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Items: 1 to 50 of 214

1.

The Abnormal CD4+T Lymphocyte Subset Distribution and Vbeta Repertoire in New-onset Rheumatoid Arthritis Can Be Modulated by Methotrexate Treament.

Monserrat J, Bohórquez C, Gómez Lahoz AM, Movasat A, Pérez A, Ruíz L, Díaz D, Chara L, Sánchez AI, Albarrán F, Sanz I, Álvarez-Mon M.

Cells. 2019 Aug 10;8(8). pii: E871. doi: 10.3390/cells8080871.

2.

Clustered Mutations at the Murine and Human IgH Locus Exhibit Significant Linkage Consistent with Templated Mutagenesis.

Dale GA, Wilkins DJ, Bohannon CD, Dilernia D, Hunter E, Bedford T, Antia R, Sanz I, Jacob J.

J Immunol. 2019 Sep 1;203(5):1252-1264. doi: 10.4049/jimmunol.1801615. Epub 2019 Aug 2.

PMID:
31375545
3.

Epigenetic programming underpins B cell dysfunction in human SLE.

Scharer CD, Blalock EL, Mi T, Barwick BG, Jenks SA, Deguchi T, Cashman KS, Neary BE, Patterson DG, Hicks SL, Khosroshahi A, Eun-Hyung Lee F, Wei C, Sanz I, Boss JM.

Nat Immunol. 2019 Aug;20(8):1071-1082. doi: 10.1038/s41590-019-0419-9. Epub 2019 Jul 1.

PMID:
31263277
4.

IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation.

Zumaquero E, Stone SL, Scharer CD, Jenks SA, Nellore A, Mousseau B, Rosal-Vela A, Botta D, Bradley JE, Wojciechowski W, Ptacek T, Danila MI, Edberg JC, Bridges SL Jr, Kimberly RP, Chatham WW, Schoeb TR, Rosenberg AF, Boss JM, Sanz I, Lund FE.

Elife. 2019 May 15;8. pii: e41641. doi: 10.7554/eLife.41641.

5.

Differential transcriptome and development of human peripheral plasma cell subsets.

Garimalla S, Nguyen DC, Halliley JL, Tipton C, Rosenberg AF, Fucile CF, Saney CL, Kyu S, Kaminski D, Qian Y, Scheuermann RH, Gibson G, Sanz I, Lee FE.

JCI Insight. 2019 May 2;4(9). pii: 126732. doi: 10.1172/jci.insight.126732. eCollection 2019 May 2.

6.

Extrafollicular responses in humans and SLE.

Jenks SA, Cashman KS, Woodruff MC, Lee FE, Sanz I.

Immunol Rev. 2019 Mar;288(1):136-148. doi: 10.1111/imr.12741. Review.

PMID:
30874345
7.

Heterotypic Neuraminidase Antibodies Against Different A(H1N1) Strains are Elicited after Seasonal Influenza Vaccination.

Mendez-Legaza JM, Ortiz de Lejarazu R, Sanz I.

Vaccines (Basel). 2019 Mar 13;7(1). pii: E30. doi: 10.3390/vaccines7010030.

8.

Which partial pressure of carbon dioxide during extracorporeal cardiopulmonary resuscitation (ECPR)?

Morris KP, Brincat E, Sanz I, Scholefield BR.

Resuscitation. 2019 May;138:42-43. doi: 10.1016/j.resuscitation.2019.02.037. Epub 2019 Mar 8. No abstract available.

PMID:
30853624
9.

T-bet+ B cells: A common denominator in protective and autoreactive antibody responses?

Myles A, Sanz I, Cancro MP.

Curr Opin Immunol. 2019 Apr;57:40-45. doi: 10.1016/j.coi.2019.01.002. Epub 2019 Feb 19. Review.

PMID:
30784957
10.

Author Correction: Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion.

Nguyen DC, Garimalla S, Xiao H, Kyu S, Albizua I, Galipeau J, Chiang KY, Waller EK, Wu R, Gibson G, Roberson J, Lund FE, Randall TD, Sanz I, Lee FE.

