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Items: 1 to 50 of 1271

1.

The Zinc-finger AN1-type Domain 2a Gene Acts as a Regulator of Cell Survival in Human Melanoma: Role of E3-Ligase cIAP2.

Scomazzon SP, Riccio A, Santopolo S, Lanzilli G, Coccia M, Rossi A, Santoro MG.

Mol Cancer Res. 2019 Sep 20. pii: molcanres.0243.2019. doi: 10.1158/1541-7786.MCR-19-0243. [Epub ahead of print]

PMID:
31540997
2.

Dual-Chambered Membrane Bioreactor for Co-Culture of Stratified Cell Populations.

Navarro J, Swayambunathan J, Janes ME, Santoro M, Mikos AG, Fisher JP.

Biotechnol Bioeng. 2019 Sep 10. doi: 10.1002/bit.27164. [Epub ahead of print]

PMID:
31502660
3.

The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis.

Milton ME, Draughn GL, Bobay BG, Stowe SD, Olson AL, Feldmann EA, Thompson RJ, Myers KH, Santoro MT, Kearns DB, Cavanagh J.

J Mol Biol. 2019 Sep 4. pii: S0022-2836(19)30543-1. doi: 10.1016/j.jmb.2019.08.019. [Epub ahead of print]

PMID:
31493408
4.

Lower prevalence of Blastocystis sp. infections in HIV positive compared to HIV negative adults in Ghana.

Di Cristanziano V, D'Alfonso R, Berrilli F, Sarfo FS, Santoro M, Fabeni L, Knops E, Heger E, Kaiser R, Dompreh A, Phillips RO, Norman B, Feldt T, Eberhardt KA.

PLoS One. 2019 Sep 3;14(9):e0221968. doi: 10.1371/journal.pone.0221968. eCollection 2019.

5.

Comparison between thrombotic risk scores in essential thrombocythemia and survival implications.

Santoro M, Accurso V, Mancuso S, Carlisi M, Raso S, Tarantino G, Di Piazza F, Perez A, Russo A, Siragusa S.

Hematol Oncol. 2019 Aug 29. doi: 10.1002/hon.2670. [Epub ahead of print]

PMID:
31465530
6.

Massive Taenia hydatigena Cysticercosis in a Wild Boar (Sus scrofa) from Italy.

Sgroi G, Varcasia A, Dessì G, D'Alessio N, Pacifico L, Buono F, Neola B, Fusco G, Santoro M, Toscano V, Fioretti A, Veneziano V.

Acta Parasitol. 2019 Aug 23. doi: 10.2478/s11686-019-00110-3. [Epub ahead of print]

PMID:
31444647
7.

The TRAPP complex mediates secretion arrest induced by stress granule assembly.

Zappa F, Wilson C, Di Tullio G, Santoro M, Pucci P, Monti M, D'Amico D, Pisonero-Vaquero S, De Cegli R, Romano A, Saleem MA, Polishchuk E, Failli M, Giaquinto L, De Matteis MA.

EMBO J. 2019 Aug 20:e101704. doi: 10.15252/embj.2019101704. [Epub ahead of print]

PMID:
31429971
8.

Genetic risk for Alzheimer's disease and functional brain connectivity in children and adolescents.

Axelrud LK, Sato JR, Santoro ML, Talarico F, Pine DS, Rohde LA, Zugman A, Junior EA, Bressan RA, Grassi-Oliveira R, Pan PM, Hoffmann MS, Simioni AR, Guinjoan SM, Hakonarson H, Brietzke E, Gadelha A, Pellegrino da Silva R, Hoexter MQ, Miguel EC, Belangero SI, Salum GA.

Neurobiol Aging. 2019 Jul 6;82:10-17. doi: 10.1016/j.neurobiolaging.2019.06.011. [Epub ahead of print]

PMID:
31376729
9.

Cystic echinococcosis in wild boars (Sus scrofa) from southern Italy: Epidemiological survey and molecular characterization.

Sgroi G, Varcasia A, Dessi G, D'Alessio N, Tamponi C, Saarma U, Laurimäe T, Kinkar L, Santoro M, Caputo V, Sarnelli P, Fusco G, Varuzza P, Fioretti A, Scala A, Veneziano V.

