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Items: 1 to 50 of 366


Doubled-Edged Swords in the Biology of Conflict.

Sapolsky RM.

Front Psychol. 2018 Dec 20;9:2625. doi: 10.3389/fpsyg.2018.02625. eCollection 2018. Review.


The Health-Wealth Gap.

Sapolsky RM.

Sci Am. 2018 Oct 16;319(5):62-67. doi: 10.1038/scientificamerican1118-62. No abstract available.


Speculations on the Evolutionary Origins of System Justification.

Jost JT, Sapolsky RM, Nam HH.

Evol Psychol. 2018 Apr-Jun;16(2):1474704918765342. doi: 10.1177/1474704918765342. Review.


The mTOR cell signaling pathway is crucial to the long-term protective effects of ischemic postconditioning against stroke.

Wang P, Xie R, Cheng M, Sapolsky R, Ji X, Zhao H.

Neurosci Lett. 2018 May 29;676:58-65. doi: 10.1016/j.neulet.2018.03.062. Epub 2018 Mar 29.


Adult-generated neurons born during chronic social stress are uniquely adapted to respond to subsequent chronic social stress.

De Miguel Z, Haditsch U, Palmer TD, Azpiroz A, Sapolsky RM.

Mol Psychiatry. 2019 Aug;24(8):1178-1188. doi: 10.1038/s41380-017-0013-1. Epub 2018 Jan 8.


Proinflammatory primates.

Sapolsky RM.

Science. 2016 Nov 25;354(6315):967-968. No abstract available.


Psychiatric distress in animals versus animal models of psychiatric distress.

Sapolsky RM.

Nat Neurosci. 2016 Oct 26;19(11):1387-1389. doi: 10.1038/nn.4397. Review.


Fibroblast Growth Factor 2 Modulates Hypothalamic Pituitary Axis Activity and Anxiety Behavior Through Glucocorticoid Receptors.

Salmaso N, Stevens HE, McNeill J, ElSayed M, Ren Q, Maragnoli ME, Schwartz ML, Tomasi S, Sapolsky RM, Duman R, Vaccarino FM.

Biol Psychiatry. 2016 Sep 15;80(6):479-489. doi: 10.1016/j.biopsych.2016.02.026. Epub 2016 Mar 2.


Stress and the brain: individual variability and the inverted-U.

Sapolsky RM.

Nat Neurosci. 2015 Oct;18(10):1344-6. doi: 10.1038/nn.4109. Review. No abstract available.


Reducing social stress elicits emotional contagion of pain in mouse and human strangers.

Martin LJ, Hathaway G, Isbester K, Mirali S, Acland EL, Niederstrasser N, Slepian PM, Trost Z, Bartz JA, Sapolsky RM, Sternberg WF, Levitin DJ, Mogil JS.

Curr Biol. 2015 Feb 2;25(3):326-332. doi: 10.1016/j.cub.2014.11.028. Epub 2015 Jan 15.


Toxoplasma gondii is dependent on glutamine and alters migratory profile of infected host bone marrow derived immune cells through SNAT2 and CXCR4 pathways.

Lee IP, Evans AK, Yang C, Works MG, Kumar V, De Miguel Z, Manley NC, Sapolsky RM.

PLoS One. 2014 Oct 9;9(10):e109803. doi: 10.1371/journal.pone.0109803. eCollection 2014.


Glucocorticoids increase excitotoxic injury and inflammation in the hippocampus of adult male rats.

Sorrells SF, Munhoz CD, Manley NC, Yen S, Sapolsky RM.

Neuroendocrinology. 2014;100(2-3):129-40. doi: 10.1159/000367849. Epub 2014 Sep 10.


Mammalian target of rapamycin cell signaling pathway contributes to the protective effects of ischemic postconditioning against stroke.

Xie R, Wang P, Cheng M, Sapolsky R, Ji X, Zhao H.

Stroke. 2014 Sep;45(9):2769-76. doi: 10.1161/STROKEAHA.114.005406. Epub 2014 Jul 10.


