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Pentafluorophenyl Substitution of Natural Di(indol-3-yl)methane Strongly Enhances Growth Inhibition and Apoptosis Induction in Various Cancer Cell Lines.

Ahmad A, Dandawate P, Schruefer S, Padhye S, Sarkar FH, Schobert R, Biersack B.

Chem Biodivers. 2019 Apr;16(4):e1900028. doi: 10.1002/cbdv.201900028. Epub 2019 Mar 19.


A new promising way of maintenance therapy in advanced ovarian cancer: a comparative clinical study.

Kiselev VI, Ashrafyan LA, Muyzhnek EL, Gerfanova EV, Antonova IB, Aleshikova OI, Sarkar FH.

BMC Cancer. 2018 Sep 20;18(1):904. doi: 10.1186/s12885-018-4792-9.


Correction to: The versatile role of exosomes in cancer progression: diagnostic and therapeutic implications.

Sundararajan V, Sarkar FH, Ramasamy TS.

Cell Oncol (Dordr). 2018 Aug;41(4):463. doi: 10.1007/s13402-018-0396-2.


The multifaceted role of exosomes in cancer progression: diagnostic and therapeutic implications [corrected].

Sundararajan V, Sarkar FH, Ramasamy TS.

Cell Oncol (Dordr). 2018 Jun;41(3):223-252. doi: 10.1007/s13402-018-0378-4. Epub 2018 Apr 17. Review. Erratum in: Cell Oncol (Dordr). 2018 Aug;41(4):463.


Retraction notice to: Sensitization of squamous cell carcinoma to cisplatin induced killing by natural agents.

Ali S, Varghese L, Pereira L, Tulunay-Ugur OE, Kucuk O, Carey TE, Wolf GT, Sarkar FH.

Cancer Lett. 2018 Jun 1;423:154. doi: 10.1016/j.canlet.2018.03.018.


Retraction notice to "Notch-1 induces Epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells".

Bao B, Wang Z, Ali S, Kong D, Li Y, Ahmad A, Banerjee S, Azmi AS, Miele L, Sarkar FH.

Cancer Lett. 2018 Jun 1;423:153. doi: 10.1016/j.canlet.2018.03.020.


Stem Cells Derived from Amniotic Fluid: A Potential Pluripotent-Like Cell Source for Cellular Therapy?

Ramasamy TS, Velaithan V, Yeow Y, Sarkar FH.

Curr Stem Cell Res Ther. 2018;13(4):252-264. doi: 10.2174/1574888X13666180115093800. Review.


Retraction notice to "Increased Ras GTPase activity is regulated by miRNAs that can be attenuated by CDF treatment in pancreatic cancer cells" [Cancer Lett. 319(2) (2012) 173-181].

Ali S, Ahmad A, Aboukameel A, Bao B, Padhye S, Philip PA, Sarkar FH.

Cancer Lett. 2018 Feb 1;414:313. doi: 10.1016/j.canlet.2017.11.030. No abstract available.


Folic acid conjugated polymeric micelles loaded with a curcumin difluorinated analog for targeting cervical and ovarian cancers.

Luong D, Kesharwani P, Alsaab HO, Sau S, Padhye S, Sarkar FH, Iyer AK.

Colloids Surf B Biointerfaces. 2017 Sep 1;157:490-502. doi: 10.1016/j.colsurfb.2017.06.025. Epub 2017 Jun 21.


Synthesis and characterization of folate decorated albumin bio-conjugate nanoparticles loaded with a synthetic curcumin difluorinated analogue.

Gawde KA, Kesharwani P, Sau S, Sarkar FH, Padhye S, Kashaw SK, Iyer AK.

J Colloid Interface Sci. 2017 Jun 15;496:290-299. doi: 10.1016/j.jcis.2017.01.092. Epub 2017 Feb 14.


Improved anticancer and antiparasitic activity of new lawsone Mannich bases.

Mahal K, Ahmad A, Schmitt F, Lockhauserbäumer J, Starz K, Pradhan R, Padhye S, Sarkar FH, Koko WS, Schobert R, Ersfeld K, Biersack B.

Eur J Med Chem. 2017 Jan 27;126:421-431. doi: 10.1016/j.ejmech.2016.11.043. Epub 2016 Nov 22.


A Study of The Effects of Novel Rhenium Compounds on Pancreatic and Prostate Cancer Cell Lines.

