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Items: 1 to 50 of 537

1.

WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4.

Mandai S, Mori T, Nomura N, Furusho T, Arai Y, Kikuchi H, Sasaki E, Sohara E, Rai T, Uchida S.

Sci Rep. 2018 Jun 14;8(1):9101. doi: 10.1038/s41598-018-27414-0.

2.

Development of a preclinical humanized mouse model to evaluate acute toxicity of an influenza vaccine.

Sasaki E, Momose H, Hiradate Y, Furuhata K, Mizukami T, Hamaguchi I.

Oncotarget. 2018 May 25;9(40):25751-25763. doi: 10.18632/oncotarget.25399. eCollection 2018 May 25.

3.

TAS-303, a novel selective norepinephrine reuptake inhibitor that increases urethral pressure in rats, indicating its potential as a therapeutic agent for stress urinary incontinence.

Mizutani H, Sakakibara F, Komuro M, Sasaki E.

J Pharmacol Exp Ther. 2018 Jun 6. pii: jpet.118.248039. doi: 10.1124/jpet.118.248039. [Epub ahead of print]

4.

HNRNPLL stabilizes mRNAs for DNA replication proteins and promotes cell cycle progression in colorectal cancer cells.

Sakuma K, Sasaki E, Kimura K, Komori K, Shimizu Y, Yatabe Y, Aoki M.

Cancer Sci. 2018 Jun 5. doi: 10.1111/cas.13660. [Epub ahead of print]

5.

Decreased KLHL3 expression is involved in the pathogenesis of pseudohypoaldosteronism type II caused by cullin 3 mutation in vivo.

Yoshida S, Araki Y, Mori T, Sasaki E, Kasagi Y, Isobe K, Susa K, Inoue Y, Bomont P, Okado T, Rai T, Uchida S, Sohara E.

Clin Exp Nephrol. 2018 Jun 5. doi: 10.1007/s10157-018-1593-z. [Epub ahead of print]

PMID:
29869755
6.

The Marmoset as an Animal Model of Influenza: Infection With A(H1N1)pdm09 and Highly Pathogenic A(H5N1) Viruses via the Conventional or Tracheal Spray Route.

Iwatsuki-Horimoto K, Nakajima N, Kiso M, Takahashi K, Ito M, Inoue T, Horiuchi M, Okahara N, Sasaki E, Hasegawa H, Kawaoka Y.

Front Microbiol. 2018 May 9;9:844. doi: 10.3389/fmicb.2018.00844. eCollection 2018.

7.

Two-photon imaging of neuronal activity in motor cortex of marmosets during upper-limb movement tasks.

Ebina T, Masamizu Y, Tanaka YR, Watakabe A, Hirakawa R, Hirayama Y, Hira R, Terada SI, Koketsu D, Hikosaka K, Mizukami H, Nambu A, Sasaki E, Yamamori T, Matsuzaki M.

Nat Commun. 2018 May 14;9(1):1879. doi: 10.1038/s41467-018-04286-6.

8.

TAS05567, a Novel Potent and Selective Spleen Tyrosine Kinase Inhibitor, Abrogates Immunoglobulin-Mediated Autoimmune and Allergic Reactions in Rodent Models.

Hayashi H, Kaneko R, Demizu S, Akasaka D, Tayama M, Harada T, Irie H, Ogino Y, Fujino N, Sasaki E.

J Pharmacol Exp Ther. 2018 Jul;366(1):84-95. doi: 10.1124/jpet.118.248153. Epub 2018 May 4.

9.

Therapeutic effect of TAC-302, a cyclohexenoic fatty alcohol derivative, on bladder denervation-related storage and voiding dysfunctions in rats.

Yoshida S, Noma T, Miyoshi K, Tsukihara H, Orimoto N, Hakozaki A, Sasaki E.

Neurourol Urodyn. 2018 Apr 10. doi: 10.1002/nau.23571. [Epub ahead of print]

PMID:
29635706
10.

In vivo and in vitro diclofenac 5-hydroxylation mediated primarily by cytochrome P450 3A enzymes in common marmoset livers genotyped for P450 2C19 variants.

Nakanishi K, Uehara S, Kusama T, Inoue T, Shimura K, Kamiya Y, Murayama N, Shimizu M, Uno Y, Sasaki E, Yamazaki H.

