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Items: 1 to 50 of 84

1.

First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant FGF19 Signaling as a Driver Event in Hepatocellular Carcinoma.

Kim RD, Sarker D, Meyer T, Yau T, Macarulla T, Park JW, Choo SP, Hollebecque A, Sung MW, Lim HY, Mazzaferro V, Trojan J, Zhu AX, Yoon JH, Sharma S, Lin ZZ, Chan SL, Faivre S, Feun LG, Yen CJ, Dufour JF, Palmer DH, Llovet JM, Manoogian M, Tugnait M, Stransky N, Hagel M, Kohl NE, Lengauer C, Sherwin CA, Schmidt-Kittler O, Hoeflich KP, Shi H, Wolf BB, Kang YK.

Cancer Discov. 2019 Dec;9(12):1696-1707. doi: 10.1158/2159-8290.CD-19-0555. Epub 2019 Oct 1.

PMID:
31575541
2.

Chronic inflammation markers are associated with risk of pancreatic cancer in the Swedish AMORIS cohort study.

Sollie S, Michaud DS, Sarker D, Karagiannis SN, Josephs DH, Hammar N, Santaolalla A, Walldius G, Garmo H, Holmberg L, Jungner I, Van Hemelrijck M.

BMC Cancer. 2019 Aug 29;19(1):858. doi: 10.1186/s12885-019-6082-6.

3.

Manipulating Localized Vibrations of Interstitial Te for Ultra-High Thermoelectric Efficiency in p-Type Cu-In-Te Systems.

Ren T, Han Z, Ying P, Li X, Li X, Lin X, Sarker D, Cui J.

ACS Appl Mater Interfaces. 2019 Sep 4;11(35):32192-32199. doi: 10.1021/acsami.9b12256. Epub 2019 Aug 23.

PMID:
31442031
4.

Offensive waste valorisation in the UK: Assessment of the potentials for absorbent hygiene product (AHP) recycling.

Takaya CA, Cooper I, Berg M, Carpenter J, Muir R, Brittle S, Sarker DK.

Waste Manag. 2019 Apr 1;88:56-70. doi: 10.1016/j.wasman.2019.03.022. Epub 2019 Mar 20.

PMID:
31079651
5.

Delayed adverse events in phase I trials of molecularly targeted and cytotoxic agents.

Jordan EJ, Spicer J, Sarker D.

Oncotarget. 2018 Sep 21;9(74):33961-33971. doi: 10.18632/oncotarget.26104. eCollection 2018 Sep 21.

6.

Improving stormwater quality at source using catch basin inserts.

Alam MZ, Anwar AHMF, Heitz A, Sarker DC.

J Environ Manage. 2018 Dec 15;228:393-404. doi: 10.1016/j.jenvman.2018.08.070. Epub 2018 Sep 20.

PMID:
30243075
7.

A phase I study to assess afatinib in combination with carboplatin or with carboplatin plus paclitaxel in patients with advanced solid tumors.

O'Brien MER, Sarker D, Bhosle J, Thillai K, Yap TA, Uttenreuther-Fischer M, Pemberton K, Jin X, Wiebe S, de Bono J, Spicer J.

Cancer Chemother Pharmacol. 2018 Nov;82(5):757-766. doi: 10.1007/s00280-018-3661-1. Epub 2018 Aug 7.

8.

First-in-human study of LY3039478, an oral Notch signaling inhibitor in advanced or metastatic cancer.

Massard C, Azaro A, Soria JC, Lassen U, Le Tourneau C, Sarker D, Smith C, Ohnmacht U, Oakley G, Patel BKR, Yuen ESM, Benhadji KA, Rodon J.

Ann Oncol. 2018 Sep 1;29(9):1911-1917. doi: 10.1093/annonc/mdy244.

9.

Hepatocellular Carcinoma as a Complication of Vascular Disease of the Liver After Fontan Procedure.

Mazzarelli C, Cannon MD, Hudson M, Heaton N, Sarker D, Kane P, Quaglia A, Suddle A.

Hepatology. 2019 Feb;69(2):911-913. doi: 10.1002/hep.30194. Epub 2018 Dec 28. No abstract available.

PMID:
30055116
10.

Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial.

