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Items: 25


Assessing Canonical and Adaptive Natural Killer Cell Function in Suppression Assays In Vitro.

Sarhan D, Miller JS.

Methods Mol Biol. 2019;1913:153-166. doi: 10.1007/978-1-4939-8979-9_11.


161533 TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS.

Sarhan D, Brandt L, Felices M, Guldevall K, Lenvik T, Hinderlie P, Curtsinger J, Warlick E, Spellman SR, Blazar BR, Weisdorf DJ, Cooley S, Vallera DA, Önfelt B, Miller JS.

Blood Adv. 2018 Jun 26;2(12):1459-1469. doi: 10.1182/bloodadvances.2017012369.


Adaptive NK Cells Resist Regulatory T-cell Suppression Driven by IL37.

Sarhan D, Hippen KL, Lemire A, Hying S, Luo X, Lenvik T, Curtsinger J, Davis Z, Zhang B, Cooley S, Cichocki F, Blazar BR, Miller JS.

Cancer Immunol Res. 2018 Jul;6(7):766-775. doi: 10.1158/2326-6066.CIR-17-0498. Epub 2018 May 21.


Early Reconstitution of NK and γδ T Cells and Its Implication for the Design of Post-Transplant Immunotherapy.

de Witte MA, Sarhan D, Davis Z, Felices M, Vallera DA, Hinderlie P, Curtsinger J, Cooley S, Wagner J, Kuball J, Miller JS.

Biol Blood Marrow Transplant. 2018 Jun;24(6):1152-1162. doi: 10.1016/j.bbmt.2018.02.023. Epub 2018 Mar 2.


Post-irradiation protective effects of ectoine on brain and testicles in male mice.

Refaat R, Sarhan D, Kotb M, El-Abd E, El-Bassiouni E.

Pharmacol Rep. 2018 Apr;70(2):304-308. doi: 10.1016/j.pharep.2017.10.002. Epub 2017 Oct 4.


Haploidentical natural killer cells induce remissions in non-Hodgkin lymphoma patients with low levels of immune-suppressor cells.

Bachanova V, Sarhan D, DeFor TE, Cooley S, Panoskaltsis-Mortari A, Blazar BR, Curtsinger JM, Burns L, Weisdorf DJ, Miller JS.

Cancer Immunol Immunother. 2018 Mar;67(3):483-494. doi: 10.1007/s00262-017-2100-1. Epub 2017 Dec 7.


Zoledronic acid inhibits NFAT and IL-2 signaling pathways in regulatory T cells and diminishes their suppressive function in patients with metastatic cancer.

Sarhan D, Leijonhufvud C, Murray S, Witt K, Seitz C, Wallerius M, Xie H, Ullén A, Harmenberg U, Lidbrink E, Rolny C, Andersson J, Lundqvist A.

Oncoimmunology. 2017 Jun 14;6(8):e1338238. doi: 10.1080/2162402X.2017.1338238. eCollection 2017.


GSK3 Inhibition Drives Maturation of NK Cells and Enhances Their Antitumor Activity.

Cichocki F, Valamehr B, Bjordahl R, Zhang B, Rezner B, Rogers P, Gaidarova S, Moreno S, Tuininga K, Dougherty P, McCullar V, Howard P, Sarhan D, Taras E, Schlums H, Abbot S, Shoemaker D, Bryceson YT, Blazar BR, Wolchko S, Cooley S, Miller JS.

Cancer Res. 2017 Oct 15;77(20):5664-5675. doi: 10.1158/0008-5472.CAN-17-0799. Epub 2017 Aug 8.


Enhanced stimulation of human tumor-specific T cells by dendritic cells matured in the presence of interferon-γ and multiple toll-like receptor agonists.

Lövgren T, Sarhan D, Truxová I, Choudhary B, Maas R, Melief J, Nyström M, Edbäck U, Vermeij R, Scurti G, Nishimura M, Masucci G, Karlsson-Parra A, Lundqvist A, Adamson L, Kiessling R.

Cancer Immunol Immunother. 2017 Oct;66(10):1333-1344. doi: 10.1007/s00262-017-2029-4. Epub 2017 Jun 10.


Independent control of natural killer cell responsiveness and homeostasis at steady-state by CD11c+ dendritic cells.

Luu TT, Ganesan S, Wagner AK, Sarhan D, Meinke S, Garbi N, Hämmerling G, Alici E, Kärre K, Chambers BJ, Höglund P, Kadri N.

Sci Rep. 2016 Dec 1;6:37996. doi: 10.1038/srep37996.


Adaptive NK Cells with Low TIGIT Expression Are Inherently Resistant to Myeloid-Derived Suppressor Cells.

Sarhan D, Cichocki F, Zhang B, Yingst A, Spellman SR, Cooley S, Verneris MR, Blazar BR, Miller JS.

Cancer Res. 2016 Oct 1;76(19):5696-5706. Epub 2016 Aug 8.


Interleukin-10 -1082 G/A gene polymorphisms in Egyptian children with CAP: A case-control study.

Azab SF, Abdalhady MA, Elsaadany HF, Elkomi MA, Elhindawy EM, Sarhan DT, Salam MM, Allah MA, Emam AA, Noah MA, Abdelsalam NI, Abdellatif SH, Rass AA, Ismail SM, Gheith T, Aziz KA, Hamed ME, Abdelrahman HM, Ahmed AR, Nabil RM, Abdulmaksoud RS, Yousef HY.

Medicine (Baltimore). 2016 Jun;95(26):e4013. doi: 10.1097/MD.0000000000004013.


