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Items: 35


High-Salt Diet Induces IL-17-Dependent Gut Inflammation and Exacerbates Colitis in Mice.

Aguiar SLF, Miranda MCG, Guimarães MAF, Santiago HC, Queiroz CP, Cunha PDS, Cara DC, Foureaux G, Ferreira AJ, Cardoso VN, Barros PA, Maioli TU, Faria AMC.

Front Immunol. 2018 Jan 15;8:1969. doi: 10.3389/fimmu.2017.01969. eCollection 2017.


The cytosolic sensor STING is required for intestinal homeostasis and control of inflammation.

Canesso MCC, Lemos L, Neves TC, Marim FM, Castro TBR, Veloso ÉS, Queiroz CP, Ahn J, Santiago HC, Martins FS, Alves-Silva J, Ferreira E, Cara DC, Vieira AT, Barber GN, Oliveira SC, Faria AMC.

Mucosal Immunol. 2018 May;11(3):820-834. doi: 10.1038/mi.2017.88. Epub 2017 Dec 20.


Obesity-induced diet leads to weight gain, systemic metabolic alterations, adipose tissue inflammation, hepatic steatosis, and oxidative stress in gerbils (Meriones unguiculatus).

Ventura LL, Fortes NC, Santiago HC, Caliari MV, Gomes MA, Oliveira DR.

PeerJ. 2017 Mar 2;5:e2967. doi: 10.7717/peerj.2967. eCollection 2017.


Human Helminths and Allergic Disease: The Hygiene Hypothesis and Beyond.

Santiago HC, Nutman TB.

Am J Trop Med Hyg. 2016 Oct 5;95(4):746-753. Epub 2016 Aug 29. Review.


Allergic Sensitization Underlies Hyperreactive Antigen-Specific CD4+ T Cell Responses in Coincident Filarial Infection.

Gazzinelli-Guimarães PH, Bonne-Année S, Fujiwara RT, Santiago HC, Nutman TB.

J Immunol. 2016 Oct 1;197(7):2772-9. doi: 10.4049/jimmunol.1600829. Epub 2016 Aug 26.


Trypanosoma cruzi Causes Paralyzing Systemic Necrotizing Vasculitis Driven by Pathogen-Specific Type I Immunity in Mice.

Roffê E, Marino APMP, Weaver J, Wan W, de Araújo FF, Hoffman V, Santiago HC, Murphy PM.

Infect Immun. 2016 Mar 24;84(4):1123-1136. doi: 10.1128/IAI.01497-15. Print 2016 Apr.


Molecular mimicry between cockroach and helminth glutathione S-transferases promotes cross-reactivity and cross-sensitization.

Santiago HC, LeeVan E, Bennuru S, Ribeiro-Gomes F, Mueller E, Wilson M, Wynn T, Garboczi D, Urban J, Mitre E, Nutman TB.

J Allergy Clin Immunol. 2012 Jul;130(1):248-56.e9. doi: 10.1016/j.jaci.2012.02.045. Epub 2012 Apr 25.


NADPH phagocyte oxidase knockout mice control Trypanosoma cruzi proliferation, but develop circulatory collapse and succumb to infection.

Santiago HC, Gonzalez Lombana CZ, Macedo JP, Utsch L, Tafuri WL, Campagnole-Santos MJ, Alves RO, Alves-Filho JC, Romanha AJ, Cunha FQ, Teixeira MM, Radi R, Vieira LQ.

PLoS Negl Trop Dis. 2012;6(2):e1492. doi: 10.1371/journal.pntd.0001492. Epub 2012 Feb 14.


IL-10 limits parasite burden and protects against fatal myocarditis in a mouse model of Trypanosoma cruzi infection.

Roffê E, Rothfuchs AG, Santiago HC, Marino AP, Ribeiro-Gomes FL, Eckhaus M, Antonelli LR, Murphy PM.

J Immunol. 2012 Jan 15;188(2):649-60. doi: 10.4049/jimmunol.1003845. Epub 2011 Dec 12.


Structural and immunologic cross-reactivity among filarial and mite tropomyosin: implications for the hygiene hypothesis.

