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Items: 1 to 50 of 56

1.

Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride.

Sap JBI, Wilson TC, Kee CW, Straathof NJW, Ende CWA, Mukherjee P, Zhang L, Genicot C, Gouverneur V.

Chem Sci. 2019 Jan 29;10(11):3237-3241. doi: 10.1039/c8sc05096a. eCollection 2019 Mar 21.

2.

Loss-of-function of PTPR γ and ζ, observed in sporadic schizophrenia, causes brain region-specific deregulation of monoamine levels and altered behavior in mice.

Cressant A, Dubreuil V, Kong J, Kranz TM, Lazarini F, Launay JM, Callebert J, Sap J, Malaspina D, Granon S, Harroch S.

Psychopharmacology (Berl). 2017 Feb;234(4):575-587. doi: 10.1007/s00213-016-4490-8. Epub 2016 Dec 26.

PMID:
28025742
3.

Receptor Protein Tyrosine Phosphatase α-Mediated Enhancement of Rheumatoid Synovial Fibroblast Signaling and Promotion of Arthritis in Mice.

Stanford SM, Svensson MN, Sacchetti C, Pilo CA, Wu DJ, Kiosses WB, Hellvard A, Bergum B, Muench GR, Elly C, Liu YC, den Hertog J, Elson A, Sap J, Mydel P, Boyle DL, Corr M, Firestein GS, Bottini N.

Arthritis Rheumatol. 2016 Feb;68(2):359-69. doi: 10.1002/art.39442.

4.

An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions.

Gomez GA, McLachlan RW, Wu SK, Caldwell BJ, Moussa E, Verma S, Bastiani M, Priya R, Parton RG, Gaus K, Sap J, Yap AS.

Mol Biol Cell. 2015 Apr 1;26(7):1249-62. doi: 10.1091/mbc.E14-07-1223. Epub 2015 Jan 28.

5.

Helicobacter pylori VacA induces apoptosis by accumulation of connexin 43 in autophagic vesicles via a Rac1/ERK-dependent pathway.

Yahiro K, Akazawa Y, Nakano M, Suzuki H, Hisatune J, Isomoto H, Sap J, Noda M, Moss J, Hirayama T.

Cell Death Discov. 2015 Sep 28;1:15035. doi: 10.1038/cddiscovery.2015.35. eCollection 2015.

6.

Protein tyrosine phosphatase regulation of stem and progenitor cell biology.

Dubreuil V, Sap J, Harroch S.

Semin Cell Dev Biol. 2015 Jan;37:82-9. doi: 10.1016/j.semcdb.2014.09.012. Epub 2014 Sep 26. Review.

PMID:
25256403
7.

RPTPα controls epithelial adherens junctions, linking E-cadherin engagement to c-Src-mediated phosphorylation of cortactin.

Truffi M, Dubreuil V, Liang X, Vacaresse N, Nigon F, Han SP, Yap AS, Gomez GA, Sap J.

J Cell Sci. 2014 Jun 1;127(Pt 11):2420-32. doi: 10.1242/jcs.134379. Epub 2014 Mar 20.

8.

Protein tyrosine phosphatase α mediates profibrotic signaling in lung fibroblasts through TGF-β responsiveness.

Aschner Y, Khalifah AP, Briones N, Yamashita C, Dolgonos L, Young SK, Campbell MN, Riches DW, Redente EF, Janssen WJ, Henson PM, Sap J, Vacaresse N, Kapus A, McCulloch CA, Zemans RL, Downey GP.

Am J Pathol. 2014 May;184(5):1489-502. doi: 10.1016/j.ajpath.2014.01.016. Epub 2014 Mar 17.

9.

A loss-of-function screen for phosphatases that regulate neurite outgrowth identifies PTPN12 as a negative regulator of TrkB tyrosine phosphorylation.

Ambjørn M, Dubreuil V, Miozzo F, Nigon F, Møller B, Issazadeh-Navikas S, Berg J, Lees M, Sap J.

