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Endothelial cells: The heart attack of the Clones.

Santulli G.

Sci Transl Med. 2018 Feb 7;10(427). pii: eaar7529. doi: 10.1126/scitranslmed.aar7529.


Cardioprotective effects of autophagy: Eat your heart out, heart failure!

Santulli G.

Sci Transl Med. 2018 May 30;10(443). pii: eaau0462. doi: 10.1126/scitranslmed.aau0462.


Update on peripheral artery disease: Epidemiology and evidence-based facts.

Shu J, Santulli G.

Atherosclerosis. 2018 May 22. pii: S0021-9150(18)30276-4. doi: 10.1016/j.atherosclerosis.2018.05.033. [Epub ahead of print] No abstract available.


The Non-Coding RNA Journal Club: Highlights on Recent Papers-5.

Achour C, Bogard B, Hubé F, Mani SA, Santulli G, Taube JH.

Noncoding RNA. 2017 Jun 14;3(2). pii: E21. doi: 10.3390/ncrna3020021.


Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure.

Kushnir A, Santulli G, Reiken SR, Coromilas E, Godfrey SJ, Brunjes DL, Colombo PC, Yuzefpolskaya M, Sokol SI, Kitsis RN, Marks AR.

Circulation. 2018 Mar 28. pii: CIRCULATIONAHA.117.032703. doi: 10.1161/CIRCULATIONAHA.117.032703. [Epub ahead of print]


Dietary fat is a key determinant in balancing mitochondrial dynamics in heart failure: a novel mechanism underlying the obesity paradox.

De Rosa M, Gambardella J, Shu J, Santulli G.

Cardiovasc Res. 2018 Jun 1;114(7):925-927. doi: 10.1093/cvr/cvy074. No abstract available.


The Amino-Terminal Domain of GRK5 Inhibits Cardiac Hypertrophy through the Regulation of Calcium-Calmodulin Dependent Transcription Factors.

Sorriento D, Santulli G, Ciccarelli M, Maione AS, Illario M, Trimarco B, Iaccarino G.

Int J Mol Sci. 2018 Mar 15;19(3). pii: E861. doi: 10.3390/ijms19030861.


Ryanodine Receptor Structure and Function in Health and Disease.

Santulli G, Lewis D, des Georges A, Marks AR, Frank J.

Subcell Biochem. 2018;87:329-352. doi: 10.1007/978-981-10-7757-9_11.


Effectiveness of new generation drug-eluting stents in ostial right coronary artery lesions.

De Rosa M, Santulli G.

Int J Cardiol. 2018 Mar 1;254:84-86. doi: 10.1016/j.ijcard.2017.11.105. Epub 2018 Jan 28. No abstract available.


Sirolimus induces depletion of intracellular calcium stores and mitochondrial dysfunction in pancreatic beta cells.

Lombardi A, Gambardella J, Du XL, Sorriento D, Mauro M, Iaccarino G, Trimarco B, Santulli G.

Sci Rep. 2017 Nov 20;7(1):15823. doi: 10.1038/s41598-017-15283-y.


Impaired mitochondrial calcium uptake caused by tacrolimus underlies beta-cell failure.

Lombardi A, Trimarco B, Iaccarino G, Santulli G.

Cell Commun Signal. 2017 Nov 13;15(1):47. doi: 10.1186/s12964-017-0203-0.


New Insights in Cardiac Calcium Handling and Excitation-Contraction Coupling.

Gambardella J, Trimarco B, Iaccarino G, Santulli G.

Adv Exp Med Biol. 2018;1067:373-385. doi: 10.1007/5584_2017_106.


Opposite effects of β2-adrenoceptor gene deletion on insulin signaling in liver and skeletal muscle.

Cipolletta E, Del Giudice C, Santulli G, Trimarco B, Iaccarino G.