Serum and CSF adiponectin, leptin, and interleukin 6 levels as adipocytokines in Egyptian children with febrile seizures: a cross-sectional study.

Azab SF, Abdalhady MA, Almalky MA, Amin EK, Sarhan DT, Elhindawy EM, Allah MA, Elhewala AA, Salam MM, Hashem MI, Soliman AA, Akeel NE, Abdellatif SH, Elsamad NA, Rass AA, Arafat MS.

Ital J Pediatr. 2016 Apr 12;42:38. doi: 10.1186/s13052-016-0250-y.


Interleukin-6 gene polymorphisms in Egyptian children with febrile seizures: a case-control study.

Azab SF, Abdalhady MA, Ali A, Amin EK, Sarhan DT, Elhindawy EM, Almalky MA, Elhewala AA, Salam MM, Hashem MI, Soliman AA, Akeel NE, Abdellatif SH, Ismail SM, Elsamad NA, Arafat MS, Rass AA, Basset MA.

Ital J Pediatr. 2016 Mar 9;42:31. doi: 10.1186/s13052-016-0244-9.


Serum Hepcidin Levels in Childhood-Onset Ischemic Stroke: A Case-Control Study.

Azab SF, Akeel NE, Abdalhady MA, Elhewala AA, Ali AS, Amin EK, Sarhan DT, Almalky MA, Elhindawy EM, Salam MM, Soliman AA, Abdellatif SH, Ismail SM, Elsamad NA, Hashem MI, Aziz KA, Elazouni OM, Arafat MS.

Medicine (Baltimore). 2016 Mar;95(9):e2921. doi: 10.1097/MD.0000000000002921.


Natural Killer Cell-Based Therapies Targeting Cancer: Possible Strategies to Gain and Sustain Anti-Tumor Activity.

Dahlberg CI, Sarhan D, Chrobok M, Duru AD, Alici E.

Front Immunol. 2015 Nov 30;6:605. doi: 10.3389/fimmu.2015.00605. eCollection 2015. Review.


Dendritic cell regulation of NK-cell responses involves lymphotoxin-α, IL-12, and TGF-β.

Sarhan D, Palma M, Mao Y, Adamson L, Kiessling R, Mellstedt H, Österborg A, Lundqvist A.

Eur J Immunol. 2015 Jun;45(6):1783-93. doi: 10.1002/eji.201444885. Epub 2015 Apr 17.


Female Genital Dialogues: Female Genital Self-Image, Sexual Dysfunction, and Quality of Life in Patients With Vitiligo With and Without Genital Affection.

Sarhan D, Mohammed GF, Gomaa AH, Eyada MM.

J Sex Marital Ther. 2016;42(3):267-76. doi: 10.1080/0092623X.2015.1010678. Epub 2015 Feb 4.


Regulation of TRAIL-receptor expression by the ubiquitin-proteasome system.

Sarhan D, D'Arcy P, Lundqvist A.

Int J Mol Sci. 2014 Oct 14;15(10):18557-73. doi: 10.3390/ijms151018557. Review.


Inhibition of tumor-derived prostaglandin-e2 blocks the induction of myeloid-derived suppressor cells and recovers natural killer cell activity.

Mao Y, Sarhan D, Steven A, Seliger B, Kiessling R, Lundqvist A.

Clin Cancer Res. 2014 Aug 1;20(15):4096-106. doi: 10.1158/1078-0432.CCR-14-0635. Epub 2014 Jun 6.


A novel inhibitor of proteasome deubiquitinating activity renders tumor cells sensitive to TRAIL-mediated apoptosis by natural killer cells and T cells.

Sarhan D, Wennerberg E, D'Arcy P, Gurajada D, Linder S, Lundqvist A.

Cancer Immunol Immunother. 2013 Aug;62(8):1359-68. doi: 10.1007/s00262-013-1439-1. Epub 2013 May 21.


Doxorubicin sensitizes human tumor cells to NK cell- and T-cell-mediated killing by augmented TRAIL receptor signaling.

Wennerberg E, Sarhan D, Carlsten M, Kaminskyy VO, D'Arcy P, Zhivotovsky B, Childs R, Lundqvist A.

Int J Cancer. 2013 Oct 1;133(7):1643-52. doi: 10.1002/ijc.28163. Epub 2013 Apr 11.


Opposing consequences of signaling through EGF family members: Escape from CTLs could be a bait for NK cells.

Kiessling R, Okita R, Mougiakakos D, Mao Y, Sarhan D, Wennerberg E, Seliger B, Lundqvist A, Mimura K, Kono K.

Oncoimmunology. 2012 Oct 1;1(7):1200-1201.


Activated monocytes augment TRAIL-mediated cytotoxicity by human NK cells through release of IFN-γ.

Sarhan D, D'Arcy P, Wennerberg E, Lidén M, Hu J, Winqvist O, Rolny C, Lundqvist A.

Eur J Immunol. 2013 Jan;43(1):249-57. doi: 10.1002/eji.201242735. Epub 2012 Oct 26.


HER2/HER3 signaling regulates NK cell-mediated cytotoxicity via MHC class I chain-related molecule A and B expression in human breast cancer cell lines.

Okita R, Mougiakakos D, Ando T, Mao Y, Sarhan D, Wennerberg E, Seliger B, Lundqvist A, Mimura K, Kiessling R.

J Immunol. 2012 Mar 1;188(5):2136-45. doi: 10.4049/jimmunol.1102237. Epub 2012 Feb 1.

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