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Items: 1 to 50 of 147

1.

Bardoxolone methyl as a novel potent antiviral agent against hepatitis B and C viruses in human hepatocyte cell culture systems.

Nio Y, Sasai M, Akahori Y, Okamura H, Hasegawa H, Oshima M, Watashi K, Wakita T, Ryo A, Tanaka Y, Hijikata M.

Antiviral Res. 2019 Jun 14;169:104537. doi: 10.1016/j.antiviral.2019.104537. [Epub ahead of print]

PMID:
31207277
2.

CXCR4 regulates Plasmodium development in mouse and human hepatocytes.

Bando H, Pradipta A, Iwanaga S, Okamoto T, Okuzaki D, Tanaka S, Vega-Rodríguez J, Lee Y, Ma JS, Sakaguchi N, Soga A, Fukumoto S, Sasai M, Matsuura Y, Yuda M, Jacobs-Lorena M, Yamamoto M.

J Exp Med. 2019 Jun 12. pii: jem.20182227. doi: 10.1084/jem.20182227. [Epub ahead of print]

PMID:
31189656
3.

Alcohol consumption and incident dementia in older Japanese adults: The Okayama Study.

Liu Y, Mitsuhashi T, Yamakawa M, Sasai M, Tsuda T, Doi H, Hamada J.

Geriatr Gerontol Int. 2019 Jun 7. doi: 10.1111/ggi.13694. [Epub ahead of print]

PMID:
31173440
4.

Toxoplasma Effector GRA15-Dependent Suppression of IFN-γ-Induced Antiparasitic Response in Human Neurons.

Bando H, Lee Y, Sakaguchi N, Pradipta A, Sakamoto R, Tanaka S, Ma JS, Sasai M, Yamamoto M.

Front Cell Infect Microbiol. 2019 May 1;9:140. doi: 10.3389/fcimb.2019.00140. eCollection 2019.

5.

Health risk management behaviors and related factors among Japanese university students participating in short-term study abroad programs.

Yamakawa M, Tanaka Y, Sasai M.

J Infect Chemother. 2019 May 16. pii: S1341-321X(19)30119-9. doi: 10.1016/j.jiac.2019.04.015. [Epub ahead of print]

PMID:
31105000
6.

Physical activity and incident dementia in older Japanese adults: The Okayama study.

Liu Y, Mitsuhashi T, Yamakawa M, Sasai M, Tsuda T, Doi H, Hamada J.

Int J Geriatr Psychiatry. 2019 May 2. doi: 10.1002/gps.5135. [Epub ahead of print]

PMID:
31050010
7.

Polygon-like luminal configuration captured by intracoronary optical frequency domain imaging of a spontaneous coronary spasm in an ST-elevation myocardial infarction patient.

Takei Y, Mori H, Sone H, Tashiro K, Sasai M, Sato T, Suzuki H.

Coron Artery Dis. 2019 Jun;30(4):314-315. doi: 10.1097/MCA.0000000000000728. No abstract available.

PMID:
30883429
8.

Single nucleosome imaging reveals loose genome chromatin networks via active RNA polymerase II.

Nagashima R, Hibino K, Ashwin SS, Babokhov M, Fujishiro S, Imai R, Nozaki T, Tamura S, Tani T, Kimura H, Shribak M, Kanemaki MT, Sasai M, Maeshima K.

J Cell Biol. 2019 May 6;218(5):1511-1530. doi: 10.1083/jcb.201811090. Epub 2019 Mar 1.

9.

Neointimal erosion resulting in very-late stent thrombosis.

Mori H, Sone H, Takei Y, Tashiro K, Sasai M, Maeda A, Sato T, Suzuki H.

Coron Artery Dis. 2019 Jun;30(4):312-313. doi: 10.1097/MCA.0000000000000717. No abstract available.

PMID:
30694821
10.

Effects of Stochastic Single-Molecule Reactions on Coherent Ensemble Oscillations in the KaiABC Circadian Clock.

Sasai M.

J Phys Chem B. 2019 Jan 24;123(3):702-713. doi: 10.1021/acs.jpcb.8b10584. Epub 2019 Jan 10.

PMID:
30629448
11.

Angioscopic imaging one month after the implantation of a drug-eluting stent following drug-coated balloon treatment.

Sone H, Mori H, Sato T, Takei Y, Tashiro K, Sasai M, Suzuki H.

Int J Cardiol Heart Vasc. 2018 Nov 6;21:111-112. doi: 10.1016/j.ijcha.2018.10.007. eCollection 2018 Dec. No abstract available.

12.

Measles vaccination status among Japanese university students participating in short-term study abroad programs.

