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Items: 25

1.

The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate.

Tortola L, Nitsch R, Bertrand MJM, Kogler M, Redouane Y, Kozieradzki I, Uribesalgo I, Fennell LM, Daugaard M, Klug H, Wirnsberger G, Wimmer R, Perlot T, Sarao R, Rao S, Hanada T, Takahashi N, Kernbauer E, Demiröz D, Lang M, Superti-Furga G, Decker T, Pichler A, Ikeda F, Kroemer G, Vandenabeele P, Sorensen PH, Penninger JM.

Cell Rep. 2016 Sep 20;16(12):3414. doi: 10.1016/j.celrep.2016.08.072. Epub 2016 Sep 20. No abstract available.

2.

RANKL/RANK control Brca1 mutation- .

Sigl V, Owusu-Boaitey K, Joshi PA, Kavirayani A, Wirnsberger G, Novatchkova M, Kozieradzki I, Schramek D, Edokobi N, Hersl J, Sampson A, Odai-Afotey A, Lazaro C, Gonzalez-Suarez E, Pujana MA, Cimba F, Heyn H, Vidal E, Cruickshank J, Berman H, Sarao R, Ticevic M, Uribesalgo I, Tortola L, Rao S, Tan Y, Pfeiler G, Lee EY, Bago-Horvath Z, Kenner L, Popper H, Singer C, Khokha R, Jones LP, Penninger JM.

Cell Res. 2016 Jul;26(7):761-74. doi: 10.1038/cr.2016.69. Epub 2016 May 31.

3.

The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate.

Tortola L, Nitsch R, Bertrand MJM, Kogler M, Redouane Y, Kozieradzki I, Uribesalgo I, Fennell LM, Daugaard M, Klug H, Wirnsberger G, Wimmer R, Perlot T, Sarao R, Rao S, Hanada T, Takahashi N, Kernbauer E, Demiröz D, Lang M, Superti-Furga G, Decker T, Pichler A, Ikeda F, Kroemer G, Vandenabeele P, Sorensen PH, Penninger JM.

Cell Rep. 2016 May 17;15(7):1481-1492. doi: 10.1016/j.celrep.2016.04.032. Epub 2016 May 5. Erratum in: Cell Rep. 2016 Sep 20;16(12 ):3414.

4.

Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense.

Wirnsberger G, Zwolanek F, Stadlmann J, Tortola L, Liu SW, Perlot T, Järvinen P, Dürnberger G, Kozieradzki I, Sarao R, De Martino A, Boztug K, Mechtler K, Kuchler K, Klein C, Elling U, Penninger JM.

Nat Genet. 2014 Sep;46(9):1028-33. doi: 10.1038/ng.3070. Epub 2014 Aug 17.

5.

Biochemical and computational analysis of LNX1 interacting proteins.

Wolting CD, Griffiths EK, Sarao R, Prevost BC, Wybenga-Groot LE, McGlade CJ.

PLoS One. 2011;6(11):e26248. doi: 10.1371/journal.pone.0026248. Epub 2011 Nov 8.

6.

Mechanical property characterization of electrospun recombinant human tropoelastin for vascular graft biomaterials.

McKenna KA, Hinds MT, Sarao RC, Wu PC, Maslen CL, Glanville RW, Babcock D, Gregory KW.

Acta Biomater. 2012 Jan;8(1):225-33. doi: 10.1016/j.actbio.2011.08.001. Epub 2011 Aug 6.

7.

Structural and cellular characterization of electrospun recombinant human tropoelastin biomaterials.

McKenna KA, Gregory KW, Sarao RC, Maslen CL, Glanville RW, Hinds MT.

J Biomater Appl. 2012 Aug;27(2):219-30. doi: 10.1177/0885328211399480. Epub 2011 May 17.

8.

Laparoscopic repair of inferior vena caval injury using a chitosan-based hemostatic dressing.

Xie H, Teach JS, Burke AP, Lucchesi LD, Wu PC, Sarao RC.

Am J Surg. 2009 Apr;197(4):510-4. doi: 10.1016/j.amjsurg.2007.12.050. Epub 2008 Jun 30.

PMID:
18585679
9.

Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes.

Pospisilik JA, Knauf C, Joza N, Benit P, Orthofer M, Cani PD, Ebersberger I, Nakashima T, Sarao R, Neely G, Esterbauer H, Kozlov A, Kahn CR, Kroemer G, Rustin P, Burcelin R, Penninger JM.

Cell. 2007 Nov 2;131(3):476-91.

10.

The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers.

Zhang L, Anglesio MS, O'Sullivan M, Zhang F, Yang G, Sarao R, Mai PN, Cronin S, Hara H, Melnyk N, Li L, Wada T, Liu PP, Farrar J, Arceci RJ, Sorensen PH, Penninger JM.

Nat Med. 2007 Sep;13(9):1060-9. Epub 2007 Aug 12.

PMID:
17694067
11.

Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload.

Kuba K, Zhang L, Imai Y, Arab S, Chen M, Maekawa Y, Leschnik M, Leibbrandt A, Markovic M, Schwaighofer J, Beetz N, Musialek R, Neely GG, Komnenovic V, Kolm U, Metzler B, Ricci R, Hara H, Meixner A, Nghiem M, Chen X, Dawood F, Wong KM, Sarao R, Cukerman E, Kimura A, Hein L, Thalhammer J, Liu PP, Penninger JM.

