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Items: 1 to 50 of 93

1.

DGCR2 influences cortical thickness through a mechanism independent of schizophrenia pathogenesis.

Belangero SI, Ota VK, Gadelha A, Berberian AA, Assunção-Leme IB, Noto C, Christofolini DM, Bellucco FT, Santoro ML, Mazzotti DR, Zugman A, Melaragno MI, Smith MAC, Pellegrino R, Hakonarson H, Cordeiro Q, Moretti PN, Bressan RA, Mari JJ, Jackowski AP.

Psychiatry Res. 2019 Feb 27;274:391-394. doi: 10.1016/j.psychres.2019.02.068. [Epub ahead of print]

PMID:
30901624
2.

Protein disulfide isomerase plasma levels in healthy humans reveal proteomic signatures involved in contrasting endothelial phenotypes.

Oliveira PVS, Garcia-Rosa S, Sachetto ATA, Moretti AIS, Debbas V, De Bessa TC, Silva NT, Pereira ADC, Martins-de-Souza D, Santoro ML, Laurindo FRM.

Redox Biol. 2019 Feb 19;22:101142. doi: 10.1016/j.redox.2019.101142. [Epub ahead of print]

3.

Optimization of von Willebrand factor multimer analysis in vertical mini-gel electrophoresis systems: A rapid procedure.

Thomazini CM, Soares RPS, da Rocha TRF, Sachetto ATA, Santoro ML.

Thromb Res. 2019 Mar;175:76-83. doi: 10.1016/j.thromres.2019.01.018. Epub 2019 Jan 30.

PMID:
30731387
4.

Effects of the interaction between genetic factors and maltreatment on child and adolescent psychiatric disorders.

Carvalho CM, Pan PM, Ota VK, Spindola LM, Xavier G, Santoro ML, Mazzotti DR, Pellegrino R, Hakonarson H, Rohde LA, Miguel EC, Gadelha A, Bressan RA, Belangero SI.

Psychiatry Res. 2019 Jan 29;273:575-577. doi: 10.1016/j.psychres.2019.01.078. [Epub ahead of print]

PMID:
30716596
5.

Comparative study of platelet aggregation and secretion induced by Bothrops jararaca snake venom and thrombin.

Rosa JG, de Albuquerque CZ, Mattaraia VGM, Santoro ML.

Toxicon. 2019 Mar 1;159:50-60. doi: 10.1016/j.toxicon.2019.01.003. Epub 2019 Jan 21.

PMID:
30677414
6.

Downregulation of genes outside the deleted region in individuals with 22q11.2 deletion syndrome.

Dantas AG, Santoro ML, Nunes N, de Mello CB, Pimenta LSE, Meloni VA, Soares DCQ, Belangero SN, Carvalheira G, Kim CA, Melaragno MI.

Hum Genet. 2019 Jan;138(1):93-103. doi: 10.1007/s00439-018-01967-6. Epub 2019 Jan 9.

PMID:
30627818
7.

Acute kidney injury induced by thrombotic microangiopathy in two cases of Bothrops envenomation.

Malaque CMS, Duayer IF, Santoro ML.

Clin Toxicol (Phila). 2018 Nov 15:1-4. doi: 10.1080/15563650.2018.1510129. [Epub ahead of print]

PMID:
30430871
8.

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder.

de Jong S, Diniz MJA, Saloma A, Gadelha A, Santoro ML, Ota VK, Noto C; Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, Curtis C, Newhouse SJ, Patel H, Hall LS, O Reilly PF, Belangero SI, Bressan RA, Breen G.

Commun Biol. 2018 Oct 8;1:163. doi: 10.1038/s42003-018-0155-y. eCollection 2018.

9.

Rutin (quercetin-3-rutinoside) modulates the hemostatic disturbances and redox imbalance induced by Bothrops jararaca snake venom in mice.

Sachetto ATA, Rosa JG, Santoro ML.

PLoS Negl Trop Dis. 2018 Oct 11;12(10):e0006774. doi: 10.1371/journal.pntd.0006774. eCollection 2018 Oct.

10.