Yamakawa M, Sasai M, Ono M, Tsuda T.

Travel Med Infect Dis. 2019 Jan - Feb;27:131-132. doi: 10.1016/j.tmaid.2018.10.008. Epub 2018 Oct 9. No abstract available.

PMID:
30312733
13.

GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections.

Kim JK, Kim YS, Lee HM, Jin HS, Neupane C, Kim S, Lee SH, Min JJ, Sasai M, Jeong JH, Choe SK, Kim JM, Yamamoto M, Choy HE, Park JB, Jo EK.

Nat Commun. 2018 Oct 10;9(1):4184. doi: 10.1038/s41467-018-06487-5.

14.

Inducible Nitric Oxide Synthase Is a Key Host Factor for Toxoplasma GRA15-Dependent Disruption of the Gamma Interferon-Induced Antiparasitic Human Response.

Bando H, Lee Y, Sakaguchi N, Pradipta A, Ma JS, Tanaka S, Cai Y, Liu J, Shen J, Nishikawa Y, Sasai M, Yamamoto M.

MBio. 2018 Oct 9;9(5). pii: e01738-18. doi: 10.1128/mBio.01738-18.

15.

Toxoplasma Effector TgIST Targets Host IDO1 to Antagonize the IFN-γ-Induced Anti-parasitic Response in Human Cells.

Bando H, Sakaguchi N, Lee Y, Pradipta A, Ma JS, Tanaka S, Lai DH, Liu J, Lun ZR, Nishikawa Y, Sasai M, Yamamoto M.

Front Immunol. 2018 Sep 19;9:2073. doi: 10.3389/fimmu.2018.02073. eCollection 2018.

16.

Single-molecular and ensemble-level oscillations of cyanobacterial circadian clock.

Das S, Terada TP, Sasai M.

Biophys Physicobiol. 2018 May 26;15:136-150. doi: 10.2142/biophysico.15.0_136. eCollection 2018.

17.

Orally active anti-hypertensive peptides found based on enteroendocrine cell responses to a dipeptide library.

Sasai M, Sun X, Okuda C, Nakato J, Kanamoto R, Ohinata K.

Biochem Biophys Res Commun. 2018 Sep 5;503(2):1070-1074. doi: 10.1016/j.bbrc.2018.06.118. Epub 2018 Jun 25.

PMID:
29936178
18.

Confirmed coronary spasm at the culprit vessel of plaque erosion in a patient with new-onset ventricular fibrillation.

Tashiro K, Mori H, Sone H, Takei Y, Sasai M, Maeda A, Sato T, Suzuki H.

Coron Artery Dis. 2018 Nov;29(7):603-604. doi: 10.1097/MCA.0000000000000639. No abstract available.

PMID:
29746260
19.

Effects of tongue cleaning on Ayurvedic digestive power and oral health-related quality of life: A randomized cross-over study.

Tokinobu A, Yorifuji T, Sasai M, Doi H, Tsuda T.

Complement Ther Med. 2018 Feb;36:9-13. doi: 10.1016/j.ctim.2017.11.011. Epub 2017 Nov 15.

PMID:
29458938
20.

Host immune responses to Toxoplasma gondii.

Sasai M, Pradipta A, Yamamoto M.

Int Immunol. 2018 Mar 10;30(3):113-119. doi: 10.1093/intimm/dxy004. Review.

PMID:
29408976
21.

Diarrhea and related factors among passengers on world cruises departing from Japan.

Yamakawa M, Sasai M, Kasai Y, Tsuda T, Suzuki E.

Travel Med Infect Dis. 2018 May - Jun;23:56-63. doi: 10.1016/j.tmaid.2018.01.004. Epub 2018 Jan 31.

PMID:
29366715
22.

Role of ATP Hydrolysis in Cyanobacterial Circadian Oscillator.

Das S, Terada TP, Sasai M.

Sci Rep. 2017 Dec 12;7(1):17469. doi: 10.1038/s41598-017-17717-z.

23.

Characterization of SPP inhibitors suppressing propagation of HCV and protozoa.

Hirano J, Okamoto T, Sugiyama Y, Suzuki T, Kusakabe S, Tokunaga M, Fukuhara T, Sasai M, Tougan T, Matsunaga Y, Yamashita K, Sakai Y, Yamamoto M, Horii T, Standley DM, Moriishi K, Moriya K, Koike K, Matsuura Y.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10782-E10791. doi: 10.1073/pnas.1712484114. Epub 2017 Nov 29.

24.

Safety and tolerability of selumetinib as a monotherapy, or in combination with docetaxel as second-line therapy, in Japanese patients with advanced solid malignancies or non-small cell lung cancer.