Nat Commun. 2019 Jan 17;10(1):372. doi: 10.1038/s41467-019-08400-0.

11.

PD-1 immunobiology in systemic lupus erythematosus.

Curran CS, Gupta S, Sanz I, Sharon E.

J Autoimmun. 2019 Feb;97:1-9. doi: 10.1016/j.jaut.2018.10.025. Epub 2018 Nov 3. Review.

PMID:
30396745
12.

Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus.

Jenks SA, Cashman KS, Zumaquero E, Marigorta UM, Patel AV, Wang X, Tomar D, Woodruff MC, Simon Z, Bugrovsky R, Blalock EL, Scharer CD, Tipton CM, Wei C, Lim SS, Petri M, Niewold TB, Anolik JH, Gibson G, Lee FE, Boss JM, Lund FE, Sanz I.

Immunity. 2018 Oct 16;49(4):725-739.e6. doi: 10.1016/j.immuni.2018.08.015. Epub 2018 Oct 9.

PMID:
30314758
13.

Incidence of Hypersensitivity Reactions During Hemodialysis.

Esteras R, Martín-Navarro J, Ledesma G, Fernández-Prado R, Carreño G, Cintra M, Cidraque I, Sanz I, Tarragón B, Alexandru S, Milla M, Astudillo E, Sánchez E, Mas S, Tejeiro RD, Ortiz A, Sánchez R, González-Parra E.

Kidney Blood Press Res. 2018;43(5):1472-1478. doi: 10.1159/000493662. Epub 2018 Sep 20.

14.

Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion.

Nguyen DC, Garimalla S, Xiao H, Kyu S, Albizua I, Galipeau J, Chiang KY, Waller EK, Wu R, Gibson G, Roberson J, Lund FE, Randall TD, Sanz I, Lee FE.

Nat Commun. 2018 Sep 12;9(1):3698. doi: 10.1038/s41467-018-05853-7. Erratum in: Nat Commun. 2019 Jan 17;10(1):372.

15.

Cutting Edge: Intracellular IFN-β and Distinct Type I IFN Expression Patterns in Circulating Systemic Lupus Erythematosus B Cells.

Hamilton JA, Wu Q, Yang P, Luo B, Liu S, Li J, L Mattheyses A, Sanz I, Chatham WW, Hsu HC, Mountz JD.

J Immunol. 2018 Oct 15;201(8):2203-2208. doi: 10.4049/jimmunol.1800791. Epub 2018 Sep 10.

PMID:
30201809
16.

Understanding B-cell activation and autoantibody repertoire selection in systemic lupus erythematosus: A B-cell immunomics approach.

Tipton CM, Hom JR, Fucile CF, Rosenberg AF, Sanz I.

Immunol Rev. 2018 Jul;284(1):120-131. doi: 10.1111/imr.12660. Review.

17.

The SLE-key test serological signature: new insights into the course of lupus.

Putterman C, Pisetsky DS, Petri M, Caricchio R, Wu AHB, Sanz I, Oates JC, Wallace S, Sorek R, Gerwien R, Safer P, Jakobi-Brook K, Cohen IR.

Rheumatology (Oxford). 2018 Sep 1;57(9):1632-1640. doi: 10.1093/rheumatology/key149.

18.

Clinical Efficacy and Safety of Baminercept, a Lymphotoxin β Receptor Fusion Protein, in Primary Sjögren's Syndrome: Results From a Phase II Randomized, Double-Blind, Placebo-Controlled Trial.

St Clair EW, Baer AN, Wei C, Noaiseh G, Parke A, Coca A, Utset TO, Genovese MC, Wallace DJ, McNamara J, Boyle K, Keyes-Elstein L, Browning JL, Franchimont N, Smith K, Guthridge JM, Sanz I, James JA; Autoimmunity Centers of Excellence.

Arthritis Rheumatol. 2018 Sep;70(9):1470-1480. doi: 10.1002/art.40513. Epub 2018 Jul 18.