Zhu AX, Finn RS, Edeline J, Cattan S, Ogasawara S, Palmer D, Verslype C, Zagonel V, Fartoux L, Vogel A, Sarker D, Verset G, Chan SL, Knox J, Daniele B, Webber AL, Ebbinghaus SW, Ma J, Siegel AB, Cheng AL, Kudo M; KEYNOTE-224 investigators.

Lancet Oncol. 2018 Jul;19(7):940-952. doi: 10.1016/S1470-2045(18)30351-6. Epub 2018 Jun 3. Erratum in: Lancet Oncol. 2018 Sep;19(9):e440.

PMID:
29875066
11.

Phase III randomized study of second line ADI-PEG 20 plus best supportive care versus placebo plus best supportive care in patients with advanced hepatocellular carcinoma.

Abou-Alfa GK, Qin S, Ryoo BY, Lu SN, Yen CJ, Feng YH, Lim HY, Izzo F, Colombo M, Sarker D, Bolondi L, Vaccaro G, Harris WP, Chen Z, Hubner RA, Meyer T, Sun W, Harding JJ, Hollywood EM, Ma J, Wan PJ, Ly M, Bomalaski J, Johnston A, Lin CC, Chao Y, Chen LT.

Ann Oncol. 2018 Jun 1;29(6):1402-1408. doi: 10.1093/annonc/mdy101.

12.

PAK4 pathway as a potential therapeutic target in pancreatic cancer.

Thillai K, Sarker D, Wells C.

Future Oncol. 2018 Mar;14(7):579-582. doi: 10.2217/fon-2017-0458. Epub 2018 Mar 6. Review. No abstract available.

13.

PET-PANC: multicentre prospective diagnostic accuracy and health economic analysis study of the impact of combined modality 18fluorine-2-fluoro-2-deoxy-d-glucose positron emission tomography with computed tomography scanning in the diagnosis and management of pancreatic cancer.

Ghaneh P, Hanson R, Titman A, Lancaster G, Plumpton C, Lloyd-Williams H, Yeo ST, Edwards RT, Johnson C, Abu Hilal M, Higginson AP, Armstrong T, Smith A, Scarsbrook A, McKay C, Carter R, Sutcliffe RP, Bramhall S, Kocher HM, Cunningham D, Pereira SP, Davidson B, Chang D, Khan S, Zealley I, Sarker D, Al Sarireh B, Charnley R, Lobo D, Nicolson M, Halloran C, Raraty M, Sutton R, Vinjamuri S, Evans J, Campbell F, Deeks J, Sanghera B, Wong WL, Neoptolemos JP.

Health Technol Assess. 2018 Feb;22(7):1-114. doi: 10.3310/hta22070.

14.

Evidence of local structural influence on the shape driven magnetic anisotropy in electronically excited Ni nanoparticles embedded in SiO2 matrix.

Sarker D, Bhattacharya S, Kumar H, Srivastava P, Ghosh S.

Sci Rep. 2018 Jan 18;8(1):1040. doi: 10.1038/s41598-017-18731-x.

15.

Architectures and Mechanical Properties of Drugs and Complexes of Surface-Active Compounds at Air-Water and Oil-Water Interfaces.

Sarker DK.

Curr Drug Discov Technol. 2019;16(1):11-29. doi: 10.2174/1570163814666171117132202.

PMID:
29149812
16.

Acacia nilotica leaf improves insulin resistance and hyperglycemia associated acute hepatic injury and nephrotoxicity by improving systemic antioxidant status in diabetic mice.

Saha MR, Dey P, Sarkar I, De Sarker D, Haldar B, Chaudhuri TK, Sen A.

J Ethnopharmacol. 2018 Jan 10;210:275-286. doi: 10.1016/j.jep.2017.08.036. Epub 2017 Aug 30.

PMID:
28859934
17.

Histological heterogeneity in primary and metastatic classic combined hepatocellular-cholangiocarcinoma: a case series.

De Vito C, Sarker D, Ross P, Heaton N, Quaglia A.

Virchows Arch. 2017 Nov;471(5):619-629. doi: 10.1007/s00428-017-2196-x. Epub 2017 Jul 13.

PMID:
28707055
18.

