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Items: 1 to 50 of 403

1.

The yin-yang of the interaction between myelomonocytic cells and NK cells.

Molgora M, Supino D, Mavilio D, Santoni A, Moretta L, Mantovani A, Garlanda C.

Scand J Immunol. 2018 Jul 24:e12705. doi: 10.1111/sji.12705. [Epub ahead of print] Review.

PMID:
30048003
2.

Ca2+-activated K+ channels modulate microglia affecting motor neuron survival in hSOD1G93A mice.

Cocozza G, di Castro MA, Carbonari L, Grimaldi A, Antonangeli F, Garofalo S, Porzia A, Madonna M, Mainiero F, Santoni A, Grassi F, Wulff H, D'Alessandro G, Limatola C.

Brain Behav Immun. 2018 Jul 3. pii: S0889-1591(18)30288-5. doi: 10.1016/j.bbi.2018.07.002. [Epub ahead of print]

3.

"Immuno-Transient Receptor Potential Ion Channels": The Role in Monocyte- and Macrophage-Mediated Inflammatory Responses.

Santoni G, Morelli MB, Amantini C, Santoni M, Nabissi M, Marinelli O, Santoni A.

Front Immunol. 2018 Jun 6;9:1273. doi: 10.3389/fimmu.2018.01273. eCollection 2018. Review.

4.

hMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axis.

Di Modugno F, Spada S, Palermo B, Visca P, Iapicca P, Di Carlo A, Antoniani B, Sperduti I, Di Benedetto A, Terrenato I, Mottolese M, Gandolfi F, Facciolo F, Chen EI, Schwartz MA, Santoni A, Bissell MJ, Nisticò P.

Oncogene. 2018 Jun 15. doi: 10.1038/s41388-018-0364-3. [Epub ahead of print]

PMID:
29907768
5.

Re: Gut Microbiome Influences Efficacy of PD-1-based Immunotherapy Against Epithelial Tumors.

Santoni M, Piva F, Conti A, Santoni A, Cimadamore A, Scarpelli M, Battelli N, Montironi R.

Eur Urol. 2018 Jun 8. pii: S0302-2838(18)30422-6. doi: 10.1016/j.eururo.2018.05.033. [Epub ahead of print] No abstract available.

PMID:
29891391
6.

Tumor-Targeting Anti-CD20 Antibodies Mediate In Vitro Expansion of Memory Natural Killer Cells: Impact of CD16 Affinity Ligation Conditions and In Vivo Priming.

Capuano C, Battella S, Pighi C, Franchitti L, Turriziani O, Morrone S, Santoni A, Galandrini R, Palmieri G.

Front Immunol. 2018 May 11;9:1031. doi: 10.3389/fimmu.2018.01031. eCollection 2018.

7.

MICA-129 Dimorphism and Soluble MICA Are Associated With the Progression of Multiple Myeloma.

Zingoni A, Vulpis E, Cecere F, Amendola MG, Fuerst D, Saribekyan T, Achour A, Sandalova T, Nardone I, Peri A, Soriani A, Fionda C, Mariggiò E, Petrucci MT, Ricciardi MR, Mytilineos J, Cippitelli M, Cerboni C, Santoni A.

Front Immunol. 2018 May 1;9:926. doi: 10.3389/fimmu.2018.00926. eCollection 2018.

8.

Drug-Induced Senescent Multiple Myeloma Cells Elicit NK Cell Proliferation by Direct or Exosome-Mediated IL15 Trans-Presentation.

Borrelli C, Ricci B, Vulpis E, Fionda C, Ricciardi MR, Petrucci MT, Masuelli L, Peri A, Cippitelli M, Zingoni A, Santoni A, Soriani A.

Cancer Immunol Res. 2018 Jul;6(7):860-869. doi: 10.1158/2326-6066.CIR-17-0604. Epub 2018 Apr 24.

PMID:
29691234
9.

NKG2D and Its Ligands: "One for All, All for One".

Zingoni A, Molfetta R, Fionda C, Soriani A, Paolini R, Cippitelli M, Cerboni C, Santoni A.

Front Immunol. 2018 Mar 12;9:476. doi: 10.3389/fimmu.2018.00476. eCollection 2018. Review.

10.

Impact of bone marrow-derived signals on NK cell development and functional maturation.

Stabile H, Fionda C, Santoni A, Gismondi A.