19.

BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data.

Upadhyay AA, Kauffman RC, Wolabaugh AN, Cho A, Patel NB, Reiss SM, Havenar-Daughton C, Dawoud RA, Tharp GK, Sanz I, Pulendran B, Crotty S, Lee FE, Wrammert J, Bosinger SE.

Genome Med. 2018 Mar 20;10(1):20. doi: 10.1186/s13073-018-0528-3.

20.

Randomized trial of omega-3 for autism spectrum disorders: Effect on cell membrane composition and behavior.

Parellada M, Llorente C, Calvo R, Gutierrez S, Lázaro L, Graell M, Guisasola M, Dorado ML, Boada L, Romo J, Dulin E, Sanz I, Arango C, Moreno C.

Eur Neuropsychopharmacol. 2017 Dec;27(12):1319-1330. doi: 10.1016/j.euroneuro.2017.08.426. Epub 2017 Sep 19.

PMID:
28935269
21.

Heterologous Humoral Response against H5N1, H7N3, and H9N2 Avian Influenza Viruses after Seasonal Vaccination in a European Elderly Population.

Sanz I, Rojo S, Tamames S, Eiros JM, Ortiz de Lejarazu R.

Vaccines (Basel). 2017 Jul 17;5(3). pii: E17. doi: 10.3390/vaccines5030017.

22.

Autoreactive monoclonal antibodies from patients with primary biliary cholangitis recognize environmental xenobiotics.

Tanaka T, Zhang W, Sun Y, Shuai Z, Chida AS, Kenny TP, Yang GX, Sanz I, Ansari A, Bowlus CL, Ippolito GC, Coppel RL, Okazaki K, He XS, Leung PSC, Gershwin ME.

Hepatology. 2017 Sep;66(3):885-895. doi: 10.1002/hep.29245. Epub 2017 Jul 20.

23.

B Cell Receptor Genes Associated With Tolerance Identify a Cohort of Immunosuppressed Patients With Improved Renal Allograft Graft Function.

Asare A, Kanaparthi S, Lim N, Phippard D, Vincenti F, Friedewald J, Pavlakis M, Poggio E, Heeger P, Mannon R, Burrell BE, Morrison Y, Bridges N, Sanz I, Chandraker A, Newell KA, Turka LA.

Am J Transplant. 2017 Oct;17(10):2627-2639. doi: 10.1111/ajt.14283. Epub 2017 May 2.

24.

New Perspectives in Rheumatology: May You Live in Interesting Times: Challenges and Opportunities in Lupus Research.

Sanz I.

Arthritis Rheumatol. 2017 Aug;69(8):1552-1559. doi: 10.1002/art.40109. Epub 2017 Jun 16. No abstract available.

25.

Notes from the Field: An Outbreak of Salmonella Typhimurium Associated with Playground Sand in a Preschool Setting - Madrid, Spain, September-October 2016.

Lucerón CO, Meixeira AP, Sanz IA, Deleyto VC, León SH, Ruiz LG.

MMWR Morb Mortal Wkly Rep. 2017 Mar 10;66(9):256-257. doi: 10.15585/mmwr.mm6609a3. No abstract available.

26.

PKK deficiency in B cells prevents lupus development in Sle lupus mice.

Oleksyn D, Zhao J, Vosoughi A, Zhao JC, Misra R, Pentland AP, Ryan D, Anolik J, Ritchlin C, Looney J, Anandarajah AP, Schwartz G, Calvi LM, Georger M, Mohan C, Sanz I, Chen L.

Immunol Lett. 2017 May;185:1-11. doi: 10.1016/j.imlet.2017.03.002. Epub 2017 Mar 6.

27.

Pre-existing neutralizing antibody mitigates B cell dysregulation and enhances the Env-specific antibody response in SHIV-infected rhesus macaques.

Jaworski JP, Bryk P, Brower Z, Zheng B, Hessell AJ, Rosenberg AF, Wu TT, Sanz I, Keefer MC, Haigwood NL, Kobie JJ.

