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Items: 1 to 50 of 177

1.

Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFRα in Adult Brain.

Đặng TC, Ishii Y, Nguyen V, Yamamoto S, Hamashima T, Okuno N, Nguyen QL, Sang Y, Ohkawa N, Saitoh Y, Shehata M, Takakura N, Fujimori T, Inokuchi K, Mori H, Andrae J, Betsholtz C, Sasahara M.

Cell Rep. 2019 Apr 23;27(4):1073-1089.e5. doi: 10.1016/j.celrep.2019.03.084.

2.

The Preoperative Prognostic Nutritional Index Predicts Short-Term and Long-Term Outcomes of Patients with Stage II/III Gastric Cancer: Analysis of a Multi-Institution Dataset.

Sasahara M, Kanda M, Ito S, Mochizuki Y, Teramoto H, Ishigure K, Murai T, Asada T, Ishiyama A, Matsushita H, Tanaka C, Kobayashi D, Fujiwara M, Murotani K, Kodera Y.

Dig Surg. 2019 Mar 6:1-10. doi: 10.1159/000497454. [Epub ahead of print]

PMID:
30840952
3.

Different PDGF Receptor Dimers Drive Distinct Migration Modes of the Mouse Skin Fibroblast.

Yamada K, Hamashima T, Ishii Y, Yamamoto S, Okuno N, Yoshida N, Yamada M, Huang TT, Shioda N, Tomihara K, Fujimori T, Mori H, Fukunaga K, Noguchi M, Sasahara M.

Cell Physiol Biochem. 2018;51(3):1461-1479. doi: 10.1159/000495594. Epub 2018 Nov 28.

4.

Partial depletion of CD206-positive M2-like macrophages induces proliferation of beige progenitors and enhances browning after cold stimulation.

Igarashi Y, Nawaz A, Kado T, Bilal M, Kuwano T, Yamamoto S, Sasahara M, Jiuxiang X, Inujima A, Koizumi K, Imura J, Shibahara N, Usui I, Fujisaka S, Tobe K.

Sci Rep. 2018 Oct 1;8(1):14567. doi: 10.1038/s41598-018-32803-6.

5.

Feasibility of anatomical feature points for the estimation of prostate locations in the Bayesian delineation frameworks for prostate cancer radiotherapy.

Ninomiya K, Arimura H, Sasahara M, Kai Y, Hirose TA, Ohga S.

Radiol Phys Technol. 2018 Dec;11(4):434-444. doi: 10.1007/s12194-018-0481-2. Epub 2018 Sep 28.

PMID:
30267211
6.

The Novel Pathogenesis of Retinopathy Mediated by Multiple RTK Signals is Uncovered in Newly Developed Mouse Model.

Kitahara H, Kajikawa S, Ishii Y, Yamamoto S, Hamashima T, Azuma E, Sato H, Matsushima T, Shibuya M, Shimada Y, Sasahara M.

EBioMedicine. 2018 May;31:190-201. doi: 10.1016/j.ebiom.2018.04.021. Epub 2018 Apr 25.

7.

PDGFR-β restores blood-brain barrier functions in a mouse model of focal cerebral ischemia.

Shen J, Xu G, Zhu R, Yuan J, Ishii Y, Hamashima T, Matsushima T, Yamamoto S, Takatsuru Y, Nabekura J, Sasahara M.

J Cereb Blood Flow Metab. 2018 Apr 9:271678X18769515. doi: 10.1177/0271678X18769515. [Epub ahead of print]

PMID:
29629621
8.

NK Cells Control Tumor-Promoting Function of Neutrophils in Mice.

Ogura K, Sato-Matsushita M, Yamamoto S, Hori T, Sasahara M, Iwakura Y, Saiki I, Tahara H, Hayakawa Y.

Cancer Immunol Res. 2018 Jan 23. doi: 10.1158/2326-6066.CIR-17-0204. [Epub ahead of print]

PMID:
29362222
9.

Serine racemase deletion attenuates neurodegeneration and microvascular damage in diabetic retinopathy.

Ozaki H, Inoue R, Matsushima T, Sasahara M, Hayashi A, Mori H.

PLoS One. 2018 Jan 5;13(1):e0190864. doi: 10.1371/journal.pone.0190864. eCollection 2018.

10.

Clinical predictors of pathological complete response to neoadjuvant chemotherapy in triple-negative breast cancer.