Seto T, Hirai F, Saka H, Kogure Y, Yoh K, Niho S, Fukase K, Shimada H, Sasai M, Fukino K.

Jpn J Clin Oncol. 2018 Jan 1;48(1):31-42. doi: 10.1093/jjco/hyx144.

PMID:
29136201
25.

360-degree screen-free floating 3D image in a crystal ball using a spatially imaged iris and rotational multiview DFD technologies.

Kawakami T, Date M, Sasai M, Takada H.

Appl Opt. 2017 Aug 1;56(22):6156-6167. doi: 10.1364/AO.56.006156.

PMID:
29047809
26.

Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.

Sasai M, Sakaguchi N, Ma JS, Nakamura S, Kawabata T, Bando H, Lee Y, Saitoh T, Akira S, Iwasaki A, Standley DM, Yoshimori T, Yamamoto M.

Nat Immunol. 2017 Aug;18(8):899-910. doi: 10.1038/ni.3767. Epub 2017 Jun 12.

PMID:
28604719
27.

Cooperativity and modularity in protein folding.

Sasai M, Chikenji G, Terada TP.

Biophys Physicobiol. 2016 Nov 18;13:281-293. doi: 10.2142/biophysico.13.0_281. eCollection 2016. Review.

28.

Potential role of heme metabolism in the inducible expression of heme oxygenase-1.

Takeda TA, Sasai M, Adachi Y, Ohnishi K, Fujisawa JI, Izawa S, Taketani S.

Biochim Biophys Acta Gen Subj. 2017 Jul;1861(7):1813-1824. doi: 10.1016/j.bbagen.2017.03.018. Epub 2017 Mar 24.

PMID:
28347842
29.

Heterogeneous Spatial Distribution of Transcriptional Activity in Budding Yeast Nuclei.

Tokuda N, Sasai M.

Biophys J. 2017 Feb 7;112(3):491-504. doi: 10.1016/j.bpj.2016.11.3201. Epub 2016 Dec 28.

30.

Importance of consensus region of multiple-ligand templates in a virtual screening method.

Okuno T, Kato K, Minami S, Terada TP, Sasai M, Chikenji G.

Biophys Physicobiol. 2016 Jul 14;13:149-156. eCollection 2016.

31.

Potential contribution of the hepcidin-macrophage axis to plaque vulnerability in acute myocardial infarction in human.

Sasai M, Iso Y, Mizukami T, Tomosugi N, Sambe T, Miyazaki A, Suzuki H.

Int J Cardiol. 2017 Jan 15;227:114-121. doi: 10.1016/j.ijcard.2016.11.147. Epub 2016 Nov 9.

PMID:
27855289
32.

IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.

Man SM, Karki R, Sasai M, Place DE, Kesavardhana S, Temirov J, Frase S, Zhu Q, Malireddi RKS, Kuriakose T, Peters JL, Neale G, Brown SA, Yamamoto M, Kanneganti TD.

Cell. 2016 Oct 6;167(2):382-396.e17. doi: 10.1016/j.cell.2016.09.012. Epub 2016 Sep 29.

33.

The P2X4 receptor is required for neuroprotection via ischemic preconditioning.

Ozaki T, Muramatsu R, Sasai M, Yamamoto M, Kubota Y, Fujinaka T, Yoshimine T, Yamashita T.

Sci Rep. 2016 May 13;6:25893. doi: 10.1038/srep25893.

34.

The Effect of Cilostazol on Endothelial Function as Assessed by Flow-Mediated Dilation in Patients with Coronary Artery Disease.

Mori H, Maeda A, Wakabayashi K, Sato T, Sasai M, Tashiro K, Iso Y, Ebato M, Suzuki H.

J Atheroscler Thromb. 2016 Oct 1;23(10):1168-1177. Epub 2016 May 9.

35.

Novel Hyaluronan Formulation Enhances the Efficacy of Boron Neutron Capture Therapy for Murine Mesothelioma.

Sasai M, Nakamura H, Sougawa N, Sakurai Y, Suzuki M, Lee CM.

Anticancer Res. 2016 Mar;36(3):907-11.

PMID:
26976977
36.

Priming with erythropoietin enhances cell survival and angiogenic effect of mesenchymal stem cell implantation in rat limb ischemia.

Mizukami T, Iso Y, Sato C, Sasai M, Spees JL, Toyoda M, Umezawa A, Miyazaki A, Suzuki H.

Regen Ther. 2016 Feb 13;4:1-8. doi: 10.1016/j.reth.2016.01.004. eCollection 2016 Jun.

37.

Liquid-like behavior of chromatin.

