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Items: 1 to 50 of 352

1.

Using Lidar Technology To Assess Urban Air Pollution and Improve Estimates of Greenhouse Gas Emissions in Boston.

Barrera YD, Nehrkorn T, Hegarty J, Sargent M, Benmergui J, Gottlieb E, Wofsy SC, DeCola P, Hutyra L, Jones T.

Environ Sci Technol. 2019 Jul 2. doi: 10.1021/acs.est.9b00650. [Epub ahead of print]

PMID:
31265266
2.

Genome-wide analysis identifies rare copy number variations associated with inflammatory bowel disease.

Frenkel S, Bernstein CN, Sargent M, Kuang Q, Jiang W, Wei J, Thiruvahindrapuram B, Spriggs E, Scherer SW, Hu P.

PLoS One. 2019 Jun 11;14(6):e0217846. doi: 10.1371/journal.pone.0217846. eCollection 2019.

3.

Case reports: novel TUBG1 mutations with milder neurodevelopmental presentations.

Yuen YTK, Guella I, Roland E, Sargent M, Boelman C.

BMC Med Genet. 2019 May 31;20(1):95. doi: 10.1186/s12881-019-0827-6.

4.

Copy number variation-based gene set analysis reveals cytokine signalling pathways associated with psychiatric comorbidity in patients with inflammatory bowel disease.

Frenkel S, Bernstein CN, Sargent M, Jiang W, Kuang Q, Xu W, Hu P.

Genomics. 2019 May 7. pii: S0888-7543(19)30081-3. doi: 10.1016/j.ygeno.2019.05.001. [Epub ahead of print]

PMID:
31075388
5.

Congenital lactic acidosis, cerebral cysts and pulmonary hypertension in an infant with FOXRED1 related complex 1 deficiency.

Apatean D, Rakic B, Brunel-Guitton C, Hendson G, Bai R, Sargent MA, Lavoie PM, Patel M, Stockler-Ipsiroglu S.

Mol Genet Metab Rep. 2019 Apr 30;19:100472. doi: 10.1016/j.ymgmr.2019.100472. eCollection 2019 Jun.

6.

Disruption of valosin-containing protein activity causes cardiomyopathy and reveals pleiotropic functions in cardiac homeostasis.

Brody MJ, Vanhoutte D, Bakshi CV, Liu R, Correll RN, Sargent MA, Molkentin JD.

J Biol Chem. 2019 May 31;294(22):8918-8929. doi: 10.1074/jbc.RA119.007585. Epub 2019 Apr 21.

PMID:
31006653
7.

A randomized trial to reduce smoking among American Indians in South Dakota: The walking forward study.

Dignan MB, Jones K, Burhansstipanov L, Ahamed SI, Krebs LU, Williams D, Ahsan GMT, Addo I, Sargent M, Cina K, Crawford K, Thibeault D, Bordeaux S, Kanekar S, Petereit D.

Contemp Clin Trials. 2019 Jun;81:28-33. doi: 10.1016/j.cct.2019.04.007. Epub 2019 Apr 13.

8.

ERK1/2 signaling induces skeletal muscle slow fiber-type switching and reduces muscular dystrophy disease severity.

Boyer JG, Prasad V, Song T, Lee D, Fu X, Grimes KM, Sargent MA, Sadayappan S, Molkentin JD.

JCI Insight. 2019 Apr 9;5. pii: 127356. doi: 10.1172/jci.insight.127356.

9.

Congenital lactic acidosis, cerebral cysts and pulmonary hypertension in an infant with FOXRED1 related complex I deficiency.

Apatean D, Rakic B, Brunel-Guitton C, Hendson G, Bai R, Sargent MA, Lavoie PM, Patel M, Stockler-Ipsiroglu S.

Mol Genet Metab Rep. 2019 Jan 18;18:32-38. doi: 10.1016/j.ymgmr.2018.12.006. eCollection 2019 Mar.

10.

Lessons learned from inter-laboratory studies of carbon isotope analysis of honey.

Dunn PJH, Hill S, Cowen S, Goenaga-Infante H, Sargent M, Gören AC, Bilsel M, Şimşek A, Ogrinc N, Potočnik D, Armishaw P, Hai L, Konopelko L, Chubchenko Y, Chesson LA, van der Peijl G, Blaga C, Posey R, Camin F, Chernyshev A, Chowdhury SA.