Biochem Pharmacol. 2018 Jun;152:272-278. doi: 10.1016/j.bcp.2018.04.002. Epub 2018 Apr 5.

PMID:
29626440
11.

Levels of Anti-Retinal Antibodies in Retinal Detachment and Proliferative Vitreoretinopathy.

Ichinohasama R, Nishiguchi KM, Fujita K, Aizawa N, Inoue T, Sasaki E, Kunikata H, Nakazawa T.

Curr Eye Res. 2018 Jun;43(6):804-809. doi: 10.1080/02713683.2018.1451544. Epub 2018 Mar 16.

PMID:
29547015
12.

Identification of Cha o 3 homolog Cry j 4 from Cryptomeria japonica (Japanese cedar) pollen: Limitation of the present Japanese cedar-specific ASIT.

Osada T, Tanaka Y, Yamada A, Sasaki E, Utsugi T.

Allergol Int. 2018 Mar 7. pii: S1323-8930(18)30009-1. doi: 10.1016/j.alit.2018.02.004. [Epub ahead of print]

13.

In vitro marker gene expression analyses in human peripheral blood mononuclear cells: A tool to assess safety of influenza vaccines in humans.

Sasaki E, Momose H, Hiradate Y, Ishii KJ, Mizukami T, Hamaguchi I.

J Immunotoxicol. 2018 Dec;15(1):53-62. doi: 10.1080/1547691X.2018.1447052.

PMID:
29521144
14.

A Case of Squamous Cell Carcinoma of Unknown Primary that Responded to the Multi-Tyrosine Kinase Inhibitor Lenvatinib.

Kimura-Tsuchiya R, Sasaki E, Nakamura I, Suzuki S, Kawana S, Okouchi C, Fukushima T, Hashimoto Y, Suzuki S, Saji S.

Case Rep Oncol. 2018 Feb 9;11(1):75-80. doi: 10.1159/000486569. eCollection 2018 Jan-Apr.

15.
16.

Age-related reduction of trunk muscle torque and prevalence of trunk sarcopenia in community-dwelling elderly: Validity of a portable trunk muscle torque measurement instrument and its application to a large sample cohort study.

Sasaki E, Sasaki S, Chiba D, Yamamoto Y, Nawata A, Tsuda E, Nakaji S, Ishibashi Y.

PLoS One. 2018 Feb 22;13(2):e0192687. doi: 10.1371/journal.pone.0192687. eCollection 2018.

17.

Thioacetamide-induced hepatic fibrosis in the common marmoset.

Inoue T, Ishizaka Y, Sasaki E, Lu J, Mineshige T, Yanase M, Sasaki E, Shimoda M.

Exp Anim. 2018 Feb 21. doi: 10.1538/expanim.17-0156. [Epub ahead of print]

18.

Oocyte-activating capacity of fresh and frozen-thawed spermatids in the common marmoset (Callithrix jacchus).

Ogonuki N, Inoue H, Matoba S, Kurotaki YK, Kassai H, Abe Y, Sasaki E, Aiba A, Ogura A.

Mol Reprod Dev. 2018 May;85(5):376-386. doi: 10.1002/mrd.22971. Epub 2018 Mar 23.

PMID:
29457675
19.

Marmoset cytochrome P450 2B6, a propofol hydroxylase expressed in liver.

Oshio T, Uehara S, Uno Y, Inoue T, Sasaki E, Yamazaki H.

Xenobiotica. 2018 Feb 21:1-5. doi: 10.1080/00498254.2018.1439204. [Epub ahead of print]

PMID:
29417863
20.

Comparative immunity of antigen recognition, differentiation, and other functional molecules: similarities and differences among common marmosets, humans, and mice.

Kametani Y, Shiina T, Suzuki R, Sasaki E, Habu S.

Exp Anim. 2018 Feb 8. doi: 10.1538/expanim.17-0150. [Epub ahead of print]

21.

Modeling for influenza vaccines and adjuvants profile for safety prediction system using gene expression profiling and statistical tools.

Sasaki E, Momose H, Hiradate Y, Furuhata K, Takai M, Asanuma H, Ishii KJ, Mizukami T, Hamaguchi I.

PLoS One. 2018 Feb 6;13(2):e0191896. doi: 10.1371/journal.pone.0191896. eCollection 2018.

22.

The response of common marmoset immunity against cedar pollen extract.