Santiago HC, Bennuru S, Boyd A, Eberhard M, Nutman TB.

J Allergy Clin Immunol. 2011 Feb;127(2):479-86. doi: 10.1016/j.jaci.2010.11.007. Epub 2010 Dec 24.


Role of CCL3/MIP-1alpha and CCL5/RANTES during acute Trypanosoma cruzi infection in rats.

Roffê E, Oliveira F, Souza AL, Pinho V, Souza DG, Souza PR, Russo RC, Santiago HC, Romanha AJ, Tanowitz HB, Valenzuela JG, Teixeira MM.

Microbes Infect. 2010 Aug;12(8-9):669-76. doi: 10.1016/j.micinf.2010.04.011. Epub 2010 May 7.


The flavonoid dioclein reduces the production of pro-inflammatory mediators in vitro by inhibiting PDE4 activity and scavenging reactive oxygen species.

Guabiraba R, Campanha-Rodrigues AL, Souza AL, Santiago HC, Lugnier C, Alvarez-Leite J, Lemos VS, Teixeira MM.

Eur J Pharmacol. 2010 May 10;633(1-3):85-92. doi: 10.1016/j.ejphar.2010.01.021. Epub 2010 Feb 10.


Necator americanus infection: a possible cause of altered dendritic cell differentiation and eosinophil profile in chronically infected individuals.

Fujiwara RT, Cançado GG, Freitas PA, Santiago HC, Massara CL, Dos Santos Carvalho O, Corrêa-Oliveira R, Geiger SM, Bethony J.

PLoS Negl Trop Dis. 2009;3(3):e399. doi: 10.1371/journal.pntd.0000399. Epub 2009 Mar 24.


Chronic antigen ingestion protects ovalbumin sensitized mice from severe manifestation of Leishmania major infection.

Saldanha JC, Gargiulo DL, Dourado LP, Santiago HC, Menezes GB, Reis ML, Tafuri WL, Teixeira MM, Vieira LQ, Cara DC.

Parasite Immunol. 2008 Nov-Dec;30(11-12):646-9. doi: 10.1111/j.1365-3024.2008.01063.x.


Influence of low-density lipoprotein (LDL) receptor on lipid composition, inflammation and parasitism during Toxoplasma gondii infection.

Portugal LR, Fernandes LR, Pietra Pedroso VS, Santiago HC, Gazzinelli RT, Alvarez-Leite JI.

Microbes Infect. 2008 Mar;10(3):276-84. doi: 10.1016/j.micinf.2007.12.001. Epub 2007 Dec 8.


Early infection with Leishmania major restrains pathogenic response to Leishmania amazonensis and parasite growth.

González-Lombana CZ, Santiago HC, Macedo JP, Seixas VA, Russo RC, Tafuri WL, Afonso LC, Vieira LQ.

Acta Trop. 2008 Apr;106(1):27-38. doi: 10.1016/j.actatropica.2007.12.012. Epub 2008 Jan 15.


The IFN-inducible GTPase LRG47 (Irgm1) negatively regulates TLR4-triggered proinflammatory cytokine production and prevents endotoxemia.

Bafica A, Feng CG, Santiago HC, Aliberti J, Cheever A, Thomas KE, Taylor GA, Vogel SN, Sher A.

J Immunol. 2007 Oct 15;179(8):5514-22.


A DNA vaccine encoding CCL4/MIP-1beta enhances myocarditis in experimental Trypanosoma cruzi infection in rats.

Roffê E, Souza AL, Caetano BC, Machado PP, Barcelos LS, Russo RC, Santiago HC, Souza DG, Pinho V, Tanowitz HB, Camargos ER, Bruña-Romero O, Teixeira MM.

Microbes Infect. 2006 Oct;8(12-13):2745-55. Epub 2006 Aug 30.


Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection.

Bafica A, Santiago HC, Goldszmid R, Ropert C, Gazzinelli RT, Sher A.

J Immunol. 2006 Sep 15;177(6):3515-9.


Platelet activating factor receptor-deficient mice present delayed interferon-gamma upregulation and high susceptibility to Leishmania amazonensis infection.