Circ Res. 2007 Aug 17;101(4):e32-42. Epub 2007 Aug 2. Erratum in: Circ Res. 2008 Feb 1;102(2):e36. Makovic, Mato [corrected to Markovic, Mato].

PMID:
17673668
12.

Essential role for collectrin in renal amino acid transport.

Danilczyk U, Sarao R, Remy C, Benabbas C, Stange G, Richter A, Arya S, Pospisilik JA, Singer D, Camargo SM, Makrides V, Ramadan T, Verrey F, Wagner CA, Penninger JM.

Nature. 2006 Dec 21;444(7122):1088-91. Epub 2006 Dec 13.

PMID:
17167413
13.

Regulation of cancer cell migration and bone metastasis by RANKL.

Jones DH, Nakashima T, Sanchez OH, Kozieradzki I, Komarova SV, Sarosi I, Morony S, Rubin E, Sarao R, Hojilla CV, Komnenovic V, Kong YY, Schreiber M, Dixon SJ, Sims SM, Khokha R, Wada T, Penninger JM.

Nature. 2006 Mar 30;440(7084):692-6.

PMID:
16572175
14.

Distribution of angiotensin-(1-7) and ACE2 in human placentas of normal and pathological pregnancies.

Valdés G, Neves LA, Anton L, Corthorn J, Chacón C, Germain AM, Merrill DC, Ferrario CM, Sarao R, Penninger J, Brosnihan KB.

Placenta. 2006 Feb-Mar;27(2-3):200-7. Epub 2005 Apr 25.

PMID:
16338465
15.

Angiotensin-converting enzyme 2 protects from severe acute lung failure.

Imai Y, Kuba K, Rao S, Huan Y, Guo F, Guan B, Yang P, Sarao R, Wada T, Leong-Poi H, Crackower MA, Fukamizu A, Hui CC, Hein L, Uhlig S, Slutsky AS, Jiang C, Penninger JM.

Nature. 2005 Jul 7;436(7047):112-6.

PMID:
16001071
16.

Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction.

Jeon MS, Atfield A, Venuprasad K, Krawczyk C, Sarao R, Elly C, Yang C, Arya S, Bachmaier K, Su L, Bouchard D, Jones R, Gronski M, Ohashi P, Wada T, Bloom D, Fathman CG, Liu YC, Penninger JM.

Immunity. 2004 Aug;21(2):167-77.

17.

Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure.

Oudit GY, Crackower MA, Eriksson U, Sarao R, Kozieradzki I, Sasaki T, Irie-Sasaki J, Gidrewicz D, Rybin VO, Wada T, Steinberg SF, Backx PH, Penninger JM.

Circulation. 2003 Oct 28;108(17):2147-52. Epub 2003 Sep 8.

PMID:
12963636
18.

Enhanced renal immunocytochemical expression of ANG-(1-7) and ACE2 during pregnancy.

Brosnihan KB, Neves LA, Joyner J, Averill DB, Chappell MC, Sarao R, Penninger J, Ferrario CM.

Hypertension. 2003 Oct;42(4):749-53. Epub 2003 Jul 21.

PMID:
12874086
19.

Essential role of Fkbp6 in male fertility and homologous chromosome pairing in meiosis.

Crackower MA, Kolas NK, Noguchi J, Sarao R, Kikuchi K, Kaneko H, Kobayashi E, Kawai Y, Kozieradzki I, Landers R, Mo R, Hui CC, Nieves E, Cohen PE, Osborne LR, Wada T, Kunieda T, Moens PB, Penninger JM.

Science. 2003 May 23;300(5623):1291-5.

20.

Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways.

Crackower MA, Oudit GY, Kozieradzki I, Sarao R, Sun H, Sasaki T, Hirsch E, Suzuki A, Shioi T, Irie-Sasaki J, Sah R, Cheng HY, Rybin VO, Lembo G, Fratta L, Oliveira-dos-Santos AJ, Benovic JL, Kahn CR, Izumo S, Steinberg SF, Wymann MP, Backx PH, Penninger JM.

Cell. 2002 Sep 20;110(6):737-49.

21.

Angiotensin-converting enzyme 2 is an essential regulator of heart function.

Crackower MA, Sarao R, Oudit GY, Yagil C, Kozieradzki I, Scanga SE, Oliveira-dos-Santos AJ, da Costa J, Zhang L, Pei Y, Scholey J, Ferrario CM, Manoukian AS, Chappell MC, Backx PH, Yagil Y, Penninger JM.

Nature. 2002 Jun 20;417(6891):822-8.

PMID:
12075344
22.

Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function.

Jones N, Voskas D, Master Z, Sarao R, Jones J, Dumont DJ.

EMBO Rep. 2001 May;2(5):438-45.

23.

Conditional transgene expression in endothelial cells.

Sarao R, Dumont DJ.

Transgenic Res. 1998 Nov;7(6):421-7.

PMID:
10341450
24.

The inositol polyphosphate 5-phosphatase ship is a crucial negative regulator of B cell antigen receptor signaling.

Liu Q, Oliveira-Dos-Santos AJ, Mariathasan S, Bouchard D, Jones J, Sarao R, Kozieradzki I, Ohashi PS, Penninger JM, Dumont DJ.

J Exp Med. 1998 Oct 5;188(7):1333-42.

25.

Developmentally regulated alternative RNA splicing of rat brain sodium channel mRNAs.

Sarao R, Gupta SK, Auld VJ, Dunn RJ.

Nucleic Acids Res. 1991 Oct 25;19(20):5673-9.

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