Hepatocellular Carcinoma in Perinatally Acquired HIV and HBV Coinfection: A Case Report.

Seers T, Sarker D, Ross P, Heaton N, Suddle A, Lyall H, Tudor-Williams G, Fidler S, Foster C.

Pediatr Infect Dis J. 2017 Dec;36(12):1156-1158. doi: 10.1097/INF.0000000000001662.

PMID:
28650418
19.

Phosphorous removal from aqueous solution can be enhanced through the calcination of lime sludge.

Bal Krishna KC, Niaz MR, Sarker DC, Jansen T.

J Environ Manage. 2017 Sep 15;200:359-365. doi: 10.1016/j.jenvman.2017.06.003. Epub 2017 Jun 6.

PMID:
28599219
20.

Effect of Obesity on Hemoglobin Concentration.

Akter R, Nessa A, Sarker D, Yesmin M.

Mymensingh Med J. 2017 Apr;26(2):230-234.

PMID:
28588155
21.

Diversity of the genus Ocimum (Lamiaceae) through morpho-molecular (RAPD) and chemical (GC-MS) analysis.

Chowdhury T, Mandal A, Roy SC, De Sarker D.

J Genet Eng Biotechnol. 2017 Jun;15(1):275-286. doi: 10.1016/j.jgeb.2016.12.004. Epub 2017 Jan 9.

22.

Preparation of liposomes containing small gold nanoparticles using electrostatic interactions.

Dichello GA, Fukuda T, Maekawa T, Whitby RLD, Mikhalovsky SV, Alavijeh M, Pannala AS, Sarker DK.

Eur J Pharm Sci. 2017 Jul 15;105:55-63. doi: 10.1016/j.ejps.2017.05.001. Epub 2017 May 3.

PMID:
28476616
23.

Assessment of genetic diversity among four orchids based on ddRAD sequencing data for conservation purposes.

Roy SC, Moitra K, De Sarker D.

Physiol Mol Biol Plants. 2017 Jan;23(1):169-183. doi: 10.1007/s12298-016-0401-z. Epub 2016 Dec 29.

24.

Characterising stormwater gross pollutants captured in catch basin inserts.

Alam MZ, Anwar AHMF, Sarker DC, Heitz A, Rothleitner C.

Sci Total Environ. 2017 May 15;586:76-86. doi: 10.1016/j.scitotenv.2017.01.210. Epub 2017 Feb 12.

PMID:
28199877
25.

Triggering of spin-flipping-modulated exchange bias in FeCo nanoparticles by electronic excitation.

Sarker D, Bhattacharya S, Srivastava P, Ghosh S.

Sci Rep. 2016 Dec 19;6:39292. doi: 10.1038/srep39292.

26.

Deciphering the link between PI3K and PAK: An opportunity to target key pathways in pancreatic cancer?

Thillai K, Lam H, Sarker D, Wells CM.

Oncotarget. 2017 Feb 21;8(8):14173-14191. doi: 10.18632/oncotarget.13309. Review.

27.

Removal of emerging perfluorooctanoic acid and perfluorooctane sulfonate contaminants from lake water.

Pramanik BK, Pramanik SK, Sarker DC, Suja F.

Environ Technol. 2017 Aug;38(15):1937-1942. doi: 10.1080/09593330.2016.1240716. Epub 2016 Oct 11.

PMID:
27666670
28.

Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: age is not a problem.

Ziogas DC, Papadatos-Pastos D, Thillai K, Korantzis I, Chowdhury R, Suddle A, O'Grady J, Al-Khadimi G, Allen N, Heaton N, Ross PJ, Sarker D.

Eur J Gastroenterol Hepatol. 2017 Jan;29(1):48-55.

PMID:
27623000
29.

Impact of ozonation, anion exchange resin and UV/H2O2 pre-treatments to control fouling of ultrafiltration membrane for drinking water treatment.

Pramanik BK, Pramanik SK, Sarker DC, Suja F.

Environ Technol. 2017 Jun;38(11):1383-1389. doi: 10.1080/09593330.2016.1228701. Epub 2016 Sep 20.

PMID:
27587007
30.

Ki-67 index and response to chemotherapy in patients with neuroendocrine tumours.

