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Items: 1 to 50 of 79

1.

Prominin-1 Modulates Rho/ROCK-Mediated Membrane Morphology and Calcium-Dependent Intracellular Chloride Flux.

Hori A, Nishide K, Yasukuni Y, Haga K, Kakuta W, Ishikawa Y, Hayes MJ, Ohnuma SI, Kiyonari H, Kimura K, Kondo T, Sasai N.

Sci Rep. 2019 Nov 4;9(1):15911. doi: 10.1038/s41598-019-52040-9.

2.

Negative Regulation of mTOR Signaling Restricts Cell Proliferation in the Floor Plate.

Kadoya M, Sasai N.

Front Neurosci. 2019 Sep 25;13:1022. doi: 10.3389/fnins.2019.01022. eCollection 2019.

3.

Efficacy and Safety of Alogliptin in Elderly Patients With Type 2 Diabetes Mellitus.

Takeda H, Sasai N, Ito S, Obana M, Takuma T, Takai M, Kaneshige H, Machimura H, Kanamori A, Matsuba I.

J Clin Med Res. 2019 Sep;11(9):651-663. doi: 10.14740/jocmr3953. Epub 2019 Sep 1.

4.

Jump Exercise and Food Restriction on Bone Parameters in Young Female Rats.

Aikawa Y, Wakasugi Y, Narukawa T, Yamashita T, Sasai N, Umemura Y, Omi N, Ohtsuki M.

Calcif Tissue Int. 2019 Nov;105(5):557-566. doi: 10.1007/s00223-019-00601-5. Epub 2019 Aug 29.

PMID:
31468066
5.

GPR17 is an essential regulator for the temporal adaptation of sonic hedgehog signalling in neural tube development.

Yatsuzuka A, Hori A, Kadoya M, Matsuo-Takasaki M, Kondo T, Sasai N.

Development. 2019 Sep 12;146(17). pii: dev176784. doi: 10.1242/dev.176784.

PMID:
31444216
6.

NUPR1 acts as a pro-survival factor in human bone marrow-derived mesenchymal stem cells and is induced by the hypoxia mimetic reagent deferoxamine.

Matsunaga K, Fujisawa K, Takami T, Burganova G, Sasai N, Matsumoto T, Yamamoto N, Sakaida I.

J Clin Biochem Nutr. 2019 May;64(3):209-216. doi: 10.3164/jcbn.18-112. Epub 2019 Mar 23.

7.

Efficacy and Safety of Adding Sitagliptin in Type 2 Diabetes Patients on Insulin: Age-Stratified Comparison at One Year in the ASSIST-K Study.

Takai M, Ishikawa M, Maeda H, Kanamori A, Kubota A, Amemiya H, Iizuka T, Iemitsu K, Iwasaki T, Uehara G, Umezawa S, Obana M, Kaneshige H, Kaneshiro M, Kawata T, Sasai N, Saito T, Takuma T, Takeda H, Tanaka K, Nakajima S, Hoshino K, Honda S, Machimura H, Matoba K, Minagawa F, Minami N, Miyairi Y, Mokubo A, Motomiya T, Waseda M, Miyakawa M, Terauchi Y, Tanaka Y, Matsuba I.

J Clin Med Res. 2019 May;11(5):311-320. doi: 10.14740/jocmr3677. Epub 2019 Apr 14.

8.

Clonal change of methicillin-resistant Staphylococcus aureus isolated from patients with impetigo in Kagawa, Japan.

Sasai N, Nakaminami H, Iwasaki M, Iwao M, Misegawa K, Hasui M, Sato M, Yamamoto S, Yoshida T, Asano T, Senoue M, Ikeda M, Noguchi N.

J Dermatol. 2019 Apr;46(4):301-307. doi: 10.1111/1346-8138.14820. Epub 2019 Feb 25.

PMID:
30803017
9.

Change in genotype of methicillin-resistant Staphylococcus aureus (MRSA) affects the antibiogram of hospital-acquired MRSA.