Cytokine Growth Factor Rev. 2018 Mar 27. pii: S1359-6101(18)30038-8. doi: 10.1016/j.cytogfr.2018.03.008. [Epub ahead of print] Review.

PMID:
29622473
11.

NCR+ ILC3 maintain larger STAT4 reservoir via T-BET to regulate type 1 features upon IL-23 stimulation in mice.

Mikami Y, Scarno G, Zitti B, Shih HY, Kanno Y, Santoni A, O'Shea JJ, Sciumè G.

Eur J Immunol. 2018 Jul;48(7):1174-1180. doi: 10.1002/eji.201847480. Epub 2018 Apr 16.

PMID:
29524223
12.

Chemokine regulation of innate lymphoid cell tissue distribution and function.

Soriani A, Stabile H, Gismondi A, Santoni A, Bernardini G.

Cytokine Growth Factor Rev. 2018 Feb 14. pii: S1359-6101(18)30014-5. doi: 10.1016/j.cytogfr.2018.02.003. [Epub ahead of print] Review.

PMID:
29472011
13.

Hepatitis C virus direct-acting antivirals therapy impacts on extracellular vesicles microRNAs content and on their immunomodulating properties.

Santangelo L, Bordoni V, Montaldo C, Cimini E, Zingoni A, Battistelli C, D'Offizi G, Capobianchi MR, Santoni A, Tripodi M, Agrati C.

Liver Int. 2018 Jan 22. doi: 10.1111/liv.13700. [Epub ahead of print]

PMID:
29359389
14.

Dysfunctional telomeres and hematological disorders.

Fiorini E, Santoni A, Colla S.

Differentiation. 2018 Mar - Apr;100:1-11. doi: 10.1016/j.diff.2018.01.001. Epub 2018 Jan 4. Review.

PMID:
29331736
15.

Mandatory vaccination in Italy: Time for engagement of immunologists.

Mantovani A, Santoni A.

Eur J Immunol. 2018 Jan;48(1):12-14. doi: 10.1002/eji.201870016. No abstract available.

PMID:
29318660
16.

Environmental stimuli shape microglial plasticity in glioma.

Garofalo S, Porzia A, Mainiero F, Di Angelantonio S, Cortese B, Basilico B, Pagani F, Cignitti G, Chece G, Maggio R, Tremblay ME, Savage J, Bisht K, Esposito V, Bernardini G, Seyfried T, Mieczkowski J, Stepniak K, Kaminska B, Santoni A, Limatola C.

Elife. 2017 Dec 29;6. pii: e33415. doi: 10.7554/eLife.33415.

17.

Effect of once-daily, modified-release hydrocortisone versus standard glucocorticoid therapy on metabolism and innate immunity in patients with adrenal insufficiency (DREAM): a single-blind, randomised controlled trial.

Isidori AM, Venneri MA, Graziadio C, Simeoli C, Fiore D, Hasenmajer V, Sbardella E, Gianfrilli D, Pozza C, Pasqualetti P, Morrone S, Santoni A, Naro F, Colao A, Pivonello R, Lenzi A.

Lancet Diabetes Endocrinol. 2018 Mar;6(3):173-185. doi: 10.1016/S2213-8587(17)30398-4. Epub 2017 Dec 8.

PMID:
29229498
18.

How Mucosal Epithelia Deal with Stress: Role of NKG2D/NKG2D Ligands during Inflammation.

Antonangeli F, Soriani A, Cerboni C, Sciumè G, Santoni A.

Front Immunol. 2017 Nov 20;8:1583. doi: 10.3389/fimmu.2017.01583. eCollection 2017. Review.

19.

IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity.

Molgora M, Bonavita E, Ponzetta A, Riva F, Barbagallo M, Jaillon S, Popović B, Bernardini G, Magrini E, Gianni F, Zelenay S, Jonjić S, Santoni A, Garlanda C, Mantovani A.

Nature. 2017 Nov 2;551(7678):110-114. doi: 10.1038/nature24293. Epub 2017 Oct 25.

20.

Natural Killer Cell Response to Chemotherapy-Stressed Cancer Cells: Role in Tumor Immunosurveillance.

Zingoni A, Fionda C, Borrelli C, Cippitelli M, Santoni A, Soriani A.

Front Immunol. 2017 Sep 25;8:1194. doi: 10.3389/fimmu.2017.01194. eCollection 2017. Review.