Nutr Metab Cardiovasc Dis. 2017 Jul;27(7):615-623. doi: 10.1016/j.numecd.2017.05.011. Epub 2017 Jun 15.


Physiology and pathophysiology of excitation-contraction coupling: the functional role of ryanodine receptor.

Santulli G, Lewis DR, Marks AR.

J Muscle Res Cell Motil. 2017 Feb;38(1):37-45. doi: 10.1007/s10974-017-9470-z. Epub 2017 Jun 26. Review.


Mechanistic Role of Kinases in the Regulation of Mitochondrial Fitness.

Sorriento D, Gambardella J, Fiordelisi A, Trimarco B, Ciccarelli M, Iaccarino G, Santulli G.

Adv Exp Med Biol. 2017;982:521-528. doi: 10.1007/978-3-319-55330-6_26. Review.


Functional Role of Mitochondria in Arrhythmogenesis.

Gambardella J, Sorriento D, Ciccarelli M, Del Giudice C, Fiordelisi A, Napolitano L, Trimarco B, Iaccarino G, Santulli G.

Adv Exp Med Biol. 2017;982:191-202. doi: 10.1007/978-3-319-55330-6_10. Review.


Intracellular calcium release channels: an update.

Santulli G, Nakashima R, Yuan Q, Marks AR.

J Physiol. 2017 May 15;595(10):3041-3051. doi: 10.1113/JP272781. Review.


Effects of Alpha Lipoic Acid on Multiple Cytokines and Biomarkers and Recurrence of Atrial Fibrillation Within 1 Year of Catheter Ablation.

Sardu C, Santulli G, Santamaria M, Barbieri M, Sacra C, Paolisso P, D'Amico F, Testa N, Caporaso I, Paolisso G, Marfella R, Rizzo MR.

Am J Cardiol. 2017 May 1;119(9):1382-1386. doi: 10.1016/j.amjcard.2017.01.040. Epub 2017 Feb 10.


Quit smoking to outsmart atherogenesis: Molecular mechanisms underlying clinical evidence.

Gambardella J, Sardu C, Sacra C, Del Giudice C, Santulli G.

Atherosclerosis. 2017 Feb;257:242-245. doi: 10.1016/j.atherosclerosis.2016.12.010. Epub 2016 Dec 16. No abstract available.


Childhood obesity and education.

Santulli G.

Lancet Diabetes Endocrinol. 2016 Nov;4(11):957. doi: 10.1016/S2213-8587(15)00517-3. Epub 2016 Feb 24. Review. No abstract available.


Erratum: The Non-Coding RNA Journal Club: Highlights on Recent Papers-4. Non-Coding RNA 2016, 2, 9.

Gautheret D, Taube JH, Mani SA, Santulli G, Cuerda-Gil D, Slotkin RK, Zhang B, Wang Y, Salzman DW, Weidhaas JB.

Noncoding RNA. 2016 Sep 30;2(4). pii: E10. doi: 10.3390/ncrna2040010.


The Non-Coding RNA Journal Club: Highlights on Recent Papers-4.

Gautheret D, Taube JH, Mani SA, Santulli G, Cuerda-Gil D, Slotkin RK, Zhang B, Wang Y, Salzman DW, Weidhaas JB.

Noncoding RNA. 2016 Sep 21;2(3). pii: E9. doi: 10.3390/ncrna2030009.


Integrating diet and inflammation to calculate cardiovascular risk.

Gambardella J, Santulli G.

Atherosclerosis. 2016 Oct;253:258-261. doi: 10.1016/j.atherosclerosis.2016.08.041. Epub 2016 Aug 28. No abstract available.


Leaky ryanodine receptors contribute to diaphragmatic weakness during mechanical ventilation.

Matecki S, Dridi H, Jung B, Saint N, Reiken SR, Scheuermann V, Mrozek S, Santulli G, Umanskaya A, Petrof BJ, Jaber S, Marks AR, Lacampagne A.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):9069-74. doi: 10.1073/pnas.1609707113. Epub 2016 Jul 25.