PLoS One. 2013 Jun 13;8(6):e65371. doi: 10.1371/journal.pone.0065371. Print 2013.

10.

Low-density lipoprotein receptor-related protein-1 (LRP1) mediates autophagy and apoptosis caused by Helicobacter pylori VacA.

Yahiro K, Satoh M, Nakano M, Hisatsune J, Isomoto H, Sap J, Suzuki H, Nomura F, Noda M, Moss J, Hirayama T.

J Biol Chem. 2012 Sep 7;287(37):31104-15. doi: 10.1074/jbc.M112.387498. Epub 2012 Jul 22.

11.

Loss of function studies in mice and genetic association link receptor protein tyrosine phosphatase α to schizophrenia.

Takahashi N, Nielsen KS, Aleksic B, Petersen S, Ikeda M, Kushima I, Vacaresse N, Ujike H, Iwata N, Dubreuil V, Mirza N, Sakurai T, Ozaki N, Buxbaum JD, Sap J.

Biol Psychiatry. 2011 Oct 1;70(7):626-35. doi: 10.1016/j.biopsych.2011.06.016. Epub 2011 Aug 10.

12.

Regulatory effects of nitric oxide on Src kinase, FAK, p130Cas, and receptor protein tyrosine phosphatase alpha (PTP-alpha): a role for the cellular redox environment.

Curcio MF, Batista WL, Linares E, Nascimento FD, Moraes MS, Borges RE, Sap J, Stern A, Monteiro HP.

Antioxid Redox Signal. 2010 Jul 15;13(2):109-25. doi: 10.1089/ars.2009.2534.

PMID:
20055753
13.

Activation of c-Src and Fyn kinases by protein-tyrosine phosphatase RPTPalpha is substrate-specific and compatible with lipid raft localization.

Vacaresse N, Møller B, Danielsen EM, Okada M, Sap J.

J Biol Chem. 2008 Dec 19;283(51):35815-24. doi: 10.1074/jbc.M807964200. Epub 2008 Oct 23.

14.

Genes contributing to prion pathogenesis.

Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, Lisanti MP, Dwek RA, Rudd PM, Moskovitz J, Epstein CJ, Cruz TD, Kuziel WA, Maeda N, Sap J, Ashe KH, Carlson GA, Tesseur I, Wyss-Coray T, Mucke L, Weisgraber KH, Mahley RW, Cohen FE, Prusiner SB.

J Gen Virol. 2008 Jul;89(Pt 7):1777-88. doi: 10.1099/vir.0.2008/001255-0.

15.

Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent role for p38MAPK in activating transcription factor-2, cAMP response element binding protein, and NF-kappaB activation.

Hisatsune J, Nakayama M, Isomoto H, Kurazono H, Mukaida N, Mukhopadhyay AK, Azuma T, Yamaoka Y, Sap J, Yamasaki E, Yahiro K, Moss J, Hirayama T.

J Immunol. 2008 Apr 1;180(7):5017-27.

16.

RPTPalpha is required for rigidity-dependent inhibition of extension and differentiation of hippocampal neurons.

Kostic A, Sap J, Sheetz MP.

J Cell Sci. 2007 Nov 1;120(Pt 21):3895-904. Epub 2007 Oct 16.

17.

Helicobacter pylori VacA enhances prostaglandin E2 production through induction of cyclooxygenase 2 expression via a p38 mitogen-activated protein kinase/activating transcription factor 2 cascade in AZ-521 cells.

Hisatsune J, Yamasaki E, Nakayama M, Shirasaka D, Kurazono H, Katagata Y, Inoue H, Han J, Sap J, Yahiro K, Moss J, Hirayama T.

Infect Immun. 2007 Sep;75(9):4472-81. Epub 2007 Jun 25.

18.

Clustering of Helicobacter pylori VacA in lipid rafts, mediated by its receptor, receptor-like protein tyrosine phosphatase beta, is required for intoxication in AZ-521 Cells.