Toxoplasma gondii influences aversive behaviors of female rats in an estrus cycle dependent manner.

Golcu D, Gebre RZ, Sapolsky RM.

Physiol Behav. 2014 Aug;135:98-103. doi: 10.1016/j.physbeh.2014.05.036. Epub 2014 Jun 4.


Stress and glucocorticoids promote oligodendrogenesis in the adult hippocampus.

Chetty S, Friedman AR, Taravosh-Lahn K, Kirby ED, Mirescu C, Guo F, Krupik D, Nicholas A, Geraghty A, Krishnamurthy A, Tsai MK, Covarrubias D, Wong A, Francis D, Sapolsky RM, Palmer TD, Pleasure D, Kaufer D.

Mol Psychiatry. 2014 Dec;19(12):1275-1283. doi: 10.1038/mp.2013.190. Epub 2014 Feb 11.


Patterns of Toxoplasma gondii cyst distribution in the forebrain associate with individual variation in predator odor avoidance and anxiety-related behavior in male Long-Evans rats.

Evans AK, Strassmann PS, Lee IP, Sapolsky RM.

Brain Behav Immun. 2014 Mar;37:122-33. doi: 10.1016/j.bbi.2013.11.012. Epub 2013 Nov 21.


Early postnatal handling alters glucocorticoid receptor concentrations in selected brain regions.

Meaney MJ, Aitken DH, Bodnoff SR, Iny LJ, Tatarewicz JE, Sapolsky RM.

Behav Neurosci. 2013 Oct;127(5):637-41. doi: 10.1037/a0034187.


Spatial memory and long-term object recognition are impaired by circadian arrhythmia and restored by the GABAAAntagonist pentylenetetrazole.

Ruby NF, Fernandez F, Garrett A, Klima J, Zhang P, Sapolsky R, Heller HC.

PLoS One. 2013 Aug 29;8(8):e72433. doi: 10.1371/journal.pone.0072433. eCollection 2013. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/f9111e45-33ca-47d8-b6a5-be277c292fdc.


Akt isoforms differentially protect against stroke-induced neuronal injury by regulating mTOR activities.

Xie R, Cheng M, Li M, Xiong X, Daadi M, Sapolsky RM, Zhao H.

J Cereb Blood Flow Metab. 2013 Dec;33(12):1875-85. doi: 10.1038/jcbfm.2013.132. Epub 2013 Aug 14.


Soluble TNF receptor 1-secreting ex vivo-derived dendritic cells reduce injury after stroke.

Works MG, Koenig JB, Sapolsky RM.

J Cereb Blood Flow Metab. 2013 Sep;33(9):1376-85. doi: 10.1038/jcbfm.2013.100. Epub 2013 Jun 12.


Glucocorticoid signaling in myeloid cells worsens acute CNS injury and inflammation.

Sorrells SF, Caso JR, Munhoz CD, Hu CK, Tran KV, Miguel ZD, Chien BY, Sapolsky RM.

J Neurosci. 2013 May 1;33(18):7877-89. doi: 10.1523/JNEUROSCI.4705-12.2013.


Derivation of injury-responsive dendritic cells for acute brain targeting and therapeutic protein delivery in the stroke-injured rat.

Manley NC, Caso JR, Works MG, Cutler AB, Zemlyak I, Sun G, Munhoz CD, Chang S, Sorrells SF, Ermini FV, Decker JH, Bertrand AA, Dinkel KM, Steinberg GK, Sapolsky RM.

PLoS One. 2013 Apr 16;8(4):e61789. doi: 10.1371/journal.pone.0061789. Print 2013.


Treponema pallidum infection in the wild baboons of East Africa: distribution and genetic characterization of the strains responsible.

Harper KN, Fyumagwa RD, Hoare R, Wambura PN, Coppenhaver DH, Sapolsky RM, Alberts SC, Tung J, Rogers J, Kilewo M, Batamuzi EK, Leendertz FH, Armelagos GJ, Knauf S.

