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Items: 1 to 50 of 404

1.

The DisGeNET knowledge platform for disease genomics: 2019 update.

Piñero J, Ramírez-Anguita JM, Saüch-Pitarch J, Ronzano F, Centeno E, Sanz F, Furlong LI.

Nucleic Acids Res. 2019 Nov 4. pii: gkz1021. doi: 10.1093/nar/gkz1021. [Epub ahead of print]

PMID:
31680165
2.

Prevalence and risk factors for Enterobacteriaceae in patients hospitalized with community-acquired pneumonia.

Villafuerte D, Aliberti S, Soni NJ, Faverio P, Marcos PJ, Wunderink RG, Rodriguez A, Sibila O, Sanz F, Martin-Loeches I, Menzella F, Reyes LF, Jankovic M, Spielmanns M, Restrepo MI; GLIMP Investigators.

Respirology. 2019 Aug 5. doi: 10.1111/resp.13663. [Epub ahead of print]

PMID:
31385399
3.

International prevalence and risk factors evaluation for drug-resistant Streptococcus pneumoniae pneumonia.

Aliberti S, Cook GS, Babu BL, Reyes LF, H Rodriguez A, Sanz F, Soni NJ, Anzueto A, Faverio P, Sadud RF, Muhammad I, Prat C, Vendrell E, Neves J, Kaimakamis E, Feneley A, Swarnakar R, Franzetti F, Carugati M, Morosi M, Monge E, Restrepo MI; GLIMP investigators.

J Infect. 2019 Oct;79(4):300-311. doi: 10.1016/j.jinf.2019.07.004. Epub 2019 Jul 9.

PMID:
31299410
4.

Detecting Signs of Depression in Tweets in Spanish: Behavioral and Linguistic Analysis.

Leis A, Ronzano F, Mayer MA, Furlong LI, Sanz F.

J Med Internet Res. 2019 Jun 27;21(6):e14199. doi: 10.2196/14199.

5.

High-Density Autologous Chondrocyte Implantation as Treatment for Ankle Osteochondral Defects.

López-Alcorocho JM, Guillén-Vicente I, Rodríguez-Iñigo E, Navarro R, Caballero-Santos R, Guillén-Vicente M, Casqueiro M, Fernández-Jaén TF, Sanz F, Arauz S, Abelow S, Guillén-García P.

Cartilage. 2019 Mar 17:1947603519835898. doi: 10.1177/1947603519835898. [Epub ahead of print]

PMID:
30880428
6.

Cryptic Resistance Mutations Associated With Misdiagnoses of Multidrug-Resistant Tuberculosis.

Cancino-Muñoz I, Moreno-Molina M, Furió V, Goig GA, Torres-Puente M, Chiner-Oms Á, Villamayor LM, Sanz F, Guna-Serrano MR, Comas I.

J Infect Dis. 2019 Jun 19;220(2):316-320. doi: 10.1093/infdis/jiz104.

7.

GUILDify v2.0: A Tool to Identify Molecular Networks Underlying Human Diseases, Their Comorbidities and Their Druggable Targets.

Aguirre-Plans J, Piñero J, Sanz F, Furlong LI, Fernandez-Fuentes N, Oliva B, Guney E.

J Mol Biol. 2019 Jun 14;431(13):2477-2484. doi: 10.1016/j.jmb.2019.02.027. Epub 2019 Mar 7.

PMID:
30851278
8.

A multicenter retrospective study on cryopreserved amniotic membrane transplantation for the treatment of complicated corneal ulcers in the dog.

Costa D, Leiva M, Sanz F, Espejo V, Esteban J, Vergara J, Díaz C, Huguet E, Cairó M, Ríos J, Peña MT.

Vet Ophthalmol. 2019 Sep;22(5):695-702. doi: 10.1111/vop.12643. Epub 2019 Feb 4.

PMID:
30716187
9.

Correction: Pulling lipid tubes from supported bilayers unveils the underlying substrate contribution to the membrane mechanics.

