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Items: 1 to 50 of 260

1.

Influence of Crohn's disease related polymorphisms in innate immune function on ileal microbiome.

Li E, Zhang Y, Tian X, Wang X, Gathungu G, Wolber A, Shiekh SS, Sartor RB, Davidson NO, Ciorba MA, Zhu W, Nelson LM, Robertson CE, Frank DN.

PLoS One. 2019 Feb 28;14(2):e0213108. doi: 10.1371/journal.pone.0213108. eCollection 2019.

2.

Murine Adherent and Invasive E. coli Induces Chronic Inflammation and Immune Responses in the Small and Large Intestines of Monoassociated IL-10-/- Mice Independent of Long Polar Fimbriae Adhesin A.

Schmitz JM, Tonkonogy SL, Dogan B, Leblond A, Whitehead KJ, Kim SC, Simpson KW, Sartor RB.

Inflamm Bowel Dis. 2018 Dec 21. doi: 10.1093/ibd/izy386. [Epub ahead of print]

PMID:
30576451
3.

Intestinal bacterial biofilms modulate mucosal immune responses.

Ellermann M, Sartor RB.

J Immunol Sci. 2018;2(2):13-18.

4.

Environmental Factors Modify the Severity of Acute DSS Colitis in Caspase-11-Deficient Mice.

Fan TJ, Tchaptchet SY, Arsene D, Mishima Y, Liu B, Sartor RB, Carroll IM, Miao EA, Fodor AA, Hansen JJ.

Inflamm Bowel Dis. 2018 Oct 12;24(11):2394-2403. doi: 10.1093/ibd/izy244.

PMID:
30312415
5.

Opioid Toxicity in Inflammatory Bowel Disease Patients Likely Includes Direct Enterocyte Effects That Exacerbate Disease.

Goldsmith JR, Sartor RB.

Clin Gastroenterol Hepatol. 2018 Oct;16(10):1679-1680. doi: 10.1016/j.cgh.2018.05.017. No abstract available.

PMID:
30243353
6.

The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis.

Truax AD, Chen L, Tam JW, Cheng N, Guo H, Koblansky AA, Chou WC, Wilson JE, Brickey WJ, Petrucelli A, Liu R, Cooper DE, Koenigsknecht MJ, Young VB, Netea MG, Stienstra R, Sartor RB, Montgomery SA, Coleman RA, Ting JP.

Cell Host Microbe. 2018 Sep 12;24(3):364-378.e6. doi: 10.1016/j.chom.2018.08.009.

PMID:
30212649
7.

Act1 is a negative regulator in T and B cells via direct inhibition of STAT3.

Zhang CJ, Wang C, Jiang M, Gu C, Xiao J, Chen X, Martin BN, Tang F, Yamamoto E, Xian Y, Wang H, Li F, Sartor RB, Smith H, Husni ME, Shi FD, Gao J, Carman J, Dongre A, McKarns SC, Coppieters K, Jørgensen TN, Leonard WJ, Li X.

Nat Commun. 2018 Jul 16;9(1):2745. doi: 10.1038/s41467-018-04974-3.

8.

Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome.

Jacob N, Jacobs JP, Kumagai K, Ha CWY, Kanazawa Y, Lagishetty V, Altmayer K, Hamill AM, Von Arx A, Sartor RB, Devkota S, Braun J, Michelsen KS, Targan SR, Shih DQ.

Mucosal Immunol. 2018 Sep;11(5):1466-1476. doi: 10.1038/s41385-018-0055-y. Epub 2018 Jul 9.

9.

Predicting Risk of Postoperative Disease Recurrence in Crohn's Disease: Patients With Indolent Crohn's Disease Have Distinct Whole Transcriptome Profiles at the Time of First Surgery.

Cushing KC, Mclean R, McDonald KG, Gustafsson JK, Knoop KA, Kulkarni DH, Sartor RB, Newberry RD.

Inflamm Bowel Dis. 2019 Jan 1;25(1):180-193. doi: 10.1093/ibd/izy228.

PMID:
29982468
10.

Osteoarthritis induced by destabilization of the medial meniscus is reduced in germ-free mice.

Ulici V, Kelley KL, Azcarate-Peril MA, Cleveland RJ, Sartor RB, Schwartz TA, Loeser RF.