PLoS One. 2017 Feb 21;12(2):e0172524. doi: 10.1371/journal.pone.0172524. eCollection 2017.

28.

Role of Myocardial Collagen in Severe Aortic Stenosis With Preserved Ejection Fraction and Symptoms of Heart Failure.

Echegaray K, Andreu I, Lazkano A, Villanueva I, Sáenz A, Elizalde MR, Echeverría T, López B, Garro A, González A, Zubillaga E, Solla I, Sanz I, González J, Elósegui-Artola A, Roca-Cusachs P, Díez J, Ravassa S, Querejeta R.

Rev Esp Cardiol (Engl Ed). 2017 Oct;70(10):832-840. doi: 10.1016/j.rec.2016.12.038. Epub 2017 Feb 16. English, Spanish.

PMID:
28215921
29.

Infectious encephalitis: utility of a rational approach to aetiological diagnosis in daily clinical practice.

López-Sánchez C, Sulleiro E, Bocanegra C, Romero S, Codina G, Sanz I, Esperalba J, Serra J, Pigrau C, Burgos J, Almirante B, Falcó V.

Eur J Clin Microbiol Infect Dis. 2017 Apr;36(4):641-648. doi: 10.1007/s10096-016-2840-4. Epub 2016 Nov 25.

PMID:
27888402
30.

Systemic lupus erythematosus: Extent and patterns of off-label use of rituximab for SLE.

Sanz I.

Nat Rev Rheumatol. 2016 Nov 22;12(12):700-702. doi: 10.1038/nrrheum.2016.191. No abstract available.

31.

The Regulation of Inherently Autoreactive VH4-34-Expressing B Cells in Individuals Living in a Malaria-Endemic Area of West Africa.

Hart GT, Akkaya M, Chida AS, Wei C, Jenks SA, Tipton C, He C, Wendel BS, Skinner J, Arora G, Kayentao K, Ongoiba A, Doumbo O, Traore B, Narum DL, Jiang N, Crompton PD, Sanz I, Pierce SK.

J Immunol. 2016 Nov 15;197(10):3841-3849. Epub 2016 Oct 19.

32.

Corrigendum: Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection.

Bohannon C, Powers R, Satyabhama L, Cui A, Tipton C, Michaeli M, Skountzou I, Mittler RS, Kleinstein SH, Mehr R, Lee FE, Sanz I, Jacob J.

Nat Commun. 2016 Aug 16;7:12687. doi: 10.1038/ncomms12687. No abstract available.

33.

Recommendations of the Spanish Society of Pneumology and Thoracic Surgery on the diagnosis and treatment of non-small-cell lung cancer.

Álvarez FV, Trueba IM, Sanchis JB, López-Rodó LM, Rodríguez Suárez PM, de Cos Escuín JS, Barreiro E, Henar Borrego Pintado M, Vicente CD, Aldeyturriaga JF, Gámez García P, Garrido López P, León Atance P, Izquierdo Elena JM, Novoa Valentín NM, Rivas de Andrés JJ, Crespo ÍR, Velázquez ÁS, Seijo Maceiras LM, Reina SS, Bujanda DA, Ávila Martínez RJ, de Granda Orive JI, Martínez Ede H, Gude VD, Flor RE, Freixinet Gilart JL, García Jiménez MD, Alarza FH, Sarmiento SH, Honguero Martínez AF, Jiménez Ruiz CA, Sanz IL, Mariscal de Alba A, Martínez Vallina P, Menal Muñoz P, Pérez LM, Olmedo García ME, Rombolá CA, Arregui ÍS, Somiedo Gutiérrez Mdel V, Triviño Ramírez AI, Trujillo Reyes JC, Vallejo C, Lozano PV, Simó GV, Zulueta JJ.

Arch Bronconeumol. 2016 May;52 Suppl 1:2-62. doi: 10.1016/S0300-2896(16)30198-3. English, Spanish. No abstract available.

34.

Supported bifunctional thioureas as recoverable and reusable catalysts for enantioselective nitro-Michael reactions.