Polygenic risk score analyses of symptoms and treatment response in an antipsychotic-naive first episode of psychosis cohort.

Santoro ML, Ota V, de Jong S, Noto C, Spindola LM, Talarico F, Gouvea E, Lee SH, Moretti P, Curtis C, Patel H, Newhouse S, Carvalho CM, Gadelha A, Cordeiro Q, Bressan RA, Belangero SI, Breen G.

Transl Psychiatry. 2018 Aug 31;8(1):174. doi: 10.1038/s41398-018-0230-7.

11.

Polygenic Risk Score for Alzheimer's Disease: Implications for Memory Performance and Hippocampal Volumes in Early Life.

Axelrud LK, Santoro ML, Pine DS, Talarico F, Gadelha A, Manfro GG, Pan PM, Jackowski A, Picon F, Brietzke E, Grassi-Oliveira R, Bressan RA, Miguel EC, Rohde LA, Hakonarson H, Pausova Z, Belangero S, Paus T, Salum GA.

Am J Psychiatry. 2018 Jun 1;175(6):555-563. doi: 10.1176/appi.ajp.2017.17050529. Epub 2018 Mar 2.

12.

Accessing Gene Expression in Treatment-Resistant Schizophrenia.

Moretti PN, Ota VK, Gouvea ES, Pedrini M, Santoro ML, Talarico F, Spindola LM, Carvalho CM, Noto C, Xavier G, Brietzke E, Gadelha A, Bressan R, Mari J, Belangero S.

Mol Neurobiol. 2018 Aug;55(8):7000-7008. doi: 10.1007/s12035-018-0876-4. Epub 2018 Jan 26.

PMID:
29374346
13.

Heavy Environmental Pressure in Campania and Other Italian Regions: A Short Review of Available Evidence.

Mazza A, Piscitelli P, Falco A, Santoro ML, Colangelo M, Imbriani G, Idolo A, De Donno A, Iannuzzi L, Colao A.

Int J Environ Res Public Health. 2018 Jan 10;15(1). pii: E105. doi: 10.3390/ijerph15010105. Review.

14.

Leukocyte telomere length variation in different stages of schizophrenia.

Maurya PK, Rizzo LB, Xavier G, Tempaku PF, Ota VK, Santoro ML, Spíndola LM, Moretti PS, Mazzotti DR, Gadelha A, Gouvea ES, Noto C, Maes M, Cordeiro Q, Bressan RA, Brietzke E, Belangero SI.

J Psychiatr Res. 2018 Jan;96:218-223. doi: 10.1016/j.jpsychires.2017.10.016. Epub 2017 Oct 21.

PMID:
29102816
15.

Stinging caterpillars from the genera Podalia, Leucanella and Lonomia in Misiones, Argentina: A preliminary comparative approach to understand their toxicity.

Quintana MA, Sciani JM, Auada AVV, Martínez MM, Sánchez MN, Santoro ML, Fan HW, Peichoto ME.

Comp Biochem Physiol C Toxicol Pharmacol. 2017 Nov;202:55-62. doi: 10.1016/j.cbpc.2017.07.007. Epub 2017 Aug 2.

PMID:
28778491
16.

The gingival vein as a minimally traumatic site for multiple blood sampling in guinea pigs and hamsters.

Rodrigues MV, de Castro SO, de Albuquerque CZ, Mattaraia VGM, Santoro ML.

PLoS One. 2017 May 22;12(5):e0177967. doi: 10.1371/journal.pone.0177967. eCollection 2017.

17.

Gene expression in blood of children and adolescents: Mediation between childhood maltreatment and major depressive disorder.

Spindola LM, Pan PM, Moretti PN, Ota VK, Santoro ML, Cogo-Moreira H, Gadelha A, Salum G, Manfro GG, Mari JJ, Brentani H, Grassi-Oliveira R, Brietzke E, Miguel EC, Rohde LA, Sato JR, Bressan RA, Belangero SI.

J Psychiatr Res. 2017 Sep;92:24-30. doi: 10.1016/j.jpsychires.2017.03.015. Epub 2017 Mar 22.

PMID:
28384542
18.

Shorter leukocyte telomere length in patients at ultra high risk for psychosis.

