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Items: 39

1.

Mechanistic Insights into Cytosine-N3 Methylation by DNA Methyltransferase DNMT3A.

Dukatz M, Requena CE, Emperle M, Hajkova P, Sarkies P, Jeltsch A.

J Mol Biol. 2019 Jun 21. pii: S0022-2836(19)30400-0. doi: 10.1016/j.jmb.2019.06.015. [Epub ahead of print]

PMID:
31229457
2.

Molecular mechanisms of epigenetic inheritance: Possible evolutionary implications.

Sarkies P.

Semin Cell Dev Biol. 2019 Jun 21. pii: S1084-9521(18)30148-4. doi: 10.1016/j.semcdb.2019.06.005. [Epub ahead of print] Review.

3.

PETISCO is a novel protein complex required for 21U RNA biogenesis and embryonic viability.

Cordeiro Rodrigues RJ, de Jesus Domingues AM, Hellmann S, Dietz S, de Albuquerque BFM, Renz C, Ulrich HD, Sarkies P, Butter F, Ketting RF.

Genes Dev. 2019 Jul 1;33(13-14):857-870. doi: 10.1101/gad.322446.118. Epub 2019 May 30.

4.

The meiotic phosphatase GSP-2/PP1 promotes germline immortality and small RNA-mediated genome silencing.

Billmyre KK, Doebley AL, Spichal M, Heestand B, Belicard T, Sato-Carlton A, Flibotte S, Simon M, Gnazzo M, Skop A, Moerman D, Carlton PM, Sarkies P, Ahmed S.

PLoS Genet. 2019 Mar 28;15(3):e1008004. doi: 10.1371/journal.pgen.1008004. eCollection 2019 Mar.

5.

Comparative Epigenomics Reveals that RNA Polymerase II Pausing and Chromatin Domain Organization Control Nematode piRNA Biogenesis.

Beltran T, Barroso C, Birkle TY, Stevens L, Schwartz HT, Sternberg PW, Fradin H, Gunsalus K, Piano F, Sharma G, Cerrato C, Ahringer J, Martínez-Pérez E, Blaxter M, Sarkies P.

Dev Cell. 2019 Mar 25;48(6):793-810.e6. doi: 10.1016/j.devcel.2018.12.026. Epub 2019 Jan 31.

6.

The piRNA pathway responds to environmental signals to establish intergenerational adaptation to stress.

Belicard T, Jareosettasin P, Sarkies P.

BMC Biol. 2018 Sep 18;16(1):103. doi: 10.1186/s12915-018-0571-y.

7.

Evolutionary analysis indicates that DNA alkylation damage is a byproduct of cytosine DNA methyltransferase activity.

Rošić S, Amouroux R, Requena CE, Gomes A, Emperle M, Beltran T, Rane JK, Linnett S, Selkirk ME, Schiffer PH, Bancroft AJ, Grencis RK, Jeltsch A, Hajkova P, Sarkies P.

Nat Genet. 2018 Mar;50(3):452-459. doi: 10.1038/s41588-018-0061-8. Epub 2018 Feb 19.

8.

Natural Infection of C. elegans by an Oomycete Reveals a New Pathogen-Specific Immune Response.

Osman GA, Fasseas MK, Koneru SL, Essmann CL, Kyrou K, Srinivasan MA, Zhang G, Sarkies P, Félix MA, Barkoulas M.

Curr Biol. 2018 Feb 19;28(4):640-648.e5. doi: 10.1016/j.cub.2018.01.029.

9.

Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence against transposable elements.

Lewis SH, Quarles KA, Yang Y, Tanguy M, Frézal L, Smith SA, Sharma PP, Cordaux R, Gilbert C, Giraud I, Collins DH, Zamore PD, Miska EA, Sarkies P, Jiggins FM.

Nat Ecol Evol. 2018 Jan;2(1):174-181. doi: 10.1038/s41559-017-0403-4. Epub 2017 Dec 4.

10.

An Alternative STAT Signaling Pathway Acts in Viral Immunity in Caenorhabditis elegans.

Tanguy M, Véron L, Stempor P, Ahringer J, Sarkies P, Miska EA.

MBio. 2017 Sep 5;8(5). pii: e00924-17. doi: 10.1128/mBio.00924-17.

11.

Tissue microarray methodology identifies complement pathway activation and dysregulation in progressive multiple sclerosis.

Loveless S, Neal JW, Howell OW, Harding KE, Sarkies P, Evans R, Bevan RJ, Hakobyan S, Harris CL, Robertson NP, Morgan BP.

Brain Pathol. 2018 Jul;28(4):507-520. doi: 10.1111/bpa.12546. Epub 2017 Jul 30.

PMID:
28707765
12.

miR-182 Regulates Slit2-Mediated Axon Guidance by Modulating the Local Translation of a Specific mRNA.

Bellon A, Iyer A, Bridi S, Lee FCY, Ovando-Vázquez C, Corradi E, Longhi S, Roccuzzo M, Strohbuecker S, Naik S, Sarkies P, Miska E, Abreu-Goodger C, Holt CE, Baudet ML.