Int J Parasitol Parasites Wildl. 2019 Jun 9;9:305-311. doi: 10.1016/j.ijppaw.2019.04.013. eCollection 2019 Aug.

10.

Evaluation of HIV-1 integrase resistance emergence and evolution in patients treated with integrase inhibitors.

Scutari R, Alteri C, Vicenti I, Carlo DD, Zuccaro V, Incardona F, Borghi V, Bezenchek A, Andreoni M, Antinori A, Perno CF, Cascio A, Luca A, Zazzi M, Santoro MM; ARCA (Antiviral Response Cohort Analysis) study Group.

J Glob Antimicrob Resist. 2019 Jul 19. pii: S2213-7165(19)30181-X. doi: 10.1016/j.jgar.2019.07.015. [Epub ahead of print]

PMID:
31330378
11.

Epidemiology of Dandy-Walker Malformation in Europe: A EUROCAT Population-Based Registry Study.

Santoro M, Coi A, Barišić I, Garne E, Addor MC, Bergman JEH, Bianchi F, Boban L, Braz P, Cavero-Carbonell C, Gatt M, Haeusler M, Kinsner-Ovaskainen A, Klungsøyr K, Kurinczuk JJ, Lelong N, Luyt K, Materna-Kiryluk A, Mokoroa O, Mullaney C, Nelen V, Neville AJ, O'Mahony MT, Perthus I, Randrianaivo H, Rankin J, Rissmann A, Rouget F, Schaub B, Tucker D, Wellesley D, Yevtushok L, Pierini A.

Neuroepidemiology. 2019 Jul 12:1-11. doi: 10.1159/000501238. [Epub ahead of print]

PMID:
31302658
12.

[SENTIERI: Epidemiological Study of Residents in National Priority Contaminated Sites. Fifth Report].

Zona A, Iavarone I, Buzzoni C, Conti S, Santoro M, Fazzo L, Pasetto R, Pirastu R, Bruno C, Ancona C, Bianchi F, Forastiere F, Manno V, Minelli G, Minerba A, Minichilli F, Stoppa G, Pierini A, Ricci P, Scondotto S, Bisceglia L, Cernigliaro A, Ranzi A, Comba P; Gruppo di lavoro SENTIERI; Gruppo di lavoro AIRTUM-SENTIERI; Gruppo di lavoro Malformazioni congenite-SENTIERI.

Epidemiol Prev. 2019 Mar-Jun;43(2-3 Suppl 1):1-208. doi: 10.19191/EP19.2-3.S1.032. Italian.

13.

Epidemiology of achondroplasia: A population-based study in Europe.

Coi A, Santoro M, Garne E, Pierini A, Addor MC, Alessandri JL, Bergman JEH, Bianchi F, Boban L, Braz P, Cavero-Carbonell C, Gatt M, Haeusler M, Klungsøyr K, Kurinczuk JJ, Lanzoni M, Lelong N, Luyt K, Mokoroa O, Mullaney C, Nelen V, Neville AJ, O'Mahony MT, Perthus I, Rankin J, Rissmann A, Rouget F, Schaub B, Tucker D, Wellesley D, Wisniewska K, Zymak-Zakutnia N, Barišić I.

Am J Med Genet A. 2019 Sep;179(9):1791-1798. doi: 10.1002/ajmg.a.61289. Epub 2019 Jul 11.

PMID:
31294928
14.

Real-time PCR detection of Toxoplasma gondii in tissue samples of wild boars (Sus scrofa) from southern Italy reveals high prevalence and parasite load.

Santoro M, Viscardi M, Sgroi G, DʼAlessio N, Veneziano V, Pellicano R, Brunetti R, Fusco G.

Parasit Vectors. 2019 Jul 5;12(1):335. doi: 10.1186/s13071-019-3586-5.

15.

Evaluation of treatment response, drug resistance and HIV-1 variability among adolescents on first- and second-line antiretroviral therapy: a study protocol for a prospective observational study in the centre region of Cameroon (EDCTP READY-study).

Fokam J, Santoro MM, Takou D, Njom-Nlend AE, Ndombo PK, Kamgaing N, Kamta C, Essiane A, Sosso SM, Ndjolo A, Colizzi V, Perno CF.

BMC Pediatr. 2019 Jul 5;19(1):226. doi: 10.1186/s12887-019-1599-z.