Sci Justice. 2019 Jan;59(1):9-19. doi: 10.1016/j.scijus.2018.08.003. Epub 2018 Aug 16.

11.

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.

Schips TG, Vanhoutte D, Vo A, Correll RN, Brody MJ, Khalil H, Karch J, Tjondrokoesoemo A, Sargent MA, Maillet M, Ross RS, Molkentin JD.

Nat Commun. 2019 Jan 8;10(1):76. doi: 10.1038/s41467-018-08026-8.

12.

Living With Inflammatory Bowel Disease: Protocol for a Longitudinal Study of Factors Associated With Symptom Exacerbations.

Witges K, Targownik LE, Haviva C, Walker JR, Graff LA, Sexton KA, Lix L, Sargent M, Vagianos K, Bernstein CN.

JMIR Res Protoc. 2018 Nov 12;7(11):e11317. doi: 10.2196/11317.

13.

Cardiac Fibrosis in Proteotoxic Cardiac Disease is Dependent Upon Myofibroblast TGF -β Signaling.

Bhandary B, Meng Q, James J, Osinska H, Gulick J, Valiente-Alandi I, Sargent MA, Bhuiyan MS, Blaxall BC, Molkentin JD, Robbins J.

J Am Heart Assoc. 2018 Oct 16;7(20):e010013. doi: 10.1161/JAHA.118.010013.

14.

Single-Leg Spica Cast Application for Treatment of Pediatric Femoral Fracture.

Sargent MC.

JBJS Essent Surg Tech. 2017 Sep 13;7(3):e26. doi: 10.2106/JBJS.ST.15.00070. eCollection 2017 Sep 28.

15.

A Surprising Cause of Epilepsy: Whole Exome Sequencing in a Child With Focal Cortical Dysplasia Identifies Neurofibromatosis Type 2.

Muir KE, Sargent M, Boelman C.

Pediatr Neurol. 2018 Aug;85:79-81. doi: 10.1016/j.pediatrneurol.2018.05.006. Epub 2018 Jun 4. No abstract available.

PMID:
30122282
16.

ERK Signaling Controls Innate-like CD8+ T Cell Differentiation via the ELK4 (SAP-1) and ELK1 Transcription Factors.

Maurice D, Costello P, Sargent M, Treisman R.

J Immunol. 2018 Sep 15;201(6):1681-1691. doi: 10.4049/jimmunol.1800704. Epub 2018 Aug 1.

17.

Genetic Lineage Tracing of Sca-1+ Cells Reveals Endothelial but Not Myogenic Contribution to the Murine Heart.

Vagnozzi RJ, Sargent MA, Lin SJ, Palpant NJ, Murry CE, Molkentin JD.

Circulation. 2018 Dec 18;138(25):2931-2939. doi: 10.1161/CIRCULATIONAHA.118.035210. Erratum in: Circulation. 2018 Oct 9;138(15):e424.

PMID:
29991486
18.

Anthropogenic and biogenic CO2 fluxes in the Boston urban region.

Sargent M, Barrera Y, Nehrkorn T, Hutyra LR, Gately CK, Jones T, McKain K, Sweeney C, Hegarty J, Hardiman B, Wang JA, Wofsy SC.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):7491-7496. doi: 10.1073/pnas.1803715115. Epub 2018 Jul 2. Erratum in: Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9507.

19.

Defective Flux of Thrombospondin-4 through the Secretory Pathway Impairs Cardiomyocyte Membrane Stability and Causes Cardiomyopathy.

Brody MJ, Vanhoutte D, Schips TG, Boyer JG, Bakshi CV, Sargent MA, York AJ, Molkentin JD.

Mol Cell Biol. 2018 Jun 28;38(14). pii: e00114-18. doi: 10.1128/MCB.00114-18. Print 2018 Jul 15.

20.

Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart.

Fu X, Khalil H, Kanisicak O, Boyer JG, Vagnozzi RJ, Maliken BD, Sargent MA, Prasad V, Valiente-Alandi I, Blaxall BC, Molkentin JD.

J Clin Invest. 2018 May 1;128(5):2127-2143. doi: 10.1172/JCI98215. Epub 2018 Apr 16.