Nakayama M, Hisatsune J, Yamasaki E, Nishi Y, Wada A, Kurazono H, Sap J, Yahiro K, Moss J, Hirayama T.

Infect Immun. 2006 Dec;74(12):6571-80. Epub 2006 Oct 9.

19.

Tyrosine phosphatases epsilon and alpha perform specific and overlapping functions in regulation of voltage-gated potassium channels in Schwann cells.

Tiran Z, Peretz A, Sines T, Shinder V, Sap J, Attali B, Elson A.

Mol Biol Cell. 2006 Oct;17(10):4330-42. Epub 2006 Jul 26.

20.

Essential domain of receptor tyrosine phosphatase beta (RPTPbeta) for interaction with Helicobacter pylori vacuolating cytotoxin.

Yahiro K, Wada A, Yamasaki E, Nakayama M, Nishi Y, Hisatsune J, Morinaga N, Sap J, Noda M, Moss J, Hirayama T.

J Biol Chem. 2004 Dec 3;279(49):51013-21. Epub 2004 Sep 20.

21.

Receptor protein tyrosine phosphatase alpha is essential for hippocampal neuronal migration and long-term potentiation.

Petrone A, Battaglia F, Wang C, Dusa A, Su J, Zagzag D, Bianchi R, Casaccia-Bonnefil P, Arancio O, Sap J.

EMBO J. 2003 Aug 15;22(16):4121-31.

22.

RPTP-alpha acts as a transducer of mechanical force on alphav/beta3-integrin-cytoskeleton linkages.

von Wichert G, Jiang G, Kostic A, De Vos K, Sap J, Sheetz MP.

J Cell Biol. 2003 Apr 14;161(1):143-53. Epub 2003 Apr 7.

23.

The differentiation of skeletal muscle cells involves a protein-tyrosine phosphatase-alpha-mediated C-Src signaling pathway.

Lu H, Shah P, Ennis D, Shinder G, Sap J, Le-Tien H, Fantus IG.

J Biol Chem. 2002 Nov 29;277(48):46687-95. Epub 2002 Sep 25.

24.
25.

Expression of protein tyrosine phosphatase alpha (RPTPalpha) in human breast cancer correlates with low tumor grade, and inhibits tumor cell growth in vitro and in vivo.

Ardini E, Agresti R, Tagliabue E, Greco M, Aiello P, Yang LT, Ménard S, Sap J.

Oncogene. 2000 Oct 12;19(43):4979-87.

26.
27.

Dimerization inhibits the activity of receptor-like protein-tyrosine phosphatase-alpha.

Jiang G, den Hertog J, Su J, Noel J, Sap J, Hunter T.

Nature. 1999 Oct 7;401(6753):606-10.

PMID:
10524630
29.

Expression of a truncated receptor protein tyrosine phosphatase kappa in the brain of an adult transgenic mouse.

Shen P, Canoll PD, Sap J, Musacchio JM.

Brain Res. 1999 May 1;826(2):157-71.

PMID:
10224293
30.

Overexpression of protein tyrosine phosphatase-alpha (PTP-alpha) but not PTP-kappa inhibits translocation of GLUT4 in rat adipose cells.

Cong LN, Chen H, Li Y, Lin CH, Sap J, Quon MJ.

Biochem Biophys Res Commun. 1999 Feb 16;255(2):200-7.

PMID:
10049686
31.
33.

Homophilic interactions mediated by receptor tyrosine phosphatases mu and kappa. A critical role for the novel extracellular MAM domain.

Zondag GC, Koningstein GM, Jiang YP, Sap J, Moolenaar WH, Gebbink MF.

J Biol Chem. 1995 Jun 16;270(24):14247-50. Erratum in: J Biol Chem 1995 Oct 13;270(41):24621.

34.

Stimulation of receptor protein-tyrosine phosphatase alpha activity and phosphorylation by phorbol ester.

den Hertog J, Sap J, Pals CE, Schlessinger J, Kruijer W.