Harada D, Nakaminami H, Miyajima E, Sugiyama T, Sasai N, Kitamura Y, Tamura T, Kawakubo T, Noguchi N.

J Infect Chemother. 2018 Jul;24(7):563-569. doi: 10.1016/j.jiac.2018.03.004. Epub 2018 Apr 6.

PMID:
29628385
10.

Control of neural crest induction by MarvelD3-mediated attenuation of JNK signalling.

Vacca B, Sanchez-Heras E, Steed E, Busson SL, Balda MS, Ohnuma SI, Sasai N, Mayor R, Matter K.

Sci Rep. 2018 Jan 19;8(1):1204. doi: 10.1038/s41598-018-19579-5.

11.

Effectiveness of Ipragliflozin for Reducing Hemoglobin A1c in Patients With a Shorter Type 2 Diabetes Duration: Interim Report of the ASSIGN-K Study.

Iemitsu K, Kawata T, Iizuka T, Takihata M, Takai M, Nakajima S, Minami N, Umezawa S, Kanamori A, Takeda H, Ito S, Kikuchi T, Amemiya H, Kaneshiro M, Mokubo A, Takuma T, Machimura H, Tanaka K, Asakura T, Kubota A, Aoyanagi S, Hoshino K, Ishikawa M, Matsuzawa Y, Obana M, Sasai N, Kaneshige H, Minagawa F, Saito T, Shinoda K, Miyakawa M, Tanaka Y, Terauchi Y, Matsuba I.

J Clin Med Res. 2017 Sep;9(9):793-801. doi: 10.14740/jocmr3116w. Epub 2017 Jul 27.

12.

Ipragliflozin Improves Glycemic Control and Decreases Body Fat in Patients With Type 2 Diabetes Mellitus.

Kawata T, Iizuka T, Iemitsu K, Takihata M, Takai M, Nakajima S, Minami N, Umezawa S, Kanamori A, Takeda H, Ito S, Kikuchi T, Amemiya H, Kaneshiro M, Mokubo A, Takuma T, Machimura H, Tanaka K, Asakura T, Kubota A, Aoyanagi S, Hoshino K, Ishikawa M, Matsuzawa Y, Obana M, Sasai N, Kaneshige H, Minagawa F, Saito T, Shinoda K, Miyakawa M, Tanaka Y, Terauchi Y, Matsuba I.

J Clin Med Res. 2017 Jul;9(7):586-595. doi: 10.14740/jocmr3038w. Epub 2017 May 22.

13.

MarvelD3 regulates the c-Jun N-terminal kinase pathway during eye development in Xenopus.

Vacca B, Sanchez-Heras E, Steed E, Balda MS, Ohnuma SI, Sasai N, Mayor R, Matter K.

Biol Open. 2016 Nov 15;5(11):1631-1641. doi: 10.1242/bio.018945.

14.

Factors Influencing Changes in Hemoglobin A1c and Body Weight During Treatment of Type 2 Diabetes With Ipragliflozin: Interim Analysis of the ASSIGN-K Study.

Iemitsu K, Iizuka T, Takihata M, Takai M, Nakajima S, Minami N, Umezawa S, Kanamori A, Takeda H, Kawata T, Ito S, Kikuchi T, Amemiya H, Kaneshiro M, Mokubo A, Takuma T, Machimura H, Tanaka K, Asakura T, Kubota A, Aoyagi S, Hoshino K, Ishikawa M, Obana M, Sasai N, Kaneshige H, Miyakawa M, Tanaka Y, Terauchi Y, Matsuba I.

J Clin Med Res. 2016 May;8(5):373-8. doi: 10.14740/jocmr2492w. Epub 2016 Mar 20.

15.

Neural Progenitors Adopt Specific Identities by Directly Repressing All Alternative Progenitor Transcriptional Programs.

Kutejova E, Sasai N, Shah A, Gouti M, Briscoe J.

Dev Cell. 2016 Mar 21;36(6):639-53. doi: 10.1016/j.devcel.2016.02.013. Epub 2016 Mar 10.

16.