Maintenance of normal blood pressure is dependent on IP3R1-mediated regulation of eNOS.

Yuan Q, Yang J, Santulli G, Reiken SR, Wronska A, Kim MM, Osborne BW, Lacampagne A, Yin Y, Marks AR.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):8532-7. doi: 10.1073/pnas.1608859113. Epub 2016 Jul 8.


Telemonitoring in heart failure patients treated by cardiac resynchronisation therapy with defibrillator (CRT-D): the TELECART Study.

Sardu C, Santamaria M, Rizzo MR, Barbieri M, di Marino M, Paolisso G, Santulli G, Marfella R.

Int J Clin Pract. 2016 Jul;70(7):569-76. doi: 10.1111/ijcp.12823. Epub 2016 Jun 13.


Adrenergic signaling in heart failure and cardiovascular aging.

Santulli G, Iaccarino G.

Maturitas. 2016 Nov;93:65-72. doi: 10.1016/j.maturitas.2016.03.022. Epub 2016 Mar 26. Review.


Models for preclinical studies in aging-related disorders: One is not for all.

Santulli G, Borras C, Bousquet J, Calzà L, Cano A, Illario M, Franceschi C, Liotta G, Maggio M, Molloy WD, Montuori N, O'Caoimh R, Orfila F, Rauter AP, Santoro A, Iaccarino G.

Transl Med UniSa. 2016 Jan 31;13:4-12. eCollection 2015 Dec.


The possible role of chromosome X variability in hypertensive familiarity.

Ciccarelli M, Finelli R, Rivera N, Santulli G, Izzo R, De Luca N, Rozza F, Ceccarelli M, Pagnotta S, Uliano F, Tremigliozzi R, Condorelli G, Trimarco V, Iaccarino G.

J Hum Hypertens. 2017 Jan;31(1):37-42. doi: 10.1038/jhh.2016.9. Epub 2016 Feb 25.


Imprints of multiple glacial refugia in the Pyrenees revealed by phylogeography and palaeodistribution modelling of an endemic spider.

Bidegaray-Batista L, Sánchez-Gracia A, Santulli G, Maiorano L, Guisan A, Vogler AP, Arnedo MA.

Mol Ecol. 2016 May;25(9):2046-64. doi: 10.1111/mec.13585. Epub 2016 Mar 28.


Exploiting microRNA Specificity and Selectivity: Paving a Sustainable Path Towards Precision Medicine.

Santulli G.

Adv Exp Med Biol. 2015;888:1-3. doi: 10.1007/978-3-319-22671-2_1.


Mechanistic Role of MicroRNAs in Coupling Lipid Metabolism and Atherosclerosis.

Novák J, Olejníčková V, Tkáčová N, Santulli G.

Adv Exp Med Biol. 2015;887:79-100. doi: 10.1007/978-3-319-22380-3_5. Erratum in: Adv Exp Med Biol. 2015;888:E1-2.


A Fleeting Glimpse Inside microRNA, Epigenetics, and Micropeptidomics.

Santulli G.

Adv Exp Med Biol. 2015;887:1-14. doi: 10.1007/978-3-319-22380-3_1.


MicroRNAs and Endothelial (Dys) Function.

Santulli G.

J Cell Physiol. 2016 Aug;231(8):1638-44. doi: 10.1002/jcp.25276. Epub 2015 Dec 30. Review.


Calcium release channel RyR2 regulates insulin release and glucose homeostasis.

Santulli G, Pagano G, Sardu C, Xie W, Reiken S, D'Ascia SL, Cannone M, Marziliano N, Trimarco B, Guise TA, Lacampagne A, Marks AR.

J Clin Invest. 2015 Nov 2;125(11):4316. doi: 10.1172/JCI84937. Epub 2015 Nov 2. No abstract available.


