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Items: 23


Insect midgut structures and molecules as targets of plant-derived protease inhibitors and lectins.

Napoleão TH, Albuquerque LP, Santos ND, Nova IC, Lima TA, Paiva PM, Pontual EV.

Pest Manag Sci. 2019 May;75(5):1212-1222. doi: 10.1002/ps.5233. Epub 2018 Nov 16. Review.


Histone Deacetylase Inhibitors Synergize with Catalytic Inhibitors of EZH2 to Exhibit Antitumor Activity in Small Cell Carcinoma of the Ovary, Hypercalcemic Type.

Wang Y, Chen SY, Colborne S, Lambert G, Shin CY, Santos ND, Orlando KA, Lang JD, Hendricks WPD, Bally MB, Karnezis AN, Hass R, Underhill TM, Morin GB, Trent JM, Weissman BE, Huntsman DG.

Mol Cancer Ther. 2018 Dec;17(12):2767-2779. doi: 10.1158/1535-7163.MCT-18-0348. Epub 2018 Sep 19.


Antimicrobial potential of Alpinia purpurata lectin (ApuL): Growth inhibitory action, synergistic effects in combination with antibiotics, and antibiofilm activity.

Ferreira GRS, Brito JS, Procópio TF, Santos NDL, de Lima BJRC, Coelho LCBB, Navarro DMDAF, Paiva PMG, Soares T, de Moura MC, Napoleão TH.

Microb Pathog. 2018 Nov;124:152-162. doi: 10.1016/j.micpath.2018.08.027. Epub 2018 Aug 22.


Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma.

Lazzari E, Mondala PK, Santos ND, Miller AC, Pineda G, Jiang Q, Leu H, Ali SA, Ganesan AP, Wu CN, Costello C, Minden M, Chiaramonte R, Stewart AK, Crews LA, Jamieson CHM.

Nat Commun. 2017 Dec 4;8(1):1922. doi: 10.1038/s41467-017-01890-w.


Elucidation of Renal Scars in Children With Vesicoureteral Reflux Using Contrast-Enhanced Ultrasound: A Pilot Study.

Hains DS, Cohen HL, McCarville MB, Ellison EE, Huffman A, Glass S, Qureshi AH, Pierce KR, Cahill AL, Dixon A, Santos ND.

Kidney Int Rep. 2017 Jan 26;2(3):420-424. doi: 10.1016/j.ekir.2017.01.008. eCollection 2017 May.


Effect of Community ART Groups on retention-in-care among patients on ART in Tete Province, Mozambique: a cohort study.

Decroo T, Telfer B, Dores CD, White RA, Santos ND, Mkwamba A, Dezembro S, Joffrisse M, Ellman T, Metcalf C.

BMJ Open. 2017 Aug 11;7(8):e016800. doi: 10.1136/bmjopen-2017-016800.


The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type.

Wang Y, Chen SY, Karnezis AN, Colborne S, Santos ND, Lang JD, Hendricks WP, Orlando KA, Yap D, Kommoss F, Bally MB, Morin GB, Trent JM, Weissman BE, Huntsman DG.

J Pathol. 2017 Jul;242(3):371-383. doi: 10.1002/path.4912. Epub 2017 Jun 2.


CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.

Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O'Neil NJ, Santos ND, Silvester J, Wei V, Garcia J, Kabeer F, Lai D, Soriano P, Banáth J, Chiu DS, Yap D, Le DD, Ye FB, Zhang A, Thu K, Soong J, Lin SC, Tsai AH, Osako T, Algara T, Saunders DN, Wong J, Xian J, Bally MB, Brenton JD, Brown GW, Shah SP, Cescon D, Mak TW, Caldas C, Stirling PC, Hieter P, Balasubramanian S, Aparicio S.

Nat Commun. 2017 Feb 17;8:14432. doi: 10.1038/ncomms14432.


Comprehensive renal function evaluation in patients treated for synchronous bilateral Wilms tumor.

Interiano RB, McCarville MB, Santos ND, Mao S, Wu J, Dome JS, Kieran K, Williams MA, Brennan RC, Krasin MJ, Green DM, Davidoff AM.

J Pediatr Surg. 2017 Jan;52(1):98-103. doi: 10.1016/j.jpedsurg.2016.10.027. Epub 2016 Oct 27.


Chemical characteristics of a heteropolysaccharide from Tylopilus ballouii mushroom and its antioxidant and anti-inflammatory activities.

Lima AT, Santos MN, de Souza LA, Pinheiro TS, Paiva AA, Dore CM, Costa MS, Santos ND, Baseia YG, Araújo RM, Leite EL.

Carbohydr Polym. 2016 Jun 25;144:400-9. doi: 10.1016/j.carbpol.2016.02.050. Epub 2016 Feb 26.


Irinophore C™, a lipid nanoparticle formulation of irinotecan, abrogates the gastrointestinal effects of irinotecan in a rat model of clinical toxicities.