Andrés JM, Ceballos M, Maestro A, Sanz I, Pedrosa R.

Beilstein J Org Chem. 2016 Apr 1;12:628-35. doi: 10.3762/bjoc.12.61. eCollection 2016.

35.

Editorial: IgA Responses and Future Development of Rheumatoid Arthritis.

Sanz I.

Arthritis Rheumatol. 2016 Oct;68(10):2351-3. doi: 10.1002/art.39789. No abstract available.

36.

Digestion of Chromatin in Apoptotic Cell Microparticles Prevents Autoimmunity.

Sisirak V, Sally B, D'Agati V, Martinez-Ortiz W, Özçakar ZB, David J, Rashidfarrokhi A, Yeste A, Panea C, Chida AS, Bogunovic M, Ivanov II, Quintana FJ, Sanz I, Elkon KB, Tekin M, Yalçınkaya F, Cardozo TJ, Clancy RM, Buyon JP, Reizis B.

Cell. 2016 Jun 30;166(1):88-101. doi: 10.1016/j.cell.2016.05.034. Epub 2016 Jun 9.

37.

Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection.

Bohannon C, Powers R, Satyabhama L, Cui A, Tipton C, Michaeli M, Skountzou I, Mittler RS, Kleinstein SH, Mehr R, Lee FE, Sanz I, Jacob J.

Nat Commun. 2016 Jun 7;7:11826. doi: 10.1038/ncomms11826. Erratum in: Nat Commun. 2016 Aug 16;7:12687. Lee, Francis Eun-Hyung [Lee, Frances Eun-Hyung].

38.

ATAC-seq on biobanked specimens defines a unique chromatin accessibility structure in naïve SLE B cells.

Scharer CD, Blalock EL, Barwick BG, Haines RR, Wei C, Sanz I, Boss JM.

Sci Rep. 2016 Jun 1;6:27030. doi: 10.1038/srep27030.

39.

Antibody-Array-Based Proteomic Screening of Serum Markers in Systemic Lupus Erythematosus: A Discovery Study.

Wu T, Ding H, Han J, Arriens C, Wei C, Han W, Pedroza C, Jiang S, Anolik J, Petri M, Sanz I, Saxena R, Mohan C.

J Proteome Res. 2016 Jul 1;15(7):2102-14. doi: 10.1021/acs.jproteome.5b00905. Epub 2016 Jun 7.

40.

Identification of human plasma cells with a lamprey monoclonal antibody.

Yu C, Liu Y, Chan JTH, Tong J, Li Z, Shi M, Davani D, Parsons M, Khan S, Zhan W, Kyu S, Grunebaum E, Campisi P, Propst EJ, Jaye DL, Trudel S, Moran MF, Ostrowski M, Herrin BR, Lee FE, Sanz I, Cooper MD, Ehrhardt GR.

JCI Insight. 2016;1(3). pii: 84738. doi: 10.1172/jci.insight.84738. Epub 2016 Mar 17.

41.

A critical role for the protein kinase PKK in the maintenance of recirculating mature B cells and the development of B1 cells.

Chen L, Oleksyn D, Pulvino M, Sanz I, Ryan D, Ryan C, Lin CS, Poligone B, Pentland AP, Ritchlin C, Zhao J.

Immunol Lett. 2016 Apr;172:67-78. doi: 10.1016/j.imlet.2016.02.015. Epub 2016 Feb 26.

PMID:
26921474
42.

SLE-key(®) rule-out serologic test for excluding the diagnosis of systemic lupus erythematosus: Developing the ImmunArray iCHIP(®).

Putterman C, Wu A, Reiner-Benaim A, Batty DS Jr, Sanz I, Oates J, Jakobi K, Petri M, Safer P, Gerwien R, Sorek R, Blumenstein Y, Cohen IR.

J Immunol Methods. 2016 Feb;429:1-6. doi: 10.1016/j.jim.2015.12.003. Epub 2015 Dec 8.

43.