Childs A, Kirkwood A, Edeline J, Luong TV, Watkins J, Lamarca A, Alrifai D, Nsiah-Sarbeng P, Gillmore R, Mayer A, Thirlwell C, Sarker D, Valle JW, Meyer T.

Endocr Relat Cancer. 2016 Jul;23(7):563-70. doi: 10.1530/ERC-16-0099.

PMID:
27412968
31.

Effect of Acacia catechu (L.f.) Willd. on Oxidative Stress with Possible Implications in Alleviating Selected Cognitive Disorders.

Saha MR, Dey P, Begum S, De B, Chaudhuri TK, Sarker DD, Das AP, Sen A.

PLoS One. 2016 Mar 7;11(3):e0150574. doi: 10.1371/journal.pone.0150574. eCollection 2016.

32.

Assessment of haemolytic, cytotoxic and free radical scavenging activities of an underutilized fruit, Baccaurea ramiflora Lour. (Roxb.) Muell. Arg.

Saha MR, Dey P, Chaudhuri TK, Goyal AK, Sarker DD, Sen A.

Indian J Exp Biol. 2016 Feb;54(2):115-25.

PMID:
26934779
33.

Pharmacodynamic Biomarker Development for PI3K Pathway Therapeutics.

Josephs DH, Sarker D.

Transl Oncogenomics. 2016 Feb 21;7(Suppl 1):33-49. doi: 10.4137/TOG.S30529. eCollection 2015. Review.

34.

Molecularly targeted therapy for advanced hepatocellular carcinoma - a drug development crisis?

Thillai K, Ross P, Sarker D.

World J Gastrointest Oncol. 2016 Feb 15;8(2):173-85. doi: 10.4251/wjgo.v8.i2.173. Review.

35.

Unraveling The Origin of Enhanced Field Emission from Irradiated FeCo-SiO2 Nanocomposites: A Combined Experimental and First-Principles Based Study.

Sarker D, Bhattacharya S, Rodriguez RD, Sheremet E, Kabiraj D, Avasthi DK, Zahn DR, Schmidt H, Srivastava P, Ghosh S.

ACS Appl Mater Interfaces. 2016 Feb;8(7):4994-5001. doi: 10.1021/acsami.5b07937. Epub 2016 Feb 11.

PMID:
26812580
36.

Lenvatinib: a potential breakthrough in advanced hepatocellular carcinoma?

Oikonomopoulos G, Aravind P, Sarker D.

Future Oncol. 2016 Feb;12(4):465-76. doi: 10.2217/fon.15.341. Epub 2016 Jan 20. Review.

PMID:
26785762
37.

Prospects for adoptive immunotherapy of pancreatic cancer using chimeric antigen receptor-engineered T-cells.

Alrifai D, Sarker D, Maher J.

Immunopharmacol Immunotoxicol. 2016;38(1):50-60. doi: 10.3109/08923973.2015.1100204. Epub 2015 Oct 16.

PMID:
26473647
38.

Ethnobotany, traditional knowledge and socioeconomic importance of native drink among the Oraon tribe of Malda district in India.

Saha MR, Rai R, Kar P, Sen A, Sarker DD.

J Intercult Ethnopharmacol. 2015 Jan-Mar;4(1):34-9. doi: 10.5455/jice.20141202060743. Epub 2015 Jan 3.

39.

Indigenous knowledge of plants in local healthcare management practices by tribal people of Malda district, India.

Saha MR, Sarker DD, Kar P, Gupta PS, Sen A.

J Intercult Ethnopharmacol. 2014 Oct-Dec;3(4):179-85. doi: 10.5455/jice.20140630022609. Epub 2014 Jul 14.

40.

Modelling combined effect of chloramine and copper on ammonia-oxidizing microbial activity using a biostability approach.

Sarker DC, Sathasivan A, Rittmann BE.

Water Res. 2015 Nov 1;84:190-7. doi: 10.1016/j.watres.2015.07.019. Epub 2015 Jul 14.

PMID:
26233658
41.

The role of the PI3K pathway in colorectal cancer.

Papadatos-Pastos D, Rabbie R, Ross P, Sarker D.

Crit Rev Oncol Hematol. 2015 Apr;94(1):18-30. doi: 10.1016/j.critrevonc.2014.12.006. Epub 2014 Dec 25. Review.