Gumí-Audenis B, Costa L, Ferrer-Tasies L, Ratera I, Ventosa N, Sanz F, Giannotti MI.

Nanoscale. 2018 Dec 28;10(48):23199. doi: 10.1039/c8nr90267d. Epub 2018 Dec 5.

PMID:
30516221
10.

Insights into the structure and nanomechanics of a quatsome membrane by force spectroscopy measurements and molecular simulations.

Gumí-Audenis B, Illa-Tuset S, Grimaldi N, Pasquina-Lemonche L, Ferrer-Tasies L, Sanz F, Veciana J, Ratera I, Faraudo J, Ventosa N, Giannotti MI.

Nanoscale. 2018 Dec 13;10(48):23001-23011. doi: 10.1039/c8nr07110a.

PMID:
30500043
11.

Development of an Infrastructure for the Prediction of Biological Endpoints in Industrial Environments. Lessons Learned at the eTOX Project.

Pastor M, Quintana J, Sanz F.

Front Pharmacol. 2018 Oct 11;9:1147. doi: 10.3389/fphar.2018.01147. eCollection 2018.

12.

The BIOMEPOC Project: Personalized Biomarkers and Clinical Profiles in Chronic Obstructive Pulmonary Disease.

Gea J, Pascual S, Castro-Acosta A, Hernández-Carcereny C, Castelo R, Márquez-Martín E, Montón C, Palou A, Faner R, Furlong LI, Seijo L, Sanz F, Torà M, Vilaplana C, Casadevall C, López-Campos JL, Monsó E, Peces-Barba G, Cosío BG, Agustí A; en representación del grupo BIOMEPOC; Anexo. Miembros del grupo BIOMEPOC.

Arch Bronconeumol. 2019 Feb;55(2):93-99. doi: 10.1016/j.arbres.2018.07.026. Epub 2018 Oct 19. English, Spanish.

13.

Network, Transcriptomic and Genomic Features Differentiate Genes Relevant for Drug Response.

Piñero J, Gonzalez-Perez A, Guney E, Aguirre-Plans J, Sanz F, Oliva B, Furlong LI.

Front Genet. 2018 Sep 25;9:412. doi: 10.3389/fgene.2018.00412. eCollection 2018.

14.

Casein interaction with lipid membranes: Are the phase state or charge density of the phospholipids affecting protein adsorption?

Crespo-Villanueva A, Gumí-Audenis B, Sanz F, Artzner F, Mériadec C, Rousseau F, Lopez C, Giannotti MI, Guyomarc'h F.

Biochim Biophys Acta Biomembr. 2018 Dec;1860(12):2588-2598. doi: 10.1016/j.bbamem.2018.09.016. Epub 2018 Sep 28.

15.

In silico models in drug development: where we are.

Piñero J, Furlong LI, Sanz F.

Curr Opin Pharmacol. 2018 Oct;42:111-121. doi: 10.1016/j.coph.2018.08.007. Epub 2018 Sep 8. Review.

PMID:
30205360
16.

Adaptation of antibiotic treatment to clinical practice guidelines in patients aged ⩾65 years hospitalised due to community-acquired pneumonia.

Fernandez-Sierra MA, Rueda-Domingo MT, Rodriguez-Del-Aguila MM, Perez-Lozano MJ, Force L, Fernandez-Villa T, Astray J, Egurrola M, Castilla J, Sanz F, Toledo D, Dominguez A; Workgroup Project PI12/02079.

Epidemiol Infect. 2018 Oct;146(14):1870-1877. doi: 10.1017/S0950268818002121. Epub 2018 Aug 2.

PMID:
30070190
17.

Cbt modulates Foxo activation by positively regulating insulin signaling in Drosophila embryos.

Muñoz-Soriano V, Belacortu Y, Sanz FJ, Solana-Manrique C, Dillon L, Suay-Corredera C, Ruiz-Romero M, Corominas M, Paricio N.