Banerjee HN, Boston A, Barfield A, Stevenson M, Sarkar FH, Giri D, Winstead A, Krause JA, Mandal SK.

Int J Sci Res (Ahmedabad). 2016 Jul;5(7). pii: 10501. No abstract available.


Solubility enhancement and targeted delivery of a potent anticancer flavonoid analogue to cancer cells using ligand decorated dendrimer nano-architectures.

Luong D, Kesharwani P, Killinger BA, Moszczynska A, Sarkar FH, Padhye S, Rishi AK, Iyer AK.

J Colloid Interface Sci. 2016 Dec 15;484:33-43. doi: 10.1016/j.jcis.2016.08.061. Epub 2016 Aug 24.


Retraction Note to: FoxM1 down-regulation leads to inhibition of proliferation, migration and invasion of breast cancer cells through the modulation of extra-cellular matrix degrading factors.

Ahmad A, Wang Z, Kong D, Ali S, Li Y, Banerjee S, Ali R, Sarkar FH.

Breast Cancer Res Treat. 2016 Aug;158(3):607. No abstract available.


Retraction Note to: Platelet-derived growth factor-D contributes to aggressiveness of breast cancer cells by up-regulating Notch and NF-κB signaling pathways.

Ahmad A, Wang Z, Kong D, Ali R, Ali S, Banerjee S, Sarkar FH.

Breast Cancer Res Treat. 2016 Aug;158(3):605. No abstract available.


Anti-androgenic activity of absorption-enhanced 3, 3'-diindolylmethane in prostatectomy patients.

Hwang C, Sethi S, Heilbrun LK, Gupta NS, Chitale DA, Sakr WA, Menon M, Peabody JO, Smith DW, Sarkar FH, Heath EI.

Am J Transl Res. 2016 Jan 15;8(1):166-76. eCollection 2016.


MicroRNA Targeted Therapeutic Approach for Pancreatic Cancer.

Li Y, Sarkar FH.

Int J Biol Sci. 2016 Jan 28;12(3):326-37. doi: 10.7150/ijbs.15017. eCollection 2016. Review.


Comparative Analysis of Differentially Expressed miRNAs and their Downstream mRNAs in Ovarian Cancer and its Associated Endometriosis.

Wu RL, Ali S, Bandyopadhyay S, Alosh B, Hayek K, Daaboul MF, Winer I, Sarkar FH, Ali-Fehmi R.

J Cancer Sci Ther. 2015;7(7):258-265.


Differential Expression of MicroRNAs in Tissues and Plasma Co-exists as a Biomarker for Pancreatic Cancer.

Ali S, Dubaybo H, Brand RE, Sarkar FH.

J Cancer Sci Ther. 2015;7(11):336-346.


Identification of Differentially Expressed miRNAs in Appendiceal Mucinous Cystadenocarcinoma from Mucinous Cystadenoma.

Wu RL, Ali S, Sarkar FH, Beydoun R.

J Cancer Sci Ther. 2015 Nov;7(11):328-335. Epub 2015 Nov 24.


The bounty of nature for changing the cancer landscape.

Ahmad A, Li Y, Sarkar FH.

Mol Nutr Food Res. 2016 Jun;60(6):1251-63. doi: 10.1002/mnfr.201500867. Epub 2016 Feb 16. Review.


The Role of Cancer Stem Cells in Recurrent and Drug-Resistant Lung Cancer.

Suresh R, Ali S, Ahmad A, Philip PA, Sarkar FH.

Adv Exp Med Biol. 2016;890:57-74. doi: 10.1007/978-3-319-24932-2_4. Review.


ASPP and iASPP: Implication in cancer development and progression.

Li Y, Ahmad A, Sarkar FH.

Cell Mol Biol (Noisy-le-grand). 2015 Oct 30;61(6):2-8. Review.


Role of BioResponse 3,3'-Diindolylmethane in the Treatment of Human Prostate Cancer: Clinical Experience.

Li Y, Sarkar FH.

Med Princ Pract. 2016;25 Suppl 2:11-7. doi: 10.1159/000439307. Epub 2015 Oct 27. Review.


Hyaluronic acid-conjugated polyamidoamine dendrimers for targeted delivery of 3,4-difluorobenzylidene curcumin to CD44 overexpressing pancreatic cancer cells.