Osteoarthritis Cartilage. 2018 Aug;26(8):1098-1109. doi: 10.1016/j.joca.2018.05.016. Epub 2018 May 30.

PMID:
29857156
11.

Fecal and Mucosa-Associated Intestinal Microbiota in Patients with Diarrhea-Predominant Irritable Bowel Syndrome.

Maharshak N, Ringel Y, Katibian D, Lundqvist A, Sartor RB, Carroll IM, Ringel-Kulka T.

Dig Dis Sci. 2018 Jul;63(7):1890-1899. doi: 10.1007/s10620-018-5086-4. Epub 2018 May 17.

PMID:
29777439
12.

Dietary and Microbial Oxazoles Induce Intestinal Inflammation by Modulating Aryl Hydrocarbon Receptor Responses.

Iyer SS, Gensollen T, Gandhi A, Oh SF, Neves JF, Collin F, Lavin R, Serra C, Glickman J, de Silva PSA, Sartor RB, Besra G, Hauser R, Maxwell A, Llebaria A, Blumberg RS.

Cell. 2018 May 17;173(5):1123-1134.e11. doi: 10.1016/j.cell.2018.04.037.

PMID:
29775592
13.

A screen of Crohn's disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells.

Chang YL, Rossetti M, Vlamakis H, Casero D, Sunga G, Harre N, Miller S, Humphries R, Stappenbeck T, Simpson KW, Sartor RB, Wu G, Lewis J, Bushman F, McGovern DPB, Salzman N, Borneman J, Xavier R, Huttenhower C, Braun J.

Mucosal Immunol. 2019 Mar;12(2):457-467. doi: 10.1038/s41385-018-0022-7. Epub 2018 Apr 25.

14.

The Pancreatic Cancer Microbiome Promotes Oncogenesis by Induction of Innate and Adaptive Immune Suppression.

Pushalkar S, Hundeyin M, Daley D, Zambirinis CP, Kurz E, Mishra A, Mohan N, Aykut B, Usyk M, Torres LE, Werba G, Zhang K, Guo Y, Li Q, Akkad N, Lall S, Wadowski B, Gutierrez J, Kochen Rossi JA, Herzog JW, Diskin B, Torres-Hernandez A, Leinwand J, Wang W, Taunk PS, Savadkar S, Janal M, Saxena A, Li X, Cohen D, Sartor RB, Saxena D, Miller G.

Cancer Discov. 2018 Apr;8(4):403-416. doi: 10.1158/2159-8290.CD-17-1134. Epub 2018 Mar 22.

PMID:
29567829
15.

Gut microbial composition can differentially regulate bile acid synthesis in humanized mice.

Kang DJ, Hylemon PB, Gillevet PM, Sartor RB, Betrapally NS, Kakiyama G, Sikaroodi M, Takei H, Nittono H, Zhou H, Pandak WM, Yang J, Jiao C, Li X, Lippman HR, Heuman DM, Bajaj JS.

Hepatol Commun. 2017 Feb 27;1(1):61-70. doi: 10.1002/hep4.1020. eCollection 2017 Feb.

16.

Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice.

Rogala AR, Schoenborn AA, Fee BE, Cantillana VA, Joyce MJ, Gharaibeh RZ, Roy S, Fodor AA, Sartor RB, Taylor GA, Gulati AS.

Dis Model Mech. 2018 Feb 7;11(2). pii: dmm031070. doi: 10.1242/dmm.031070.

17.

Intergenerational transfer of antibiotic-perturbed microbiota enhances colitis in susceptible mice.

Schulfer AF, Battaglia T, Alvarez Y, Bijnens L, Ruiz VE, Ho M, Robinson S, Ward T, Cox LM, Rogers AB, Knights D, Sartor RB, Blaser MJ.

Nat Microbiol. 2018 Feb;3(2):234-242. doi: 10.1038/s41564-017-0075-5. Epub 2017 Nov 27.

18.

Guiding longitudinal sampling in IBD cohorts.

Vázquez-Baeza Y, Gonzalez A, Xu ZZ, Washburne A, Herfarth HH, Sartor RB, Knight R.

Gut. 2018 Sep;67(9):1743-1745. doi: 10.1136/gutjnl-2017-315352. Epub 2017 Oct 21. No abstract available.

