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Items: 28

1.

UbE2E1/UBCH6 Is a Critical in Vivo E2 for the PRC1-catalyzed Ubiquitination of H2A at Lys-119.

Wheaton K, Sarkari F, Stanly Johns B, Davarinejad H, Egorova O, Kaustov L, Raught B, Saridakis V, Sheng Y.

J Biol Chem. 2017 Feb 17;292(7):2893-2902. doi: 10.1074/jbc.M116.749564. Epub 2017 Jan 10.

2.

A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein.

Smirnova E, Kwan JJ, Siu R, Gao X, Zoidl G, Demeler B, Saridakis V, Donaldson LW.

Cell Commun Signal. 2016 Aug 22;14(1):17. doi: 10.1186/s12964-016-0140-3.

3.

Identification of Kaposi Sarcoma Herpesvirus (KSHV) vIRF1 Protein as a Novel Interaction Partner of Human Deubiquitinase USP7.

Chavoshi S, Egorova O, Lacdao IK, Farhadi S, Sheng Y, Saridakis V.

J Biol Chem. 2016 Mar 18;291(12):6281-91. doi: 10.1074/jbc.M115.710632. Epub 2016 Jan 19.

4.

Nicotinamide mononucleotide adenylyltransferase displays alternate binding modes for nicotinamide nucleotides.

Pfoh R, Pai EF, Saridakis V.

Acta Crystallogr D Biol Crystallogr. 2015 Oct;71(Pt 10):2032-9. doi: 10.1107/S1399004715015497. Epub 2015 Sep 26.

5.

Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7.

Pfoh R, Lacdao IK, Georges AA, Capar A, Zheng H, Frappier L, Saridakis V.

PLoS Pathog. 2015 Jun 5;11(6):e1004950. doi: 10.1371/journal.ppat.1004950. eCollection 2015 Jun.

6.

Functional analyses of polymorphic variants of human terminal deoxynucleotidyl transferase.

Troshchynsky A, Dzneladze I, Chen L, Sheng Y, Saridakis V, Wu GE.

Genes Immun. 2015 Sep;16(6):388-98. doi: 10.1038/gene.2015.19. Epub 2015 Jun 4.

PMID:
26043173
7.

Deubiquitinases and the new therapeutic opportunities offered to cancer.

Pfoh R, Lacdao IK, Saridakis V.

Endocr Relat Cancer. 2015 Feb;22(1):T35-54. doi: 10.1530/ERC-14-0516. Review.

8.

A role for USP7 in DNA replication.

Jagannathan M, Nguyen T, Gallo D, Luthra N, Brown GW, Saridakis V, Frappier L.

Mol Cell Biol. 2014 Jan;34(1):132-45. doi: 10.1128/MCB.00639-13. Epub 2013 Nov 4.

9.

Ubiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1.

Sarkari F, Wheaton K, La Delfa A, Mohamed M, Shaikh F, Khatun R, Arrowsmith CH, Frappier L, Saridakis V, Sheng Y.

J Biol Chem. 2013 Jun 7;288(23):16975-85. doi: 10.1074/jbc.M113.469262. Epub 2013 Apr 19.

10.

Toll-like receptors gene polymorphisms may confer increased susceptibility to breast cancer development.

Theodoropoulos GE, Saridakis V, Karantanos T, Michalopoulos NV, Zagouri F, Kontogianni P, Lymperi M, Gazouli M, Zografos GC.

Breast. 2012 Aug;21(4):534-8. doi: 10.1016/j.breast.2012.04.001. Epub 2012 May 2.

11.

Structural and functional comparison of the RING domains of two p53 E3 ligases, Mdm2 and Pirh2.

Shloush J, Vlassov JE, Engson I, Duan S, Saridakis V, Dhe-Paganon S, Raught B, Sheng Y, Arrowsmith CH.

J Biol Chem. 2011 Feb 11;286(6):4796-808. doi: 10.1074/jbc.M110.157669. Epub 2010 Nov 17.

12.

Further insight into substrate recognition by USP7: structural and biochemical analysis of the HdmX and Hdm2 interactions with USP7.

Sarkari F, La Delfa A, Arrowsmith CH, Frappier L, Sheng Y, Saridakis V.

J Mol Biol. 2010 Oct 8;402(5):825-37. doi: 10.1016/j.jmb.2010.08.017. Epub 2010 Aug 14.

PMID:
20713061
13.

Patients' perception of quality of pre-operative informed consent in athens, Greece: a pilot study.

Falagas ME, Akrivos PD, Alexiou VG, Saridakis V, Moutos T, Peppas G, Kondilis BK.

PLoS One. 2009 Nov 26;4(11):e8073. doi: 10.1371/journal.pone.0008073.

14.