16.

Quantification of HIV-DNA and residual viremia in patients starting ART by droplet digital PCR: Their dynamic decay and correlations with immunological parameters and virological success.

Alteri C, Scutari R, Stingone C, Maffongelli G, Brugneti M, Falasca F, Martini S, Bertoli A, Turriziani O, Sarmati L, Coppola N, Andreoni M, Santoro MM, Perno CF, Ceccherini-Silberstein F, Svicher V.

J Clin Virol. 2019 Aug;117:61-67. doi: 10.1016/j.jcv.2019.06.004. Epub 2019 Jun 14.

PMID:
31229934
17.

Advantages and Challenges of Cardiovascular and Lymphatic Studies in Zebrafish Research.

Santoro MM, Beltrame M, Panáková D, Siekmann AF, Tiso N, Venero Galanternik M, Jung HM, Weinstein BM.

Front Cell Dev Biol. 2019 May 28;7:89. doi: 10.3389/fcell.2019.00089. eCollection 2019.

18.

Molecular detection of Chlamydia abortus in a stranded Mediterranean striped dolphin Stenella coeruleoalba.

Santoro M, Iaccarino D, Di Nocera F, Degli Uberti B, Lucibelli MG, Borriello G, De Luca G, D'Amore M, Cerrone A, Galiero G.

Dis Aquat Organ. 2019 Jan 24;132(3):203-208. doi: 10.3354/dao03320.

PMID:
31188135
19.

Induction of essential oil production in Mentha x piperita by plant growth promoting bacteria was correlated with an increase in jasmonate and salicylate levels and a higher density of glandular trichomes.

Cappellari LDR, Santoro MV, Schmidt A, Gershenzon J, Banchio E.

Plant Physiol Biochem. 2019 Aug;141:142-153. doi: 10.1016/j.plaphy.2019.05.030. Epub 2019 May 29.

PMID:
31163341
20.

Beyond the comfort zone of deep molecular response: discontinuation in major molecular response chronic myeloid leukemia.

Dragani M, Rege-Cambrin G, Ferrero D, Abruzzese E, Pregno P, Elena C, Cedrone M, Santoro M, Andreani G, Saglio G, Fava C.

Leuk Lymphoma. 2019 Jun 4:1-3. doi: 10.1080/10428194.2019.1622103. [Epub ahead of print] No abstract available.

PMID:
31161827
21.

Age at diagnosis is an important prognostic factor in Philadelphia-negative Myeloproliferative Neoplasms.

Accurso V, Santoro M, Siragusa S.

Eur J Haematol. 2019 Aug;103(2):140-141. doi: 10.1111/ejh.13266. Epub 2019 Jun 13. No abstract available.

PMID:
31121064
22.

Characterisation of HIV-1 molecular transmission clusters among newly diagnosed individuals infected with non-B subtypes in Italy.

Fabeni L, Alteri C, Berno G, Scutari R, Orchi N, De Carli G, Bertoli A, Carioti L, Gori C, Forbici F, Salpini R, Vergori A, Gagliardini R, Cicalini S, Mondi A, Pinnetti C, Mazzuti L, Turriziani O, Colafigli M, Borghi V, Montella F, Pennica A, Lichtner M, Girardi E, Andreoni M, Mussini C, Antinori A, Ceccherini-Silberstein F, Perno CF, Santoro MM; SENDIH Study group.

Sex Transm Infect. 2019 May 10. pii: sextrans-2019-054017. doi: 10.1136/sextrans-2019-054017. [Epub ahead of print]

PMID:
31076456
23.

Is the rate of virological failure to cART continuing to decline in recent calendar years?

Rusconi S, Santoro MM, Gianotti N, Antinori A, Bonora S, Cingolani A, Ceccherini Silberstein F, Tavelli A, d'Arminio Monforte A, Cozzi-Lepri A; Icona Foundation Study Group.

J Clin Virol. 2019 Jul;116:23-28. doi: 10.1016/j.jcv.2019.04.009. Epub 2019 May 3.

24.

A cross-talk between blood-cell neuroplasticity-related genes and environmental enrichment in working dogs.

Guelfi G, Casano AB, Menchetti L, Bellicci M, Suvieri C, Moscati L, Carotenuto P, Santoro MM, Diverio S.

