017/8486739. Epub 2017 Mar 1.

24.

Pediatric living donor liver transplantation for congenital hepatic fibrosis using a mother's graft with von Meyenburg complex: A case report.

Yamada N, Sanada Y, Katano T, Tashiro M, Hirata Y, Okada N, Ihara Y, Miki A, Sasanuma H, Urahashi T, Sakuma Y, Mizuta K.

World J Gastroenterol. 2016 Nov 28;22(44):9865-9870.

25.

Cytotoxicity of Tirapazamine (3-Amino-1,2,4-benzotriazine-1,4-dioxide)-Induced DNA Damage in Chicken DT40 Cells.

Moriwaki T, Okamoto S, Sasanuma H, Nagasawa H, Takeda S, Masunaga SI, Tano K.

Chem Res Toxicol. 2017 Feb 20;30(2):699-704. doi: 10.1021/acs.chemrestox.6b00417. Epub 2016 Dec 27.

PMID:
27943678
26.

Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes.

Hoa NN, Shimizu T, Zhou ZW, Wang ZQ, Deshpande RA, Paull TT, Akter S, Tsuda M, Furuta R, Tsutsui K, Takeda S, Sasanuma H.

Mol Cell. 2016 Dec 1;64(5):1010. doi: 10.1016/j.molcel.2016.11.028. No abstract available.

27.

Short-term clinical results of frozen shoulder treated with shoulder manipulation under ultrasound-guided cervical nerve root block at outpatient setting: A case series.

Saito T, Sasanuma H, Iijima Y, Kanaya Y, Saito T, Watanabe H, Kikkawa I, Takeshita K.

J Orthop Sci. 2017 Mar;22(2):275-280. doi: 10.1016/j.jos.2016.11.007. Epub 2016 Nov 25.

PMID:
27890438
28.

Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes.

Hoa NN, Shimizu T, Zhou ZW, Wang ZQ, Deshpande RA, Paull TT, Akter S, Tsuda M, Furuta R, Tsutsui K, Takeda S, Sasanuma H.

Mol Cell. 2016 Nov 3;64(3):580-592. doi: 10.1016/j.molcel.2016.10.011. Erratum in: Mol Cell. 2016 Dec 1;64(5):1010.

29.

Immunohistochemical evaluation for outflow reconstruction using opened round ligament in living donor right posterior sector graft liver transplantation: A case report.

Sanada Y, Sakuma Y, Sasanuma H, Miki A, Katano T, Hirata Y, Okada N, Yamada N, Ihara Y, Urahashi T, Sata N, Yasuda Y, Mizuta K.

World J Gastroenterol. 2016 Sep 14;22(34):7851-6. doi: 10.3748/wjg.v22.i34.7851.

30.

Characteristics of dynamic magnetic resonance imaging of idiopathic severe frozen shoulder.

Sasanuma H, Sugimoto H, Fujita A, Kanaya Y, Iijima Y, Saito T, Takeshita K.

J Shoulder Elbow Surg. 2017 Feb;26(2):e52-e57. doi: 10.1016/j.jse.2016.06.003. Epub 2016 Aug 15.

PMID:
27539943
31.

Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells.

Hashimoto K, Sharma V, Sasanuma H, Tian X, Takata M, Takeda S, Swenberg JA, Nakamura J.

Oncotarget. 2016 Sep 13;7(37):59795-59808. doi: 10.18632/oncotarget.10928.

32.

The effect of ultrasound with acoustic radiation force on rabbit lung tissue: a preliminary study.

Takayama N, Ishiguro Y, Taniguchi N, Akai K, Sasanuma H, Yasuda Y, Nitta N, Akiyama I.

J Med Ultrason (2001). 2016 Oct;43(4):481-5. doi: 10.1007/s10396-016-0730-0. Epub 2016 Jul 11.

PMID:
27401323
33.

Complementary Indicators for Diagnosis of Hepatic Vein Stenosis After Pediatric Living-donor Liver Transplantation.

Kawano Y, Mizuta K, Sanada Y, Urahashi T, Ihara Y, Okada N, Yamada N, Sasanuma H, Sakuma Y, Taniai N, Yoshida H, Kawarasaki H, Yasuda Y, Uchida E.

Transplant Proc. 2016 May;48(4):1156-61. doi: 10.1016/j.transproceed.2015.12.114.