Does the use of probiotics/synbiotics prevent postoperative infections in patients undergoing abdominal surgery? A meta-analysis of randomized controlled trials.

Pitsouni E, Alexiou V, Saridakis V, Peppas G, Falagas ME.

Eur J Clin Pharmacol. 2009 Jun;65(6):561-70. doi: 10.1007/s00228-009-0642-7. Epub 2009 Mar 27.

PMID:
19326107
15.

The hydrophobic motif of ROCK2 requires association with the N-terminal extension for kinase activity.

Couzens AL, Saridakis V, Scheid MP.

Biochem J. 2009 Apr 1;419(1):141-8. doi: 10.1042/BJ20081376.

PMID:
19099536
16.

Structural insight on the mechanism of regulation of the MarR family of proteins: high-resolution crystal structure of a transcriptional repressor from Methanobacterium thermoautotrophicum.

Saridakis V, Shahinas D, Xu X, Christendat D.

J Mol Biol. 2008 Mar 28;377(3):655-67. doi: 10.1016/j.jmb.2008.01.001. Epub 2008 Jan 11.

PMID:
18272181
17.

Molecular recognition of p53 and MDM2 by USP7/HAUSP.

Sheng Y, Saridakis V, Sarkari F, Duan S, Wu T, Arrowsmith CH, Frappier L.

Nat Struct Mol Biol. 2006 Mar;13(3):285-91. Epub 2006 Feb 12.

PMID:
16474402
18.

Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization.

Saridakis V, Sheng Y, Sarkari F, Holowaty MN, Shire K, Nguyen T, Zhang RG, Liao J, Lee W, Edwards AM, Arrowsmith CH, Frappier L.

Mol Cell. 2005 Apr 1;18(1):25-36.

19.

The structural basis for methylmalonic aciduria. The crystal structure of archaeal ATP:cobalamin adenosyltransferase.

Saridakis V, Yakunin A, Xu X, Anandakumar P, Pennycooke M, Gu J, Cheung F, Lew JM, Sanishvili R, Joachimiak A, Arrowsmith CH, Christendat D, Edwards AM.

J Biol Chem. 2004 May 28;279(22):23646-53. Epub 2004 Mar 25.

20.

Structural and functional analysis of a truncated form of Saccharomyces cerevisiae ATP sulfurylase: C-terminal domain essential for oligomer formation but not for activity.

Lalor DJ, Schnyder T, Saridakis V, Pilloff DE, Dong A, Tang H, Leyh TS, Pai EF.

Protein Eng. 2003 Dec;16(12):1071-9.

PMID:
14983089
21.

Crystal structure of chorismate synthase from Aquifex aeolicus reveals a novel beta alpha beta sandwich topology.

Viola CM, Saridakis V, Christendat D.

Proteins. 2004 Jan 1;54(1):166-9. No abstract available.

PMID:
14705034
23.

The crystal structure of hypothetical protein MTH1491 from Methanobacterium thermoautotrophicum.

Christendat D, Saridakis V, Kim Y, Kumar PA, Xu X, Semesi A, Joachimiak A, Arrowsmith CH, Edwards AM.

Protein Sci. 2002 Jun;11(6):1409-14.

24.

Crystal structure of Methanobacterium thermoautotrophicum conserved protein MTH1020 reveals an NTN-hydrolase fold.

Saridakis V, Christendat D, Thygesen A, Arrowsmith CH, Edwards AM, Pai EF.

Proteins. 2002 Jul 1;48(1):141-3. No abstract available.

PMID:
12012346
25.

Insights into ligand binding and catalysis of a central step in NAD+ synthesis: structures of Methanobacterium thermoautotrophicum NMN adenylyltransferase complexes.

Saridakis V, Christendat D, Kimber MS, Dharamsi A, Edwards AM, Pai EF.

J Biol Chem. 2001 Mar 9;276(10):7225-32. Epub 2000 Nov 3.

26.

Structural proteomics of an archaeon.

Christendat D, Yee A, Dharamsi A, Kluger Y, Savchenko A, Cort JR, Booth V, Mackereth CD, Saridakis V, Ekiel I, Kozlov G, Maxwell KL, Wu N, McIntosh LP, Gehring K, Kennedy MA, Davidson AR, Pai EF, Gerstein M, Edwards AM, Arrowsmith CH.

Nat Struct Biol. 2000 Oct;7(10):903-9.

PMID:
11017201
27.

Crystal structure of dTDP-4-keto-6-deoxy-D-hexulose 3,5-epimerase from Methanobacterium thermoautotrophicum complexed with dTDP.

Christendat D, Saridakis V, Dharamsi A, Bochkarev A, Pai EF, Arrowsmith CH, Edwards AM.

J Biol Chem. 2000 Aug 11;275(32):24608-12.

28.

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