Waterhouse DN, Sutherland BW, Santos ND, Masin D, Osooly M, Strutt D, Ostlund C, Anantha M, Harasym N, Manisali I, Wehbe M, Bally MB, Webb MS.

Invest New Drugs. 2014 Dec;32(6):1071-82. doi: 10.1007/s10637-014-0138-x. Epub 2014 Jul 27.


Harnessing the potential of lipid-based nanomedicines for type-specific ovarian cancer treatments.

Leung AW, Kalra J, Santos ND, Bally MB, Anglesio MS.

Nanomedicine (Lond). 2014 Mar;9(3):501-22. doi: 10.2217/nnm.13.220. Review.


Evaluation of Moringa oleifera seed lectin in traps for the capture of Aedes aegypti eggs and adults under semi-field conditions.

Santos ND, Paixão Kda S, Napoleão TH, Trindade PB, Pinto MR, Coelho LC, Eiras ÁE, Navarro DM, Paiva PM.

Parasitol Res. 2014 May;113(5):1837-42. doi: 10.1007/s00436-014-3830-z. Epub 2014 Mar 7.


Effect of Moringa oleifera lectins on survival and enzyme activities of Aedes aegypti larvae susceptible and resistant to organophosphate.

Agra-Neto AC, Napoleão TH, Pontual EV, Santos ND, Luz Lde A, de Oliveira CM, de Melo-Santos MA, Coelho LC, Navarro DM, Paiva PM.

Parasitol Res. 2014 Jan;113(1):175-84. doi: 10.1007/s00436-013-3640-8. Epub 2013 Oct 19.


Antiangiogenic activity and direct antitumor effect from a sulfated polysaccharide isolated from seaweed.

Guerra Dore CM, Faustino Alves MG, Santos ND, Cruz AK, Câmara RB, Castro AJ, Guimarães Alves L, Nader HB, Leite EL.

Microvasc Res. 2013 Jul;88:12-8. doi: 10.1016/j.mvr.2013.03.001. Epub 2013 Mar 16.


Influence of the 48867A>C (Asp358Ala) IL6R polymorphism on response to a lifestyle modification intervention in individuals with metabolic syndrome.

Vargas VR, Bonatto SL, Macagnan FE, Feoli AM, Alho CS, Santos ND, Schmitt VM.

Genet Mol Res. 2013 Feb 28;12(3):3983-91. doi: 10.4238/2013.February.28.8.


Oviposition-stimulant and ovicidal activities of Moringa oleifera lectin on Aedes aegypti.

Santos ND, de Moura KS, Napoleão TH, Santos GK, Coelho LC, Navarro DM, Paiva PM.

PLoS One. 2012;7(9):e44840. doi: 10.1371/journal.pone.0044840. Epub 2012 Sep 6.


Antioxidant and anti-inflammatory effect of polysaccharides from Lobophora variegata on zymosan-induced arthritis in rats.

Paiva AA, Castro AJ, Nascimento MS, Will LS, Santos ND, Araújo RM, Xavier CA, Rocha FA, Leite EL.

Int Immunopharmacol. 2011 Sep;11(9):1241-50. doi: 10.1016/j.intimp.2011.04.003. Epub 2011 Apr 17.


Effect of Moringa oleifera lectin on development and mortality of Aedes aegypti larvae.

Coelho JS, Santos ND, Napoleão TH, Gomes FS, Ferreira RS, Zingali RB, Coelho LC, Leite SP, Navarro DM, Paiva PM.

Chemosphere. 2009 Nov;77(7):934-8. doi: 10.1016/j.chemosphere.2009.08.022. Epub 2009 Sep 10.


[Imaginaries present in the training of health professionals in Brazil and the horizons of supplementary care regulation].

Ceccim RB, Armani TB, de Oliveira DL, Bilibio LF, Moraes M, Santos ND.

Cien Saude Colet. 2008 Sep-Oct;13(5):1567-78. Portuguese.


Larvicidal activity of lectins from Myracrodruon urundeuva on Aedes aegypti.

Sá RA, Santos ND, da Silva CS, Napoleão TH, Gomes FS, Cavada BS, Coelho LC, Navarro DM, Bieber LW, Paiva PM.

Comp Biochem Physiol C Toxicol Pharmacol. 2009 Apr;149(3):300-6. doi: 10.1016/j.cbpc.2008.08.004. Epub 2008 Aug 15.


Urokinase-type Plasminogen Activator (uPA) is Inhibited with QLT0267 a Small Molecule Targeting Integrin-linked Kinase (ILK).

Santos ND, Habibi G, Wang M, Law JH, Andrews HN, Wei D, Triche T, Dedhar S, Dunn SE.

Transl Oncogenomics. 2007 Jul 23;2:85-97. Print 2007.


Strict red blood cell transfusion guideline reduces the need for transfusions in very-low-birthweight infants in the first 4 weeks of life: a multicentre trial.

Miyashiro AM, Santos Nd, Guinsburg R, Kopelman BI, Peres Cde A, Taga MF, Shinzato AR, Costa Hde P.

Vox Sang. 2005 Feb;88(2):107-13.


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