21.

Reconstitution of multifunctional CD56lowCD16low natural killer cell subset in children with acute leukemia given α/β T cell-depleted HLA-haploidentical haematopoietic stem cell transplantation.

Helena S, Paolo N, Giovanna P, Cinzia F, Daria P, Letizia PB, Pietro M, Franco L, Santoni A, Gismondi A.

Oncoimmunology. 2017 Aug 10;6(9):e1342024. doi: 10.1080/2162402X.2017.1342024. eCollection 2017. Erratum in: Oncoimmunology. 2017 Oct 16;6(10 ):e1392418.

22.

Innate immune activating ligand SUMOylation affects tumor cell recognition by NK cells.

Zitti B, Molfetta R, Fionda C, Quatrini L, Stabile H, Lecce M, de Turris V, Ricciardi MR, Petrucci MT, Cippitelli M, Gismondi A, Santoni A, Paolini R.

Sci Rep. 2017 Sep 5;7(1):10445. doi: 10.1038/s41598-017-10403-0.

23.

Multicolor flow cytometric analysis of TLR2 and TLR9 expression and function in NK cells from patients with ANCA-associated vasculitis.

Scrivo R, Peruzzi G, Gattamelata A, Gross CC, Carletti R, Di Gioia C, Brandt J, Priori R, Morrone S, Santoni A, Valesini G.

Cytometry B Clin Cytom. 2018 May;94(3):412-422. doi: 10.1002/cyto.b.21586. Epub 2017 Aug 29.

PMID:
28834234
24.

Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis.

Molfetta R, Quatrini L, Santoni A, Paolini R.

Int J Mol Sci. 2017 Aug 2;18(8). pii: E1677. doi: 10.3390/ijms18081677. Review.

25.

Identification of a Genetic Variation in ERAP1 Aminopeptidase that Prevents Human Cytomegalovirus miR-UL112-5p-Mediated Immunoevasion.

Romania P, Cifaldi L, Pignoloni B, Starc N, D'Alicandro V, Melaiu O, Li Pira G, Giorda E, Carrozzo R, Bergvall M, Bergström T, Alfredsson L, Olsson T, Kockum I, Seppälä I, Lehtimäki T, Hurme MA, Hengel H, Santoni A, Cerboni C, Locatelli F, D'Amato M, Fruci D.

Cell Rep. 2017 Jul 25;20(4):846-853. doi: 10.1016/j.celrep.2017.06.084.

26.

Peripheral blood T cell alterations in newly diagnosed diffuse large B cell lymphoma patients and their long-term dynamics upon rituximab-based chemoimmunotherapy.

Battella S, Cox MC, La Scaleia R, Di Napoli A, Di Landro F, Porzia A, Franchitti L, Mainiero F, Ruco L, Monarca B, Santoni A, Palmieri G.

Cancer Immunol Immunother. 2017 Oct;66(10):1295-1306. doi: 10.1007/s00262-017-2026-7. Epub 2017 May 29.

PMID:
28555258
27.

Docosahexaenoic acid (DHA) promotes immunogenic apoptosis in human multiple myeloma cells, induces autophagy and inhibits STAT3 in both tumor and dendritic cells.

D'Eliseo D, Di Renzo L, Santoni A, Velotti F.

Genes Cancer. 2017 Jan;8(1-2):426-437. doi: 10.18632/genesandcancer.131.

28.

Obinutuzumab-mediated high-affinity ligation of FcγRIIIA/CD16 primes NK cells for IFNγ production.

Capuano C, Pighi C, Molfetta R, Paolini R, Battella S, Palmieri G, Giannini G, Belardinilli F, Santoni A, Galandrini R.

Oncoimmunology. 2017 Feb 10;6(3):e1290037. doi: 10.1080/2162402X.2017.1290037. eCollection 2017.

29.

Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: Role of HSP70/TLR2/NF-kB axis.

Vulpis E, Cecere F, Molfetta R, Soriani A, Fionda C, Peruzzi G, Caracciolo G, Palchetti S, Masuelli L, Simonelli L, D'Oro U, Abruzzese MP, Petrucci MT, Ricciardi MR, Paolini R, Cippitelli M, Santoni A, Zingoni A.

Oncoimmunology. 2017 Jan 13;6(3):e1279372. doi: 10.1080/2162402X.2017.1279372. eCollection 2017.

30.