Maurya PK, Rizzo LB, Xavier G, Tempaku PF, Zeni-Graiff M, Santoro ML, Mazzotti DR, Zugman A, Pan P, Noto C, Maes M, Asevedo E, Mansur RB, Cunha GR, Gadelha A, Bressan RA, Belangero SI, Brietzke E.

Eur Neuropsychopharmacol. 2017 May;27(5):538-542. doi: 10.1016/j.euroneuro.2017.02.008. Epub 2017 Mar 6.

PMID:
28274506
19.

Gene expression alterations related to mania and psychosis in peripheral blood of patients with a first episode of psychosis.

Gouvea ES, Ota VK, Noto C, Santoro ML, Spindola LM, Moretti PN, Carvalho CM, Xavier G, Rios AC, Sato JR, Hayashi MA, Brietzke E, Gadelha A, Bressan RA, Cordeiro Q, Belangero SI.

Transl Psychiatry. 2016 Oct 4;6(10):e908. doi: 10.1038/tp.2016.159.

20.

A current snapshot of common genomic variants contribution in psychiatric disorders.

Santoro ML, Moretti PN, Pellegrino R, Gadelha A, Abílio VC, Hayashi MA, Belangero SI, Hakonarson H.

Am J Med Genet B Neuropsychiatr Genet. 2016 Dec;171(8):997-1005. doi: 10.1002/ajmg.b.32475. Epub 2016 Aug 3. Review.

PMID:
27486013
21.

Biochemical and biological characterization of Bothriechis schlegelii snake venoms from Colombia and Costa Rica.

Prezotto-Neto JP, Kimura LF, Alves AF, Gutiérrez JM, Otero R, Suárez AM, Santoro ML, Barbaro KC.

Exp Biol Med (Maywood). 2016 Dec;241(18):2075-2085. doi: 10.1177/1535370216660214. Epub 2016 Jul 24.

22.

Patagonfibrase modifies protein expression of tissue factor and protein disulfide isomerase in rat skin.

Peichoto ME, Santoro ML.

Toxicon. 2016 Sep 1;119:330-5. doi: 10.1016/j.toxicon.2016.07.001. Epub 2016 Jul 4.

PMID:
27390042
23.

Ontogenetic Variation in Biological Activities of Venoms from Hybrids between Bothrops erythromelas and Bothrops neuwiedi Snakes.

Santoro ML, do Carmo T, Cunha BH, Alves AF, Zelanis A, Serrano SM, Grego KF, Sant'Anna SS, Barbaro KC, Fernandes W.

PLoS One. 2015 Dec 29;10(12):e0145516. doi: 10.1371/journal.pone.0145516. eCollection 2015.

24.

Summaries of plenary, symposia, and oral sessions at the XXII World Congress of Psychiatric Genetics, Copenhagen, Denmark, 12-16 October 2014.

Aas M, Blokland GA, Chawner SJ, Choi SW, Estrada J, Forsingdal A, Friedrich M, Ganesham S, Hall L, Haslinger D, Huckins L, Loken E, Malan-Müller S, Martin J, Misiewicz Z, Pagliaroli L, Pardiñas AF, Pisanu C, Quadri G, Santoro ML, Shaw AD, Ranlund S, Song J, Tesli M, Tropeano M, van der Voet M, Wolfe K, Cormack FK, DeLisi L.

Psychiatr Genet. 2016 Feb;26(1):1-47. doi: 10.1097/YPG.0000000000000112.

PMID:
26565519
25.

Depression, Cytokine, and Cytokine by Treatment Interactions Modulate Gene Expression in Antipsychotic Naïve First Episode Psychosis.

Noto C, Ota VK, Santoro ML, Gouvea ES, Silva PN, Spindola LM, Cordeiro Q, Bressan RA, Gadelha A, Brietzke E, Belangero SI, Maes M.

Mol Neurobiol. 2016 Oct;53(8):5701-9. doi: 10.1007/s12035-015-9489-3. Epub 2015 Oct 22.

PMID:
26491028
26.