Biochim Biophys Acta Gene Regul Mech. 2018 Jul 26. pii: S1874-9399(18)30034-8. doi: 10.1016/j.bbagrm.2018.07.010. [Epub ahead of print]

PMID:
30055320
18.

Pulling lipid tubes from supported bilayers unveils the underlying substrate contribution to the membrane mechanics.

Gumí-Audenis B, Costa L, Ferrer-Tasies L, Ratera I, Ventosa N, Sanz F, Giannotti MI.

Nanoscale. 2018 Aug 2;10(30):14763-14770. doi: 10.1039/c8nr03249a. Erratum in: Nanoscale. 2018 Dec 28;10(48):23199.

19.

A Retrospective Cross-Sectional Population-Based Study on Prenatal Levels of Adherence to the Mediterranean Diet: Maternal Profile and Effects on the Newborn.

Peraita-Costa I, Llopis-González A, Perales-Marín A, Sanz F, Llopis-Morales A, Morales-Suárez-Varela M.

Int J Environ Res Public Health. 2018 Jul 19;15(7). pii: E1530. doi: 10.3390/ijerph15071530.

20.

Hepatotoxicity Prediction by Systems Biology Modeling of Disturbed Metabolic Pathways Using Gene Expression Data.

López-Massaguer O, Pastor M, Sanz F, Carbonell P.

Methods Mol Biol. 2018;1800:505-518. doi: 10.1007/978-1-4939-7899-1_23.

PMID:
29934908
21.

Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology.

Aguirre-Plans J, Piñero J, Menche J, Sanz F, Furlong LI, Schmidt HHHW, Oliva B, Guney E.

Pharmaceuticals (Basel). 2018 Jun 22;11(3). pii: E61. doi: 10.3390/ph11030061.

22.

comoRbidity: an R package for the systematic analysis of disease comorbidities.

Gutiérrez-Sacristán A, Bravo À, Giannoula A, Mayer MA, Sanz F, Furlong LI.

Bioinformatics. 2018 Sep 15;34(18):3228-3230. doi: 10.1093/bioinformatics/bty315.

23.

In Silico QT and APD Prolongation Assay for Early Screening of Drug-Induced Proarrhythmic Risk.

Romero L, Cano J, Gomis-Tena J, Trenor B, Sanz F, Pastor M, Saiz J.

J Chem Inf Model. 2018 Apr 23;58(4):867-878. doi: 10.1021/acs.jcim.7b00440. Epub 2018 Mar 16.

24.

Identifying temporal patterns in patient disease trajectories using dynamic time warping: A population-based study.

Giannoula A, Gutierrez-Sacristán A, Bravo Á, Sanz F, Furlong LI.

Sci Rep. 2018 Mar 9;8(1):4216. doi: 10.1038/s41598-018-22578-1.

25.

Diastereoselective synthesis of chiral 1,3-cyclohexadienals.

Urosa A, Tobal IE, de la Granja ÁP, Capitán MC, Moro RF, Marcos IS, Garrido NM, Sanz F, Calle E, Díez D.

PLoS One. 2018 Feb 13;13(2):e0192113. doi: 10.1371/journal.pone.0192113. eCollection 2018.

26.

A Composite of Functional Status and Pneumonia Severity Index Improves the Prediction of Pneumonia Mortality in Older Patients.

Sanz F, Morales-Suárez-Varela M, Fernández E, Force L, Pérez-Lozano MJ, Martín V, Egurrola M, Castilla J, Astray J, Toledo D, Domínguez Á; Project PI12/02079 Working Group.

J Gen Intern Med. 2018 Apr;33(4):437-444. doi: 10.1007/s11606-017-4267-8. Epub 2018 Jan 4.

27.

Text mining and expert curation to develop a database on psychiatric diseases and their genes.

