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Items: 46


The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity.

Billi AC, Gharaee-Kermani M, Fullmer J, Tsoi LC, Hill BD, Gruszka D, Ludwig J, Xing X, Estadt S, Wolf SJ, Rizvi SM, Berthier CC, Hodgin JB, Beamer MA, Sarkar MK, Liang Y, Uppala R, Shao S, Zeng C, Harms PW, Verhaegen ME, Voorhees JJ, Wen F, Ward NL, Dlugosz AA, Kahlenberg JM, Gudjonsson JE.

JCI Insight. 2019 Apr 18;4(8). pii: 127291. doi: 10.1172/jci.insight.127291. eCollection 2019 Apr 18.


Investigation of phytochemical constituents of anti-leukemic herbal drugs used by the traditional healers of Purulia, Birbhum and Bankura districts of West Bengal.

Sarkar MK, Vadivel V, Raja MRC, Kar Mahapatra S.

Nat Prod Res. 2019 Feb 15:1-6. doi: 10.1080/14786419.2019.1566818. [Epub ahead of print]


Hypersensitive IFN Responses in Lupus Keratinocytes Reveal Key Mechanistic Determinants in Cutaneous Lupus.

Tsoi LC, Hile GA, Berthier CC, Sarkar MK, Reed TJ, Liu J, Uppala R, Patrick M, Raja K, Xing X, Xing E, He K, Gudjonsson JE, Kahlenberg JM.

J Immunol. 2019 Apr 1;202(7):2121-2130. doi: 10.4049/jimmunol.1800650. Epub 2019 Feb 11.


Atopic Dermatitis Is an IL-13-Dominant Disease with Greater Molecular Heterogeneity Compared to Psoriasis.

Tsoi LC, Rodriguez E, Degenhardt F, Baurecht H, Wehkamp U, Volks N, Szymczak S, Swindell WR, Sarkar MK, Raja K, Shao S, Patrick M, Gao Y, Uppala R, Perez White BE, Getsios S, Harms PW, Maverakis E, Elder JT, Franke A, Gudjonsson JE, Weidinger S.

J Invest Dermatol. 2019 Jan 11. pii: S0022-202X(19)30007-7. doi: 10.1016/j.jid.2018.12.018. [Epub ahead of print]


Use of agricultural waste (coconut shell) for the synthesis of silver nanoparticles and evaluation of their antibacterial activity against selected human pathogens.

Sinsinwar S, Sarkar MK, Suriya KR, Nithyanand P, Vadivel V.

Microb Pathog. 2018 Nov;124:30-37. doi: 10.1016/j.micpath.2018.08.025. Epub 2018 Aug 16.


Potential anti-proliferative activity of AgNPs synthesized using M. longifolia in 4T1 cell line through ROS generation and cell membrane damage.

Sarkar MK, Vadivel V, Charan Raja MR, Mahapatra SK.

J Photochem Photobiol B. 2018 Sep;186:160-168. doi: 10.1016/j.jphotobiol.2018.07.014. Epub 2018 Jul 24.


Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa.

Sarkar MK, Hile GA, Tsoi LC, Xing X, Liu J, Liang Y, Berthier CC, Swindell WR, Patrick MT, Shao S, Tsou PS, Uppala R, Beamer MA, Srivastava A, Bielas SL, Harms PW, Getsios S, Elder JT, Voorhees JJ, Gudjonsson JE, Kahlenberg JM.

Ann Rheum Dis. 2018 Nov;77(11):1653-1664. doi: 10.1136/annrheumdis-2018-213197. Epub 2018 Jul 18.


Enumerating Antibiotic Susceptibility Patterns of Pseudomonas aeruginosa Isolated from Different Sources in Dhaka City.

Bhuiya M, Sarkar MKI, Sohag MH, Ali H, Roy CK, Akther L, Sarker AF.

Open Microbiol J. 2018 May 31;12:172-180. doi: 10.2174/1874285801812010172. eCollection 2018.


Utility of CD157 as a Common Leukocytes Marker for Paroxysmal Nocturnal Hemoglobinuria Screening in a Single Tube Five Color Combination.