PMID:
27320577
34.

Living-Donor Liver Transplantation Using Segment 2 Monosegment Graft: A Single-Center Experience.

Sakuma Y, Sasanuma H, Miki A, Shimizu A, Sata N, Yasuda Y, Lefor AK, Hirata Y, Yamada N, Okada N, Sanada Y, Ihara Y, Urahashi T, Mizuta K.

Transplant Proc. 2016 May;48(4):1110-4. doi: 10.1016/j.transproceed.2015.12.119.

PMID:
27320568
35.

The role of the Mre11-Rad50-Nbs1 complex in double-strand break repair-facts and myths.

Takeda S, Hoa NN, Sasanuma H.

J Radiat Res. 2016 Aug;57 Suppl 1:i25-i32. doi: 10.1093/jrr/rrw034. Epub 2016 Jun 15.

36.

Deazaflavin Inhibitors of Tyrosyl-DNA Phosphodiesterase 2 (TDP2) Specific for the Human Enzyme and Active against Cellular TDP2.

Marchand C, Abdelmalak M, Kankanala J, Huang SY, Kiselev E, Fesen K, Kurahashi K, Sasanuma H, Takeda S, Aihara H, Wang Z, Pommier Y.

ACS Chem Biol. 2016 Jul 15;11(7):1925-33. doi: 10.1021/acschembio.5b01047. Epub 2016 May 11.

PMID:
27128689
37.

The role of HERC2 and RNF8 ubiquitin E3 ligases in the promotion of translesion DNA synthesis in the chicken DT40 cell line.

Mohiuddin, Kobayashi S, Keka IS, Guilbaud G, Sale J, Narita T, Abdel-Aziz HI, Wang X, Ogawa S, Sasanuma H, Chiu R, Oestergaard VH, Lisby M, Takeda S.

DNA Repair (Amst). 2016 Apr;40:67-76. doi: 10.1016/j.dnarep.2016.02.002. Epub 2016 Mar 2.

38.

Ground-based assessment of JAXA mouse habitat cage unit by mouse phenotypic studies.

Shimbo M, Kudo T, Hamada M, Jeon H, Imamura Y, Asano K, Okada R, Tsunakawa Y, Mizuno S, Yagami K, Ishikawa C, Li H, Shiga T, Ishida J, Hamada J, Murata K, Ishimaru T, Hashimoto M, Fukamizu A, Yamane M, Ikawa M, Morita H, Shinohara M, Asahara H, Akiyama T, Akiyama N, Sasanuma H, Yoshida N, Zhou R, Wang YY, Ito T, Kokubu Y, Noguchi TA, Ishimine H, Kurisaki A, Shiba D, Mizuno H, Shirakawa M, Ito N, Takeda S, Takahashi S.

Exp Anim. 2016 May 20;65(2):175-87. doi: 10.1538/expanim.15-0077. Epub 2016 Jan 28.

39.

The outcomes of pediatric living donor liver transplantation using small-for-size grafts: experience of a single institute.

Yamada N, Sanada Y, Hirata Y, Okada N, Ihara Y, Sasanuma H, Urahashi T, Sakuma Y, Yasuda Y, Mizuta K.

Pediatr Surg Int. 2016 Apr;32(4):363-8. doi: 10.1007/s00383-016-3859-4. Epub 2016 Jan 19.

PMID:
26786017
40.

Erratum to: Ultrasound exposure (mechanical index 1.8) with acoustic radiation force impulse evokes extrasystolic waves in rabbit heart under concomitant administration of an ultrasound contrast agent.

Ishiguro Y, Nitta N, Taniguchi N, Akai K, Takayama N, Sasanuma H, Ogata Y, Yasuda Y, Akiyama I.

J Med Ultrason (2001). 2016 Jan;43(1):9. doi: 10.1007/s10396-015-0683-8. No abstract available.

PMID:
26703161
41.

Ultrasound exposure (mechanical index 1.8) with acoustic radiation force impulse evokes extrasystolic waves in rabbit heart under concomitant administration of an ultrasound contrast agent.

Ishiguro Y, Nitta N, Taniguchi N, Akai K, Takakayama N, Sasanuma H, Ogata Y, Yasuda Y, Akiyama I.

J Med Ultrason (2001). 2016 Jan;43(1):3-7. doi: 10.1007/s10396-015-0654-0. Epub 2015 Sep 3. Erratum in: J Med Ultrason (2001). 2016 Jan;43(1):9.