Role of Distinct Natural Killer Cell Subsets in Anticancer Response.

Stabile H, Fionda C, Gismondi A, Santoni A.

Front Immunol. 2017 Mar 16;8:293. doi: 10.3389/fimmu.2017.00293. eCollection 2017. Review.

31.

High expression levels of IP10/CXCL10 are associated with modulation of the natural killer cell compartment in multiple myeloma.

Bernardini G, Vulpis E, Bonanni V, Stabile H, Ricciardi MR, Petrucci MT, Gismondi A, Santoni A, Zingoni A.

Leuk Lymphoma. 2017 Oct;58(10):2493-2496. doi: 10.1080/10428194.2017.1295144. Epub 2017 Feb 28. No abstract available.

PMID:
28278706
32.

The Multifunctional Role of the Chemokine System in Arthritogenic Processes.

Bernardini G, Benigni G, Scrivo R, Valesini G, Santoni A.

Curr Rheumatol Rep. 2017 Mar;19(3):11. doi: 10.1007/s11926-017-0635-y. Review.

PMID:
28265846
33.

GM-CSF Inhibits c-Kit and SCF Expression by Bone Marrow-Derived Dendritic Cells.

Barroeta Seijas AB, Simonetti S, Vitale S, Runci D, Quinci AC, Soriani A, Criscuoli M, Filippi I, Naldini A, Sacchetti FM, Tarantino U, Oliva F, Piccirilli E, Santoni A, Di Rosa F.

Front Immunol. 2017 Feb 16;8:147. doi: 10.3389/fimmu.2017.00147. eCollection 2017.

34.

p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells.

Soriani A, Borrelli C, Ricci B, Molfetta R, Zingoni A, Fionda C, Carnevale S, Abruzzese MP, Petrucci MT, Ricciardi MR, La Regina G, Di Cesare E, Lavia P, Silvestri R, Paolini R, Cippitelli M, Santoni A.

Oncoimmunology. 2016 Dec 2;6(1):e1264564. doi: 10.1080/2162402X.2016.1264564. eCollection 2017.

35.

CXCR3/CXCL10 Axis Regulates Neutrophil-NK Cell Cross-Talk Determining the Severity of Experimental Osteoarthritis.

Benigni G, Dimitrova P, Antonangeli F, Sanseviero E, Milanova V, Blom A, van Lent P, Morrone S, Santoni A, Bernardini G.

J Immunol. 2017 Mar 1;198(5):2115-2124. doi: 10.4049/jimmunol.1601359. Epub 2017 Jan 20.

36.

Axitinib induces senescence-associated cell death and necrosis in glioma cell lines: The proteasome inhibitor, bortezomib, potentiates axitinib-induced cytotoxicity in a p21(Waf/Cip1) dependent manner.

Morelli MB, Amantini C, Nabissi M, Cardinali C, Santoni M, Bernardini G, Santoni A, Santoni G.

Oncotarget. 2017 Jan 10;8(2):3380-3395. doi: 10.18632/oncotarget.13769.

37.

Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay.

Abruzzese MP, Bilotta MT, Fionda C, Zingoni A, Soriani A, Vulpis E, Borrelli C, Zitti B, Petrucci MT, Ricciardi MR, Molfetta R, Paolini R, Santoni A, Cippitelli M.

J Hematol Oncol. 2016 Dec 1;9(1):134.

38.

Natural killer cell recognition of in vivo drug-induced senescent multiple myeloma cells.

Antonangeli F, Soriani A, Ricci B, Ponzetta A, Benigni G, Morrone S, Bernardini G, Santoni A.

Oncoimmunology. 2016 Aug 5;5(10):e1218105. eCollection 2016.

39.

Post-transcriptional regulation of 5'-untranslated regions of human Transient Receptor Potential Vanilloid type-1 (TRPV-1) channels: role in the survival of glioma patients.

Nabissi M, Morelli MB, Arcella A, Cardinali C, Santoni M, Bernardini G, Santoni A, Santoni G, Amantini C.

Oncotarget. 2016 Dec 6;7(49):81541-81554. doi: 10.18632/oncotarget.13132.

40.

NK cell effector functions in a Chédiak-Higashi patient undergoing cord blood transplantation: Effects of in vitro treatment with IL-2.