Correction: Efficacy and Safety of Ipragliflozin in Japanese Patients With Type 2 Diabetes: Interim Outcome of the ASSIGN-K Study.

Iizuka T, Iemitsu K, Takihata M, Takai M, Nakajima S, Minami N, Umezawa S, Kanamori A, Takeda H, Kawata T, Ito S, Kikuchi T, Amemiya H, Kaneshiro M, Mokubo A, Takuma T, Machimura H, Tanaka K, Asakura T, Kubota A, Aoyagi S, Hoshino K, Ishikawa M, Matsuzawa Y, Obana M, Sasai N, Kaneshige H, Minagawa F, Saito T, Shinoda K, Miyakawa M, Tanaka Y, Terauchi Y, Matsuba I.

J Clin Med Res. 2016 Mar;8(3):267. doi: 10.14740/jocmr2417wc1. Epub 2016 Jan 26.

17.

Efficacy and Safety of Alogliptin in Patients With Type 2 Diabetes: Analysis of the ATTAK-J Study.

Takeda H, Sasai N, Ito S, Obana M, Takuma T, Takai M, Kaneshige H, Machimura H, Kanamori A, Nakajima K, Matsuba I.

J Clin Med Res. 2016 Feb;8(2):130-40. doi: 10.14740/jocmr2418w. Epub 2015 Dec 28.

18.

Efficacy and Safety of Ipragliflozin in Japanese Patients With Type 2 Diabetes: Interim Outcome of the ASSIGN-K Study.

Iizuka T, Iemitsu K, Takihata M, Takai M, Nakajima S, Minami N, Umezawa S, Kanamori A, Takeda H, Kawata T, Ito S, Kikuchi T, Amemiya H, Kaneshiro M, Mokubo A, Takuma T, Machimura H, Tanaka K, Asakura T, Kubota A, Aoyagi S, Hoshino K, Ishikawa M, Matsuzawa Y, Obana M, Sasai N, Kaneshige H, Minagawa F, Saito T, Shinoda K, Miyakawa M, Tanaka Y, Terauchi Y, Matsuba I.

J Clin Med Res. 2016 Feb;8(2):116-25. doi: 10.14740/jocmr2417w. Epub 2015 Dec 28. Erratum in: J Clin Med Res. 2016 Mar;8(3):267.

19.

Autosomal-Dominant Corneal Endothelial Dystrophies CHED1 and PPCD1 Are Allelic Disorders Caused by Non-coding Mutations in the Promoter of OVOL2.

Davidson AE, Liskova P, Evans CJ, Dudakova L, Nosková L, Pontikos N, Hartmannová H, Hodaňová K, Stránecký V, Kozmík Z, Levis HJ, Idigo N, Sasai N, Maher GJ, Bellingham J, Veli N, Ebenezer ND, Cheetham ME, Daniels JT, Thaung CM, Jirsova K, Plagnol V, Filipec M, Kmoch S, Tuft SJ, Hardcastle AJ.

Am J Hum Genet. 2016 Jan 7;98(1):75-89. doi: 10.1016/j.ajhg.2015.11.018. Epub 2015 Dec 31.

20.

The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway.

Luehders K, Sasai N, Davaapil H, Kurosawa-Yoshida M, Hiura H, Brah T, Ohnuma S.

Development. 2015 Oct 1;142(19):3351-61. doi: 10.1242/dev.124438.

21.

Two-year assessment of the efficacy and safety of sitagliptin in elderly patients with type 2 diabetes: Post hoc analysis of the ASSET-K study.

Umezawa S, Kubota A, Maeda H, Kanamori A, Matoba K, Jin Y, Minagawa F, Obana M, Iemitsu K, Ito S, Amamiya H, Kaneshiro M, Takai M, Kaneshige H, Hoshino K, Ishikawa M, Minami N, Takuma T, Sasai N, Aoyagi S, Kawata T, Mokubo A, Miyairi Y, Takeda H, Honda S, Machimura H, Motomiya T, Waseda M, Naka Y, Tanaka Y, Terauchi Y, Matsuba I.