Simultaneous influenza A and B infection in a pregnant woman in the context of influenza A family cluster.

Sanz I, Rojo S, Eiros JM, Tamames S, Vega T, Ortiz de Lejarazu R.

J Clin Virol. 2015 Dec;73:52-54. doi: 10.1016/j.jcv.2015.10.017. Epub 2015 Oct 28. No abstract available.

PMID:
26546876
44.

Longitudinal studies of a B cell-derived signature of tolerance in renal transplant recipients.

Newell KA, Asare A, Sanz I, Wei C, Rosenberg A, Gao Z, Kanaparthi S, Asare S, Lim N, Stahly M, Howell M, Knechtle S, Kirk A, Marks WH, Kawai T, Spitzer T, Tolkoff-Rubin N, Sykes M, Sachs DH, Cosimi AB, Burlingham WJ, Phippard D, Turka LA.

Am J Transplant. 2015 Nov;15(11):2908-20. doi: 10.1111/ajt.13480. Epub 2015 Oct 13.

45.

Altered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich syndrome.

Kolhatkar NS, Brahmandam A, Thouvenel CD, Becker-Herman S, Jacobs HM, Schwartz MA, Allenspach EJ, Khim S, Panigrahi AK, Luning Prak ET, Thrasher AJ, Notarangelo LD, Candotti F, Torgerson TR, Sanz I, Rawlings DJ.

J Exp Med. 2015 Sep 21;212(10):1663-77. doi: 10.1084/jem.20150585. Epub 2015 Sep 14.

46.

Long-Lived Plasma Cells Are Contained within the CD19(-)CD38(hi)CD138(+) Subset in Human Bone Marrow.

Halliley JL, Tipton CM, Liesveld J, Rosenberg AF, Darce J, Gregoretti IV, Popova L, Kaminiski D, Fucile CF, Albizua I, Kyu S, Chiang KY, Bradley KT, Burack R, Slifka M, Hammarlund E, Wu H, Zhao L, Walsh EE, Falsey AR, Randall TD, Cheung WC, Sanz I, Lee FE.

Immunity. 2015 Jul 21;43(1):132-45. doi: 10.1016/j.immuni.2015.06.016. Epub 2015 Jul 14.

47.

Viral Etiology of Chronic Obstructive Pulmonary Disease Exacerbations during the A/H1N1pdm09 Pandemic and Postpandemic Period.

Sanz I, Tamames S, Rojo S, Justel M, Lozano JE, Disdier C, Vega T, Ortiz de Lejarazu R.

Adv Virol. 2015;2015:560679. doi: 10.1155/2015/560679. Epub 2015 May 7.

48.

Expansion of Activated Peripheral Blood Memory B Cells in Rheumatoid Arthritis, Impact of B Cell Depletion Therapy, and Biomarkers of Response.

Adlowitz DG, Barnard J, Biear JN, Cistrone C, Owen T, Wang W, Palanichamy A, Ezealah E, Campbell D, Wei C, Looney RJ, Sanz I, Anolik JH.

PLoS One. 2015 Jun 5;10(6):e0128269. doi: 10.1371/journal.pone.0128269. eCollection 2015.

49.

Evaluation of two commercially available chromogenic media for confirmation of methicillin-resistant Staphylococcus aureus from human, animal, and food samples.

Ariza-Miguel J, Oniciuc EA, Sanz I, Fernández-Natal I, Hernández M, Rodríguez-Lázaro D.

Int J Food Microbiol. 2015 Sep 16;209:26-8. doi: 10.1016/j.ijfoodmicro.2015.05.004. Epub 2015 May 12.

PMID:
26026664
50.

Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus.

Tipton CM, Fucile CF, Darce J, Chida A, Ichikawa T, Gregoretti I, Schieferl S, Hom J, Jenks S, Feldman RJ, Mehr R, Wei C, Lee FE, Cheung WC, Rosenberg AF, Sanz I.

Nat Immunol. 2015 Jul;16(7):755-65. doi: 10.1038/ni.3175. Epub 2015 May 25.

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