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Items: 9


Allele-specific Alterations in the Peptidome Underlie the Joint Association of HLA-A*29:02 and Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) with Birdshot Chorioretinopathy.

Sanz-Bravo A, Martín-Esteban A, Kuiper JJW, García-Peydró M, Barnea E, Admon A, López de Castro JA.

Mol Cell Proteomics. 2018 Aug;17(8):1564-1577. doi: 10.1074/mcp.RA118.000778. Epub 2018 May 16.


Ranking the Contribution of Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) Polymorphisms to Shaping the HLA-B*27 Peptidome.

Sanz-Bravo A, Alvarez-Navarro C, Martín-Esteban A, Barnea E, Admon A, López de Castro JA.

Mol Cell Proteomics. 2018 Jul;17(7):1308-1323. doi: 10.1074/mcp.RA117.000565. Epub 2018 Apr 9.


Separate effects of the ankylosing spondylitis associated ERAP1 and ERAP2 aminopeptidases determine the influence of their combined phenotype on the HLA-B*27 peptidome.

Martín-Esteban A, Sanz-Bravo A, Guasp P, Barnea E, Admon A, López de Castro JA.

J Autoimmun. 2017 May;79:28-38. doi: 10.1016/j.jaut.2016.12.008. Epub 2017 Jan 4.


Molecular and pathogenic effects of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in MHC-I-associated inflammatory disorders: Towards a unifying view.

López de Castro JA, Alvarez-Navarro C, Brito A, Guasp P, Martín-Esteban A, Sanz-Bravo A.

Mol Immunol. 2016 Sep;77:193-204. doi: 10.1016/j.molimm.2016.08.005. Epub 2016 Aug 11. Review.


Dominant role of the ERAP1 polymorphism R528K in shaping the HLA-B27 Peptidome through differential processing determined by multiple peptide residues.

Sanz-Bravo A, Campos J, Mazariegos MS, López de Castro JA.

Arthritis Rheumatol. 2015 Mar;67(3):692-701. doi: 10.1002/art.38980.


Peptide handling by HLA-B27 subtypes influences their biological behavior, association with ankylosing spondylitis and susceptibility to endoplasmic reticulum aminopeptidase 1 (ERAP1).

García-Medel N, Sanz-Bravo A, Alvarez-Navarro C, Gómez-Molina P, Barnea E, Marcilla M, Admon A, de Castro JA.

Mol Cell Proteomics. 2014 Dec;13(12):3367-80. doi: 10.1074/mcp.M114.039214. Epub 2014 Sep 3.


Combined effects of ankylosing spondylitis-associated ERAP1 polymorphisms outside the catalytic and peptide-binding sites on the processing of natural HLA-B27 ligands.

Martín-Esteban A, Gómez-Molina P, Sanz-Bravo A, López de Castro JA.

J Biol Chem. 2014 Feb 14;289(7):3978-90. doi: 10.1074/jbc.M113.529610. Epub 2013 Dec 18.


Functional interaction of the ankylosing spondylitis-associated endoplasmic reticulum aminopeptidase 1 polymorphism and HLA-B27 in vivo.

García-Medel N, Sanz-Bravo A, Van Nguyen D, Galocha B, Gómez-Molina P, Martín-Esteban A, Alvarez-Navarro C, de Castro JA.

Mol Cell Proteomics. 2012 Nov;11(11):1416-29. doi: 10.1074/mcp.M112.019588. Epub 2012 Aug 23.


The origin of proteasome-inhibitor resistant HLA class I peptidomes: a study with HLA-A*68:01.

García-Medel N, Sanz-Bravo A, Barnea E, Admon A, López de Castro JA.

Mol Cell Proteomics. 2012 Jan;11(1):M111.011486. doi: 10.1074/mcp.M111.011486. Epub 2011 Oct 3.

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