PMID:
25591826
42.

Phase 1 dose-escalation study of S-222611, an oral reversible dual tyrosine kinase inhibitor of EGFR and HER2, in patients with solid tumours.

Spicer J, Baird R, Suder A, Cresti N, Corbacho JG, Hogarth L, Frenkel E, Matsumoto S, Kawabata I, Donaldson K, Posner J, Sarker D, Jodrell D, Plummer R.

Eur J Cancer. 2015 Jan;51(2):137-45. doi: 10.1016/j.ejca.2014.11.003. Epub 2014 Nov 27.

PMID:
25434923
43.

First-in-human phase I study of pictilisib (GDC-0941), a potent pan-class I phosphatidylinositol-3-kinase (PI3K) inhibitor, in patients with advanced solid tumors.

Sarker D, Ang JE, Baird R, Kristeleit R, Shah K, Moreno V, Clarke PA, Raynaud FI, Levy G, Ware JA, Mazina K, Lin R, Wu J, Fredrickson J, Spoerke JM, Lackner MR, Yan Y, Friedman LS, Kaye SB, Derynck MK, Workman P, de Bono JS.

Clin Cancer Res. 2015 Jan 1;21(1):77-86. doi: 10.1158/1078-0432.CCR-14-0947. Epub 2014 Nov 4.

44.

FOLFIRINOX - a new paradigm in the treatment of pancreatic cancer.

Papadatos-Pastos D, Thillai K, Rabbie R, Ross P, Sarker D.

Expert Rev Anticancer Ther. 2014 Oct;14(10):1115-25. doi: 10.1586/14737140.2014.957188. Epub 2014 Sep 10. Review.

PMID:
25204327
45.

Tubulin β-III: a novel immunohistochemical marker for intrahepatic peripheral cholangiocarcinoma.

Zen Y, Britton D, Mitra V, Pike I, Sarker D, Itoh T, Heaton N, Quaglia A.

Histopathology. 2014 Dec;65(6):784-92. doi: 10.1111/his.12497. Epub 2014 Aug 5.

PMID:
25039376
46.

Quantification of pancreatic cancer proteome and phosphorylome: indicates molecular events likely contributing to cancer and activity of drug targets.

Britton D, Zen Y, Quaglia A, Selzer S, Mitra V, Löβner C, Jung S, Böhm G, Schmid P, Prefot P, Hoehle C, Koncarevic S, Gee J, Nicholson R, Ward M, Castellano L, Stebbing J, Zucht HD, Sarker D, Heaton N, Pike I.

PLoS One. 2014 Mar 26;9(3):e90948. doi: 10.1371/journal.pone.0090948. eCollection 2014. Erratum in: PLoS One. 2014;9(8):e107077.

47.

Modelling temperature effects on ammonia-oxidising bacterial biostability in chloraminated systems.

Sarker DC, Sathasivan A, Joll CA, Heitz A.

Sci Total Environ. 2013 Jun 1;454-455:88-98. doi: 10.1016/j.scitotenv.2013.02.045. Epub 2013 Mar 26.

PMID:
23542482
48.

Effect of patient socioeconomic status on access to early-phase cancer trials.

Mohd Noor A, Sarker D, Vizor S, McLennan B, Hunter S, Suder A, Moller H, Spicer JF, Papa S.

J Clin Oncol. 2013 Jan 10;31(2):224-30. doi: 10.1200/JCO.2012.45.0999. Epub 2012 Dec 3.

PMID:
23213088
49.

Functional imaging techniques in hepatocellular carcinoma.

Goh V, Sarker D, Osmany S, Cook GJ.

Eur J Nucl Med Mol Imaging. 2012 Jun;39(6):1070-9. doi: 10.1007/s00259-012-2096-x. Epub 2012 Mar 21. Review.

PMID:
22434049
50.

Effect of nutrition education on exclusive breastfeeding for nutritional outcome of low birth weight babies.

Thakur SK, Roy SK, Paul K, Khanam M, Khatun W, Sarker D.

Eur J Clin Nutr. 2012 Mar;66(3):376-81. doi: 10.1038/ejcn.2011.182. Epub 2011 Nov 16.

PMID:
22085870

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