Gutiérrez-Sacristán A, Bravo À, Portero-Tresserra M, Valverde O, Armario A, Blanco-Gandía MC, Farré A, Fernández-Ibarrondo L, Fonseca F, Giraldo J, Leis A, Mané A, Mayer MA, Montagud-Romero S, Nadal R, Ortiz J, Pavon FJ, Perez EJ, Rodríguez-Arias M, Serrano A, Torrens M, Warnault V, Sanz F, Furlong LI.

Database (Oxford). 2017 Jan 1;2017. doi: 10.1093/database/bax043.

28.

In-plane molecular organization of hydrated single lipid bilayers: DPPC:cholesterol.

Gumí-Audenis B, Costa L, Redondo-Morata L, Milhiet PE, Sanz F, Felici R, Giannotti MI, Carlà F.

Nanoscale. 2017 Dec 21;10(1):87-92. doi: 10.1039/c7nr07510c.

PMID:
29210438
29.

Generating Modeling Data From Repeat-Dose Toxicity Reports.

López-Massaguer O, Pinto-Gil K, Sanz F, Amberg A, Anger LT, Stolte M, Ravagli C, Marc P, Pastor M.

Toxicol Sci. 2018 Mar 1;162(1):287-300. doi: 10.1093/toxsci/kfx254.

30.

Adverse outcome pathways: opportunities, limitations and open questions.

Leist M, Ghallab A, Graepel R, Marchan R, Hassan R, Bennekou SH, Limonciel A, Vinken M, Schildknecht S, Waldmann T, Danen E, van Ravenzwaay B, Kamp H, Gardner I, Godoy P, Bois FY, Braeuning A, Reif R, Oesch F, Drasdo D, Höhme S, Schwarz M, Hartung T, Braunbeck T, Beltman J, Vrieling H, Sanz F, Forsby A, Gadaleta D, Fisher C, Kelm J, Fluri D, Ecker G, Zdrazil B, Terron A, Jennings P, van der Burg B, Dooley S, Meijer AH, Willighagen E, Martens M, Evelo C, Mombelli E, Taboureau O, Mantovani A, Hardy B, Koch B, Escher S, van Thriel C, Cadenas C, Kroese D, van de Water B, Hengstler JG.

Arch Toxicol. 2017 Nov;91(11):3477-3505. doi: 10.1007/s00204-017-2045-3. Epub 2017 Oct 19. Review.

PMID:
29051992
31.

Legacy data sharing to improve drug safety assessment: the eTOX project.

Sanz F, Pognan F, Steger-Hartmann T, Díaz C; eTOX, Cases M, Pastor M, Marc P, Wichard J, Briggs K, Watson DK, Kleinöder T, Yang C, Amberg A, Beaumont M, Brookes AJ, Brunak S, Cronin MTD, Ecker GF, Escher S, Greene N, Guzmán A, Hersey A, Jacques P, Lammens L, Mestres J, Muster W, Northeved H, Pinches M, Saiz J, Sajot N, Valencia A, van der Lei J, Vermeulen NPE, Vock E, Wolber G, Zamora I.

Nat Rev Drug Discov. 2017 Dec;16(12):811-812. doi: 10.1038/nrd.2017.177. Epub 2017 Oct 13.

PMID:
29026211
32.

An automated tool for obtaining QSAR-ready series of compounds using semantic web technologies.

López-Massaguer O, Sanz F, Pastor M.

Bioinformatics. 2018 Jan 1;34(1):131-133. doi: 10.1093/bioinformatics/btx566.

PMID:
28968713
33.

Outpatient vaginal hysterectomy: Comparison of conventional suture ligature versus electrosurgical bipolar vessel sealing.

Giraudet G, Lucot JP, Sanz F, Rubod C, Collinet P, Cosson M.

J Gynecol Obstet Hum Reprod. 2017 May;46(5):399-404. doi: 10.1016/j.jogoh.2017.03.007. Epub 2017 Mar 31.

PMID:
28934083
34.

Four simple recommendations to encourage best practices in research software.