Rahman K, Gupta R, Harankhedkar S, Gupta T, Sarkar MK, Nityanand S.

Indian J Hematol Blood Transfus. 2018 Apr;34(2):304-309. doi: 10.1007/s12288-017-0867-z. Epub 2017 Aug 22.


RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature.

Swindell WR, Beamer MA, Sarkar MK, Loftus S, Fullmer J, Xing X, Ward NL, Tsoi LC, Kahlenberg MJ, Liang Y, Gudjonsson JE.

Front Immunol. 2018 Jan 29;9:80. doi: 10.3389/fimmu.2018.00080. eCollection 2018.


RNA-seq identifies a diminished differentiation gene signature in primary monolayer keratinocytes grown from lesional and uninvolved psoriatic skin.

Swindell WR, Sarkar MK, Liang Y, Xing X, Baliwag J, Elder JT, Johnston A, Ward NL, Gudjonsson JE.

Sci Rep. 2017 Dec 22;7(1):18045. doi: 10.1038/s41598-017-18404-9.


IFN-γ and TNF-α synergism may provide a link between psoriasis and inflammatory atherogenesis.

Mehta NN, Teague HL, Swindell WR, Baumer Y, Ward NL, Xing X, Baugous B, Johnston A, Joshi AA, Silverman J, Barnes DH, Wolterink L, Nair RP, Stuart PE, Playford M, Voorhees JJ, Sarkar MK, Elder JT, Gallagher K, Ganesh SK, Gudjonsson JE.

Sci Rep. 2017 Oct 23;7(1):13831. doi: 10.1038/s41598-017-14365-1.


Transcriptional determinants of individualized inflammatory responses at anatomically separate sites.

Tsoi LC, Yang J, Liang Y, Sarkar MK, Xing X, Beamer MA, Aphale A, Raja K, Kozlow JH, Getsios S, Voorhees JJ, Kahlenberg JM, Elder JT, Gudjonsson JE.

J Allergy Clin Immunol. 2018 Feb;141(2):805-808. doi: 10.1016/j.jaci.2017.07.054. Epub 2017 Oct 13. No abstract available.


The triple-negative (CD34-/HLA-DR-/CD11b-) profile rapidly and specifically identifies an acute promyelocytic leukemia.

Rahman K, Gupta R, Singh MK, Sarkar MK, Gupta A, Nityanand S.

Int J Lab Hematol. 2018 Apr;40(2):144-151. doi: 10.1111/ijlh.12754. Epub 2017 Oct 6.


Psoriasis: a mixed autoimmune and autoinflammatory disease.

Liang Y, Sarkar MK, Tsoi LC, Gudjonsson JE.

Curr Opin Immunol. 2017 Dec;49:1-8. doi: 10.1016/j.coi.2017.07.007. Epub 2017 Jul 22. Review.


Use of chimeric type IV secretion systems to define contributions of outer membrane subassemblies for contact-dependent translocation.

Gordon JE, Costa TRD, Patel RS, Gonzalez-Rivera C, Sarkar MK, Orlova EV, Waksman G, Christie PJ.

Mol Microbiol. 2017 Jul;105(2):273-293. doi: 10.1111/mmi.13700. Epub 2017 May 18.


The Molecular Revolution in Cutaneous Biology: The Era of Global Transcriptional Analysis.

Johnston A, Sarkar MK, Vrana A, Tsoi LC, Gudjonsson JE.

J Invest Dermatol. 2017 May;137(5):e87-e91. doi: 10.1016/j.jid.2016.02.817. Review.


Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis.

Swindell WR, Michaels KA, Sutter AJ, Diaconu D, Fritz Y, Xing X, Sarkar MK, Liang Y, Tsoi A, Gudjonsson JE, Ward NL.

Genome Med. 2017 Mar 9;9(1):24. doi: 10.1186/s13073-017-0415-3.


Endogenous Glucocorticoid Deficiency in Psoriasis Promotes Inflammation and Abnormal Differentiation.

Sarkar MK, Kaplan N, Tsoi LC, Xing X, Liang Y, Swindell WR, Hoover P, Aravind M, Baida G, Clark M, Voorhees JJ, Nair RP, Elder JT, Budunova I, Getsios S, Gudjonsson JE.