Cell Rep. 2017 Jan 31;18(5):1171-1186. doi: 10.1016/j.celrep.2016.12.093.

13.

The genome of the crustacean Parhyale hawaiensis, a model for animal development, regeneration, immunity and lignocellulose digestion.

Kao D, Lai AG, Stamataki E, Rosic S, Konstantinides N, Jarvis E, Di Donfrancesco A, Pouchkina-Stancheva N, Sémon M, Grillo M, Bruce H, Kumar S, Siwanowicz I, Le A, Lemire A, Eisen MB, Extavour C, Browne WE, Wolff C, Averof M, Patel NH, Sarkies P, Pavlopoulos A, Aboobaker A.

Elife. 2016 Nov 16;5. pii: e20062. doi: 10.7554/eLife.20062.

14.

Specific down-regulation of spermatogenesis genes targeted by 22G RNAs in hybrid sterile males associated with an X-Chromosome introgression.

Li R, Ren X, Bi Y, Ho VW, Hsieh CL, Young A, Zhang Z, Lin T, Zhao Y, Miao L, Sarkies P, Zhao Z.

Genome Res. 2016 Sep;26(9):1219-32. doi: 10.1101/gr.204479.116. Epub 2016 May 18.

15.

Wolbachia Blocks Viral Genome Replication Early in Infection without a Transcriptional Response by the Endosymbiont or Host Small RNA Pathways.

Rainey SM, Martinez J, McFarlane M, Juneja P, Sarkies P, Lulla A, Schnettler E, Varjak M, Merits A, Miska EA, Jiggins FM, Kohl A.

PLoS Pathog. 2016 Apr 18;12(4):e1005536. doi: 10.1371/journal.ppat.1005536. eCollection 2016 Apr. Erratum in: PLoS Pathog. 2016 May;12(5):e1005639.

16.

Antiviral RNA Interference against Orsay Virus Is neither Systemic nor Transgenerational in Caenorhabditis elegans.

Ashe A, Sarkies P, Le Pen J, Tanguy M, Miska EA.

J Virol. 2015 Dec;89(23):12035-46. doi: 10.1128/JVI.03664-14. Epub 2015 Sep 23.

17.

When Medical News Comes from Press Releases-A Case Study of Pancreatic Cancer and Processed Meat.

Taylor JW, Long M, Ashley E, Denning A, Gout B, Hansen K, Huws T, Jennings L, Quinn S, Sarkies P, Wojtowicz A, Newton PM.

PLoS One. 2015 Jun 17;10(6):e0127848. doi: 10.1371/journal.pone.0127848. eCollection 2015.

18.

E. coli OxyS non-coding RNA does not trigger RNAi in C. elegans.

Akay A, Sarkies P, Miska EA.

Sci Rep. 2015 Apr 15;5:9597. doi: 10.1038/srep09597.

19.

Tertiary siRNAs mediate paramutation in C. elegans.

Sapetschnig A, Sarkies P, Lehrbach NJ, Miska EA.

PLoS Genet. 2015 Mar 26;11(3):e1005078. doi: 10.1371/journal.pgen.1005078. eCollection 2015 Mar.

20.

Ancient and novel small RNA pathways compensate for the loss of piRNAs in multiple independent nematode lineages.

Sarkies P, Selkirk ME, Jones JT, Blok V, Boothby T, Goldstein B, Hanelt B, Ardila-Garcia A, Fast NM, Schiffer PM, Kraus C, Taylor MJ, Koutsovoulos G, Blaxter ML, Miska EA.

PLoS Biol. 2015 Feb 10;13(2):e1002061. doi: 10.1371/journal.pbio.1002061. eCollection 2015 Feb.

21.

Caenorhabditis elegans RSD-2 and RSD-6 promote germ cell immortality by maintaining small interfering RNA populations.

Sakaguchi A, Sarkies P, Simon M, Doebley AL, Goldstein LD, Hedges A, Ikegami K, Alvares SM, Yang L, LaRocque JR, Hall J, Miska EA, Ahmed S.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):E4323-31. doi: 10.1073/pnas.1406131111. Epub 2014 Sep 25.

22.

Histone H3.3 is required to maintain replication fork progression after UV damage.

Frey A, Listovsky T, Guilbaud G, Sarkies P, Sale JE.

Curr Biol. 2014 Sep 22;24(18):2195-2201. doi: 10.1016/j.cub.2014.07.077. Epub 2014 Sep 4.

23.

Determinants of G quadruplex-induced epigenetic instability in REV1-deficient cells.

Schiavone D, Guilbaud G, Murat P, Papadopoulou C, Sarkies P, Prioleau MN, Balasubramanian S, Sale JE.

EMBO J. 2014 Nov 3;33(21):2507-20. doi: 10.15252/embj.201488398. Epub 2014 Sep 4.

24.

Small RNAs break out: the molecular cell biology of mobile small RNAs.