Jiménez RC, Kuzak M, Alhamdoosh M, Barker M, Batut B, Borg M, Capella-Gutierrez S, Chue Hong N, Cook M, Corpas M, Flannery M, Garcia L, Gelpí JL, Gladman S, Goble C, González Ferreiro M, Gonzalez-Beltran A, Griffin PC, Grüning B, Hagberg J, Holub P, Hooft R, Ison J, Katz DS, Leskošek B, López Gómez F, Oliveira LJ, Mellor D, Mosbergen R, Mulder N, Perez-Riverol Y, Pergl R, Pichler H, Pope B, Sanz F, Schneider MV, Stodden V, Suchecki R, Svobodová Vařeková R, Talvik HA, Todorov I, Treloar A, Tyagi S, van Gompel M, Vaughan D, Via A, Wang X, Watson-Haigh NS, Crouch S.

F1000Res. 2017 Jun 13;6. pii: ELIXIR-876. doi: 10.12688/f1000research.11407.1. eCollection 2017.

35.

Genetic and functional characterization of disease associations explains comorbidity.

Rubio-Perez C, Guney E, Aguilar D, Piñero J, Garcia-Garcia J, Iadarola B, Sanz F, Fernandez-Fuentes N, Furlong LI, Oliva B.

Sci Rep. 2017 Jul 24;7(1):6207. doi: 10.1038/s41598-017-04939-4.

36.

Differential Electrochemical Conductance Imaging at the Nanoscale.

López-Martínez M, Artés JM, Sarasso V, Carminati M, Díez-Pérez I, Sanz F, Gorostiza P.

Small. 2017 Sep;13(36). doi: 10.1002/smll.201700958. Epub 2017 Jul 19.

PMID:
28722303
37.

High endocan levels are associated with the need for mechanical ventilation among patients with severe sepsis.

Mangat M, Amalakuhan B, Habib S, Reyes LF, Hinojosa CA, Rodriguez AH, Soni NJ, Anzueto A, Levine SM, Peters JI, Aliberti S, Sibila O, Rello J, Witzenrath M, Waterer GW, Martin-Loeches I, Blanquer J, Sanz F, Marcos PJ, Solé-Violán J, Chalmers JD, Feldman C, Wunderink RG, Cruz CSD, Orihuela CJ, Restrepo MI.

Eur Respir J. 2017 Jul 5;50(1). pii: 1700013. doi: 10.1183/13993003.00013-2017. Print 2017 Jul. No abstract available.

38.

Asthma in older people hospitalized with influenza in Spain: A case-control study.

Morales-Suárez-Varela M, Llopis-González A, Vergara-Hernández C, Fernandez-Fabrellas E, Sanz F, Perez-Lozano MJ, Martin V, Astray J, Castilla J, Egurrola M, Force L, Toledo D, Domínguez À.

Allergy Asthma Proc. 2017 Jul 1;38(4):277-285. doi: 10.2500/aap.2017.38.4060.

PMID:
28668107
39.

Cutaneous Leishmania tropica in children: report of three imported cases successfully treated with liposomal amphotericin B.

Knöpfel N, Noguera-Morel L, Azorin D, Sanz F, Torrelo A, Hernández-Martín A.

J Eur Acad Dermatol Venereol. 2018 Jan;32(1):e8-e10. doi: 10.1111/jdv.14434. Epub 2017 Jul 17. No abstract available.

PMID:
28653351
40.

Asthma and influenza vaccination in elderly hospitalized patients: Matched case-control study in Spain.

Suárez-Varela MM, Llopis A, Fernandez-Fabrellas E, Sanz F, Perez-Lozano MJ, Martin V, Astray J, Castilla J, Egurrola M, Force L, Toledo D, Domínguez À; Working group of project pi12/02079 ‘effectiveness of influenza and pneumococcal polysaccharide 23-valent vaccines in people aged 65 years and more’.

J Asthma. 2018 Apr;55(4):391-401. doi: 10.1080/02770903.2017.1332204. Epub 2017 Jun 21.

PMID:
28636411
41.