21.

Inhibiting Fibronectin Attenuates Fibrosis and Improves Cardiac Function in a Model of Heart Failure.

Valiente-Alandi I, Potter SJ, Salvador AM, Schafer AE, Schips T, Carrillo-Salinas F, Gibson AM, Nieman ML, Perkins C, Sargent MA, Huo J, Lorenz JN, DeFalco T, Molkentin JD, Alcaide P, Blaxall BC.

Circulation. 2018 Sep 18;138(12):1236-1252. doi: 10.1161/CIRCULATIONAHA.118.034609.

PMID:
29653926
22.

Autophagic cell death is dependent on lysosomal membrane permeability through Bax and Bak.

Karch J, Schips TG, Maliken BD, Brody MJ, Sargent MA, Kanisicak O, Molkentin JD.

Elife. 2017 Nov 17;6. pii: e30543. doi: 10.7554/eLife.30543.

23.

Pharmacological and Activated Fibroblast Targeting of Gβγ-GRK2 After Myocardial Ischemia Attenuates Heart Failure Progression.

Travers JG, Kamal FA, Valiente-Alandi I, Nieman ML, Sargent MA, Lorenz JN, Molkentin JD, Blaxall BC.

J Am Coll Cardiol. 2017 Aug 22;70(8):958-971. doi: 10.1016/j.jacc.2017.06.049.

24.

TGFBI functions similar to periostin but is uniquely dispensable during cardiac injury.

Schwanekamp JA, Lorts A, Sargent MA, York AJ, Grimes KM, Fischesser DM, Gokey JJ, Whitsett JA, Conway SJ, Molkentin JD.

PLoS One. 2017 Jul 27;12(7):e0181945. doi: 10.1371/journal.pone.0181945. eCollection 2017.

25.

Central adrenal insufficiency following traumatic brain injury: a missed diagnosis in the critically injured.

Fan E, Skippen PW, Sargent MA, Cochrane DD, Chanoine JP.

Childs Nerv Syst. 2017 Dec;33(12):2205-2207. doi: 10.1007/s00381-017-3536-5. Epub 2017 Jul 18.

PMID:
28721596
26.

Mitsugumin 29 regulates t-tubule architecture in the failing heart.

Correll RN, Lynch JM, Schips TG, Prasad V, York AJ, Sargent MA, Brochet DXP, Ma J, Molkentin JD.

Sci Rep. 2017 Jul 13;7(1):5328. doi: 10.1038/s41598-017-05284-2.

27.

Reality Versus Grant Application Research "Plans".

Burhansstipanov L, Krebs LU, Petereit D, Dignan MB, Ahamed SI, Sargent M, Cina K, Crawford K, Thibeault D, Bordeaux S, Kanekar S, Ahsan GMT, Williams D, Addo I.

Health Promot Pract. 2018 Jul;19(4):566-572. doi: 10.1177/1524839917700892. Epub 2017 Jul 2.

PMID:
28669241
28.

Caveolae-localized L-type Ca2+ channels do not contribute to function or hypertrophic signalling in the mouse heart.

Correll RN, Makarewich CA, Zhang H, Zhang C, Sargent MA, York AJ, Berretta RM, Chen X, Houser SR, Molkentin JD.

Cardiovasc Res. 2017 Jun 1;113(7):749-759. doi: 10.1093/cvr/cvx046.

29.

Fibroblast-Specific Genetic Manipulation of p38 Mitogen-Activated Protein Kinase In Vivo Reveals Its Central Regulatory Role in Fibrosis.

Molkentin JD, Bugg D, Ghearing N, Dorn LE, Kim P, Sargent MA, Gunaje J, Otsu K, Davis J.

Circulation. 2017 Aug 8;136(6):549-561. doi: 10.1161/CIRCULATIONAHA.116.026238. Epub 2017 Mar 29.

30.

Evidence of Bidirectional Associations Between Perceived Stress and Symptom Activity: A Prospective Longitudinal Investigation in Inflammatory Bowel Disease.

Sexton KA, Walker JR, Graff LA, Bernstein MT, Beatie B, Miller N, Sargent M, Targownik LE.