Increased expression of NDEL1 and MBP genes in the peripheral blood of antipsychotic-naïve patients with first-episode psychosis.

Ota VK, Noto C, Santoro ML, Spindola LM, Gouvea ES, Carvalho CM, Santos CM, Xavier G, Higuchi CH, Yonamine C, Moretti PN, Abílio VC, Hayashi MA, Brietzke E, Gadelha A, Cordeiro Q, Bressan RA, Belangero SI.

Eur Neuropsychopharmacol. 2015 Dec;25(12):2416-25. doi: 10.1016/j.euroneuro.2015.09.013. Epub 2015 Oct 9.

PMID:
26476704
27.

Serum brain-derived neurotrophic factor and cortical thickness are differently related in patients with schizophrenia and controls.

Zugman A, Pedrini M, Gadelha A, Kempton MJ, Noto CS, Mansur RB, Santoro ML, Gama CS, Bressan RA, McGuire P, Jackowski AP, Brietzke E.

Psychiatry Res. 2015 Oct 30;234(1):84-9. doi: 10.1016/j.pscychresns.2015.08.009. Epub 2015 Aug 28.

PMID:
26341949
28.

Low expression of Gria1 and Grin1 glutamate receptors in the nucleus accumbens of Spontaneously Hypertensive Rats (SHR).

Diana MC, Santoro ML, Xavier G, Santos CM, Spindola LN, Moretti PN, Ota VK, Bressan RA, Abilio VC, Belangero SI.

Psychiatry Res. 2015 Oct 30;229(3):690-4. doi: 10.1016/j.psychres.2015.08.021. Epub 2015 Aug 12.

PMID:
26296755
29.

Isolation and Characterization of IgM and IgY Antibodies from Plasma of Magellanic Penguins (Spheniscus magellanicus).

Bizelli CC, Silva AS, da Costa JD, Vanstreels RE, Atzingen MV, Santoro ML, Fernandes I, Catão-Dias JL, Faquim-Mauro EL.

Avian Dis. 2015 Mar;59(1):79-86.

PMID:
26292539
30.

Platelet participation in the pathogenesis of dermonecrosis induced by Loxosceles gaucho venom.

Tavares FL, Peichoto ME, Marcelino JR, Barbaro KC, Cirillo MC, Santoro ML, Sano-Martins IS.

Hum Exp Toxicol. 2016 Jun;35(6):666-76. doi: 10.1177/0960327115597983. Epub 2015 Aug 6.

PMID:
26253591
31.

Mast cells and histamine play an important role in edema and leukocyte recruitment induced by Potamotrygon motoro stingray venom in mice.

Kimura LF, Prezotto-Neto JP, Távora BC, Faquim-Mauro EL, Pereira NA, Antoniazzi MM, Jared SG, Teixeira CF, Santoro ML, Barbaro KC.

Toxicon. 2015 Sep;103:65-73. doi: 10.1016/j.toxicon.2015.06.006. Epub 2015 Jun 19.

PMID:
26100666
32.

Gene expression analysis in blood of ultra-high risk subjects compared to first-episode of psychosis patients and controls.

Santoro ML, Gadelha A, Ota VK, Cunha GR, Asevedo E, Noto CS, Spindola LM, Pan PM, Talarico F, Mansur RB, Silva PN, Brietzke E, Cordeiro Q, Bressan RA, Belangero SI.

World J Biol Psychiatry. 2015 Sep;16(6):441-446. doi: 10.3109/15622975.2015.1048724. Epub 2015 Jun 18.

PMID:
26089098
33.

Bothrops jararaca envenomation: Pathogenesis of hemostatic disturbances and intravascular hemolysis.

Senise LV, Yamashita KM, Santoro ML.

Exp Biol Med (Maywood). 2015 Nov;240(11):1528-36. doi: 10.1177/1535370215590818. Epub 2015 Jun 16.

34.

Effects of depression on the cytokine profile in drug naïve first-episode psychosis.

Noto C, Ota VK, Santoro ML, Ortiz BB, Rizzo LB, Higuchi CH, Cordeiro Q, Belangero SI, Bressan RA, Gadelha A, Maes M, Brietzke E.