PMID:
26703160
42.

The Double-Strand Break Landscape of Meiotic Chromosomes Is Shaped by the Paf1 Transcription Elongation Complex in Saccharomyces cerevisiae.

Gothwal SK, Patel NJ, Colletti MM, Sasanuma H, Shinohara M, Hochwagen A, Shinohara A.

Genetics. 2016 Feb;202(2):497-512. doi: 10.1534/genetics.115.177287. Epub 2015 Dec 1.

43.

Abacavir, an anti-HIV-1 drug, targets TDP1-deficient adult T cell leukemia.

Tada K, Kobayashi M, Takiuchi Y, Iwai F, Sakamoto T, Nagata K, Shinohara M, Io K, Shirakawa K, Hishizawa M, Shindo K, Kadowaki N, Hirota K, Yamamoto J, Iwai S, Sasanuma H, Takeda S, Takaori-Kondo A.

Sci Adv. 2015 Apr 24;1(3):e1400203. doi: 10.1126/sciadv.1400203. eCollection 2015 Apr.

44.

The arrhythmogenic effect of ultrasonic exposure with acoustic radiation force (ARF) impulse on the rabbit heart with ultrasound contrast agent perfluorobutane.

Ishiguro Y, Sasanuma H, Nitta N, Taniguchi N, Ogata Y, Yasuda Y, Akiyama I.

J Med Ultrason (2001). 2015 Jan;42(1):47-50. doi: 10.1007/s10396-014-0573-5. Epub 2014 Sep 19.

PMID:
26578489
45.

Experimental system for in-situ measurement of temperature rise in animal tissue under exposure to acoustic radiation force impulse.

Nitta N, Ishiguro Y, Sasanuma H, Taniguchi N, Akiyama I.

J Med Ultrason (2001). 2015 Jan;42(1):39-46. doi: 10.1007/s10396-014-0562-8. Epub 2014 Aug 13.

PMID:
26578488
46.

Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell lines.

Hoa NN, Akagawa R, Yamasaki T, Hirota K, Sasa K, Natsume T, Kobayashi J, Sakuma T, Yamamoto T, Komatsu K, Kanemaki MT, Pommier Y, Takeda S, Sasanuma H.

Genes Cells. 2015 Dec;20(12):1059-76. doi: 10.1111/gtc.12310. Epub 2015 Nov 2.

47.

Hypergravity Provokes a Temporary Reduction in CD4+CD8+ Thymocyte Number and a Persistent Decrease in Medullary Thymic Epithelial Cell Frequency in Mice.

Tateishi R, Akiyama N, Miyauchi M, Yoshinaga R, Sasanuma H, Kudo T, Shimbo M, Shinohara M, Obata K, Inoue J, Shirakawa M, Shiba D, Asahara H, Yoshida N, Takahashi S, Morita H, Akiyama T.

PLoS One. 2015 Oct 29;10(10):e0141650. doi: 10.1371/journal.pone.0141650. eCollection 2015.

48.

Magnetic resonance imaging and short-term clinical results of severe frozen shoulder treated with manipulation under ultrasound-guided cervical nerve root block.

Sasanuma H, Sugimoto H, Kanaya Y, Iijima Y, Saito T, Saito T, Takeshita K.

J Shoulder Elbow Surg. 2016 Jan;25(1):e13-20. doi: 10.1016/j.jse.2015.06.019. Epub 2015 Aug 6.

PMID:
26256012
49.

Smarcal1 promotes double-strand-break repair by nonhomologous end-joining.

Keka IS, Mohiuddin, Maede Y, Rahman MM, Sakuma T, Honma M, Yamamoto T, Takeda S, Sasanuma H.

Nucleic Acids Res. 2015 Jul 27;43(13):6359-72. doi: 10.1093/nar/gkv621. Epub 2015 Jun 18.

50.

BRCA1 and CtIP Are Both Required to Recruit Dna2 at Double-Strand Breaks in Homologous Recombination.

Hoa NN, Kobayashi J, Omura M, Hirakawa M, Yang SH, Komatsu K, Paull TT, Takeda S, Sasanuma H.

PLoS One. 2015 Apr 24;10(4):e0124495. doi: 10.1371/journal.pone.0124495. eCollection 2015.

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