19.

Corrigendum: NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth.

Chen L, Wilson JE, Koenigsknecht MJ, Chou WC, Montgomery SA, Truax AD, Brickey WJ, Packey CD, Maharshak N, Matsushima GK, Plevy SE, Young VB, Sartor RB, Ting JP.

Nat Immunol. 2017 Oct 18;18(11):1270. doi: 10.1038/ni1117-1270b.

PMID:
29044233
20.

Erratum: NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth.

Chen L, Wilson JE, Koenigsknecht MJ, Chou WC, Montgomery SA, Truax AD, Brickey WJ, Packey CD, Maharshak N, Matsushima GK, Plevy SE, Young VB, Sartor RB, Ting JP.

Nat Immunol. 2017 Jul 19;18(8):951. doi: 10.1038/ni0817-951e. No abstract available.

PMID:
28722719
21.

Dietary Salt Exacerbates Experimental Colitis.

Tubbs AL, Liu B, Rogers TD, Sartor RB, Miao EA.

J Immunol. 2017 Aug 1;199(3):1051-1059. doi: 10.4049/jimmunol.1700356. Epub 2017 Jun 21.

22.

MDR1 deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation.

Ho GT, Aird RE, Liu B, Boyapati RK, Kennedy NA, Dorward DA, Noble CL, Shimizu T, Carter RN, Chew ETS, Morton NM, Rossi AG, Sartor RB, Iredale JP, Satsangi J.

Mucosal Immunol. 2018 Jan;11(1):120-130. doi: 10.1038/mi.2017.31. Epub 2017 Apr 12.

23.

NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth.

Chen L, Wilson JE, Koenigsknecht MJ, Chou WC, Montgomery SA, Truax AD, Brickey WJ, Packey CD, Maharshak N, Matsushima GK, Plevy SE, Young VB, Sartor RB, Ting JP.

Nat Immunol. 2017 May;18(5):541-551. doi: 10.1038/ni.3690. Epub 2017 Mar 13. Erratum in: Nat Immunol. 2017 Oct 18;18(11):1270. Nat Immunol. 2017 Jul 19;18(8):951.

24.

Molecular classification of Crohn's disease reveals two clinically relevant subtypes.

Weiser M, Simon JM, Kochar B, Tovar A, Israel JW, Robinson A, Gipson GR, Schaner MS, Herfarth HH, Sartor RB, McGovern DPB, Rahbar R, Sadiq TS, Koruda MJ, Furey TS, Sheikh SZ.

Gut. 2018 Jan;67(1):36-42. doi: 10.1136/gutjnl-2016-312518. Epub 2016 Oct 14.

25.

Roles for Intestinal Bacteria, Viruses, and Fungi in Pathogenesis of Inflammatory Bowel Diseases and Therapeutic Approaches.

Sartor RB, Wu GD.

Gastroenterology. 2017 Feb;152(2):327-339.e4. doi: 10.1053/j.gastro.2016.10.012. Epub 2016 Oct 18. Review.

26.

Characterization of candidate genes in inflammatory bowel disease-associated risk loci.

Peloquin JM, Goel G, Kong L, Huang H, Haritunians T, Sartor RB, Daly MJ, Newberry RD, McGovern DP, Yajnik V, Lira SA, Xavier RJ.

JCI Insight. 2016 Aug 18;1(13):e87899. doi: 10.1172/jci.insight.87899.

27.

Rifaximin Exerts Beneficial Effects Independent of its Ability to Alter Microbiota Composition.

Kang DJ, Kakiyama G, Betrapally NS, Herzog J, Nittono H, Hylemon PB, Zhou H, Carroll I, Yang J, Gillevet PM, Jiao C, Takei H, Pandak WM, Iida T, Heuman DM, Fan S, Fiehn O, Kurosawa T, Sikaroodi M, Sartor RB, Bajaj JS.

Clin Transl Gastroenterol. 2016 Aug 25;7(8):e187. doi: 10.1038/ctg.2016.44.

28.

Gut microbiota drive the development of neuroinflammatory response in cirrhosis in mice.