BMC Endocr Disord. 2015 Jul 3;15:34. doi: 10.1186/s12902-015-0033-2.

22.

Factors Predicting Therapeutic Efficacy of Combination Treatment With Sitagliptin and Insulin in Type 2 Diabetic Patients: The ASSIST-K Study.

Ishikawa M, Takai M, Maeda H, Kanamori A, Kubota A, Amemiya H, Iizuka T, Iemitsu K, Iwasaki T, Uehara G, Umezawa S, Obana M, Kaneshige H, Kaneshiro M, Kawata T, Sasai N, Saito T, Takuma T, Takeda H, Tanaka K, Tsurui N, Nakajima S, Hoshino K, Honda S, Machimura H, Matoba K, Minagawa F, Minami N, Miyairi Y, Mokubo A, Motomiya T, Waseda M, Miyakawa M, Naka Y, Terauchi Y, Tanaka Y, Matsuba I.

J Clin Med Res. 2015 Aug;7(8):607-12. doi: 10.14740/jocmr2149w. Epub 2015 Jun 9.

23.

Genetic background and light-dependent progression of photoreceptor cell degeneration in Prominin-1 knockout mice.

Dellett M, Sasai N, Nishide K, Becker S, Papadaki V, Limb GA, Moore AT, Kondo T, Ohnuma S.

Invest Ophthalmol Vis Sci. 2014 Nov 20;56(1):164-76. doi: 10.1167/iovs.14-15479.

PMID:
25414197
24.

Integration of signals along orthogonal axes of the vertebrate neural tube controls progenitor competence and increases cell diversity.

Sasai N, Kutejova E, Briscoe J.

PLoS Biol. 2014 Jul 15;12(7):e1001907. doi: 10.1371/journal.pbio.1001907. eCollection 2014 Jul.

25.

Effects of irbesartan on serum uric acid levels in patients with hypertension and diabetes.

Nakamura M, Sasai N, Hisatome I, Ichida K.

Clin Pharmacol. 2014 May 3;6:79-86. doi: 10.2147/CPAA.S61462. eCollection 2014.

26.

Safety and efficacy of adding sitagliptin to insulin in patients with type 2 diabetes: the ASSIST-K study.

Takai M, Ishikawa M, Maeda H, Kanamori A, Kubota A, Amemiya H, Iizuka T, Iemitsu K, Iwasaki T, Uehara G, Umezawa S, Obana M, Kaneshige H, Kaneshiro M, Kawata T, Sasai N, Saito T, Takuma T, Takeda H, Tanaka K, Tsurui N, Nakajima S, Hoshino K, Honda S, Machimura H, Matoba K, Minagawa F, Minami N, Miyairi Y, Mokubo A, Motomiya T, Waseda M, Miyakawa M, Naka Y, Terauchi Y, Tanaka Y, Matsuba I.

Diabetes Res Clin Pract. 2014 Mar;103(3):e30-3. doi: 10.1016/j.diabres.2013.12.045. Epub 2014 Jan 6.

PMID:
24525293
27.

Valproic acid silencing of ascl1b/Ascl1 results in the failure of serotonergic differentiation in a zebrafish model of fetal valproate syndrome.

Jacob J, Ribes V, Moore S, Constable SC, Sasai N, Gerety SS, Martin DJ, Sergeant CP, Wilkinson DG, Briscoe J.

Dis Model Mech. 2014 Jan;7(1):107-17. doi: 10.1242/dmm.013219. Epub 2013 Oct 17.

28.

The transcriptional cofactor MCAF1/ATF7IP is involved in histone gene expression and cellular senescence.

Sasai N, Saitoh N, Saitoh H, Nakao M.

PLoS One. 2013 Jul 30;8(7):e68478. doi: 10.1371/journal.pone.0068478. Print 2013.

29.

Primary cilia and graded Sonic Hedgehog signaling.

Sasai N, Briscoe J.

Wiley Interdiscip Rev Dev Biol. 2012 Sep-Oct;1(5):753-72. doi: 10.1002/wdev.43. Epub 2012 Apr 4. Review.