Santiago HC, Braga Pires MF, Souza DG, Roffê E, Côrtes DF, Tafuri WL, Teixeira MM, Vieira LQ.

Microbes Infect. 2006 Sep;8(11):2569-77. Epub 2006 Aug 7.


Mice deficient in LRG-47 display enhanced susceptibility to Trypanosoma cruzi infection associated with defective hemopoiesis and intracellular control of parasite growth.

Santiago HC, Feng CG, Bafica A, Roffe E, Arantes RM, Cheever A, Taylor G, Vieira LQ, Aliberti J, Gazzinelli RT, Sher A.

J Immunol. 2005 Dec 15;175(12):8165-72. Erratum in: J Immunol. 2006 Mar 15;176(6):3840. Vierira, Leda Q [corrected to Vieira, Leda Q].


Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major.

Santiago HC, Oliveira CF, Santiago L, Ferraz FO, de Souza D G, de-Freitas LA, Afonso LC, Teixeira MM, Gazzinelli RT, Vieira LQ.

Infect Immun. 2004 Aug;72(8):4918-23.


Infection with Toxoplasma gondii increases atherosclerotic lesion in ApoE-deficient mice.

Portugal LR, Fernandes LR, Cesar GC, Santiago HC, Oliveira DR, Silva NM, Silva AA, Lannes-Vieira J, Arantes RM, Gazzinelli RT, Alvarez-Leite JI.

Infect Immun. 2004 Jun;72(6):3571-6.


Monocyte chemoattractant protein-1 involvement in the alpha-tocopherol-induced reduction of atherosclerotic lesions in apolipoprotein E knockout mice.

Peluzio MC, Miguel E Jr, Drumond TC, César GC, Santiago HC, Teixeira MM, Vieira EC, Arantes RM, Alvarez-Leite JI.

Br J Nutr. 2003 Jul;90(1):3-11.


Combined interleukin-12 and topical chemotherapy for established Leishmaniasis drastically reduces tissue parasitism and relapses in susceptible mice.

Fernandes AP, Carvalho FA, Tavares CA, Santiago HC, Castro GA, Tafuri WL, Ferreira LA, Gazzinelli RT.

J Infect Dis. 2001 Jun 1;183(11):1646-52. Epub 2001 May 9.


Leishmania sp: comparative study with Toxoplasma gondii and Trypanosoma cruzi in their ability to initialize IL-12 and IFN-gamma synthesis.

Oliveira MA, Santiago HC, Lisboa CR, Ceravollo IP, Trinchieri G, Gazzinelli RT, Vieira LQ.

Exp Parasitol. 2000 Jun;95(2):96-105.


Coinfection with Toxoplasma gondii inhibits antigen-specific Th2 immune responses, tissue inflammation, and parasitism in BALB/c mice infected with Leishmania major.

Santiago HC, Oliveira MA, Bambirra EA, Faria AM, Afonso LC, Vieira LQ, Gazzinelli RT.

Infect Immun. 1999 Sep;67(9):4939-44.


Induction of cell-mediated immunity during early stages of infection with intracellular protozoa.

Gazzinelli RT, Talvani A, Camargo MM, Santiago HC, Oliveira MA, Vieira LQ, Martins GA, Aliberti JC, Silva JS.

Braz J Med Biol Res. 1998 Jan;31(1):89-104. Review.


Visual recognition memory in specific learning-disabled children.

Santiago HC, Matos I.

J Am Optom Assoc. 1994 Oct;65(10):690-700.


The recruitment and retention of disadvantaged and underrepresented groups in optometry.

Santiago HC.

J Am Optom Assoc. 1992 Nov;63(11):815-8. Review.


Memory processing of serial lists by pigeons, monkeys, and people.

Wright AA, Santiago HC, Sands SF, Kendrick DF, Cook RG.

Science. 1985 Jul 19;229(4710):287-9.


Monkey memory: same/different concept learning, serial probe acquisition, and probe delay effects.

Wright AA, Santiago HC, Sands SF.

J Exp Psychol Anim Behav Process. 1984 Oct;10(4):513-29.


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