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Items: 1 to 50 of 347

1.

An Eye Organoid Approach Identifies Six3 Suppression of R-spondin 2 as a Critical Step in Mouse Neuroretina Differentiation.

Takata N, Abbey D, Fiore L, Acosta S, Feng R, Gil HJ, Lavado A, Geng X, Interiano A, Neale G, Eiraku M, Sasai Y, Oliver G.

Cell Rep. 2017 Nov 7;21(6):1534-1549. doi: 10.1016/j.celrep.2017.10.041.

2.

Self-patterning of rostral-caudal neuroectoderm requires dual role of Fgf signaling for localized Wnt antagonism.

Takata N, Sakakura E, Eiraku M, Kasukawa T, Sasai Y.

Nat Commun. 2017 Nov 7;8(1):1339. doi: 10.1038/s41467-017-01105-2.

3.

Kinetic analysis of mechanoradical formation during the mechanolysis of dextran and glycogen.

Doi N, Sasai Y, Yamauchi Y, Adachi T, Kuzuya M, Kondo SI.

Beilstein J Org Chem. 2017 Jun 19;13:1174-1183. doi: 10.3762/bjoc.13.116. eCollection 2017.

4.

A RHO Small GTPase Regulator ABR Secures Mitotic Fidelity in Human Embryonic Stem Cells.

Ohgushi M, Minaguchi M, Eiraku M, Sasai Y.

Stem Cell Reports. 2017 Jul 11;9(1):58-66. doi: 10.1016/j.stemcr.2017.05.003. Epub 2017 Jun 1.

5.

Generation of thalamic neurons from mouse embryonic stem cells.

Shiraishi A, Muguruma K, Sasai Y.

Development. 2017 Apr 1;144(7):1211-1220. doi: 10.1242/dev.144071. Epub 2017 Feb 20.

6.

Vulnerability of Purkinje Cells Generated from Spinocerebellar Ataxia Type 6 Patient-Derived iPSCs.

Ishida Y, Kawakami H, Kitajima H, Nishiyama A, Sasai Y, Inoue H, Muguruma K.

Cell Rep. 2017 Jan 24;18(4):1075-1076. doi: 10.1016/j.celrep.2017.01.012. No abstract available.

7.

Plastic deformation of directionally solidified ingots of binary and some ternary MoSi2/Mo5Si3 eutectic composites.

Matsunoshita H, Sasai Y, Fujiwara K, Kishida K, Inui H.

Sci Technol Adv Mater. 2016 Sep 8;17(1):517-529. eCollection 2016.

8.

Vulnerability of Purkinje Cells Generated from Spinocerebellar Ataxia Type 6 Patient-Derived iPSCs.

Ishida Y, Kawakami H, Kitajima H, Nishiyama A, Sasai Y, Inoue H, Muguruma K.

Cell Rep. 2016 Nov 1;17(6):1482-1490. doi: 10.1016/j.celrep.2016.10.026. Erratum in: Cell Rep. 2017 Jan 24;18(4):1075-1076.

9.

Emergence of dorsal-ventral polarity in ESC-derived retinal tissue.

Hasegawa Y, Takata N, Okuda S, Kawada M, Eiraku M, Sasai Y.

Development. 2016 Nov 1;143(21):3895-3906. Epub 2016 Sep 15.

10.

Pancreaticoduodenal artery aneurysm associated with coeliac artery occlusion from an aortic intramural hematoma.

Sakatani A, Doi Y, Kitayama T, Matsuda T, Sasai Y, Nishida N, Sakamoto M, Uenoyama N, Kinoshita K.

World J Gastroenterol. 2016 Apr 28;22(16):4259-63. doi: 10.3748/wjg.v22.i16.4259.

11.

IGF-2/IGF-1R signaling has distinct effects on Sox1, Irx3, and Six3 expressions during ES cell derived-neuroectoderm development in vitro.

Takata N, Sakakura E, Sasai Y.

In Vitro Cell Dev Biol Anim. 2016 May;52(5):607-15. doi: 10.1007/s11626-016-0012-6. Epub 2016 Mar 8.

PMID:
26956358
12.

Establishment of Functional Genomics Pipeline in Mouse Epiblast-Like Tissue by Combining Transcriptomic Analysis and Gene Knockdown/Knockin/Knockout, Using RNA Interference and CRISPR/Cas9.

Takata N, Sakakura E, Kasukawa T, Sakuma T, Yamamoto T, Sasai Y.

Hum Gene Ther. 2016 Jun;27(6):436-50. doi: 10.1089/hum.2015.148. Epub 2016 Apr 28. Erratum in: Hum Gene Ther. 2016 Jul;27(7):560.