J Invest Dermatol. 2017 Jul;137(7):1474-1483. doi: 10.1016/j.jid.2017.02.972. Epub 2017 Mar 1. Erratum in: J Invest Dermatol. 2017 Dec;137(12):2665.


Mechanism of type-III protein secretion: Regulation of FlhA conformation by a functionally critical charged-residue cluster.

Erhardt M, Wheatley P, Kim EA, Hirano T, Zhang Y, Sarkar MK, Hughes KT, Blair DF.

Mol Microbiol. 2017 Apr;104(2):234-249. doi: 10.1111/mmi.13623. Epub 2017 Feb 28.


A gene network regulated by the transcription factor VGLL3 as a promoter of sex-biased autoimmune diseases.

Liang Y, Tsoi LC, Xing X, Beamer MA, Swindell WR, Sarkar MK, Berthier CC, Stuart PE, Harms PW, Nair RP, Elder JT, Voorhees JJ, Kahlenberg JM, Gudjonsson JE.

Nat Immunol. 2017 Feb;18(2):152-160. doi: 10.1038/ni.3643. Epub 2016 Dec 19.


Six-transmembrane epithelial antigens of the prostate comprise a novel inflammatory nexus in patients with pustular skin disorders.

Liang Y, Xing X, Beamer MA, Swindell WR, Sarkar MK, Roberts LW, Voorhees JJ, Kahlenberg JM, Harms PW, Johnston A, Gudjonsson JE.

J Allergy Clin Immunol. 2017 Apr;139(4):1217-1227. doi: 10.1016/j.jaci.2016.10.021. Epub 2016 Nov 21.


Lupus Skin Is Primed for IL-6 Inflammatory Responses through a Keratinocyte-Mediated Autocrine Type I Interferon Loop.

Stannard JN, Reed TJ, Myers E, Lowe L, Sarkar MK, Xing X, Gudjonsson JE, Kahlenberg JM.

J Invest Dermatol. 2017 Jan;137(1):115-122. doi: 10.1016/j.jid.2016.09.008. Epub 2016 Sep 16.


IL-17 Responses Are the Dominant Inflammatory Signal Linking Inverse, Erythrodermic, and Chronic Plaque Psoriasis.

Xing X, Liang Y, Sarkar MK, Wolterink L, Swindell WR, Voorhees JJ, Harms PW, Kahlenberg JM, Johnston A, Gudjonsson JE.

J Invest Dermatol. 2016 Dec;136(12):2498-2501. doi: 10.1016/j.jid.2016.07.008. Epub 2016 Jul 21. No abstract available.


Cross-Disease Transcriptomics: Unique IL-17A Signaling in Psoriasis Lesions and an Autoimmune PBMC Signature.

Swindell WR, Sarkar MK, Liang Y, Xing X, Gudjonsson JE.

J Invest Dermatol. 2016 Sep;136(9):1820-1830. doi: 10.1016/j.jid.2016.04.035. Epub 2016 May 17. Review.


An Xist-activating antisense RNA required for X-chromosome inactivation.

Sarkar MK, Gayen S, Kumar S, Maclary E, Buttigieg E, Hinten M, Kumari A, Harris C, Sado T, Kalantry S.

Nat Commun. 2015 Oct 19;6:8564. doi: 10.1038/ncomms9564.


Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance.

Swindell WR, Remmer HA, Sarkar MK, Xing X, Barnes DH, Wolterink L, Voorhees JJ, Nair RP, Johnston A, Elder JT, Gudjonsson JE.

Genome Med. 2015 Aug 4;7(1):86. doi: 10.1186/s13073-015-0208-5. eCollection 2015.


Psoriasis drug development and GWAS interpretation through in silico analysis of transcription factor binding sites.

Swindell WR, Sarkar MK, Stuart PE, Voorhees JJ, Elder JT, Johnston A, Gudjonsson JE.

Clin Transl Med. 2015 Mar 19;4:13. doi: 10.1186/s40169-015-0054-5. eCollection 2015.


Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin.