Sci Rep. 2019 May 6;9(1):6910. doi: 10.1038/s41598-019-43402-4.

25.

Laser-Synthesized SERS Substrates as Sensors toward Therapeutic Drug Monitoring.

Tommasini M, Zanchi C, Lucotti A, Bombelli A, Villa NS, Casazza M, Ciusani E, de Grazia U, Santoro M, Fazio E, Neri F, Trusso S, Ossi PM.

Nanomaterials (Basel). 2019 May 1;9(5). pii: E677. doi: 10.3390/nano9050677.

26.

Immersion anaesthesia with ethanol in African giant land snails (Acathina fulica).

d'Ovidio D, Monticelli P, Santoro M, Adami C.

Heliyon. 2019 Apr 25;5(4):e01546. doi: 10.1016/j.heliyon.2019.e01546. eCollection 2019 Apr.

27.

Molecular detection and characterization of carnivore parvoviruses in free-ranging Eurasian otters (Lutra lutra) in southern Italy.

Viscardi M, Santoro M, Clausi MT, Cozzolino L, Decaro N, Colaianni ML, Fusco G.

Transbound Emerg Dis. 2019 Sep;66(5):1864-1872. doi: 10.1111/tbed.13212. Epub 2019 May 12.

PMID:
31022323
28.

Retraction: FRA-1 Expression in Hyperplastic and Neoplastic Thyroid Diseases.

Chiappetta G, Tallini G, De Biasio MC, Pentimalli F, de Nigris F, Losito S, Fedele M, Battista S, Verde P, Santoro M, Fusco A.

Clin Cancer Res. 2019 Apr 15;25(8):2675. doi: 10.1158/1078-0432.CCR-19-0487. No abstract available.

PMID:
30988099
29.

Very high pre-therapy viral load is a predictor of virological rebound in HIV-1-infected patients starting a modern first-line regimen.

Armenia D, Di Carlo D, Cozzi-Lepri A, Calcagno A, Borghi V, Gori C, Bertoli A, Gennari W, Bellagamba R, Castagna A, Latini A, Pinnetti C, Cicalini S, Saracino A, Lapadula G, Rusconi S, Castelli F, Di Giambenedetto S, Andreoni M, Di Perri G, Antinori A, Mussini C, Ceccherini-Silberstein F, Monforte AD, Perno CF, Santoro MM; ICONA Foundation Study Group.

Antivir Ther. 2019 Apr 12. doi: 10.3851/IMP3309. [Epub ahead of print]

PMID:
30977466
30.

Occurrence of Rhabditid Nematodes in the Pet Giant African Land Snails (Achatina fulica).

d'Ovidio D, Nermut J, Adami C, Santoro M.

Front Vet Sci. 2019 Mar 26;6:88. doi: 10.3389/fvets.2019.00088. eCollection 2019.

31.

Correction to: Epidemiology of Sulcascaris sulcata (Nematoda: Anisakidae) ulcerous gastritis in the Mediterranean loggerhead sea turtle (Caretta caretta).

Santoro M, Marchiori E, Iaccarino D, Uberti BD, Cassini R, Di Nocera F, Cerrone A, Galiero G, Marcer F.

Parasitol Res. 2019 May;118(5):1687. doi: 10.1007/s00436-019-06304-y.

PMID:
30945016
32.

Gene expression over the course of schizophrenia: from clinical high-risk for psychosis to chronic stages.

Ota VK, Moretti PN, Santoro ML, Talarico F, Spindola LM, Xavier G, Carvalho CM, Marques DF, Costa GO, Pellegrino R, de Jong S, Cordeiro Q, Hakonarson H, Breen G, Noto C, Bressan RA, Gadelha A, Jesus Mari J, Belangero SI.

NPJ Schizophr. 2019 Mar 28;5(1):5. doi: 10.1038/s41537-019-0073-0.

33.

DGCR2 influences cortical thickness through a mechanism independent of schizophrenia pathogenesis.

Belangero SI, Ota VK, Gadelha A, Berberian AA, Assunção-Leme IB, Noto C, Christofolini DM, Bellucco FT, Santoro ML, Mazzotti DR, Zugman A, Melaragno MI, Smith MAC, Pellegrino R, Hakonarson H, Cordeiro Q, Moretti PN, Bressan RA, Mari JJ, Jackowski AP.