Kametani Y, Yamada Y, Takabayashi S, Kato H, Ishiwata K, Watanabe N, Sasaki E, Habu S.

Biosci Trends. 2018 Mar 18;12(1):94-101. doi: 10.5582/bst.2017.01219. Epub 2018 Jan 15.

23.

Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics.

Cowell AN, Istvan ES, Lukens AK, Gomez-Lorenzo MG, Vanaerschot M, Sakata-Kato T, Flannery EL, Magistrado P, Owen E, Abraham M, LaMonte G, Painter HJ, Williams RM, Franco V, Linares M, Arriaga I, Bopp S, Corey VC, Gnädig NF, Coburn-Flynn O, Reimer C, Gupta P, Murithi JM, Moura PA, Fuchs O, Sasaki E, Kim SW, Teng CH, Wang LT, Akidil A, Adjalley S, Willis PA, Siegel D, Tanaseichuk O, Zhong Y, Zhou Y, Llinás M, Ottilie S, Gamo FJ, Lee MCS, Goldberg DE, Fidock DA, Wirth DF, Winzeler EA.

Science. 2018 Jan 12;359(6372):191-199. doi: 10.1126/science.aan4472.

24.

Do you know otitis media with ANCA-Associated Vasculitis (OMAAV)?

Hisata Y, Sasaki E, Ishimaru K, Harada Y, Nakano H, Naitou S, Sugioka T.

J Gen Fam Med. 2017 Jun 21;18(6):428-431. doi: 10.1002/jgf2.112. eCollection 2017 Dec.

25.

Genetic engineering in nonhuman primates for human disease modeling.

Sato K, Sasaki E.

J Hum Genet. 2018 Feb;63(2):125-131. doi: 10.1038/s10038-017-0351-5. Epub 2017 Dec 4. Review.

PMID:
29203824
26.

Expanding the structural analysis capabilities on an Orbitrap-based mass spectrometer for large macromolecular complexes.

Fort KL, van de Waterbeemd M, Boll D, Reinhardt-Szyba M, Belov ME, Sasaki E, Zschoche R, Hilvert D, Makarov AA, Heck AJR.

Analyst. 2017 Dec 18;143(1):100-105. doi: 10.1039/c7an01629h.

PMID:
29138777
27.

PMO Delivery System Using Bubble Liposomes and Ultrasound Exposure for Duchenne Muscular Dystrophy Treatment.

Negishi Y, Ishii Y, Nirasawa K, Sasaki E, Endo-Takahashi Y, Suzuki R, Maruyama K.

Methods Mol Biol. 2018;1687:185-192. doi: 10.1007/978-1-4939-7374-3_13.

PMID:
29067664
28.

Molecular cloning and tissue distribution of a novel marmoset ABC transporter.

Uehara S, Uno Y, Inoue T, Sasaki E, Yamazaki H.

Biopharm Drug Dispos. 2018 Jan;39(1):59-63. doi: 10.1002/bdd.2111. Epub 2017 Dec 11.

PMID:
29059459
29.

Association with polymorphic marmoset cytochrome P450 2C19 of in vivo hepatic clearances of chirally separated R-omeprazole and S-warfarin using individual marmoset physiologically based pharmacokinetic models.

Kusama T, Toda A, Shimizu M, Uehara S, Inoue T, Uno Y, Utoh M, Sasaki E, Yamazaki H.

Xenobiotica. 2017 Nov 10:1-6. doi: 10.1080/00498254.2017.1393121. [Epub ahead of print]

PMID:
29034770
30.

Investigation of the Efficacy of an Administration Plan for Tazobactam/Piperacillin (TAZ/PIPC) and the Incidence of Kidney and Hepatic Disorders.

Senba M, Isami K, Yamashita K, Tsumagari K, Yamashina T, Sasaki E, Tsuruta M, Miyoshi T, Kawamata Y, Kozono A.

Yakugaku Zasshi. 2017;137(10):1277-1284. doi: 10.1248/yakushi.17-00016. Japanese.

31.

Developmental trajectories of macroanatomical structures in common marmoset brain.

Seki F, Hikishima K, Komaki Y, Hata J, Uematsu A, Okahara N, Yamamoto M, Shinohara H, Sasaki E, Okano H.

Neuroscience. 2017 Nov 19;364:143-156. doi: 10.1016/j.neuroscience.2017.09.021. Epub 2017 Sep 20.