Kang DJ, Betrapally NS, Ghosh SA, Sartor RB, Hylemon PB, Gillevet PM, Sanyal AJ, Heuman DM, Carl D, Zhou H, Liu R, Wang X, Yang J, Jiao C, Herzog J, Lippman HR, Sikaroodi M, Brown RR, Bajaj JS.

Hepatology. 2016 Oct;64(4):1232-48. doi: 10.1002/hep.28696. Epub 2016 Jul 29.

29.

Alterations to chromatin in intestinal macrophages link IL-10 deficiency to inappropriate inflammatory responses.

Simon JM, Davis JP, Lee SE, Schaner MR, Gipson GR, Weiser M, Sartor RB, Herfarth HH, Rahbar R, Sadiq TS, Koruda MJ, McGovern DP, Lieb JD, Mohlke KL, Furey TS, Sheikh SZ.

Eur J Immunol. 2016 Aug;46(8):1912-25. doi: 10.1002/eji.201546237. Epub 2016 Jun 1.

30.
31.

Lymphoid-Tissue-Resident Commensal Bacteria Promote Members of the IL-10 Cytokine Family to Establish Mutualism.

Fung TC, Bessman NJ, Hepworth MR, Kumar N, Shibata N, Kobuley D, Wang K, Ziegler CGK, Goc J, Shima T, Umesaki Y, Sartor RB, Sullivan KV, Lawley TD, Kunisawa J, Kiyono H, Sonnenberg GF.

Immunity. 2016 Mar 15;44(3):634-646. doi: 10.1016/j.immuni.2016.02.019.

32.

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk.

Zhu W, Gregory JC, Org E, Buffa JA, Gupta N, Wang Z, Li L, Fu X, Wu Y, Mehrabian M, Sartor RB, McIntyre TM, Silverstein RL, Tang WHW, DiDonato JA, Brown JM, Lusis AJ, Hazen SL.

Cell. 2016 Mar 24;165(1):111-124. doi: 10.1016/j.cell.2016.02.011. Epub 2016 Mar 10.

33.

Review article: the potential mechanisms of action of rifaximin in the management of inflammatory bowel diseases.

Sartor RB.

Aliment Pharmacol Ther. 2016 Jan;43 Suppl 1:27-36. doi: 10.1111/apt.13436. Review.

34.

Adherent-Invasive Escherichia coli Production of Cellulose Influences Iron-Induced Bacterial Aggregation, Phagocytosis, and Induction of Colitis.

Ellermann M, Huh EY, Liu B, Carroll IM, Tamayo R, Sartor RB.

Infect Immun. 2015 Oct;83(10):4068-80. doi: 10.1128/IAI.00904-15. Epub 2015 Jul 27.

35.

MicroRNAs Classify Different Disease Behavior Phenotypes of Crohn's Disease and May Have Prognostic Utility.

Peck BC, Weiser M, Lee SE, Gipson GR, Iyer VB, Sartor RB, Herfarth HH, Long MD, Hansen JJ, Isaacs KL, Trembath DG, Rahbar R, Sadiq TS, Furey TS, Sethupathy P, Sheikh SZ.

Inflamm Bowel Dis. 2015 Sep;21(9):2178-87. doi: 10.1097/MIB.0000000000000478.

36.

Advances in understanding Giardia: determinants and mechanisms of chronic sequelae.

Bartelt LA, Sartor RB.

F1000Prime Rep. 2015 May 26;7:62. doi: 10.12703/P7-62. eCollection 2015. Review.

37.

Surface-Associated Lipoproteins Link Enterococcus faecalis Virulence to Colitogenic Activity in IL-10-Deficient Mice Independent of Their Expression Levels.

Ocvirk S, Sava IG, Lengfelder I, Lagkouvardos I, Steck N, Roh JH, Tchaptchet S, Bao Y, Hansen JJ, Huebner J, Carroll IM, Murray BE, Sartor RB, Haller D.

PLoS Pathog. 2015 Jun 12;11(6):e1004911. doi: 10.1371/journal.ppat.1004911. eCollection 2015 Jun.

38.
39.

The Immunostimulatory Nature of NSAIDs in Inflammatory Bowel Disease.

Morse D, Sartor RB.

Inflamm Bowel Dis. 2015 Jul;21(7):E11. doi: 10.1097/MIB.0000000000000407. No abstract available.

PMID:
25919977
40.

