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Items: 11


Generation of antibody-based therapeutics targeting the Idiotype of B-cell Malignancies.

Weiss E, Sarnovsky R, Ho M, Arons E, Kreitman R, Angelus E, Antignani A, FitzGerald D.

Antib Ther. 2019 Jan;2(1):1-10. doi: 10.1093/abt/tby012. Epub 2018 Dec 27.


Analgesia by Deletion of Spinal Neurokinin 1 Receptor Expressing Neurons Using a Bioengineered Substance P-Pseudomonas Exotoxin Conjugate.

Iadarola MJ, Sapio MR, Wang X, Carrero H, Virata-Theimer ML, Sarnovsky R, Mannes AJ, FitzGerald DJ.

Mol Pain. 2017 Jan-Dec;13:1744806917727657. doi: 10.1177/1744806917727657.


Targeting a Cancer-Specific Epitope of the Epidermal Growth Factor Receptor in Triple-Negative Breast Cancer.

Simon N, Antignani A, Sarnovsky R, Hewitt SM, FitzGerald D.

J Natl Cancer Inst. 2016 Apr 13;108(8). doi: 10.1093/jnci/djw028. Print 2016 Aug.


ABT-737 promotes the dislocation of ER luminal proteins to the cytosol, including pseudomonas exotoxin.

Antignani A, Sarnovsky R, FitzGerald DJ.

Mol Cancer Ther. 2014 Jun;13(6):1655-63. doi: 10.1158/1535-7163.MCT-13-0998. Epub 2014 Apr 16.


Direct interaction between the TnsA and TnsB subunits controls the heteromeric Tn7 transposase.

Choi KY, Li Y, Sarnovsky R, Craig NL.

Proc Natl Acad Sci U S A. 2013 May 28;110(22):E2038-45. doi: 10.1073/pnas.1305716110. Epub 2013 May 14.


Initial characterization of an immunotoxin constructed from domains II and III of cholera exotoxin.

Sarnovsky R, Tendler T, Makowski M, Kiley M, Antignani A, Traini R, Zhang J, Hassan R, FitzGerald DJ.

Cancer Immunol Immunother. 2010 May;59(5):737-46. doi: 10.1007/s00262-009-0794-4. Epub 2009 Nov 29.


Proteolytic cleavage of a C-terminal prosequence, leading to autoprocessing at the N Terminus, activates leucine aminopeptidase from Pseudomonas aeruginosa.

Sarnovsky R, Rea J, Makowski M, Hertle R, Kelly C, Antignani A, Pastrana DV, Fitzgerald DJ.

J Biol Chem. 2009 Apr 10;284(15):10243-53. doi: 10.1074/jbc.M808686200. Epub 2009 Feb 11.


Large-scale mutagenesis of the yeast genome using a Tn7-derived multipurpose transposon.

Kumar A, Seringhaus M, Biery MC, Sarnovsky RJ, Umansky L, Piccirillo S, Heidtman M, Cheung KH, Dobry CJ, Gerstein MB, Craig NL, Snyder M.

Genome Res. 2004 Oct;14(10A):1975-86.


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