PMID:
28939259
32.

Mapping orbitofrontal-limbic maturation in non-human primates: A longitudinal magnetic resonance imaging study.

Uematsu A, Hata J, Komaki Y, Seki F, Yamada C, Okahara N, Kurotaki Y, Sasaki E, Okano H.

Neuroimage. 2017 Dec;163:55-67. doi: 10.1016/j.neuroimage.2017.09.028. Epub 2017 Sep 18.

PMID:
28923274
33.

Meniscal extrusion seen on ultrasonography affects the development of radiographic knee osteoarthritis: a 3-year prospective cohort study.

Chiba D, Maeda S, Sasaki E, Ota S, Nakaji S, Tsuda E, Ishibashi Y.

Clin Rheumatol. 2017 Nov;36(11):2557-2564. doi: 10.1007/s10067-017-3803-6. Epub 2017 Sep 17.

PMID:
28920170
34.

Recurrent patellar dislocation with spontaneous valgus knee deformity treated by distal femoral osteotomy alone: A report of two cases.

Suzuki A, Kimura Y, Sasaki E, Narita A, Takagi M, Ishibashi Y.

J Orthop Sci. 2017 Sep 1. pii: S0949-2658(17)30216-6. doi: 10.1016/j.jos.2017.08.009. [Epub ahead of print] No abstract available.

PMID:
28870759
35.

Evaluation of marker gene expression as a potential predictive marker of leukopenic toxicity for inactivated influenza vaccines.

Sasaki E, Momose H, Hiradate Y, Furuhata K, Takai M, Kamachi K, Asanuma H, Ishii KJ, Mizukami T, Hamaguchi I.

Biologicals. 2017 Nov;50:100-108. doi: 10.1016/j.biologicals.2017.08.003. Epub 2017 Aug 31.

PMID:
28838806
36.

Progesterone hydroxylation by cytochromes P450 2C and 3A enzymes in marmoset liver microsomes.

Nakanishi K, Uehara S, Uno Y, Inoue T, Sasaki E, Yamazaki H.

Xenobiotica. 2018 Aug;48(8):757-763. doi: 10.1080/00498254.2017.1363444. Epub 2017 Aug 17.

PMID:
28762864
37.

TAC-302 promotes neurite outgrowth of isolated peripheral neurons and prevents bladder denervation related bladder dysfunctions following bladder outlet obstruction in rats.

Yoshida S, Orimoto N, Tsukihara H, Noma T, Hakozaki A, Sasaki E.

Neurourol Urodyn. 2018 Feb;37(2):681-689. doi: 10.1002/nau.23375. Epub 2017 Jul 26.

PMID:
28745805
38.

Development of Potent Myostatin Inhibitory Peptides through Hydrophobic Residue-Directed Structural Modification.

Takayama K, Rentier C, Asari T, Nakamura A, Saga Y, Shimada T, Nirasawa K, Sasaki E, Muguruma K, Taguchi A, Taniguchi A, Negishi Y, Hayashi Y.

ACS Med Chem Lett. 2017 Jun 6;8(7):751-756. doi: 10.1021/acsmedchemlett.7b00168. eCollection 2017 Jul 13.

PMID:
28740611
39.

Marmoset pulmonary cytochrome P450 2F1 oxidizes biphenyl and 7-ethoxycoumarin and hepatic human P450 substrates.

Uehara S, Uno Y, Oshio T, Inoue T, Sasaki E, Yamazaki H.

Xenobiotica. 2018 Jul;48(7):656-662. doi: 10.1080/00498254.2017.1354138. Epub 2017 Jul 24.

PMID:
28689458
40.

Effects of aging and rifampicin pretreatment on the pharmacokinetics of human cytochrome P450 probes caffeine, warfarin, omeprazole, metoprolol and midazolam in common marmosets genotyped for cytochrome P450 2C19.

Toda A, Uehara S, Inoue T, Utoh M, Kusama T, Shimizu M, Uno Y, Mogi M, Sasaki E, Yamazaki H.

Xenobiotica. 2018 Jul;48(7):720-726. doi: 10.1080/00498254.2017.1353716. Epub 2017 Jul 25.

PMID:
28686070
41.

Drug-Repositioning Screening for Keap1-Nrf2 Binding Inhibitors using Fluorescence Correlation Spectroscopy.