Inflamm Bowel Dis. 2017 Mar;23(3):473-483. doi: 10.1097/MIB.0000000000001040.

PMID:
28221251
31.

Nemo-Like Kinase (NLK) Is a Pathological Signaling Effector in the Mouse Heart.

Liu R, Khalil H, Lin SJ, Sargent MA, York AJ, Molkentin JD.

PLoS One. 2016 Oct 20;11(10):e0164897. doi: 10.1371/journal.pone.0164897. eCollection 2016.

32.

Thrombospondin expression in myofibers stabilizes muscle membranes.

Vanhoutte D, Schips TG, Kwong JQ, Davis J, Tjondrokoesoemo A, Brody MJ, Sargent MA, Kanisicak O, Yi H, Gao QQ, Rabinowitz JE, Volk T, McNally EM, Molkentin JD.

Elife. 2016 Sep 26;5. pii: e17589. doi: 10.7554/eLife.17589.

33.

Microbiome profiling of drinking water in relation to incidence of inflammatory bowel disease.

Forbes JD, Van Domselaar G, Sargent M, Green C, Springthorpe S, Krause DO, Bernstein CN.

Can J Microbiol. 2016 Sep;62(9):781-93. doi: 10.1139/cjm-2016-0219. Epub 2016 May 18.

PMID:
27420183
34.

Cathepsin S Contributes to the Pathogenesis of Muscular Dystrophy in Mice.

Tjondrokoesoemo A, Schips TG, Sargent MA, Vanhoutte D, Kanisicak O, Prasad V, Lin SC, Maillet M, Molkentin JD.

J Biol Chem. 2016 May 6;291(19):9920-8. doi: 10.1074/jbc.M116.719054. Epub 2016 Mar 10.

35.

A comparison of the gut microbiome between long-term users and non-users of proton pump inhibitors.

Clooney AG, Bernstein CN, Leslie WD, Vagianos K, Sargent M, Laserna-Mendieta EJ, Claesson MJ, Targownik LE.

Aliment Pharmacol Ther. 2016 May;43(9):974-84. doi: 10.1111/apt.13568. Epub 2016 Feb 29.

36.

Genetic overexpression of Serpina3n attenuates muscular dystrophy in mice.

Tjondrokoesoemo A, Schips T, Kanisicak O, Sargent MA, Molkentin JD.

Hum Mol Genet. 2016 Mar 15;25(6):1192-202. doi: 10.1093/hmg/ddw005. Epub 2016 Jan 6.

37.

Dissection of Thrombospondin-4 Domains Involved in Intracellular Adaptive Endoplasmic Reticulum Stress-Responsive Signaling.

Brody MJ, Schips TG, Vanhoutte D, Kanisicak O, Karch J, Maliken BD, Blair NS, Sargent MA, Prasad V, Molkentin JD.

Mol Cell Biol. 2015 Oct 12;36(1):2-12. doi: 10.1128/MCB.00607-15. Print 2016 Jan 1.

38.

Cardiac-specific deletion of protein phosphatase 1β promotes increased myofilament protein phosphorylation and contractile alterations.

Liu R, Correll RN, Davis J, Vagnozzi RJ, York AJ, Sargent MA, Nairn AC, Molkentin JD.

J Mol Cell Cardiol. 2015 Oct;87:204-13. doi: 10.1016/j.yjmcc.2015.08.018. Epub 2015 Aug 31.

39.

STIM1 elevation in the heart results in aberrant Ca²⁺ handling and cardiomyopathy.

Correll RN, Goonasekera SA, van Berlo JH, Burr AR, Accornero F, Zhang H, Makarewich CA, York AJ, Sargent MA, Chen X, Houser SR, Molkentin JD.

J Mol Cell Cardiol. 2015 Oct;87:38-47. doi: 10.1016/j.yjmcc.2015.07.032. Epub 2015 Aug 1.

40.

Treatment of Creatine Transporter (SLC6A8) Deficiency With Oral S-Adenosyl Methionine as Adjunct to L-arginine, Glycine, and Creatine Supplements.

Jaggumantri S, Dunbar M, Edgar V, Mignone C, Newlove T, Elango R, Collet JP, Sargent M, Stockler-Ipsiroglu S, van Karnebeek CD.