Enterococcus faecalis Gelatinase Mediates Intestinal Permeability via Protease-Activated Receptor 2.

Maharshak N, Huh EY, Paiboonrungruang C, Shanahan M, Thurlow L, Herzog J, Djukic Z, Orlando R, Pawlinski R, Ellermann M, Borst L, Patel S, Dotan I, Sartor RB, Carroll IM.

Infect Immun. 2015 Jul;83(7):2762-70. doi: 10.1128/IAI.00425-15. Epub 2015 Apr 27.

41.

High throughput sequencing reveals distinct microbial populations within the mucosal and luminal niches in healthy individuals.

Ringel Y, Maharshak N, Ringel-Kulka T, Wolber EA, Sartor RB, Carroll IM.

Gut Microbes. 2015;6(3):173-81. doi: 10.1080/19490976.2015.1044711.

42.

Gut microbiota: Optimal sampling of the intestinal microbiota for research.

Sartor RB.

Nat Rev Gastroenterol Hepatol. 2015 May;12(5):253-4. doi: 10.1038/nrgastro.2015.46. Epub 2015 Mar 24. No abstract available.

PMID:
25802025
43.

Small heat-shock proteins, IbpAB, protect non-pathogenic Escherichia coli from killing by macrophage-derived reactive oxygen species.

Goeser L, Fan TJ, Tchaptchet S, Stasulli N, Goldman WE, Sartor RB, Hansen JJ.

PLoS One. 2015 Mar 23;10(3):e0120249. doi: 10.1371/journal.pone.0120249. eCollection 2015.

44.

Response to the letter by Brotherton regarding "insoluble fiber and intestinal microbiota metabolism".

Goldsmith JR, Sartor RB.

J Gastroenterol. 2015 Apr;50(4):492-3. doi: 10.1007/s00535-015-1044-5. Epub 2015 Feb 7. No abstract available.

PMID:
25663612
45.

Therapeutic Manipulation of the Microbiome in IBD: Current Results and Future Approaches.

Hansen JJ, Sartor RB.

Curr Treat Options Gastroenterol. 2015 Mar;13(1):105-20. doi: 10.1007/s11938-014-0042-7.

46.

Preventing postoperative recurrence of Crohn's disease: how can we improve results?

Sartor RB.

Clin Gastroenterol Hepatol. 2015 May;13(5):936-9. doi: 10.1016/j.cgh.2014.12.027. Epub 2015 Jan 6. No abstract available.

PMID:
25576478
47.

The antipsychotic olanzapine interacts with the gut microbiome to cause weight gain in mouse.

Morgan AP, Crowley JJ, Nonneman RJ, Quackenbush CR, Miller CN, Ryan AK, Bogue MA, Paredes SH, Yourstone S, Carroll IM, Kawula TH, Bower MA, Sartor RB, Sullivan PF.

PLoS One. 2014 Dec 15;9(12):e115225. doi: 10.1371/journal.pone.0115225. eCollection 2014.

48.

Inflammation-associated adherent-invasive Escherichia coli are enriched in pathways for use of propanediol and iron and M-cell translocation.

Dogan B, Suzuki H, Herlekar D, Sartor RB, Campbell BJ, Roberts CL, Stewart K, Scherl EJ, Araz Y, Bitar PP, Lefébure T, Chandler B, Schukken YH, Stanhope MJ, Simpson KW.

Inflamm Bowel Dis. 2014 Nov;20(11):1919-32. doi: 10.1097/MIB.0000000000000183.

PMID:
25230163
49.

The intestinal microbiota in inflammatory bowel diseases.

Sartor RB.

Nestle Nutr Inst Workshop Ser. 2014;79:29-39. doi: 10.1159/000360674. Epub 2014 Sep 5.

PMID:
25227293
50.

TLR5-mediated sensing of gut microbiota is necessary for antibody responses to seasonal influenza vaccination.

Oh JZ, Ravindran R, Chassaing B, Carvalho FA, Maddur MS, Bower M, Hakimpour P, Gill KP, Nakaya HI, Yarovinsky F, Sartor RB, Gewirtz AT, Pulendran B.

Immunity. 2014 Sep 18;41(3):478-492. doi: 10.1016/j.immuni.2014.08.009. Epub 2014 Sep 11.

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