PLoS One. 2012;7(12):e50882. doi: 10.1371/journal.pone.0050882. Epub 2012 Dec 20. Erratum in: PLoS One. 2014;9(3):e92489.


Toxoplasma gondii infection induces dendritic retraction in basolateral amygdala accompanied by reduced corticosterone secretion.

Mitra R, Sapolsky RM, Vyas A.

Dis Model Mech. 2013 Mar;6(2):516-20. doi: 10.1242/dmm.009928. Epub 2012 Oct 25.


Corticosterone treatment impairs auditory fear learning and the dendritic morphology of the rat inferior colliculus.

Dagnino-Subiabre A, Pérez MÁ, Terreros G, Cheng MY, House P, Sapolsky R.

Hear Res. 2012 Dec;294(1-2):104-13. doi: 10.1016/j.heares.2012.09.008. Epub 2012 Oct 23.


Importance of a sense of control and the physiological benefits of leadership.

Sapolsky RM.

Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):17730-1. doi: 10.1073/pnas.1215502109. Epub 2012 Oct 16. No abstract available.


Super Humanity.

Sapolsky RM.

Sci Am. 2012 Sep;307(3):40-3. No abstract available.


Short-term enrichment makes male rats more attractive, more defensive and alters hypothalamic neurons.

Mitra R, Sapolsky RM.

PLoS One. 2012;7(5):e36092. doi: 10.1371/journal.pone.0036092. Epub 2012 May 2.


Prokineticin 2 is an endangering mediator of cerebral ischemic injury.

Cheng MY, Lee AG, Culbertson C, Sun G, Talati RK, Manley NC, Li X, Zhao H, Lyons DM, Zhou QY, Steinberg GK, Sapolsky RM.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5475-80. doi: 10.1073/pnas.1113363109. Epub 2012 Mar 19.


Protozoan parasite Toxoplasma gondii manipulates mate choice in rats by enhancing attractiveness of males.

Dass SA, Vasudevan A, Dutta D, Soh LJ, Sapolsky RM, Vyas A.

PLoS One. 2011;6(11):e27229. doi: 10.1371/journal.pone.0027229. Epub 2011 Nov 2.


Predator cat odors activate sexual arousal pathways in brains of Toxoplasma gondii infected rats.

House PK, Vyas A, Sapolsky R.

PLoS One. 2011;6(8):e23277. doi: 10.1371/journal.pone.0023277. Epub 2011 Aug 17.


Behavior. Sympathy for the CEO.

Sapolsky RM.

Science. 2011 Jul 15;333(6040):293-4. doi: 10.1126/science.1209620. No abstract available.


Basolateral amygdala regulation of adult hippocampal neurogenesis and fear-related activation of newborn neurons.

Kirby ED, Friedman AR, Covarrubias D, Ying C, Sun WG, Goosens KA, Sapolsky RM, Kaufer D.

Mol Psychiatry. 2012 May;17(5):527-36. doi: 10.1038/mp.2011.71. Epub 2011 Jun 14.


An insult-inducible vector system activated by hypoxia and oxidative stress for neuronal gene therapy.

Cheng MY, Lee IP, Jin M, Sun G, Zhao H, Steinberg GK, Sapolsky RM.

Transl Stroke Res. 2011 Mar 1;2(1):92-100. doi: 10.1007/s12975-010-0060-2.


Transient gastric irritation in the neonatal rats leads to changes in hypothalamic CRF expression, depression- and anxiety-like behavior as adults.

Liu L, Li Q, Sapolsky R, Liao M, Mehta K, Bhargava A, Pasricha PJ.

PLoS One. 2011 May 12;6(5):e19498. doi: 10.1371/journal.pone.0019498.


Support for religio-political aggression among teenaged boys in Gaza: part II: neuroendocrinological findings.

Victoroff J, Quota S, Adelman JR, Celinska B, Stern N, Wilcox R, Sapolsky RM.

Aggress Behav. 2011 Mar-Apr;37(2):121-32. doi: 10.1002/ab.20376. Epub 2010 Nov 8.