Maeshima K, Ide S, Hibino K, Sasai M.

Curr Opin Genet Dev. 2016 Apr;37:36-45. doi: 10.1016/j.gde.2015.11.006. Epub 2016 Jan 27. Review.

38.

Fibroblast growth factor-23 induces cellular senescence in human mesenchymal stem cells from skeletal muscle.

Sato C, Iso Y, Mizukami T, Otabe K, Sasai M, Kurata M, Sanbe T, Sekiya I, Miyazaki A, Suzuki H.

Biochem Biophys Res Commun. 2016 Feb 12;470(3):657-662. doi: 10.1016/j.bbrc.2016.01.086. Epub 2016 Jan 18.

PMID:
26797283
39.
40.

Multiple coupled landscapes and non-adiabatic dynamics with applications to self-activating genes.

Chen C, Zhang K, Feng H, Sasai M, Wang J.

Phys Chem Chem Phys. 2015 Nov 21;17(43):29036-44. doi: 10.1039/c5cp04780c.

PMID:
26455835
41.

p62 Plays a Specific Role in Interferon-γ-Induced Presentation of a Toxoplasma Vacuolar Antigen.

Lee Y, Sasai M, Ma JS, Sakaguchi N, Ohshima J, Bando H, Saitoh T, Akira S, Yamamoto M.

Cell Rep. 2015 Oct 13;13(2):223-33. doi: 10.1016/j.celrep.2015.09.005. Epub 2015 Oct 1.

42.

RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.

Ohshima J, Sasai M, Liu J, Yamashita K, Ma JS, Lee Y, Bando H, Howard JC, Ebisu S, Hayashi M, Takeda K, Standley DM, Frickel EM, Yamamoto M.

Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):E4581-90. doi: 10.1073/pnas.1510031112. Epub 2015 Aug 3.

43.

VS-APPLE: A Virtual Screening Algorithm Using Promiscuous Protein-Ligand Complexes.

Okuno T, Kato K, Terada TP, Sasai M, Chikenji G.

J Chem Inf Model. 2015 Jun 22;55(6):1108-19. doi: 10.1021/acs.jcim.5b00134. Epub 2015 Jun 9.

PMID:
26057716
44.

Toll-like receptor 9 trafficking and signaling for type I interferons requires PIKfyve activity.

Hayashi K, Sasai M, Iwasaki A.

Int Immunol. 2015 Sep;27(9):435-45. doi: 10.1093/intimm/dxv021. Epub 2015 Apr 29.

45.

Liver abscessation and multiple septic pulmonary emboli associated with Lemierre's syndrome: a case report.

Takano Y, Fukuda K, Takayasu H, Shinmura K, Koizumi G, Sasai M, Nagayama Y, Kawamo M, Yasuda T, Watanabe K, Sasaki J, Hayashi M, Yamamura E, Maruoka N, Nagahama M, Takahashi H.

BMC Res Notes. 2015 Mar 3;8:65. doi: 10.1186/s13104-015-1028-9.

46.

Folding pathway of a multidomain protein depends on its topology of domain connectivity.

Inanami T, Terada TP, Sasai M.

Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):15969-74. doi: 10.1073/pnas.1406244111. Epub 2014 Sep 29.

47.

Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6.

Ma JS, Sasai M, Ohshima J, Lee Y, Bando H, Takeda K, Yamamoto M.

J Exp Med. 2014 Sep 22;211(10):2013-32. doi: 10.1084/jem.20131272. Epub 2014 Sep 15.

48.

Coupling of lever arm swing and biased Brownian motion in actomyosin.

Nie QM, Togashi A, Sasaki TN, Takano M, Sasai M, Terada TP.

PLoS Comput Biol. 2014 Apr 24;10(4):e1003552. doi: 10.1371/journal.pcbi.1003552. eCollection 2014 Apr.

49.

Role of mouse and human autophagy proteins in IFN-γ-induced cell-autonomous responses against Toxoplasma gondii.

Ohshima J, Lee Y, Sasai M, Saitoh T, Su Ma J, Kamiyama N, Matsuura Y, Pann-Ghill S, Hayashi M, Ebisu S, Takeda K, Akira S, Yamamoto M.

J Immunol. 2014 Apr 1;192(7):3328-35. doi: 10.4049/jimmunol.1302822. Epub 2014 Feb 21.

50.

Conformational flexibility of loops of myosin enhances the global bias in the actin-myosin interaction landscape.

Nie QM, Sasai M, Terada TP.

Phys Chem Chem Phys. 2014 Apr 14;16(14):6441-7. doi: 10.1039/c3cp54464h. Epub 2014 Feb 11.

PMID:
24513657

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