PMID:
26839115
13.

How potentially predictable are midlatitude ocean currents?

Nonaka M, Sasai Y, Sasaki H, Taguchi B, Nakamura H.

Sci Rep. 2016 Feb 1;6:20153. doi: 10.1038/srep20153.

14.

Functional anterior pituitary generated in self-organizing culture of human embryonic stem cells.

Ozone C, Suga H, Eiraku M, Kadoshima T, Yonemura S, Takata N, Oiso Y, Tsuji T, Sasai Y.

Nat Commun. 2016 Jan 14;7:10351. doi: 10.1038/ncomms10351.

15.

Transplantation of human embryonic stem cell-derived retinal tissue in two primate models of retinal degeneration.

Shirai H, Mandai M, Matsushita K, Kuwahara A, Yonemura S, Nakano T, Assawachananont J, Kimura T, Saito K, Terasaki H, Eiraku M, Sasai Y, Takahashi M.

Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E81-90. doi: 10.1073/pnas.1512590113. Epub 2015 Dec 22.

16.

The 2014 measles outbreak in Osaka An epidemiological study for the elimination of measles.

Yagi Y, Higashino H, Yoshida H, Hirokawa H, Okumachi A, Takano M, Nobuta M, Matuoka T, Sasai Y, Fukushima W, Tanaka T.

Nihon Koshu Eisei Zasshi. 2015;62(9):566-73. doi: 10.11236/jph.62.9_566. Japanese.

17.

Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue.

Sakaguchi H, Kadoshima T, Soen M, Narii N, Ishida Y, Ohgushi M, Takahashi J, Eiraku M, Sasai Y.

Nat Commun. 2015 Nov 17;6:8896. doi: 10.1038/ncomms9896.

18.

Activation of Wnt/ß-catenin signaling in ESC promotes rostral forebrain differentiation in vitro.

Takata N, Sakakura E, Sasai Y.

In Vitro Cell Dev Biol Anim. 2016 Mar;52(3):374-82. doi: 10.1007/s11626-015-9975-y. Epub 2015 Nov 12.

19.

Development of Novel Polymeric Prodrugs Synthesized by Mechanochemical Solid-State Copolymerization of Hydroxyethylcellulose and Vinyl Monomers.

Doi N, Sasai Y, Yamauchi Y, Adachi T, Kuzuya M, Kondo S.

Chem Pharm Bull (Tokyo). 2015;63(12):992-7. doi: 10.1248/cpb.c15-00497. Epub 2015 Oct 1.

20.

Modeling cell apoptosis for simulating three-dimensional multicellular morphogenesis based on a reversible network reconnection framework.

Okuda S, Inoue Y, Eiraku M, Adachi T, Sasai Y.

Biomech Model Mechanobiol. 2016 Aug;15(4):805-16. doi: 10.1007/s10237-015-0724-7. Epub 2015 Sep 11.

PMID:
26361766
21.

Rho-Signaling-Directed YAP/TAZ Activity Underlies the Long-Term Survival and Expansion of Human Embryonic Stem Cells.

Ohgushi M, Minaguchi M, Sasai Y.

Cell Stem Cell. 2015 Oct 1;17(4):448-61. doi: 10.1016/j.stem.2015.07.009. Epub 2015 Aug 27.

22.

Novel pH-responsive polymeric micelles prepared through self-assembly of amphiphilic block copolymer with poly-4-vinylpyridine block synthesized by mechanochemical solid-state polymerization.

Kondo S, Asano Y, Koizumi N, Tatematsu K, Sawama Y, Sasai Y, Yamauchi Y, Kuzuya M, Kurosawa S.

Chem Pharm Bull (Tokyo). 2015;63(7):489-94. doi: 10.1248/cpb.c14-00869.

23.

Comparative, transcriptome analysis of self-organizing optic tissues.

Andrabi M, Kuraku S, Takata N, Sasai Y, Love NR.

Sci Data. 2015 Jun 23;2:150030. doi: 10.1038/sdata.2015.30. eCollection 2015.

24.

Protracted anaphylaxis developed after peginterferon α-2a administration for chronic hepatitis C.

Sakatani A, Doi Y, Matsuda T, Sasai Y, Nishida N, Sakamoto M, Uenoyama N, Matsumoto Y, Kinoshita K.

World J Gastroenterol. 2015 Mar 7;21(9):2826-9. doi: 10.3748/wjg.v21.i9.2826.

25.

Generation of a ciliary margin-like stem cell niche from self-organizing human retinal tissue.