Nakashoji A, Matsui A, Nagayama A, Iwata Y, Sasahara M, Murata Y.

Oncol Lett. 2017 Oct;14(4):4135-4141. doi: 10.3892/ol.2017.6692. Epub 2017 Aug 1.

11.

Eplerenone prevented obesity-induced inflammasome activation and glucose intolerance.

Wada T, Ishikawa A, Watanabe E, Nakamura Y, Aruga Y, Hasegawa H, Onogi Y, Honda H, Nagai Y, Takatsu K, Ishii Y, Sasahara M, Koya D, Tsuneki H, Sasaoka T.

J Endocrinol. 2017 Dec;235(3):179-191. doi: 10.1530/JOE-17-0351. Epub 2017 Aug 30.

PMID:
28855315
12.

CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors.

Nawaz A, Aminuddin A, Kado T, Takikawa A, Yamamoto S, Tsuneyama K, Igarashi Y, Ikutani M, Nishida Y, Nagai Y, Takatsu K, Imura J, Sasahara M, Okazaki Y, Ueki K, Okamura T, Tokuyama K, Ando A, Matsumoto M, Mori H, Nakagawa T, Kobayashi N, Saeki K, Usui I, Fujisaka S, Tobe K.

Nat Commun. 2017 Aug 18;8(1):286. doi: 10.1038/s41467-017-00231-1.

13.

A subset of cerebrovascular pericytes originates from mature macrophages in the very early phase of vascular development in CNS.

Yamamoto S, Muramatsu M, Azuma E, Ikutani M, Nagai Y, Sagara H, Koo BN, Kita S, O'Donnell E, Osawa T, Takahashi H, Takano KI, Dohmoto M, Sugimori M, Usui I, Watanabe Y, Hatakeyama N, Iwamoto T, Komuro I, Takatsu K, Tobe K, Niida S, Matsuda N, Shibuya M, Sasahara M.

Sci Rep. 2017 Jun 20;7(1):3855. doi: 10.1038/s41598-017-03994-1.

14.

Pathogenetic significance and possibility as a therapeutic target of platelet derived growth factor.

Ishii Y, Hamashima T, Yamamoto S, Sasahara M.

Pathol Int. 2017 May;67(5):235-246. doi: 10.1111/pin.12530. Epub 2017 Apr 10. Review.

PMID:
28393435
15.

Overlapping memory trace indispensable for linking, but not recalling, individual memories.

Yokose J, Okubo-Suzuki R, Nomoto M, Ohkawa N, Nishizono H, Suzuki A, Matsuo M, Tsujimura S, Takahashi Y, Nagase M, Watabe AM, Sasahara M, Kato F, Inokuchi K.

Science. 2017 Jan 27;355(6323):398-403. doi: 10.1126/science.aal2690.

PMID:
28126819
16.

PDGFRβ Regulates Adipose Tissue Expansion and Glucose Metabolism via Vascular Remodeling in Diet-Induced Obesity.

Onogi Y, Wada T, Kamiya C, Inata K, Matsuzawa T, Inaba Y, Kimura K, Inoue H, Yamamoto S, Ishii Y, Koya D, Tsuneki H, Sasahara M, Sasaoka T.

Diabetes. 2017 Apr;66(4):1008-1021. doi: 10.2337/db16-0881. Epub 2017 Jan 25.

17.

Successful multimodal treatment of intraoral salivary duct carcinoma in a patient with multiple lymph node metastases: a case report.

Imaue S, Tomihara K, Hamashima T, Tomizawa G, Nomura K, Sasahara M, Noguchi M.

World J Surg Oncol. 2017 Jan 10;15(1):18. doi: 10.1186/s12957-016-1090-3.

18.

Endocytosis following dopamine D2 receptor activation is critical for neuronal activity and dendritic spine formation via Rabex-5/PDGFRβ signaling in striatopallidal medium spiny neurons.

Shioda N, Yabuki Y, Wang Y, Uchigashima M, Hikida T, Sasaoka T, Mori H, Watanabe M, Sasahara M, Fukunaga K.

Mol Psychiatry. 2017 Aug;22(8):1205-1222. doi: 10.1038/mp.2016.200. Epub 2016 Dec 6.

PMID:
27922607
19.

An intermediate vascular tumour between kaposiform hemangioendothelioma and tufted angioma with regression of the skin lesion.

