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Items: 28

1.

Extracellular signal-regulated kinase-1 phosphorylates early growth response-1 at serine 26.

Santiago FS, Sanchez-Guerrero E, Zhang G, Zhong L, Raftery MJ, Khachigian LM.

Biochem Biophys Res Commun. 2019 Mar 12;510(3):345-351. doi: 10.1016/j.bbrc.2019.01.019. Epub 2019 Jan 31.

PMID:
30711252
2.

Developing Neolignans as Proangiogenic Agents: Stereoselective Total Syntheses and Preliminary Biological Evaluations of the Four Guaiacylglycerol 8-O-4'-Coniferyl Ethers.

Buckler JN, Banwell MG, Kordbacheh F, Parish CR, Santiago FS, Khachigian LM.

ACS Omega. 2017 Oct 31;2(10):7375-7388. doi: 10.1021/acsomega.7b01459. Epub 2017 Oct 30.

3.

DNAzyme targeting c-jun suppresses skin cancer growth.

Cai H, Santiago FS, Prado-Lourenco L, Wang B, Patrikakis M, Davenport MP, Maghzal GJ, Stocker R, Parish CR, Chong BH, Lieschke GJ, Wong TW, Chesterman CN, Francis DJ, Moloney FJ, Barnetson RS, Halliday GM, Khachigian LM.

Sci Transl Med. 2012 Jun 20;4(139):139ra82. doi: 10.1126/scitranslmed.3003960.

4.

Yin Yang-1 inhibits tumor cell growth and inhibits p21WAF1/Cip1 complex formation with cdk4 and cyclin D1.

Ishii H, Hulett MD, Li JM, Santiago FS, Parish CR, Khachigian LM.

Int J Oncol. 2012 May;40(5):1575-80. doi: 10.3892/ijo.2012.1362. Epub 2012 Feb 9.

PMID:
22322893
5.

Interplay between heme oxygenase-1 and the multifunctional transcription factor yin yang 1 in the inhibition of intimal hyperplasia.

Beck K, Wu BJ, Ni J, Santiago FS, Malabanan KP, Li C, Wang Y, Khachigian LM, Stocker R.

Circ Res. 2010 Dec 10;107(12):1490-7. doi: 10.1161/CIRCRESAHA.110.231985. Epub 2010 Oct 28.

PMID:
21030713
6.

Macrophage migration inhibitory factor increases leukocyte-endothelial interactions in human endothelial cells via promotion of expression of adhesion molecules.

Cheng Q, McKeown SJ, Santos L, Santiago FS, Khachigian LM, Morand EF, Hickey MJ.

J Immunol. 2010 Jul 15;185(2):1238-47. doi: 10.4049/jimmunol.0904104. Epub 2010 Jun 16. Erratum in: J Immunol. 2010 Oct 15;185(8):4959.

7.

Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription.

Wang B, Chen J, Santiago FS, Janes M, Kavurma MM, Chong BH, Pimanda JE, Khachigian LM.

Arterioscler Thromb Vasc Biol. 2010 Mar;30(3):536-45. doi: 10.1161/ATVBAHA.109.193821. Epub 2009 Dec 17.

PMID:
20018936
8.

Angiotensin II-inducible platelet-derived growth factor-D transcription requires specific Ser/Thr residues in the second zinc finger region of Sp1.

Tan NY, Midgley VC, Kavurma MM, Santiago FS, Luo X, Peden R, Fahmy RG, Berndt MC, Molloy MP, Khachigian LM.

Circ Res. 2008 Feb 29;102(4):e38-51. doi: 10.1161/CIRCRESAHA.107.167395. Epub 2008 Feb 7.

PMID:
18258854
9.

Yin Yang-1 inhibits vascular smooth muscle cell growth and intimal thickening by repressing p21WAF1/Cip1 transcription and p21WAF1/Cip1-Cdk4-cyclin D1 assembly.