Kesharwani P, Xie L, Banerjee S, Mao G, Padhye S, Sarkar FH, Iyer AK.

Colloids Surf B Biointerfaces. 2015 Dec 1;136:413-23. doi: 10.1016/j.colsurfb.2015.09.043. Epub 2015 Sep 28.


The biological complexity of RKIP signaling in human cancers.

Farooqi AA, Li Y, Sarkar FH.

Exp Mol Med. 2015 Sep 25;47:e185. doi: 10.1038/emm.2015.70. Review.


Differential Expression of MicroRNAs in Papillary Thyroid Carcinoma and Their Role in Racial Disparity.

Suresh R, Sethi S, Ali S, Giorgadze T, Sarkar FH.

J Cancer Sci Ther. 2015 May;7(5):145-154.


Role of JNK and NF-κB in mediating the effect of combretastatin A-4 and brimamin on endothelial and carcinoma cells.

Mahal K, Ahmad A, Sethi S, Resch M, Ficner R, Sarkar FH, Schobert R, Biersack B.

Cell Oncol (Dordr). 2015 Dec;38(6):463-78. doi: 10.1007/s13402-015-0243-7. Epub 2015 Sep 10.


Whole genome sequence analysis links chromothripsis to EGFR, MDM2, MDM4, and CDK4 amplification in glioblastoma.

Furgason JM, Koncar RF, Michelhaugh SK, Sarkar FH, Mittal S, Sloan AE, Barnholtz-Sloan JS, Bahassi el M.

Oncoscience. 2015 Jul 31;2(7):618-28. eCollection 2015.


Hyaluronic Acid Engineered Nanomicelles Loaded with 3,4-Difluorobenzylidene Curcumin for Targeted Killing of CD44+ Stem-Like Pancreatic Cancer Cells.

Kesharwani P, Banerjee S, Padhye S, Sarkar FH, Iyer AK.

Biomacromolecules. 2015 Sep 14;16(9):3042-53. doi: 10.1021/acs.biomac.5b00941. Epub 2015 Aug 31.


Novel Holistic Approaches for Overcoming Therapy Resistance in Pancreatic and Colon Cancers.

Sarkar FH.

Med Princ Pract. 2016;25 Suppl 2:3-10. doi: 10.1159/000435814. Epub 2015 Jul 24. Review.


Functional role of miR-10b in tamoxifen resistance of ER-positive breast cancer cells through down-regulation of HDAC4.

Ahmad A, Ginnebaugh KR, Yin S, Bollig-Fischer A, Reddy KB, Sarkar FH.

BMC Cancer. 2015 Jul 24;15:540. doi: 10.1186/s12885-015-1561-x.


Development of patient-derived xenograft models from a spontaneously immortal low-grade meningioma cell line, KCI-MENG1.

Michelhaugh SK, Guastella AR, Varadarajan K, Klinger NV, Parajuli P, Ahmad A, Sethi S, Aboukameel A, Kiousis S, Zitron IM, Ebrahim SA, Polin LA, Sarkar FH, Bollig-Fischer A, Mittal S.

J Transl Med. 2015 Jul 15;13:227. doi: 10.1186/s12967-015-0596-8.


Liposome encapsulated curcumin-difluorinated (CDF) inhibits the growth of cisplatin resistant head and neck cancer stem cells.

Basak SK, Zinabadi A, Wu AW, Venkatesan N, Duarte VM, Kang JJ, Dalgard CL, Srivastava M, Sarkar FH, Wang MB, Srivatsan ES.

Oncotarget. 2015 Jul 30;6(21):18504-17.


Contribution of microRNAs in understanding the pancreatic tumor microenvironment involving cancer associated stellate and fibroblast cells.

Ali S, Suresh R, Banerjee S, Bao B, Xu Z, Wilson J, Philip PA, Apte M, Sarkar FH.

Am J Cancer Res. 2015 Feb 15;5(3):1251-64. eCollection 2015.


Parenterally administrable nano-micelles of 3,4-difluorobenzylidene curcumin for treating pancreatic cancer.

Kesharwani P, Banerjee S, Padhye S, Sarkar FH, Iyer AK.

Colloids Surf B Biointerfaces. 2015 Aug 1;132:138-45. doi: 10.1016/j.colsurfb.2015.05.007. Epub 2015 May 14.


Molecular docking and inhibition of matrix metalloproteinase-2 by novel difluorinatedbenzylidene curcumin analog.