Sarkies P, Miska EA.

Nat Rev Mol Cell Biol. 2014 Aug;15(8):525-35. doi: 10.1038/nrm3840. Review.

PMID:
25053358
25.

Reduced insulin/IGF-1 signaling restores germ cell immortality to Caenorhabditis elegans Piwi mutants.

Simon M, Sarkies P, Ikegami K, Doebley AL, Goldstein LD, Mitchell J, Sakaguchi A, Miska EA, Ahmed S.

Cell Rep. 2014 May 8;7(3):762-73. doi: 10.1016/j.celrep.2014.03.056. Epub 2014 Apr 24.

26.

Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice.

Gapp K, Jawaid A, Sarkies P, Bohacek J, Pelczar P, Prados J, Farinelli L, Miska E, Mansuy IM.

Nat Neurosci. 2014 May;17(5):667-9. doi: 10.1038/nn.3695. Epub 2014 Apr 13.

27.

PRDE-1 is a nuclear factor essential for the biogenesis of Ruby motif-dependent piRNAs in C. elegans.

Weick EM, Sarkies P, Silva N, Chen RA, Moss SM, Cording AC, Ahringer J, Martinez-Perez E, Miska EA.

Genes Dev. 2014 Apr 1;28(7):783-96. doi: 10.1101/gad.238105.114.

28.

A deletion polymorphism in the Caenorhabditis elegans RIG-I homolog disables viral RNA dicing and antiviral immunity.

Ashe A, Bélicard T, Le Pen J, Sarkies P, Frézal L, Lehrbach NJ, Félix MA, Miska EA.

Elife. 2013 Oct 8;2:e00994. doi: 10.7554/eLife.00994.

29.

Molecular biology. Is there social RNA?

Sarkies P, Miska EA.

Science. 2013 Aug 2;341(6145):467-8. doi: 10.1126/science.1243175. No abstract available.

PMID:
23908213
30.

RNAi pathways in the recognition of foreign RNA: antiviral responses and host-parasite interactions in nematodes.

Sarkies P, Miska EA.

Biochem Soc Trans. 2013 Aug;41(4):876-80. doi: 10.1042/BST20130021. Review.

PMID:
23863148
31.

Competition between virus-derived and endogenous small RNAs regulates gene expression in Caenorhabditis elegans.

Sarkies P, Ashe A, Le Pen J, McKie MA, Miska EA.

Genome Res. 2013 Aug;23(8):1258-70. doi: 10.1101/gr.153296.112. Epub 2013 Jun 28.

32.

piRNAs can trigger a multigenerational epigenetic memory in the germline of C. elegans.

Ashe A, Sapetschnig A, Weick EM, Mitchell J, Bagijn MP, Cording AC, Doebley AL, Goldstein LD, Lehrbach NJ, Le Pen J, Pintacuda G, Sakaguchi A, Sarkies P, Ahmed S, Miska EA.

Cell. 2012 Jul 6;150(1):88-99. doi: 10.1016/j.cell.2012.06.018. Epub 2012 Jun 25.

33.

Cellular epigenetic stability and cancer.

Sarkies P, Sale JE.

Trends Genet. 2012 Mar;28(3):118-27. doi: 10.1016/j.tig.2011.11.005. Epub 2012 Jan 5. Review.

PMID:
22226176
34.

FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA.

Sarkies P, Murat P, Phillips LG, Patel KJ, Balasubramanian S, Sale JE.

Nucleic Acids Res. 2012 Feb;40(4):1485-98. doi: 10.1093/nar/gkr868. Epub 2011 Oct 22.

35.

Propagation of histone marks and epigenetic memory during normal and interrupted DNA replication.

Sarkies P, Sale JE.

Cell Mol Life Sci. 2012 Mar;69(5):697-716. doi: 10.1007/s00018-011-0824-1. Epub 2011 Oct 2. Review.

PMID:
21964926
36.

Epigenetic instability due to defective replication of structured DNA.

Sarkies P, Reams C, Simpson LJ, Sale JE.

Mol Cell. 2010 Dec 10;40(5):703-13. doi: 10.1016/j.molcel.2010.11.009.

37.

Motogenic sites in human fibronectin are masked by long range interactions.

Vakonakis I, Staunton D, Ellis IR, Sarkies P, Flanagan A, Schor AM, Schor SL, Campbell ID.

J Biol Chem. 2009 Jun 5;284(23):15668-75. doi: 10.1074/jbc.M109.003673. Epub 2009 Apr 14.

38.

Genetic selection of activatory mutations in KcsA.

Paynter JJ, Sarkies P, Andres-Enguix I, Tucker SJ.

Channels (Austin). 2008 Nov-Dec;2(6):413-8. Epub 2008 Nov 27.

39.

Novel geometry for simple accurate tuning of lasers.

Greenhalgh DA, Sarkies PH.

Appl Opt. 1982 Sep 15;21(18):3234-6. doi: 10.1364/AO.21.003234. No abstract available.

PMID:
20396214

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