Schizophr Res. 2015 May;164(1-3):53-8. doi: 10.1016/j.schres.2015.01.026. Epub 2015 Feb 21.

PMID:
25716958
35.

Changes in gene expression and methylation in the blood of patients with first-episode psychosis.

Ota VK, Noto C, Gadelha A, Santoro ML, Spindola LM, Gouvea ES, Stilhano RS, Ortiz BB, Silva PN, Sato JR, Han SW, Cordeiro Q, Bressan RA, Belangero SI.

Schizophr Res. 2014 Nov;159(2-3):358-64. doi: 10.1016/j.schres.2014.09.008. Epub 2014 Sep 28.

PMID:
25270546
36.

Expression profile of neurotransmitter receptor and regulatory genes in the prefrontal cortex of spontaneously hypertensive rats: relevance to neuropsychiatric disorders.

Santoro ML, Santos CM, Ota VK, Gadelha A, Stilhano RS, Diana MC, Silva PN, Spíndola LM, Melaragno MI, Bressan RA, Han SW, Abílio VC, Belangero SI.

Psychiatry Res. 2014 Nov 30;219(3):674-9. doi: 10.1016/j.psychres.2014.05.034. Epub 2014 Jun 5.

PMID:
25041985
37.

Evaluation of neurotransmitter receptor gene expression identifies GABA receptor changes: a follow-up study in antipsychotic-naïve patients with first-episode psychosis.

Ota VK, Noto C, Gadelha A, Santoro ML, Ortiz BB, Andrade EH, Tasso BC, Spindola LM, Silva PN, Abílio VC, Smith Mde A, Sato JR, Brietzke E, Cordeiro Q, Bressan RA, Belangero SI.

J Psychiatr Res. 2014 Sep;56:130-6. doi: 10.1016/j.jpsychires.2014.05.012. Epub 2014 Jun 4.

PMID:
24935901
38.

Effect of antipsychotic drugs on gene expression in the prefrontal cortex and nucleus accumbens in the spontaneously hypertensive rat (SHR).

Santoro ML, Ota VK, Stilhano RS, Silva PN, Santos CM, Diana MC, Gadelha A, Bressan RA, Melaragno MI, Han SW, Abílio VC, Belangero SI.

Schizophr Res. 2014 Aug;157(1-3):163-8. doi: 10.1016/j.schres.2014.05.015. Epub 2014 Jun 2.

PMID:
24893910
39.

Bothrops jararaca venom metalloproteinases are essential for coagulopathy and increase plasma tissue factor levels during envenomation.

Yamashita KM, Alves AF, Barbaro KC, Santoro ML.

PLoS Negl Trop Dis. 2014 May 15;8(5):e2814. doi: 10.1371/journal.pntd.0002814. eCollection 2014 May.

40.

Characterization of inflammatory response induced by Potamotrygon motoro stingray venom in mice.

Kimura LF, Prezotto-Neto JP, Antoniazzi MM, Jared SG, Santoro ML, Barbaro KC.

Exp Biol Med (Maywood). 2014 May;239(5):601-9. doi: 10.1177/1535370214523704. Epub 2014 Mar 25.

PMID:
24668554
41.

PRODH polymorphisms, cortical volumes and thickness in schizophrenia.

Ota VK, Bellucco FT, Gadelha A, Santoro ML, Noto C, Christofolini DM, Assunção IB, Yamada KM, Ribeiro-dos-Santos AK, Santos S, Mari JJ, Smith MA, Melaragno MI, Bressan RA, Sato JR, Jackowski AP, Belangero SI.

PLoS One. 2014 Feb 3;9(2):e87686. doi: 10.1371/journal.pone.0087686. eCollection 2014.

42.

Local inflammatory reaction induced by Scolopendra viridicornis centipede venom in mice.

Kimura LF, Prezotto-Neto JP, Távora Bde C, Antoniazzi MM, Knysak I, Gióia Guizze SP, Santoro ML, Barbaro KC.

Toxicon. 2013 Dec 15;76:239-46. doi: 10.1016/j.toxicon.2013.10.017. Epub 2013 Oct 17.

PMID:
24140924
43.

