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Items: 1 to 50 of 197

1.

Anti-human Interleukin(IL)-4 Clone 8D4-8 Cross-Reacts With Myosin-9 Associated With Apoptotic Cells and Should Not Be Used for Flow Cytometry Applications Querying IL-4 Expression.

Harms RZ, Borengasser K, Kumar V, Sarvetnick N.

Front Cell Dev Biol. 2019 Apr 9;7:46. doi: 10.3389/fcell.2019.00046. eCollection 2019.

2.

Coordinated Induction of Antimicrobial Response Factors in Systemic Lupus Erythematosus.

Ayyappan P, Harms RZ, Buckner JH, Sarvetnick NE.

Front Immunol. 2019 Apr 4;10:658. doi: 10.3389/fimmu.2019.00658. eCollection 2019.

3.

Current understanding of the role of gut dysbiosis in type 1 diabetes.

Abdellatif AM, Sarvetnick NE.

J Diabetes. 2019 Aug;11(8):632-644. doi: 10.1111/1753-0407.12915. Epub 2019 Apr 22. Review.

PMID:
30864231
4.

Abnormal T Cell Frequencies, Including Cytomegalovirus-Associated Expansions, Distinguish Seroconverted Subjects at Risk for Type 1 Diabetes.

Harms RZ, Lorenzo-Arteaga KM, Ostlund KR, Smith VB, Smith LM, Gottlieb P, Sarvetnick N.

Front Immunol. 2018 Oct 22;9:2332. doi: 10.3389/fimmu.2018.02332. eCollection 2018.

5.

Interleukin (IL)-18 Binding Protein Deficiency Disrupts Natural Killer Cell Maturation and Diminishes Circulating IL-18.

Harms RZ, Creer AJ, Lorenzo-Arteaga KM, Ostlund KR, Sarvetnick NE.

Front Immunol. 2017 Aug 28;8:1020. doi: 10.3389/fimmu.2017.01020. eCollection 2017.

6.

Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass.

George NM, Boerner BP, Mir SU, Guinn Z, Sarvetnick NE.

Mol Endocrinol. 2015 Nov;29(11):1594-607. doi: 10.1210/me.2014-1375. Epub 2015 Sep 17.

7.

WS6 induces both alpha and beta cell proliferation without affecting differentiation or viability.

Boerner BP, George NM, Mir SU, Sarvetnick NE.

Endocr J. 2015;62(4):379-86. doi: 10.1507/endocrj.EJ14-0449. Epub 2015 Mar 11.

8.

Altered CD161 bright CD8+ mucosal associated invariant T (MAIT)-like cell dynamics and increased differentiation states among juvenile type 1 diabetics.

Harms RZ, Lorenzo KM, Corley KP, Cabrera MS, Sarvetnick NE.

PLoS One. 2015 Jan 27;10(1):e0117335. doi: 10.1371/journal.pone.0117335. eCollection 2015.

9.

Increased expression of IL-18 in the serum and islets of type 1 diabetics.

Harms RZ, Yarde DN, Guinn Z, Lorenzo-Arteaga KM, Corley KP, Cabrera MS, Sarvetnick NE.

Mol Immunol. 2015 Apr;64(2):306-312. doi: 10.1016/j.molimm.2014.12.012. Epub 2015 Jan 7.

10.

Inhibition of autophagic turnover in β-cells by fatty acids and glucose leads to apoptotic cell death.

Mir SU, George NM, Zahoor L, Harms R, Guinn Z, Sarvetnick NE.

J Biol Chem. 2015 Mar 6;290(10):6071-85. doi: 10.1074/jbc.M114.605345. Epub 2014 Dec 29.

11.

CD28⁻ CD8⁺ T cells are significantly reduced and correlate with disease duration in juveniles with type 1 diabetes.

Yarde DN, Lorenzo-Arteaga K, Corley KP, Cabrera M, Sarvetnick NE.

Hum Immunol. 2014 Oct;75(10):1069-74. doi: 10.1016/j.humimm.2014.09.007. Epub 2014 Sep 19.

12.

TLR signaling controls lethal encephalitis in WNV-infected brain.

Sabouri AH, Marcondes MC, Flynn C, Berger M, Xiao N, Fox HS, Sarvetnick NE.

Brain Res. 2014 Jul 29;1574:84-95. doi: 10.1016/j.brainres.2014.05.049. Epub 2014 Jun 11.

13.

TGF-β superfamily member Nodal stimulates human β-cell proliferation while maintaining cellular viability.

Boerner BP, George NM, Targy NM, Sarvetnick NE.

Endocrinology. 2013 Nov;154(11):4099-112. doi: 10.1210/en.2013-1197. Epub 2013 Aug 22.

14.

Altered RECQ Helicase Expression in Sporadic Primary Colorectal Cancers.

Lao VV, Welcsh P, Luo Y, Carter KT, Dzieciatkowski S, Dintzis S, Meza J, Sarvetnick NE, Monnat RJ Jr, Loeb LA, Grady WM.

Transl Oncol. 2013 Aug 1;6(4):458-69. Print 2013 Aug.