Yoshizaki Y, Mori T, Ishigami-Yuasa M, Kikuchi E, Takahashi D, Zeniya M, Nomura N, Mori Y, Araki Y, Ando F, Mandai S, Kasagi Y, Arai Y, Sasaki E, Yoshida S, Kagechika H, Rai T, Uchida S, Sohara E.

Sci Rep. 2017 Jun 21;7(1):3945. doi: 10.1038/s41598-017-04233-3.

42.

Glycoform of a newly identified pollen allergen, Cha o 3, from Chamaecyparis obtusa (Japanese cypress, Hinoki).

Osada T, Maeda M, Tanabe C, Furuta K, Vavricka CJ, Sasaki E, Okano M, Kimura Y.

Carbohydr Res. 2017 Aug 7;448:18-23. doi: 10.1016/j.carres.2017.05.005. Epub 2017 May 24.

PMID:
28575723
43.

An adult case of severe steroid-resistant Henoch-Schönlein purpura nephritis treated with intravenous cyclophosphamide and tonsillectomy.

Sasaki E, Shibata M, Kato A, Hamano N, Katsuki T, Tada M, Hinoshita F.

CEN Case Rep. 2016 Nov;5(2):212-218. doi: 10.1007/s13730-016-0227-0. Epub 2016 Jul 13.

44.

Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers.

Uehara S, Ishii S, Uno Y, Inoue T, Sasaki E, Yamazaki H.

Drug Metab Dispos. 2017 Aug;45(8):896-899. doi: 10.1124/dmd.117.075630. Epub 2017 May 11.

PMID:
28495902
45.

Molecular Cloning and Characterization of Marmoset Aldehyde Oxidase.

Uehara S, Uno Y, Okamoto E, Inoue T, Sasaki E, Yamazaki H.

Drug Metab Dispos. 2017 Aug;45(8):883-886. doi: 10.1124/dmd.117.076042. Epub 2017 May 9.

PMID:
28487309
46.

Functional characterization and tissue expression of marmoset cytochrome P450 2E1.

Uehara S, Uno Y, Tomioka E, Inoue T, Sasaki E, Yamazaki H.

Biopharm Drug Dispos. 2017 Sep;38(6):394-397. doi: 10.1002/bdd.2080. Epub 2017 Jun 28.

PMID:
28474789
47.

Uptake of 123I-metaiodobenzylguanidine by gastrointestinal stromal tumor.

Bhanthumkomol P, Hijioka S, Mizuno N, Kuwahara T, Okuno N, Ito A, Tanaka T, Ishihara M, Hirayama Y, Onishi S, Niwa Y, Tajika M, Ito Y, Sasaki E, Inaba Y, Shimizu Y, Yatabe Y, Hara K.

Clin J Gastroenterol. 2017 Aug;10(4):364-370. doi: 10.1007/s12328-017-0743-2. Epub 2017 Apr 26.

PMID:
28447327
48.

Terfenadine t-butyl hydroxylation catalyzed by human and marmoset cytochrome P450 3A and 4F enzymes in livers and small intestines.

Uehara S, Yuki Y, Uno Y, Inoue T, Sasaki E, Yamazaki H.

Xenobiotica. 2018 Apr;48(4):342-347. doi: 10.1080/00498254.2017.1321811. Epub 2017 May 15.

PMID:
28436281
49.

Loop diuretics affect skeletal myoblast differentiation and exercise-induced muscle hypertrophy.

Mandai S, Furukawa S, Kodaka M, Hata Y, Mori T, Nomura N, Ando F, Mori Y, Takahashi D, Yoshizaki Y, Kasagi Y, Arai Y, Sasaki E, Yoshida S, Furuichi Y, Fujii NL, Sohara E, Rai T, Uchida S.

Sci Rep. 2017 Apr 18;7:46369. doi: 10.1038/srep46369.

50.

Impaired degradation of medullary WNK4 in the kidneys of KLHL2 knockout mice.

Kasagi Y, Takahashi D, Aida T, Nishida H, Nomura N, Zeniya M, Mori T, Sasaki E, Ando F, Rai T, Uchida S, Sohara E.

Biochem Biophys Res Commun. 2017 May 27;487(2):368-374. doi: 10.1016/j.bbrc.2017.04.068. Epub 2017 Apr 14.

PMID:
28414128

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