Neurotransmitter receptor and regulatory gene expression in peripheral blood of Brazilian drug-naïve first-episode psychosis patients before and after antipsychotic treatment.

Ota VK, Noto C, Gadelha A, Santoro ML, Silva PN, Melaragno MI, Smith Mde A, Cordeiro Q, Bressan RA, Belangero SI.

Psychiatry Res. 2013 Dec 30;210(3):1290-2. doi: 10.1016/j.psychres.2013.09.016. Epub 2013 Oct 7.

PMID:
24113126
44.

Cloning, expression and characterization of a phospholipase D from Loxosceles gaucho venom gland.

Magalhães GS, Caporrino MC, Della-Casa MS, Kimura LF, Prezotto-Neto JP, Fukuda DA, Portes-Junior JA, Neves-Ferreira AG, Santoro ML, Barbaro KC.

Biochimie. 2013 Sep;95(9):1773-83. doi: 10.1016/j.biochi.2013.06.002. Epub 2013 Jun 14.

PMID:
23770445
45.

Polymorphisms in schizophrenia candidate gene UFD1L may contribute to cognitive deficits.

Ota VK, Berberian AA, Gadelha A, Santoro ML, Ottoni GL, Matsuzaka CT, Mari JJ, Melaragno MI, Lara DR, Smith MA, Belangero SI, Bressan RA.

Psychiatry Res. 2013 Aug 30;209(1):110-3. doi: 10.1016/j.psychres.2013.03.035. Epub 2013 Apr 23.

PMID:
23623450
46.

Candidate genes for schizophrenia in a mixed Brazilian population using pooled DNA.

Ota VK, Gadelha A, Pellegrino R, Santoro ML, Bellucco FT, Christofolini DM, Ottoni GL, Lara DR, Ribeiro-Dos-Santos AK, Santos S, Mari JJ, Breen G, Smith MA, Bressan RA, Melaragno MI, Belangero SI.

Psychiatry Res. 2013 Jul 30;208(2):201-2. doi: 10.1016/j.psychres.2012.12.009. Epub 2013 Feb 16. No abstract available.

PMID:
23419840
47.

ZDHHC8 gene may play a role in cortical volumes of patients with schizophrenia.

Ota VK, Gadelha A, Assunção IB, Santoro ML, Christofolini DM, Bellucco FT, Santos-Filho AF, Ottoni GL, Lara DR, Mari JJ, Melaragno MI, Smith MA, Bressan RA, Belangero SI, Jackowski AP.

Schizophr Res. 2013 Apr;145(1-3):33-5. doi: 10.1016/j.schres.2013.01.011. Epub 2013 Feb 8.

PMID:
23403413
48.

DRD1 rs4532 polymorphism: a potential pharmacogenomic marker for treatment response to antipsychotic drugs.

Ota VK, Spíndola LN, Gadelha A, dos Santos Filho AF, Santoro ML, Christofolini DM, Bellucco FT, Ribeiro-dos-Santos ÂK, Santos S, Mari Jde J, Melaragno MI, Bressan RA, Smith Mde A, Belangero SI.

Schizophr Res. 2012 Dec;142(1-3):206-8. doi: 10.1016/j.schres.2012.08.003. Epub 2012 Oct 1.

PMID:
23036699
49.

Venom proteomes of South and North American opisthoglyphous (Colubridae and Dipsadidae) snake species: a preliminary approach to understanding their biological roles.

Peichoto ME, Tavares FL, Santoro ML, Mackessy SP.

Comp Biochem Physiol Part D Genomics Proteomics. 2012 Dec;7(4):361-9. doi: 10.1016/j.cbd.2012.08.001. Epub 2012 Aug 21.

PMID:
22974712
50.

Clinical picture and laboratorial evaluation in human loxoscelism.

Malaque CM, Santoro ML, Cardoso JL, Conde MR, Novaes CT, Risk JY, França FO, de Medeiros CR, Fan HW.

Toxicon. 2011 Dec 1;58(8):664-71. doi: 10.1016/j.toxicon.2011.09.011. Epub 2011 Oct 2.

PMID:
21986355

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