Kuwahara A, Ozone C, Nakano T, Saito K, Eiraku M, Sasai Y.

Nat Commun. 2015 Feb 19;6:6286. doi: 10.1038/ncomms7286.

PMID:
25695148
26.

Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells.

Merkle FT, Maroof A, Wataya T, Sasai Y, Studer L, Eggan K, Schier AF.

Development. 2015 Feb 15;142(4):633-43. doi: 10.1242/dev.117978.

27.

Self-organization of polarized cerebellar tissue in 3D culture of human pluripotent stem cells.

Muguruma K, Nishiyama A, Kawakami H, Hashimoto K, Sasai Y.

Cell Rep. 2015 Feb 3;10(4):537-50. doi: 10.1016/j.celrep.2014.12.051. Epub 2015 Jan 29.

28.

Impact of oceanic-scale interactions on the seasonal modulation of ocean dynamics by the atmosphere.

Sasaki H, Klein P, Qiu B, Sasai Y.

Nat Commun. 2014 Dec 15;5:5636. doi: 10.1038/ncomms6636.

29.

Vertex dynamics simulations of viscosity-dependent deformation during tissue morphogenesis.

Okuda S, Inoue Y, Eiraku M, Adachi T, Sasai Y.

Biomech Model Mechanobiol. 2015 Apr;14(2):413-25. doi: 10.1007/s10237-014-0613-5. Epub 2014 Sep 17.

PMID:
25227116
30.

Retraction: Stimulus-triggered fate conversion of somatic cells into pluripotency.

Obokata H, Wakayama T, Sasai Y, Kojima K, Vacanti MP, Niwa H, Yamato M, Vacanti CA.

Nature. 2014 Jul 3;511(7507):112. doi: 10.1038/nature13598. No abstract available.

PMID:
24990753
31.

Retraction: Bidirectional developmental potential in reprogrammed cells with acquired pluripotency.

Obokata H, Sasai Y, Niwa H, Kadota M, Andrabi M, Takata N, Tokoro M, Terashita Y, Yonemura S, Vacanti CA, Wakayama T.

Nature. 2014 Jul 3;511(7507):112. doi: 10.1038/nature13599. No abstract available.

PMID:
24990752
32.

Transplantation of embryonic and induced pluripotent stem cell-derived 3D retinal sheets into retinal degenerative mice.

Assawachananont J, Mandai M, Okamoto S, Yamada C, Eiraku M, Yonemura S, Sasai Y, Takahashi M.

Stem Cell Reports. 2014 Apr 24;2(5):662-74. doi: 10.1016/j.stemcr.2014.03.011. eCollection 2014 May 6.

33.

Cultivation of corneal endothelial cells on a pericellular matrix prepared from human decidua-derived mesenchymal cells.

Numata R, Okumura N, Nakahara M, Ueno M, Kinoshita S, Kanematsu D, Kanemura Y, Sasai Y, Koizumi N.

PLoS One. 2014 Feb 5;9(2):e88169. doi: 10.1371/journal.pone.0088169. eCollection 2014.

34.

Bidirectional developmental potential in reprogrammed cells with acquired pluripotency.

Obokata H, Sasai Y, Niwa H, Kadota M, Andrabi M, Takata N, Tokoro M, Terashita Y, Yonemura S, Vacanti CA, Wakayama T.

Nature. 2014 Jan 30;505(7485):676-80. doi: 10.1038/nature12969. Retraction in: Obokata H, Sasai Y, Niwa H, Kadota M, Andrabi M, Takata N, Tokoro M, Terashita Y, Yonemura S, Vacanti CA, Wakayama T. Nature. 2014 Jul 3;511(7507):112.

PMID:
24476891
35.

Stimulus-triggered fate conversion of somatic cells into pluripotency.

Obokata H, Wakayama T, Sasai Y, Kojima K, Vacanti MP, Niwa H, Yamato M, Vacanti CA.

Nature. 2014 Jan 30;505(7485):641-7. doi: 10.1038/nature12968. Retraction in: Obokata H, Wakayama T, Sasai Y, Kojima K, Vacanti MP, Niwa H, Yamato M, Vacanti CA. Nature. 2014 Jul 3;511(7507):112.

PMID:
24476887
36.

FGFR1-Frs2/3 signalling maintains sensory progenitors during inner ear hair cell formation.

Ono K, Kita T, Sato S, O'Neill P, Mak SS, Paschaki M, Ito M, Gotoh N, Kawakami K, Sasai Y, Ladher RK.

PLoS Genet. 2014 Jan;10(1):e1004118. doi: 10.1371/journal.pgen.1004118. Epub 2014 Jan 23.