15.

Methamphetamine administration targets multiple immune subsets and induces phenotypic alterations suggestive of immunosuppression.

Harms R, Morsey B, Boyer CW, Fox HS, Sarvetnick N.

PLoS One. 2012;7(12):e49897. doi: 10.1371/journal.pone.0049897. Epub 2012 Dec 5.

16.

Hippo signaling regulates pancreas development through inactivation of Yap.

George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE.

Mol Cell Biol. 2012 Dec;32(24):5116-28. doi: 10.1128/MCB.01034-12. Epub 2012 Oct 15.

17.

Type 1 diabetes: role of intestinal microbiome in humans and mice.

Boerner BP, Sarvetnick NE.

Ann N Y Acad Sci. 2011 Dec;1243:103-18. doi: 10.1111/j.1749-6632.2011.06340.x. Review.

PMID:
22211896
18.

Differential IL-21 signaling in APCs leads to disparate Th17 differentiation in diabetes-susceptible NOD and diabetes-resistant NOD.Idd3 mice.

Liu SM, Lee DH, Sullivan JM, Chung D, Jäger A, Shum BO, Sarvetnick NE, Anderson AC, Kuchroo VK.

J Clin Invest. 2011 Nov;121(11):4303-10. doi: 10.1172/JCI46187. Epub 2011 Oct 24.

19.

IL-18 is required for self-reactive T cell expansion in NOD mice.

Marleau AM, Sarvetnick NE.

J Autoimmun. 2011 May;36(3-4):263-77. doi: 10.1016/j.jaut.2011.02.005. Epub 2011 Mar 16.

20.

The incidence of type-1 diabetes in NOD mice is modulated by restricted flora not germ-free conditions.

King C, Sarvetnick N.

PLoS One. 2011 Feb 25;6(2):e17049. doi: 10.1371/journal.pone.0017049.

21.

Beta-cell specific expression of suppressor of cytokine signaling-1 (SOCS-1) delays islet allograft rejection by down-regulating Interferon Regulatory Factor-1 (IRF-1) signaling.

Solomon M, Flodström-Tullberg M, Sarvetnick N.

Transpl Immunol. 2011 Apr 15;24(3):181-8. doi: 10.1016/j.trim.2010.11.007. Epub 2010 Dec 1.

PMID:
21130166
22.

Epithelial progenitor 1, a novel factor associated with epithelial cell growth and differentiation.

Kritzik MR, Lago CU, Kayali AG, Arnaud-Dabernat S, Liu G, Zhang YQ, Hua H, Fox HS, Sarvetnick NE.

Endocrine. 2010 Apr;37(2):312-21. doi: 10.1007/s12020-009-9297-5. Epub 2010 Jan 9.

23.

CCR2 and CCR5 chemokine receptors differentially influence the development of autoimmune diabetes in the NOD mouse.

Solomon M, Balasa B, Sarvetnick N.

Autoimmunity. 2010 Mar;43(2):156-63. doi: 10.3109/08916930903246464.

PMID:
19824873
24.

Lymphocyte proliferation in immune-mediated diseases.

Datta S, Sarvetnick N.

Trends Immunol. 2009 Sep;30(9):430-8. doi: 10.1016/j.it.2009.06.002. Epub 2009 Aug 19. Review.

PMID:
19699149
25.

Upregulation of activin signaling in experimental colitis.

Zhang YQ, Resta S, Jung B, Barrett KE, Sarvetnick N.

Am J Physiol Gastrointest Liver Physiol. 2009 Oct;297(4):G768-80. doi: 10.1152/ajpgi.90631.2008. Epub 2009 Jul 30.

26.

Lack of beta-catenin in early life induces abnormal glucose homeostasis in mice.

Dabernat S, Secrest P, Peuchant E, Moreau-Gaudry F, Dubus P, Sarvetnick N.

Diabetologia. 2009 Aug;52(8):1608-17. doi: 10.1007/s00125-009-1411-y. Epub 2009 Jun 10.

27.

Altered availability of PD-1/PD ligands is associated with the failure to control autoimmunity in NOD mice.

Yadav D, Hill N, Yagita H, Azuma M, Sarvetnick N.

Cell Immunol. 2009;258(2):161-71. doi: 10.1016/j.cellimm.2009.04.006. Epub 2009 May 6.

PMID:
19497561
28.

IL-21 limits peripheral lymphocyte numbers through T cell homeostatic mechanisms.

Datta S, Sarvetnick NE.

PLoS One. 2008 Sep 5;3(9):e3118. doi: 10.1371/journal.pone.0003118.

29.

Nodal and lefty signaling regulates the growth of pancreatic cells.

Zhang YQ, Sterling L, Stotland A, Hua H, Kritzik M, Sarvetnick N.

Dev Dyn. 2008 May;237(5):1255-67. doi: 10.1002/dvdy.21527.

30.

Expression of Id1 in adult, regenerating and developing pancreas.

Hua H, Sarvetnick N.