Pediatr Neurol. 2015 Oct;53(4):360-363.e2. doi: 10.1016/j.pediatrneurol.2015.05.006. Epub 2015 May 16.

PMID:
26205312
41.

The Mitochondrial Calcium Uniporter Selectively Matches Metabolic Output to Acute Contractile Stress in the Heart.

Kwong JQ, Lu X, Correll RN, Schwanekamp JA, Vagnozzi RJ, Sargent MA, York AJ, Zhang J, Bers DM, Molkentin JD.

Cell Rep. 2015 Jul 7;12(1):15-22. doi: 10.1016/j.celrep.2015.06.002. Epub 2015 Jun 25.

42.

The Relationship Among Perceived Stress, Symptoms, and Inflammation in Persons With Inflammatory Bowel Disease.

Targownik LE, Sexton KA, Bernstein MT, Beatie B, Sargent M, Walker JR, Graff LA.

Am J Gastroenterol. 2015 Jul;110(7):1001-12; quiz 1013. doi: 10.1038/ajg.2015.147. Epub 2015 Jun 16.

PMID:
26077178
43.

Necroptosis Interfaces with MOMP and the MPTP in Mediating Cell Death.

Karch J, Kanisicak O, Brody MJ, Sargent MA, Michael DM, Molkentin JD.

PLoS One. 2015 Jun 10;10(6):e0130520. doi: 10.1371/journal.pone.0130520. eCollection 2015.

44.

Genetic Analysis of Connective Tissue Growth Factor as an Effector of Transforming Growth Factor β Signaling and Cardiac Remodeling.

Accornero F, van Berlo JH, Correll RN, Elrod JW, Sargent MA, York A, Rabinowitz JE, Leask A, Molkentin JD.

Mol Cell Biol. 2015 Jun;35(12):2154-64. doi: 10.1128/MCB.00199-15. Epub 2015 Apr 13.

45.

Radiological prevalence of superior and posterior semicircular canal dehiscence in children.

Saxby AJ, Gowdy C, Fandiño M, Chadha NK, Kozak FK, Sargent MA, Lea J.

Int J Pediatr Otorhinolaryngol. 2015 Mar;79(3):411-8. doi: 10.1016/j.ijporl.2015.01.001. Epub 2015 Jan 14.

PMID:
25636666
46.

MRTF-SRF signaling is required for seeding of HSC/Ps in bone marrow during development.

Costello P, Sargent M, Maurice D, Esnault C, Foster K, Anjos-Afonso F, Treisman R.

Blood. 2015 Feb 19;125(8):1244-55. doi: 10.1182/blood-2014-08-595603. Epub 2015 Jan 8.

47.

Knowledge and screening of head and neck cancer among American Indians in South Dakota.

Dwojak S, Deschler D, Sargent M, Emerick K, Guadagnolo BA, Petereit D.

Am J Public Health. 2015 Jun;105(6):1155-60. doi: 10.2105/AJPH.2014.302177. Epub 2014 Oct 16.

48.

Treatment of X-linked creatine transporter (SLC6A8) deficiency: systematic review of the literature and three new cases.

Dunbar M, Jaggumantri S, Sargent M, Stockler-Ipsiroglu S, van Karnebeek CD.

Mol Genet Metab. 2014 Aug;112(4):259-74. doi: 10.1016/j.ymgme.2014.05.011. Epub 2014 May 29. Review.

PMID:
24953403
49.

Brain MRI abnormalities and spectrum of neurological and clinical findings in three patients with proximal 16p11.2 microduplication.

Filges I, Sparagana S, Sargent M, Selby K, Schlade-Bartusiak K, Lueder GT, Robichaux-Viehoever A, Schlaggar BL, Shimony JS, Shinawi M.

Am J Med Genet A. 2014 Aug;164A(8):2003-12. doi: 10.1002/ajmg.a.36605. Epub 2014 May 28.

PMID:
24891046
50.

P38α MAPK underlies muscular dystrophy and myofiber death through a Bax-dependent mechanism.

Wissing ER, Boyer JG, Kwong JQ, Sargent MA, Karch J, McNally EM, Otsu K, Molkentin JD.

Hum Mol Genet. 2014 Oct 15;23(20):5452-63. doi: 10.1093/hmg/ddu270. Epub 2014 May 29.

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