Tsoi LC, Iyer MK, Stuart PE, Swindell WR, Gudjonsson JE, Tejasvi T, Sarkar MK, Li B, Ding J, Voorhees JJ, Kang HM, Nair RP, Chinnaiyan AM, Abecasis GR, Elder JT.

Genome Biol. 2015 Jan 30;16:24. doi: 10.1186/s13059-014-0570-4.


Decalepisarayalpathra (J. Joseph & V. Chandras.) Venter, an endemic and endangered ethno medicinal plant from Western Ghats, India.

Verma SK, Sarkar MK.

Nat Prod Res. 2015;29(5):394-5. doi: 10.1080/14786419.2014.947498. Epub 2014 Aug 18.


Differentiation-dependent requirement of Tsix long non-coding RNA in imprinted X-chromosome inactivation.

Maclary E, Buttigieg E, Hinten M, Gayen S, Harris C, Sarkar MK, Purushothaman S, Kalantry S.

Nat Commun. 2014 Jun 30;5:4209. doi: 10.1038/ncomms5209.


Cellular dissection of psoriasis for transcriptome analyses and the post-GWAS era.

Swindell WR, Stuart PE, Sarkar MK, Voorhees JJ, Elder JT, Johnston A, Gudjonsson JE.

BMC Med Genomics. 2014 May 22;7:27. doi: 10.1186/1755-8794-7-27.


Receptor variation and susceptibility to Middle East respiratory syndrome coronavirus infection.

Barlan A, Zhao J, Sarkar MK, Li K, McCray PB Jr, Perlman S, Gallagher T.

J Virol. 2014 May;88(9):4953-61. doi: 10.1128/JVI.00161-14. Epub 2014 Feb 19.


DNA substrate-induced activation of the Agrobacterium VirB/VirD4 type IV secretion system.

Cascales E, Atmakuri K, Sarkar MK, Christie PJ.

J Bacteriol. 2013 Jun;195(11):2691-704. doi: 10.1128/JB.00114-13. Epub 2013 Apr 5.


Isolation of bacterial type IV machine subassemblies.

Sarkar MK, Husnain SI, Jakubowski SJ, Christie PJ.

Methods Mol Biol. 2013;966:187-204. doi: 10.1007/978-1-62703-245-2_12.


Efficacy and safety of magnesium sulphate (MgSO4) in the treatment of eclampsia.

Alauddin M, Sarkar MK, Munshi S, Tapan N, Maltrayee SM.

J Indian Med Assoc. 2011 Jul;109(7):485-6, 488.


Prevention of tertiary butyl hydroperoxide induced oxidative impairment and cell death by a novel antioxidant protein molecule isolated from the herb, Phyllanthus niruri.

Sarkar MK, Sil PC.

Toxicol In Vitro. 2010 Sep;24(6):1711-9. doi: 10.1016/j.tiv.2010.05.014. Epub 2010 May 25.


Chemotaxis signaling protein CheY binds to the rotor protein FliN to control the direction of flagellar rotation in Escherichia coli.

Sarkar MK, Paul K, Blair D.

Proc Natl Acad Sci U S A. 2010 May 18;107(20):9370-5. doi: 10.1073/pnas.1000935107. Epub 2010 May 3.


Subunit organization and reversal-associated movements in the flagellar switch of Escherichia coli.

Sarkar MK, Paul K, Blair DF.

J Biol Chem. 2010 Jan 1;285(1):675-84. doi: 10.1074/jbc.M109.068676. Epub 2009 Oct 26.


Rathke's cleft cyst: missed etiology of panhypopituitarism in presence of coexistent ocular and neurocysticercosis.

Bakhshi S, Kalpatthi R, Sharma R, Sarkar MK, Menon PS.

J Pediatr Endocrinol Metab. 2004 Aug;17(8):1133-6.


Inhibition of carrageenin-induced pedal oedema in rats by immobilisation stress.

Bhattacharya SK, Das N, Sarkar MK.

Res Exp Med (Berl). 1987;187(4):303-13.


Effect of lycoriside, an acylglucosyloxy alkaloid, on mast cells.

Ghosal S, Shanthy A, Mukhopadhyay M, Sarkar MK, Das PK.

Pharm Res. 1986 Aug;3(4):240-3. doi: 10.1023/A:1016346931894.


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