Endocrine. 2007 Dec;32(3):280-6. doi: 10.1007/s12020-008-9036-3. Epub 2008 Mar 6.

PMID:
18322823
31.

ID2 promotes the expansion and survival of growth-arrested pancreatic beta cells.

Hua H, Sarvetnick N.

Endocrine. 2007 Dec;32(3):329-37. doi: 10.1007/s12020-008-9039-0. Epub 2008 Mar 6.

PMID:
18322822
32.

FGFR3 contributes to intestinal crypt cell growth arrest.

Arnaud-Dabernat S, Yadav D, Sarvetnick N.

J Cell Physiol. 2008 Jul;216(1):261-8. doi: 10.1002/jcp.21401.

PMID:
18286540
33.

Costimulation and pancreatic autoimmunity: the PD-1/PD-L conundrum.

Yadav D, Sarvetnick N.

Rev Diabet Stud. 2006 Spring;3(1):6-10. Epub 2006 May 10.

34.

B7-2 regulates survival, phenotype, and function of APCs.

Yadav D, Sarvetnick N.

J Immunol. 2007 May 15;178(10):6236-41.

35.

Tyrosine kinase receptors are crucial for normal β-cell development and function.

Arnaud-Dabernat S, Sarvetnick N.

Expert Rev Endocrinol Metab. 2007 Mar;2(2):175-183. doi: 10.1586/17446651.2.2.175.

PMID:
30754179
36.

The target tissue in autoimmunity--an influential niche.

Hill NJ, Hultcrantz M, Sarvetnick N, Flodström-Tullberg M.

Eur J Immunol. 2007 Mar;37(3):589-97. Review.

37.

B7-1 mediated costimulation regulates pancreatic autoimmunity.

Yadav D, Fine C, Azuma M, Sarvetnick N.

Mol Immunol. 2007 Apr;44(10):2616-24. Epub 2007 Feb 7.

38.

Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes.

Hill NJ, Stotland A, Solomon M, Secrest P, Getzoff E, Sarvetnick N.

Biol Direct. 2007 Jan 25;2:5.

39.

Immunomodulation of the anti-islet CD8 T cell response by B7-2.

Yadav D, Sarvetnick N.

J Clin Immunol. 2007 Mar;27(2):221-6. Epub 2007 Jan 23.

PMID:
17243007
40.

Transforming growth factor-beta inhibits coxsackievirus-mediated autoimmune myocarditis.

Horwitz MS, Knudsen M, Ilic A, Fine C, Sarvetnick N.

Viral Immunol. 2006 Winter;19(4):722-33.

PMID:
17201667
41.

FGFR3 is a negative regulator of the expansion of pancreatic epithelial cells.

Arnaud-Dabernat S, Kritzik M, Kayali AG, Zhang YQ, Liu G, Ungles C, Sarvetnick N.

Diabetes. 2007 Jan;56(1):96-106.

42.

PYY in the expanding pancreatic epithelium.

Liu G, Arnaud-Dabernat S, Kritzik MR, Kayali AG, Zhang YQ, Sarvetnick N.

Endocrine. 2006 Aug;30(1):103-12.

PMID:
17185798
43.

Distinct regulation of autoreactive CD4 T cell expansion by interleukin-4 under conditions of lymphopenia.

Hill NJ, Stotland AB, Sarvetnick NE.

J Leukoc Biol. 2007 Mar;81(3):757-65. Epub 2006 Dec 12.

PMID:
17164429
44.

BMP4 regulates pancreatic progenitor cell expansion through Id2.

Hua H, Zhang YQ, Dabernat S, Kritzik M, Dietz D, Sterling L, Sarvetnick N.

J Biol Chem. 2006 May 12;281(19):13574-80. Epub 2006 Mar 17.

45.

STAT4/6-dependent differential regulation of chemokine receptors.

Kim SH, Gunst KV, Sarvetnick N.

Clin Immunol. 2006 Feb-Mar;118(2-3):250-7. Epub 2006 Jan 18.

PMID:
16413227
46.

CD8+ T cell tolerance in nonobese diabetic mice is restored by insulin-dependent diabetes resistance alleles.

Martinez X, Kreuwel HT, Redmond WL, Trenney R, Hunter K, Rosen H, Sarvetnick N, Wicker LS, Sherman LA.

J Immunol. 2005 Aug 1;175(3):1677-85.

47.

Induction of antigen specific peripheral humoral tolerance to cardiac myosin does not prevent CB3-mediated autoimmune myocarditis.

Horwitz MS, Ilic A, Fine C, Sarvetnick N.

J Autoimmun. 2005 Sep;25(2):102-11. Epub 2005 Jul 11.

PMID:
16011890
48.

Identification and expansion of pancreatic stem/progenitor cells.

Zhang YQ, Kritzik M, Sarvetnick N.

J Cell Mol Med. 2005 Apr-Jun;9(2):331-44. Review.

49.

T cell homeostasis in tolerance and immunity.

Marleau AM, Sarvetnick N.

J Leukoc Biol. 2005 Sep;78(3):575-84. Epub 2005 May 13. Review.

PMID:
15894586
50.

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