Identification of potential therapeutic compounds for Parkinson's disease using Drosophila and human cell models.

Sanz FJ, Solana-Manrique C, Muñoz-Soriano V, Calap-Quintana P, Moltó MD, Paricio N.

Free Radic Biol Med. 2017 Jul;108:683-691. doi: 10.1016/j.freeradbiomed.2017.04.364. Epub 2017 Apr 25.

PMID:
28455141
42.

Crystal structure of methyl (4R)-4-(4-meth-oxy-benzo-yl)-4-{[(1R)-1-phenyl-eth-yl]carbamo-yl}butano-ate.

Manchado A, Salgado MM, Vicente Á, Díez D, Sanz F, Garrido NM.

Acta Crystallogr E Crystallogr Commun. 2017 Mar 14;73(Pt 4):503-506. doi: 10.1107/S2056989017003607. eCollection 2017 Apr 1.

43.

Using Electronic Health Records to Assess Depression and Cancer Comorbidities.

Mayer MA, Gutierrez-Sacristan A, Leis A, De La Peña S, Sanz F, Furlong LI.

Stud Health Technol Inform. 2017;235:236-240.

PMID:
28423789
44.

Single-molecule electrical contacts on silicon electrodes under ambient conditions.

Aragonès AC, Darwish N, Ciampi S, Sanz F, Gooding JJ, Díez-Pérez I.

Nat Commun. 2017 Apr 13;8:15056. doi: 10.1038/ncomms15056.

45.

Membrane cholesterol access into a G-protein-coupled receptor.

Guixà-González R, Albasanz JL, Rodriguez-Espigares I, Pastor M, Sanz F, Martí-Solano M, Manna M, Martinez-Seara H, Hildebrand PW, Martín M, Selent J.

Nat Commun. 2017 Feb 21;8:14505. doi: 10.1038/ncomms14505.

46.

Metal-Controlled Magnetoresistance at Room Temperature in Single-Molecule Devices.

Aragonès AC, Aravena D, Valverde-Muñoz FJ, Real JA, Sanz F, Díez-Pérez I, Ruiz E.

J Am Chem Soc. 2017 Apr 26;139(16):5768-5778. doi: 10.1021/jacs.6b11166. Epub 2017 Mar 3.

PMID:
28215074
47.

Effectiveness of 23-valent pneumococcal polysaccharide vaccination in preventing community-acquired pneumonia hospitalization and severe outcomes in the elderly in Spain.

Domínguez À, Soldevila N, Toledo D, Torner N, Force L, Pérez MJ, Martín V, Rodríguez-Rojas L, Astray J, Egurrola M, Sanz F, Castilla J; Working Group of the Project PI12/02079.

PLoS One. 2017 Feb 10;12(2):e0171943. doi: 10.1371/journal.pone.0171943. eCollection 2017.

48.

Crystal structure of (2R*,3aR*)-2-phenyl-sulfonyl-2,3,3a,4,5,6-hexa-hydro-pyrrolo-[1,2-b]isoxazole.

Hernández Y, Marcos I, Garrido NM, Sanz F, Diez D.

Acta Crystallogr E Crystallogr Commun. 2017 Jan 1;73(Pt 1):85-87. doi: 10.1107/S2056989016019952. eCollection 2017 Jan 1.

49.

Structure and Nanomechanics of Model Membranes by Atomic Force Microscopy and Spectroscopy: Insights into the Role of Cholesterol and Sphingolipids.

Gumí-Audenis B, Costa L, Carlá F, Comin F, Sanz F, Giannotti MI.

Membranes (Basel). 2016 Dec 19;6(4). pii: E58. doi: 10.3390/membranes6040058. Review.

50.

A molecular receptor selective for zwitterionic alanine.

Rubio OH, Taouil R, Muñiz FM, Monleón LM, Simón L, Sanz F, Morán JR.

Org Biomol Chem. 2017 Jan 4;15(2):477-485. doi: 10.1039/c6ob02237e.

PMID:
27929186

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