Makino T, Ishida W, Hamashima T, Mizawa M, Sasahara M, Shimizu T.

Eur J Dermatol. 2017 Apr 1;27(2):175-176. doi: 10.1684/ejd.2016.2922. No abstract available.

PMID:
27882874
20.

Timed Inhibition of Orexin System by Suvorexant Improved Sleep and Glucose Metabolism in Type 2 Diabetic db/db Mice.

Tsuneki H, Kon K, Ito H, Yamazaki M, Takahara S, Toyooka N, Ishii Y, Sasahara M, Wada T, Yanagisawa M, Sakurai T, Sasaoka T.

Endocrinology. 2016 Nov;157(11):4146-4157. Epub 2016 Sep 15.

PMID:
27631554
21.

Significance of Extracellular Vesicles: Pathobiological Roles in Disease.

Yamamoto S, Azuma E, Muramatsu M, Hamashima T, Ishii Y, Sasahara M.

Cell Struct Funct. 2016 Nov 25;41(2):137-143. Epub 2016 Sep 29. Review.

22.

HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance.

Takikawa A, Mahmood A, Nawaz A, Kado T, Okabe K, Yamamoto S, Aminuddin A, Senda S, Tsuneyama K, Ikutani M, Watanabe Y, Igarashi Y, Nagai Y, Takatsu K, Koizumi K, Imura J, Goda N, Sasahara M, Matsumoto M, Saeki K, Nakagawa T, Fujisaka S, Usui I, Tobe K.

Diabetes. 2016 Dec;65(12):3649-3659. Epub 2016 Sep 13.

23.

Pericyte-fibroblast transition promotes tumor growth and metastasis.

Hosaka K, Yang Y, Seki T, Fischer C, Dubey O, Fredlund E, Hartman J, Religa P, Morikawa H, Ishii Y, Sasahara M, Larsson O, Cossu G, Cao R, Lim S, Cao Y.

Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5618-27. doi: 10.1073/pnas.1608384113. Epub 2016 Sep 7.

24.

Mobilization of Pluripotent Multilineage-Differentiating Stress-Enduring Cells in Ischemic Stroke.

Hori E, Hayakawa Y, Hayashi T, Hori S, Okamoto S, Shibata T, Kubo M, Horie Y, Sasahara M, Kuroda S.

J Stroke Cerebrovasc Dis. 2016 Jun;25(6):1473-81. doi: 10.1016/j.jstrokecerebrovasdis.2015.12.033. Epub 2016 Mar 24.

PMID:
27019988
25.

Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice.

Watanabe Y, Nagai Y, Honda H, Okamoto N, Yamamoto S, Hamashima T, Ishii Y, Tanaka M, Suganami T, Sasahara M, Miyake K, Takatsu K.

Sci Rep. 2016 Mar 15;6:23097. doi: 10.1038/srep23097.

26.

Glioma-Derived Platelet-Derived Growth Factor-BB Recruits Oligodendrocyte Progenitor Cells via Platelet-Derived Growth Factor Receptor-α and Remodels Cancer Stroma.

Zheng Y, Yamamoto S, Ishii Y, Sang Y, Hamashima T, Van De N, Nishizono H, Inoue R, Mori H, Sasahara M.

Am J Pathol. 2016 May;186(5):1081-91. doi: 10.1016/j.ajpath.2015.12.020. Epub 2016 Mar 3.

PMID:
26945107
27.

PDGFRα plays a crucial role in connective tissue remodeling.

Horikawa S, Ishii Y, Hamashima T, Yamamoto S, Mori H, Fujimori T, Shen J, Inoue R, Nishizono H, Itoh H, Majima M, Abraham D, Miyawaki T, Sasahara M.

Sci Rep. 2015 Dec 7;5:17948. doi: 10.1038/srep17948.

28.

PDGFR-β Plays a Key Role in the Ectopic Migration of Neuroblasts in Cerebral Stroke.

Sato H, Ishii Y, Yamamoto S, Azuma E, Takahashi Y, Hamashima T, Umezawa A, Mori H, Kuroda S, Endo S, Sasahara M.

Stem Cells. 2016 Mar;34(3):685-98. doi: 10.1002/stem.2212. Epub 2015 Oct 4.

29.

Teneligliptin improves metabolic abnormalities in a mouse model of postmenopausal obesity.