Psychiatry Res. 2019 Apr;274:391-394. doi: 10.1016/j.psychres.2019.02.068. Epub 2019 Feb 27.

PMID:
30901624
34.

Nano-Sampling and Reporter Tools to Study Metabolic Regulation in Zebrafish.

Dickmeis T, Feng Y, Mione MC, Ninov N, Santoro M, Spaink HP, Gut P.

Front Cell Dev Biol. 2019 Feb 19;7:15. doi: 10.3389/fcell.2019.00015. eCollection 2019.

35.

HIV-1 drug resistance testing is essential for heavily-treated patients switching from first- to second-line regimens in resource-limited settings: evidence from routine clinical practice in Cameroon.

Takou D, Fokam J, Teto G, Santoro MM, Ceccherini-Silberstein F, Nanfack AJ, Sosso SM, Dambaya B, Salpini R, Billong SC, Gori C, Fokunang CN, Cappelli G, Colizzi V, Perno CF, Ndjolo A.

BMC Infect Dis. 2019 Mar 12;19(1):246. doi: 10.1186/s12879-019-3871-0.

36.

Protein disulfide isomerase plasma levels in healthy humans reveal proteomic signatures involved in contrasting endothelial phenotypes.

Oliveira PVS, Garcia-Rosa S, Sachetto ATA, Moretti AIS, Debbas V, De Bessa TC, Silva NT, Pereira ADC, Martins-de-Souza D, Santoro ML, Laurindo FRM.

Redox Biol. 2019 Apr;22:101142. doi: 10.1016/j.redox.2019.101142. Epub 2019 Feb 19.

37.

Epidemiology of Sulcascaris sulcata (Nematoda: Anisakidae) ulcerous gastritis in the Mediterranean loggerhead sea turtle (Caretta caretta).

Santoro M, Marchiori E, Iaccarino D, Uberti BD, Cassini R, Di Nocera F, Cerrone A, Galiero G, Marcer F.

Parasitol Res. 2019 May;118(5):1457-1463. doi: 10.1007/s00436-019-06283-0. Epub 2019 Mar 11. Erratum in: Parasitol Res. 2019 Apr 3;:.

PMID:
30859311
38.

Efficacy of ruxolitinib retreatment in a patient with high-risk myelofibrosis using the international prognostic scoring system.

Accurso V, Santoro M, Mancuso S, Napolitano M, Di Piazza F, Russo A, Siragusa SM.

Drugs Context. 2019 Mar 4;8:212569. doi: 10.7573/dic.212569. eCollection 2019. No abstract available.

39.

Observational study of chronic myeloid leukemia Italian patients who discontinued tyrosine kinase inhibitors in clinical practice.

Fava C, Rege-Cambrin G, Dogliotti I, Cerrano M, Berchialla P, Dragani M, Rosti G, Castagnetti F, Gugliotta G, Martino B, Gambacorti-Passerini C, Abruzzese E, Elena C, Pregno P, Gozzini A, Capodanno I, Bergamaschi M, Crugnola M, Bocchia M, Galimberti S, Rapezzi D, Iurlo A, Cattaneo D, Latagliata R, Breccia M, Cedrone M, Santoro M, Annunziata M, Levato L, Stagno F, Cavazzini F, Sgherza N, Giai V, Luciano L, Russo S, Musto P, Caocci G, Sorà F, Iuliano F, Lunghi F, Specchia G, Pane F, Ferrero D, Baccarani M, Saglio G.

Haematologica. 2019 Aug;104(8):1589-1596. doi: 10.3324/haematol.2018.205054. Epub 2019 Feb 28.

40.

Integrase strand transfer inhibitor-based regimen is related with a limited HIV-1 V3 loop evolution in clinical practice.

Alteri C, Scutari R, Bertoli A, Armenia D, Gori C, Fabbri G, Mastroianni CM, Cerva C, Cristaudo A, Vicenti I, Bruzzone B, Zazzi M, Andreoni M, Antinori A, Svicher V, Ceccherini-Silberstein F, Perno CF, Santoro MM.

Virus Genes. 2019 Jun;55(3):290-297. doi: 10.1007/s11262-019-01649-z. Epub 2019 Feb 22.

PMID:
30796743
41.