Stress and Glucocorticoid Contributions to Normal and Pathological Aging.

Goosens KA, Sapolsky RM.

In: Riddle DR, editor. Brain Aging: Models, Methods, and Mechanisms. Boca Raton (FL): CRC Press/Taylor & Francis; 2007. Chapter 13.


Glucocorticoids exacerbate lipopolysaccharide-induced signaling in the frontal cortex and hippocampus in a dose-dependent manner.

Munhoz CD, Sorrells SF, Caso JR, Scavone C, Sapolsky RM.

J Neurosci. 2010 Oct 13;30(41):13690-8. doi: 10.1523/JNEUROSCI.0303-09.2010.


Gene therapy in rodent amygdala against fear disorders.

Mitra R, Sapolsky RM.

Expert Opin Biol Ther. 2010 Sep;10(9):1289-303. doi: 10.1517/14712598.2010.509341. Review.


Support for religio-political aggression among teenaged boys in Gaza: Part I: psychological findings.

Victoroff J, Quota S, Adelman JR, Celinska B, Stern N, Wilcox R, Sapolsky RM.

Aggress Behav. 2010 Jul-Aug;36(4):219-31. doi: 10.1002/ab.20348.


Neighbor effects of neurons bearing protective transgenes.

Lee AL, Campbell LB, Sapolsky RM.

Brain Res. 2010 Jun 21;1339:70-5. doi: 10.1016/j.brainres.2010.04.037. Epub 2010 Apr 24.


Expression of chimeric estrogen-glucocorticoid-receptor in the amygdala reduces anxiety.

Mitra R, Sapolsky RM.

Brain Res. 2010 Jun 25;1342:33-8. doi: 10.1016/j.brainres.2010.03.092. Epub 2010 Apr 8.


Anti-glucocorticoid gene therapy reverses the impairing effects of elevated corticosterone on spatial memory, hippocampal neuronal excitability, and synaptic plasticity.

Dumas TC, Gillette T, Ferguson D, Hamilton K, Sapolsky RM.

J Neurosci. 2010 Feb 3;30(5):1712-20. doi: 10.1523/JNEUROSCI.4402-09.2010.


Evidence for caspase effects on release of cytochrome c and AIF in a model of ischemia in cortical neurons.

Singh MH, Brooke SM, Zemlyak I, Sapolsky RM.

Neurosci Lett. 2010 Jan 22;469(2):179-83. doi: 10.1016/j.neulet.2009.11.067. Epub 2009 Nov 26.


Any kind of mother in a storm.

Sapolsky R.

Nat Neurosci. 2009 Nov;12(11):1355-6. doi: 10.1038/nn1109-1355. No abstract available.


The stressed CNS: when glucocorticoids aggravate inflammation.

Sorrells SF, Caso JR, Munhoz CD, Sapolsky RM.

Neuron. 2009 Oct 15;64(1):33-9. doi: 10.1016/j.neuron.2009.09.032. Review.


Glucocorticoids can arm macrophages for innate immune battle.

Sorrells SF, Sapolsky RM.

Brain Behav Immun. 2010 Jan;24(1):17-8. doi: 10.1016/j.bbi.2009.10.004. Epub 2009 Oct 12. No abstract available.


The microtubule interacting drug candidate NAP protects against kainic acid toxicity in a rat model of epilepsy.

Zemlyak I, Manley N, Vulih-Shultzman I, Cutler AB, Graber K, Sapolsky RM, Gozes I.

J Neurochem. 2009 Dec;111(5):1252-63. doi: 10.1111/j.1471-4159.2009.06415.x. Epub 2009 Oct 3.


Changes in brain MicroRNAs contribute to cholinergic stress reactions.

Meerson A, Cacheaux L, Goosens KA, Sapolsky RM, Soreq H, Kaufer D.

J Mol Neurosci. 2010 Jan;40(1-2):47-55. doi: 10.1007/s12031-009-9252-1. Epub 2009 Aug 27.

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