Sameshima A, Wada T, Ito T, Kashimura A, Sawakawa K, Yonezawa R, Tsuneki H, Ishii Y, Sasahara M, Saito S, Sasaoka T.

J Endocrinol. 2015 Oct;227(1):25-36. doi: 10.1530/JOE-15-0239. Epub 2015 Aug 11.

PMID:
26264980
30.

Metabolism of dextran sulfate sodium by intestinal bacteria in rat cecum is related to induction of colitis.

Akao T, Oyanagi Y, Shiotsuki S, Ishii Y, Sasahara M.

Biol Pharm Bull. 2015;38(4):566-70. doi: 10.1248/bpb.b14-00708.

31.

Relationships among parvalbumin-immunoreactive neuron density, phase-locked gamma oscillations, and autistic/schizophrenic symptoms in PDGFR-β knock-out and control mice.

Nakamura T, Matsumoto J, Takamura Y, Ishii Y, Sasahara M, Ono T, Nishijo H.

PLoS One. 2015 Mar 24;10(3):e0119258. doi: 10.1371/journal.pone.0119258. eCollection 2015.

32.

Inflammation-induced endothelial cell-derived extracellular vesicles modulate the cellular status of pericytes.

Yamamoto S, Niida S, Azuma E, Yanagibashi T, Muramatsu M, Huang TT, Sagara H, Higaki S, Ikutani M, Nagai Y, Takatsu K, Miyazaki K, Hamashima T, Mori H, Matsuda N, Ishii Y, Sasahara M.

Sci Rep. 2015 Feb 17;5:8505. doi: 10.1038/srep08505.

33.

Extramammary Paget's disease occurring in the context of Cowden syndrome: true association or mere coincidence?

Matsui K, Makino T, Mizawa M, Hamashima T, Hanakawa H, Hatta N, Sasahara M, Shimizu T.

Eur J Dermatol. 2015 Jan-Feb;25(1):89-91. doi: 10.1684/ejd.2014.2475. No abstract available.

PMID:
25500562
34.

Sarcomatoid salivary duct carcinoma of the palate: a rare case report.

Tomihara K, Hamashima T, Nagao T, Nakamori K, Sasahara M, Noguchi M.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Jan;119(1):e27-32. doi: 10.1016/j.oooo.2014.08.007. Epub 2014 Aug 19.

PMID:
25443810
35.

Nicotine suppresses acute colitis and colonic tumorigenesis associated with chronic colitis in mice.

Hayashi S, Hamada T, Zaidi SF, Oshiro M, Lee J, Yamamoto T, Ishii Y, Sasahara M, Kadowaki M.

Am J Physiol Gastrointest Liver Physiol. 2014 Nov 15;307(10):G968-78. doi: 10.1152/ajpgi.00346.2013. Epub 2014 Sep 25.

36.

Immunohistological examination of a skin lesion in a Japanese case with hand, foot and mouth disease caused by coxsackie-virus A6.

Seki Y, Makino T, Mizawa M, Hamashima T, Sasahara M, Shimizu T.

Eur J Dermatol. 2014 Jul-Aug;24(4):506-7. doi: 10.1684/ejd.2014.2379. No abstract available.

PMID:
25120139
37.

Overexpression of androgen receptor and forkhead-box A1 protein in apocrine breast carcinoma.

Sasahara M, Matsui A, Ichimura Y, Hirakata Y, Murata Y, Marui E.

Anticancer Res. 2014 Mar;34(3):1261-7.

PMID:
24596370
38.

PDGF suppresses oxidative stress induced Ca2+ overload and calpain activation in neurons.

Zheng LS, Ishii Y, Zhao QL, Kondo T, Sasahara M.

Oxid Med Cell Longev. 2013;2013:367206. doi: 10.1155/2013/367206. Epub 2013 Dec 24.

39.

Changes in Otx2 and parvalbumin immunoreactivity in the superior colliculus in the platelet-derived growth factor receptor-β knockout mice.

Zhao J, Urakawa S, Matsumoto J, Li R, Ishii Y, Sasahara M, Peng Y, Ono T, Nishijo H.

Biomed Res Int. 2013;2013:848265. doi: 10.1155/2013/848265. Epub 2013 Nov 11.

40.

Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP-1c Tg mice fed high-fat and high-fructose diet.

Wada T, Miyashita Y, Sasaki M, Aruga Y, Nakamura Y, Ishii Y, Sasahara M, Kanasaki K, Kitada M, Koya D, Shimano H, Tsuneki H, Sasaoka T.