Correction: BDNF rs6265 polymorphism methylation in Multiple Sclerosis: A possible marker of disease progression.

Nociti V, Santoro M, Quaranta D, Losavio FA, De Fino C, Giordano R, Palomba NP, Rossini PM, Guerini FR, Clerici M, Caputo D, Mirabella M.

PLoS One. 2019 Feb 21;14(2):e0212906. doi: 10.1371/journal.pone.0212906. eCollection 2019.

42.

Italian expert panel consensus statements on two-drug antiretroviral regimens to treat naïve and virologically suppressed HIV-1 infected patients.

Antinori A, Santoro MM, Gagliardini R, Marchetti G, Mondi A, Cento V, Perno CF, Andreoni M; Two-Drug Antiretroviral Regimens expert panel.

New Microbiol. 2019 Apr;42(2):69-80. Epub 2019 Feb 20. Review.

43.

Association between DNA methylation profile and malignancy in follicular-patterned thyroid neoplasms.

Affinito O, Salerno P, D'Alessio AM, Cuomo M, Florio E, Carlomagno F, Proietti A, Giannini R, Basolo F, Chiariotti L, Cocozza S, Santoro M.

Endocr Relat Cancer. 2019 Apr 1;26(4):451-462. doi: 10.1530/ERC-18-0308. Epub 2019 Feb 1.

PMID:
30753136
44.

Optimization of von Willebrand factor multimer analysis in vertical mini-gel electrophoresis systems: A rapid procedure.

Thomazini CM, Soares RPS, da Rocha TRF, Sachetto ATA, Santoro ML.

Thromb Res. 2019 Mar;175:76-83. doi: 10.1016/j.thromres.2019.01.018. Epub 2019 Jan 30.

PMID:
30731387
45.

Effects of the interaction between genetic factors and maltreatment on child and adolescent psychiatric disorders.

Carvalho CM, Pan PM, Ota VK, Spindola LM, Xavier G, Santoro ML, Mazzotti DR, Pellegrino R, Hakonarson H, Rohde LA, Miguel EC, Gadelha A, Bressan RA, Belangero SI.

Psychiatry Res. 2019 Mar;273:575-577. doi: 10.1016/j.psychres.2019.01.078. Epub 2019 Jan 29.

PMID:
30716596
46.

Comparative study of platelet aggregation and secretion induced by Bothrops jararaca snake venom and thrombin.

Rosa JG, de Albuquerque CZ, Mattaraia VGM, Santoro ML.

Toxicon. 2019 Mar 1;159:50-60. doi: 10.1016/j.toxicon.2019.01.003. Epub 2019 Jan 21.

PMID:
30677414
47.

Molecular determinants of ER-Golgi contacts identified through a new FRET-FLIM system.

Venditti R, Rega LR, Masone MC, Santoro M, Polishchuk E, Sarnataro D, Paladino S, D'Auria S, Varriale A, Olkkonen VM, Di Tullio G, Polishchuk R, De Matteis MA.

J Cell Biol. 2019 Mar 4;218(3):1055-1065. doi: 10.1083/jcb.201812020. Epub 2019 Jan 18.

48.

The activity of Sac1 across ER-TGN contact sites requires the four-phosphate-adaptor-protein-1.

Venditti R, Masone MC, Rega LR, Di Tullio G, Santoro M, Polishchuk E, Serrano IC, Olkkonen VM, Harada A, Medina DL, La Montagna R, De Matteis MA.

J Cell Biol. 2019 Mar 4;218(3):783-797. doi: 10.1083/jcb.201812021. Epub 2019 Jan 18.

49.

Downregulation of genes outside the deleted region in individuals with 22q11.2 deletion syndrome.

Dantas AG, Santoro ML, Nunes N, de Mello CB, Pimenta LSE, Meloni VA, Soares DCQ, Belangero SN, Carvalheira G, Kim CA, Melaragno MI.

Hum Genet. 2019 Jan;138(1):93-103. doi: 10.1007/s00439-018-01967-6. Epub 2019 Jan 9.

PMID:
30627818
50.

Before the Pump.

Norris DM, Santoro MM.

Arterioscler Thromb Vasc Biol. 2018 Dec;38(12):2763-2764. doi: 10.1161/ATVBAHA.118.311893. No abstract available.

PMID:
30571178

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