PMID:
23799571
30.

An inducible transgene expression system for zebrafish and chick.

Gerety SS, Breau MA, Sasai N, Xu Q, Briscoe J, Wilkinson DG.

Development. 2013 May;140(10):2235-43. doi: 10.1242/dev.091520.

31.

[Epigenomic modification as therapeutic targets of cancer].

Tomita S, Sasai N, Hino S, Nakao M.

Nihon Rinsho. 2012 Nov;70 Suppl 8:91-7. Japanese. No abstract available.

PMID:
23513818
32.

Retinoid acid specifies neuronal identity through graded expression of Ascl1.

Jacob J, Kong J, Moore S, Milton C, Sasai N, Gonzalez-Quevedo R, Terriente J, Imayoshi I, Kageyama R, Wilkinson DG, Novitch BG, Briscoe J.

Curr Biol. 2013 Mar 4;23(5):412-8. doi: 10.1016/j.cub.2013.01.046. Epub 2013 Feb 14. Erratum in: Curr Biol. 2013 Apr 8;23(7):632. Kageyama, Ryoichoro [corrected to Kageyama, Ryoichiro].

33.

Efficacy and safety of sitagliptin monotherapy and combination therapy in Japanese type 2 diabetes patients.

Kubota A, Maeda H, Kanamori A, Matoba K, Jin Y, Minagawa F, Obana M, Iemitsu K, Ito S, Amamiya H, Kaneshiro M, Takai M, Kaneshige H, Hoshino K, Ishikawa M, Minami N, Takuma T, Sasai N, Aoyagi S, Kawata T, Mokubo A, Takeda H, Honda S, Machimura H, Motomiya T, Waseda M, Naka Y, Tanaka Y, Terauchi Y, Matsuba I.

J Diabetes Investig. 2012 Dec 20;3(6):503-9. doi: 10.1111/j.2040-1124.2012.00221.x.

34.

Pleiotropic effects of sitagliptin in the treatment of type 2 diabetes mellitus patients.

Kubota A, Maeda H, Kanamori A, Matoba K, Jin Y, Minagawa F, Obana M, Iemitsu K, Ito S, Amemiya H, Kaneshiro M, Takai M, Kaneshige H, Hoshino K, Ishikawa M, Minami N, Takuma T, Sasai N, Aoyagi S, Kawata T, Mokubo A, Takeda H, Honda S, Machimura H, Motomiya T, Waseda M, Naka Y, Tanaka Y, Terauchi Y, Matsuba I.

J Clin Med Res. 2012 Oct;4(5):309-13. Epub 2012 Sep 12.

35.

Cross-sectional survey of diabetic neuropathy in Kanagawa and clinical significance of a touch test using tissue paper.

Jin Y, Kanamori A, Ito S, Matoba K, Miyakawa M, Kaneshige H, Obana M, Takai M, Takeda H, Machimura H, Minami N, Kawata T, Honda S, Aoyagi S, Amemiya H, Sasai N, Nakayama M, Naka Y, Terauchi Y, Matsuba I.

J Diabetes Investig. 2012 Jun 6;3(3):252-8. doi: 10.1111/j.2040-1124.2011.00174.x.

36.

Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube.

Balaskas N, Ribeiro A, Panovska J, Dessaud E, Sasai N, Page KM, Briscoe J, Ribes V.

Cell. 2012 Jan 20;148(1-2):273-84. doi: 10.1016/j.cell.2011.10.047.

37.

The role of methyl-binding proteins in chromatin organization and epigenome maintenance.

Fournier A, Sasai N, Nakao M, Defossez PA.

Brief Funct Genomics. 2012 May;11(3):251-64. doi: 10.1093/bfgp/elr040. Epub 2011 Dec 19. Review.

PMID:
22184333
38.

Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened.

Chen Y, Sasai N, Ma G, Yue T, Jia J, Briscoe J, Jiang J.

PLoS Biol. 2011 Jun;9(6):e1001083. doi: 10.1371/journal.pbio.1001083. Epub 2011 Jun 14.