Am J Physiol Endocrinol Metab. 2013 Dec 1;305(11):E1415-25. doi: 10.1152/ajpendo.00419.2013. Epub 2013 Oct 15.

41.

The roles of PDGF in development and during neurogenesis in the normal and diseased nervous system.

Funa K, Sasahara M.

J Neuroimmune Pharmacol. 2014 Mar;9(2):168-81. doi: 10.1007/s11481-013-9479-z. Epub 2013 Jun 15. Review.

42.

Cilostazol ameliorates systemic insulin resistance in diabetic db/db mice by suppressing chronic inflammation in adipose tissue via modulation of both adipocyte and macrophage functions.

Wada T, Onogi Y, Kimura Y, Nakano T, Fusanobori H, Ishii Y, Sasahara M, Tsuneki H, Sasaoka T.

Eur J Pharmacol. 2013 May 5;707(1-3):120-9. doi: 10.1016/j.ejphar.2013.03.016. Epub 2013 Mar 22.

PMID:
23528355
43.

Functional analysis of platelet-derived growth factor receptor-β in neural stem/progenitor cells.

Xu G, Shen J, Ishii Y, Fukuchi M, Dang TC, Zheng Y, Hamashima T, Fujimori T, Tsuda M, Funa K, Sasahara M.

Neuroscience. 2013 May 15;238:195-208. doi: 10.1016/j.neuroscience.2013.02.021. Epub 2013 Feb 20.

PMID:
23454370
44.

SH2-containing inositol 5'-phosphatase 2 selectively impairs hypothalamic insulin signalling and regulation of food intake in mice.

Ichihara Y, Wada T, Soeda Y, Ishii Y, Sasahara M, Tsuneki H, Sasaoka T.

J Neuroendocrinol. 2013 Apr;25(4):372-82. doi: 10.1111/jne.12014.

PMID:
23286299
45.

Cancer stem cells: the 'heartbeat' of gastric cancer.

Xu G, Shen J, Ou Yang X, Sasahara M, Su X.

J Gastroenterol. 2013 Jul;48(7):781-97. doi: 10.1007/s00535-012-0712-y. Epub 2012 Nov 27. Review.

PMID:
23184096
46.

Sirtuin 1 activator SRT1720 suppresses inflammation in an ovalbumin-induced mouse model of asthma.

Ichikawa T, Hayashi R, Suzuki K, Imanishi S, Kambara K, Okazawa S, Inomata M, Yamada T, Yamazaki Y, Koshimizu Y, Miwa T, Matsui S, Usui I, Urakaze M, Matsuya Y, Sasahara M, Tobe K.

Respirology. 2013 Feb;18(2):332-9. doi: 10.1111/j.1440-1843.2012.02284.x.

PMID:
23062010
47.

Miliary brain metastasis presenting with calcification in a patient with lung cancer: a case report.

Inomata M, Hayashi R, Kambara K, Okazawa S, Imanishi S, Ichikawa T, Suzuki K, Yamada T, Miwa T, Kashii T, Matsui S, Tobe K, Sasahara M.

J Med Case Rep. 2012 Sep 4;6:279. doi: 10.1186/1752-1947-6-279.

48.

Central versus peripheral impact of estradiol on the impaired glucose metabolism in ovariectomized mice on a high-fat diet.

Yonezawa R, Wada T, Matsumoto N, Morita M, Sawakawa K, Ishii Y, Sasahara M, Tsuneki H, Saito S, Sasaoka T.

Am J Physiol Endocrinol Metab. 2012 Aug 15;303(4):E445-56. doi: 10.1152/ajpendo.00638.2011. Epub 2012 May 1.

49.

PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells.

Xue Y, Lim S, Yang Y, Wang Z, Jensen LD, Hedlund EM, Andersson P, Sasahara M, Larsson O, Galter D, Cao R, Hosaka K, Cao Y.

Nat Med. 2011 Dec 4;18(1):100-10. doi: 10.1038/nm.2575.

PMID:
22138754
50.

Platelet-derived growth factor and renal disease.

Nakagawa T, Inoue H, Sasahara M.

Curr Opin Nephrol Hypertens. 2012 Jan;21(1):80-5. doi: 10.1097/MNH.0b013e32834db4d3. Review.

PMID:
22123208

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