Cell Growth Differ. 1995 Mar;6(3):303-7.

35.

The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulation.

Desai DM, Sap J, Silvennoinen O, Schlessinger J, Weiss A.

EMBO J. 1994 Sep 1;13(17):4002-10.

36.
37.

Receptor tyrosine phosphatase beta is expressed in the form of proteoglycan and binds to the extracellular matrix protein tenascin.

Barnea G, Grumet M, Milev P, Silvennoinen O, Levy JB, Sap J, Schlessinger J.

J Biol Chem. 1994 May 20;269(20):14349-52.

38.

Multiple forms of the human tyrosine phosphatase RPTP alpha. Isozymes and differences in glycosylation.

Daum G, Regenass S, Sap J, Schlessinger J, Fischer EH.

J Biol Chem. 1994 Apr 8;269(14):10524-8.

39.

Close similarity between receptor-linked tyrosine phosphatase and rat brain proteoglycan.

Barnea G, Grumet M, Sap J, Margolis RU, Schlessinger J.

Cell. 1994 Jan 28;76(2):205. No abstract available.

PMID:
8293458
40.

Receptor tyrosine phosphatase R-PTP-kappa mediates homophilic binding.

Sap J, Jiang YP, Friedlander D, Grumet M, Schlessinger J.

Mol Cell Biol. 1994 Jan;14(1):1-9.

41.

The expression of a novel receptor-type tyrosine phosphatase suggests a role in morphogenesis and plasticity of the nervous system.

Canoll PD, Barnea G, Levy JB, Sap J, Ehrlich M, Silvennoinen O, Schlessinger J, Musacchio JM.

Brain Res Dev Brain Res. 1993 Oct 15;75(2):293-8.

PMID:
8261619
42.

Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase.

Desai DM, Sap J, Schlessinger J, Weiss A.

Cell. 1993 May 7;73(3):541-54.

PMID:
8490965
44.

The gene for receptor-linked protein-tyrosine-phosphatase (PTPA) is assigned to human chromosome 20p12-pter by in situ hybridization (ISH and FISH).

Rao VV, Löffler C, Sap J, Schlessinger J, Hansmann I.

Genomics. 1992 Jul;13(3):906-7. No abstract available.

PMID:
1639427
45.

v-erbA overexpression is required to extinguish c-erbA function in erythroid cell differentiation and regulation of the erbA target gene CAII.

Disela C, Glineur C, Bugge T, Sap J, Stengl G, Dodgson J, Stunnenberg H, Beug H, Zenke M.

Genes Dev. 1991 Nov;5(11):2033-47.

46.

Ectopic expression of the erythrocyte band 3 anion exchange protein, using a new avian retrovirus vector.

Fuerstenberg S, Beug H, Introna M, Khazaie K, Muñoz A, Ness S, Nordström K, Sap J, Stanley I, Zenke M, et al.

J Virol. 1990 Dec;64(12):5891-902.

47.

Cloning and expression of a widely expressed receptor tyrosine phosphatase.

Sap J, D'Eustachio P, Givol D, Schlessinger J.

Proc Natl Acad Sci U S A. 1990 Aug;87(16):6112-6.

48.

v-erbA oncogene activation entails the loss of hormone-dependent regulator activity of c-erbA.

Zenke M, Muñoz A, Sap J, Vennström B, Beug H.

Cell. 1990 Jun 15;61(6):1035-49.

PMID:
1972036
49.

A major thyroid hormone response element in the third intron of the rat growth hormone gene.

Sap J, de Magistris L, Stunnenberg H, Vennström B.

EMBO J. 1990 Mar;9(3):887-96.

50.

The chicken c-erbA alpha-product induces expression of thyroid hormone-responsive genes in 3,5,3'-triiodothyronine receptor-deficient rat hepatoma cells.

Muñoz A, Höppner W, Sap J, Brady G, Nordström K, Seitz HJ, Vennström B.

Mol Endocrinol. 1990 Feb;4(2):312-20.

PMID:
2158623

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