Ahmad A, Sayed A, Ginnebaugh KR, Sharma V, Suri A, Saraph A, Padhye S, Sarkar FH.

Am J Transl Res. 2015 Feb 15;7(2):298-308. eCollection 2015.


miR-20b is up-regulated in brain metastases from primary breast cancers.

Ahmad A, Ginnebaugh KR, Sethi S, Chen W, Ali R, Mittal S, Sarkar FH.

Oncotarget. 2015 May 20;6(14):12188-95.


Overview on the complexity of androgen receptor-targeted therapy for prostate cancer.

Farooqi AA, Sarkar FH.

Cancer Cell Int. 2015 Feb 4;15:7. doi: 10.1186/s12935-014-0153-1. eCollection 2015.


Molecular targets of naturopathy in cancer research: bridge to modern medicine.

Ahmad A, Ginnebaugh KR, Li Y, Padhye SB, Sarkar FH.

Nutrients. 2015 Jan 6;7(1):321-34. doi: 10.3390/nu7010321. Review.


The Role of Nutraceuticals in Pancreatic Cancer Prevention and Therapy: Targeting Cellular Signaling, MicroRNAs, and Epigenome.

Li Y, Go VL, Sarkar FH.

Pancreas. 2015 Jan;44(1):1-10. doi: 10.1097/MPA.0000000000000257. Review.


Erratum to: Comparative in vivo evaluations of curcumin and its analog difluorinated curcumin against cisplatin-induced nephrotoxicity.

Sahin K, Orhan C, Tuzcu M, Muqbil I, Sahin N, Gencoglu H, Guler O, Padhye SB, Sarkar FH, Mohammad RM.

Biol Trace Elem Res. 2015 Mar;164(1):162-3. doi: 10.1007/s12011-014-0198-y. No abstract available.


Pharmacological Intervention through Dietary Nutraceuticals in Gastrointestinal Neoplasia.

Ullah MF, Bhat SH, Husain E, Abu-Duhier F, Hadi SM, Sarkar FH, Ahmad A.

Crit Rev Food Sci Nutr. 2016 Jul 3;56(9):1501-18. doi: 10.1080/10408398.2013.772091. Review.


Metformin may function as anti-cancer agent via targeting cancer stem cells: the potential biological significance of tumor-associated miRNAs in breast and pancreatic cancers.

Bao B, Azmi AS, Ali S, Zaiem F, Sarkar FH.

Ann Transl Med. 2014 Jun;2(6):59. doi: 10.3978/j.issn.2305-5839.2014.06.05. Review.


Androgen receptor splice variants contribute to prostate cancer aggressiveness through induction of EMT and expression of stem cell marker genes.

Kong D, Sethi S, Li Y, Chen W, Sakr WA, Heath E, Sarkar FH.

Prostate. 2015 Feb;75(2):161-74. doi: 10.1002/pros.22901. Epub 2014 Oct 13.


Up-regulation of microRNA-10b is associated with the development of breast cancer brain metastasis.

Ahmad A, Sethi S, Chen W, Ali-Fehmi R, Mittal S, Sarkar FH.

Am J Transl Res. 2014 Jul 18;6(4):384-90. eCollection 2014.


Deregulation of miR-146a expression in a mouse model of pancreatic cancer affecting EGFR signaling.

Ali S, Ahmad A, Aboukameel A, Ahmed A, Bao B, Banerjee S, Philip PA, Sarkar FH.

Cancer Lett. 2014 Aug 28;351(1):134-42. doi: 10.1016/j.canlet.2014.05.013. Epub 2014 May 16.


The therapeutic potential of targeting the epithelial-mesenchymal transition in cancer.

Ginnebaugh KR, Ahmad A, Sarkar FH.

Expert Opin Ther Targets. 2014 Jul;18(7):731-45. doi: 10.1517/14728222.2014.909807. Epub 2014 Apr 23. Review.


Differentially expressed miRNAs in cancer-stem-like cells: markers for tumor cell aggressiveness of pancreatic cancer.

Bao B, Ali S, Ahmad A, Li Y, Banerjee S, Kong D, Aboukameel A, Mohammad R, Van Buren E, Azmi AS, Sarkar FH.

Stem Cells Dev. 2014 Aug 15;23(16):1947-58. doi: 10.1089/scd.2013.0551. Epub 2014 Jun 6.


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