37.

Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex.

Kadoshima T, Sakaguchi H, Nakano T, Soen M, Ando S, Eiraku M, Sasai Y.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20284-9. doi: 10.1073/pnas.1315710110. Epub 2013 Nov 25. Erratum in: Proc Natl Acad Sci U S A. 2014 May 20;111(20):7498.

38.

A large hydrothermal reservoir beneath Taal Volcano (Philippines) revealed by magnetotelluric observations and its implications to the volcanic activity.

Alanis PK, Yamaya Y, Takeuchi A, Sasai Y, Okada Y, Nagao T.

Proc Jpn Acad Ser B Phys Biol Sci. 2013;89(8):383-9.

39.

Scaling of dorsal-ventral patterning by embryo size-dependent degradation of Spemann's organizer signals.

Inomata H, Shibata T, Haraguchi T, Sasai Y.

Cell. 2013 Jun 6;153(6):1296-311. doi: 10.1016/j.cell.2013.05.004.

40.

Apical contractility in growing epithelium supports robust maintenance of smooth curvatures against cell-division-induced mechanical disturbance.

Okuda S, Inoue Y, Eiraku M, Sasai Y, Adachi T.

J Biomech. 2013 Jun 21;46(10):1705-13. doi: 10.1016/j.jbiomech.2013.03.035. Epub 2013 May 12.

PMID:
23676291
41.

Use of "MGE enhancers" for labeling and selection of embryonic stem cell-derived medial ganglionic eminence (MGE) progenitors and neurons.

Chen YJ, Vogt D, Wang Y, Visel A, Silberberg SN, Nicholas CR, Danjo T, Pollack JL, Pennacchio LA, Anderson S, Sasai Y, Baraban SC, Kriegstein AR, Alvarez-Buylla A, Rubenstein JL.

PLoS One. 2013 May 1;8(5):e61956. doi: 10.1371/journal.pone.0061956. Print 2013.

42.

Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development.

Nicholas CR, Chen J, Tang Y, Southwell DG, Chalmers N, Vogt D, Arnold CM, Chen YJ, Stanley EG, Elefanty AG, Sasai Y, Alvarez-Buylla A, Rubenstein JL, Kriegstein AR.

Cell Stem Cell. 2013 May 2;12(5):573-86. doi: 10.1016/j.stem.2013.04.005.

43.

Next-generation regenerative medicine: organogenesis from stem cells in 3D culture.

Sasai Y.

Cell Stem Cell. 2013 May 2;12(5):520-30. doi: 10.1016/j.stem.2013.04.009.

44.

Feeder-free generation and long-term culture of human induced pluripotent stem cells using pericellular matrix of decidua derived mesenchymal cells.

Fukusumi H, Shofuda T, Kanematsu D, Yamamoto A, Suemizu H, Nakamura M, Yamasaki M, Ohgushi M, Sasai Y, Kanemura Y.

PLoS One. 2013;8(1):e55226. doi: 10.1371/journal.pone.0055226. Epub 2013 Jan 31.

45.

Cytosystems dynamics in self-organization of tissue architecture.

Sasai Y.

Nature. 2013 Jan 17;493(7432):318-26. doi: 10.1038/nature11859. Review.

PMID:
23325214
46.

Robust formation and maintenance of continuous stratified cortical neuroepithelium by laminin-containing matrix in mouse ES cell culture.

Nasu M, Takata N, Danjo T, Sakaguchi H, Kadoshima T, Futaki S, Sekiguchi K, Eiraku M, Sasai Y.

PLoS One. 2012;7(12):e53024. doi: 10.1371/journal.pone.0053024. Epub 2012 Dec 31.

47.

Modeling cell proliferation for simulating three-dimensional tissue morphogenesis based on a reversible network reconnection framework.

Okuda S, Inoue Y, Eiraku M, Sasai Y, Adachi T.

Biomech Model Mechanobiol. 2013 Oct;12(5):987-96. doi: 10.1007/s10237-012-0458-8. Epub 2012 Nov 30.

PMID:
23196700
48.
49.

In vitro organogenesis in three dimensions: self-organising stem cells.

Sasai Y, Eiraku M, Suga H.

Development. 2012 Nov;139(22):4111-21. doi: 10.1242/dev.079590. Review.

50.

Advanced glycation endproducts stimulate renal epithelial cells to release chemokines that recruit macrophages, leading to renal fibrosis.

Sasai Y, Iwakawa K, Yanagida K, Shen Y, Hosono T, Ariga T, Seki T.

Biosci Biotechnol Biochem. 2012;76(9):1741-5. Epub 2012 Sep 7.

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