39.

Intrinsic transition of embryonic stem-cell differentiation into neural progenitors.

Kamiya D, Banno S, Sasai N, Ohgushi M, Inomata H, Watanabe K, Kawada M, Yakura R, Kiyonari H, Nakao K, Jakt LM, Nishikawa S, Sasai Y.

Nature. 2011 Feb 24;470(7335):503-9. doi: 10.1038/nature09726. Epub 2011 Feb 16.

PMID:
21326203
40.

Jiraiya attenuates BMP signaling by interfering with type II BMP receptors in neuroectodermal patterning.

Aramaki T, Sasai N, Yakura R, Sasai Y.

Dev Cell. 2010 Oct 19;19(4):547-61. doi: 10.1016/j.devcel.2010.09.001.

41.

The human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNA.

Laget S, Joulie M, Le Masson F, Sasai N, Christians E, Pradhan S, Roberts RJ, Defossez PA.

PLoS One. 2010 Aug 6;5(8):e11982. doi: 10.1371/journal.pone.0011982.

42.

Relationship between a chronically painful trapezius muscle and its metabolic state analyzed with PET/CT.

Takiguchi S, Maekawa K, Ono T, Sasai N, Kaji M, Clark GT, Kuboki T.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Jul;110(1):54-61. doi: 10.1016/j.tripleo.2010.02.028.

PMID:
20610298
43.

Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog.

Dessaud E, Ribes V, Balaskas N, Yang LL, Pierani A, Kicheva A, Novitch BG, Briscoe J, Sasai N.

PLoS Biol. 2010 Jun 1;8(6):e1000382. doi: 10.1371/journal.pbio.1000382.

44.

Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube.

Ribes V, Balaskas N, Sasai N, Cruz C, Dessaud E, Cayuso J, Tozer S, Yang LL, Novitch B, Marti E, Briscoe J.

Genes Dev. 2010 Jun 1;24(11):1186-200. doi: 10.1101/gad.559910.

45.

Sequence-specific recognition of methylated DNA by human zinc-finger proteins.

Sasai N, Nakao M, Defossez PA.

Nucleic Acids Res. 2010 Aug;38(15):5015-22. doi: 10.1093/nar/gkq280. Epub 2010 Apr 19.

46.

Involvement of PI3K/Akt/TOR pathway in stretch-induced hypertrophy of myotubes.

Sasai N, Agata N, Inoue-Miyazu M, Kawakami K, Kobayashi K, Sokabe M, Hayakawa K.

Muscle Nerve. 2010 Jan;41(1):100-6. doi: 10.1002/mus.21473.

PMID:
19768770
47.

The human protein kinase HIPK2 phosphorylates and downregulates the methyl-binding transcription factor ZBTB4.

Yamada D, Pérez-Torrado R, Filion G, Caly M, Jammart B, Devignot V, Sasai N, Ravassard P, Mallet J, Sastre-Garau X, Schmitz ML, Defossez PA.

Oncogene. 2009 Jul 9;28(27):2535-44. doi: 10.1038/onc.2009.109. Epub 2009 May 18.

PMID:
19448668
48.

Many paths to one goal? The proteins that recognize methylated DNA in eukaryotes.

Sasai N, Defossez PA.

Int J Dev Biol. 2009;53(2-3):323-34. doi: 10.1387/ijdb.082652ns. Review.

49.

Repetitive stretch suppresses denervation-induced atrophy of soleus muscle in rats.

Agata N, Sasai N, Inoue-Miyazu M, Kawakami K, Hayakawa K, Kobayashi K, Sokabe M.

Muscle Nerve. 2009 Apr;39(4):456-62. doi: 10.1002/mus.21103.

PMID:
19260063
50.

Basic study of susceptibility-weighted imaging at 1.5T.

Matsushita T, Anami D, Arioka T, Inoue S, Kariya Y, Fujimoto M, Ida K, Sasai N, Kaji M, Kanazawa S, Joja I.

Acta Med Okayama. 2008 Jun;62(3):159-68.

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