Integrating GRK2 and NFkappaB in the Pathophysiology of Cardiac Hypertrophy.

Sorriento D, Santulli G, Franco A, Cipolletta E, Napolitano L, Gambardella J, Gomez-Monterrey I, Campiglia P, Trimarco B, Iaccarino G, Ciccarelli M.

J Cardiovasc Transl Res. 2015 Nov;8(8):493-502. doi: 10.1007/s12265-015-9646-0. Epub 2015 Jul 30.


Mitochondrial calcium overload is a key determinant in heart failure.

Santulli G, Xie W, Reiken SR, Marks AR.

Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11389-94. doi: 10.1073/pnas.1513047112. Epub 2015 Jul 27.


Mitochondrial oxidative stress promotes atrial fibrillation.

Xie W, Santulli G, Reiken SR, Yuan Q, Osborne BW, Chen BX, Marks AR.

Sci Rep. 2015 Jul 14;5:11427. doi: 10.1038/srep11427.


Targeting the CaMKII/ERK Interaction in the Heart Prevents Cardiac Hypertrophy.

Cipolletta E, Rusciano MR, Maione AS, Santulli G, Sorriento D, Del Giudice C, Ciccarelli M, Franco A, Crola C, Campiglia P, Sala M, Gomez-Monterrey I, De Luca N, Trimarco B, Iaccarino G, Illario M.

PLoS One. 2015 Jun 25;10(6):e0130477. doi: 10.1371/journal.pone.0130477. eCollection 2015.


Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

Santulli G, Marks AR.

Curr Mol Pharmacol. 2015;8(2):206-22. Review.


Calcium release channel RyR2 regulates insulin release and glucose homeostasis.

Santulli G, Pagano G, Sardu C, Xie W, Reiken S, D'Ascia SL, Cannone M, Marziliano N, Trimarco B, Guise TA, Lacampagne A, Marks AR.

J Clin Invest. 2015 May;125(5):1968-78. doi: 10.1172/JCI79273. Epub 2015 Apr 6. Erratum in: J Clin Invest. 2015 Nov 2;125(11):4316.


β-Blockers in diabetic patients with heart failure.

Santulli G.

JAMA Intern Med. 2015 Apr;175(4):657. doi: 10.1001/jamainternmed.2014.8009. No abstract available.


Effects of low-carbohydrate and low-fat diets.

Santulli G.

Ann Intern Med. 2015 Mar 3;162(5):392. doi: 10.7326/L15-5057-3. No abstract available.



Santulli G.

Adv Exp Med Biol. 2015;889:E1. doi: 10.1007/978-3-319-23730-5_12. No abstract available.


This book represents one volume--focused on biology and basic science. Introduction.

Santulli G.

Adv Exp Med Biol. 2015;887:v-vi. No abstract available.


Functional role of Calstabin2 in age-related cardiac alterations.

Yuan Q, Chen Z, Santulli G, Gu L, Yang ZG, Yuan ZQ, Zhao YT, Xin HB, Deng KY, Wang SQ, Ji G.

Sci Rep. 2014 Dec 11;4:7425. doi: 10.1038/srep07425.


Metabolic syndrome is associated with a poor outcome in patients affected by outflow tract premature ventricular contractions treated by catheter ablation.

Sardu C, Carreras G, Katsanos S, Kamperidis V, Pace MC, Passavanti MB, Fava I, Paolisso P, Pieretti G, Nicoletti GF, Santulli G, Paolisso G, Marfella R.

BMC Cardiovasc Disord. 2014 Dec 6;14:176. doi: 10.1186/1471-2261-14-176.


Application of microRNAs in diagnosis and treatment of cardiovascular disease.

Wronska A, Kurkowska-Jastrzebska I, Santulli G.

Acta Physiol (Oxf). 2015 Jan;213(1):60-83. doi: 10.1111/apha.12416. Epub 2014 Nov 24. Review.


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