Cifaldi L, Pinto RM, Rana I, Caniglia M, Angioni A, Petrocchi S, Cancrini C, Cursi L, Palumbo G, Zingoni A, Gismondi A, Rossi P, Santoni A, Cerboni C.

Immunol Lett. 2016 Dec;180:46-53. doi: 10.1016/j.imlet.2016.10.009. Epub 2016 Nov 2.

PMID:
27816481
41.

Immunoregulatory and Effector Activities of Nitric Oxide and Reactive Nitrogen Species in Cancer.

Fionda C, Abruzzese MP, Santoni A, Cippitelli M.

Curr Med Chem. 2016;23(24):2618-2636. Review.

PMID:
27464520
42.

Dysregulation of Chemokine/Chemokine Receptor Axes and NK Cell Tissue Localization during Diseases.

Bernardini G, Antonangeli F, Bonanni V, Santoni A.

Front Immunol. 2016 Oct 6;7:402. eCollection 2016. Review.

43.

Distinct Roles for Human Cytomegalovirus Immediate Early Proteins IE1 and IE2 in the Transcriptional Regulation of MICA and PVR/CD155 Expression.

Pignoloni B, Fionda C, Dell'Oste V, Luganini A, Cippitelli M, Zingoni A, Landolfo S, Gribaudo G, Santoni A, Cerboni C.

J Immunol. 2016 Nov 15;197(10):4066-4078. Epub 2016 Oct 12.

44.

Regulation of NKG2D Expression and Signaling by Endocytosis.

Molfetta R, Quatrini L, Zitti B, Capuano C, Galandrini R, Santoni A, Paolini R.

Trends Immunol. 2016 Nov;37(11):790-802. doi: 10.1016/j.it.2016.08.015. Epub 2016 Sep 22. Review.

PMID:
27667711
45.

Elucidating the gut microbiome of ulcerative colitis: bifidobacteria as novel microbial biomarkers.

Duranti S, Gaiani F, Mancabelli L, Milani C, Grandi A, Bolchi A, Santoni A, Lugli GA, Ferrario C, Mangifesta M, Viappiani A, Bertoni S, Vivo V, Serafini F, Barbaro MR, Fugazza A, Barbara G, Gioiosa L, Palanza P, Cantoni AM, de'Angelis GL, Barocelli E, de'Angelis N, van Sinderen D, Ventura M, Turroni F.

FEMS Microbiol Ecol. 2016 Dec;92(12). pii: fiw191. doi: 10.1093/femsec/fiw191. Epub 2016 Sep 7.

PMID:
27604252
46.

Polyfunctional Melan-A-specific tumor-reactive CD8(+) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS.

Franzese O, Palermo B, Di Donna C, Sperduti I, Ferraresi V, Stabile H, Gismondi A, Santoni A, Nisticò P.

Oncoimmunology. 2016 Feb 1;5(5):e1114203. doi: 10.1080/2162402X.2015.1114203. eCollection 2016 May.

47.

Overexpression of transient receptor potential mucolipin-2 ion channels in gliomas: role in tumor growth and progression.

Morelli MB, Nabissi M, Amantini C, Tomassoni D, Rossi F, Cardinali C, Santoni M, Arcella A, Oliva MA, Santoni A, Polidori C, Mariani MP, Santoni G.

Oncotarget. 2016 Jul 12;7(28):43654-43668. doi: 10.18632/oncotarget.9661.

48.

Epitelial-to-mesenchimal transition and invasion are upmodulated by tumor-expressed granzyme B and inhibited by docosahexaenoic acid in human colorectal cancer cells.

D'Eliseo D, Di Rocco G, Loria R, Soddu S, Santoni A, Velotti F.

J Exp Clin Cancer Res. 2016 Feb 2;35:24. doi: 10.1186/s13046-016-0302-6.

49.

Targeting NKG2D and NKp30 Ligands Shedding to Improve NK Cell-Based Immunotherapy.

Zingoni A, Vulpis E, Nardone I, Soriani A, Fionda C, Cippitelli M, Santoni A.

Crit Rev Immunol. 2016;36(6):445-460. doi: 10.1615/CritRevImmunol.2017020166.

PMID:
28845754
50.

Effector Functions of Natural Killer Cell Subsets in the Control of Hematological Malignancies.

Gismondi A, Stabile H, Nisti P, Santoni A.

Front Immunol. 2015 Nov 5;6:567. doi: 10.3389/fimmu.2015.00567. eCollection 2015. Review.

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