Santiago FS, Ishii H, Shafi S, Khurana R, Kanellakis P, Bhindi R, Ramirez MJ, Bobik A, Martin JF, Chesterman CN, Zachary IC, Khachigian LM.

Circ Res. 2007 Jul 20;101(2):146-55. Epub 2007 Jun 7.

PMID:
17556661
10.

Inducible platelet-derived growth factor D-chain expression by angiotensin II and hydrogen peroxide involves transcriptional regulation by Ets-1 and Sp1.

Liu MY, Eyries M, Zhang C, Santiago FS, Khachigian LM.

Blood. 2006 Mar 15;107(6):2322-9. Epub 2005 Sep 27.

11.
12.

Regulation of inducible heparanase gene transcription in activated T cells by early growth response 1.

de Mestre AM, Khachigian LM, Santiago FS, Staykova MA, Hulett MD.

J Biol Chem. 2003 Dec 12;278(50):50377-85. Epub 2003 Sep 30.

13.

Blockade of vascular smooth muscle cell proliferation and intimal thickening after balloon injury by the sulfated oligosaccharide PI-88: phosphomannopentaose sulfate directly binds FGF-2, blocks cellular signaling, and inhibits proliferation.

Francis DJ, Parish CR, McGarry M, Santiago FS, Lowe HC, Brown KJ, Bingley JA, Hayward IP, Cowden WB, Campbell JH, Campbell GR, Chesterman CN, Khachigian LM.

Circ Res. 2003 May 2;92(8):e70-7. Epub 2003 Apr 10.

PMID:
12690039
14.

Nucleic acid based strategies as potential therapeutic tools: mechanistic considerations and implications to restenosis.

Santiago FS, Khachigian LM.

J Mol Med (Berl). 2001 Dec;79(12):695-706. Epub 2001 Sep 22. Review.

PMID:
11862313
15.
16.

Induction of the transcriptional repressor Yin Yang-1 by vascular cell injury. Autocrine/paracrine role of endogenous fibroblast growth factor-2.

Santiago FS, Lowe HC, Bobryshev YV, Khachigian LM.

J Biol Chem. 2001 Nov 2;276(44):41143-9. Epub 2001 Aug 3.

17.

Sp1 phosphorylation regulates apoptosis via extracellular FasL-Fas engagement.

Kavurma MM, Santiago FS, Bonfoco E, Khachigian LM.

J Biol Chem. 2001 Feb 16;276(7):4964-71. Epub 2000 Oct 26.

18.

New DNA enzyme targeting Egr-1 mRNA inhibits vascular smooth muscle proliferation and regrowth after injury.

Santiago FS, Lowe HC, Kavurma MM, Chesterman CN, Baker A, Atkins DG, Khachigian LM.

Nat Med. 1999 Dec;5(12):1438. No abstract available.

PMID:
10581092
19.

New DNA enzyme targeting Egr-1 mRNA inhibits vascular smooth muscle proliferation and regrowth after injury.

Santiago FS, Lowe HC, Kavurma MM, Chesterman CN, Baker A, Atkins DG, Khachigian LM.

Nat Med. 1999 Nov;5(11):1264-9. Erratum in: Nat Med 1999 Dec;5(12):1438.

PMID:
10545992
20.

Vascular smooth muscle cells express the transcriptional corepressor NAB2 in response to injury.

Silverman ES, Khachigian LM, Santiago FS, Williams AJ, Lindner V, Collins T.

Am J Pathol. 1999 Oct;155(4):1311-7.

21.
22.

GC factor 2 represses platelet-derived growth factor A-chain gene transcription and is itself induced by arterial injury.

Khachigian LM, Santiago FS, Rafty LA, Chan OL, Delbridge GJ, Bobik A, Collins T, Johnson AC.

Circ Res. 1999 Jun 11;84(11):1258-67.

PMID:
10364563
23.

Early growth response factor-1 induction by injury is triggered by release and paracrine activation by fibroblast growth factor-2.

Santiago FS, Lowe HC, Day FL, Chesterman CN, Khachigian LM.

Am J Pathol. 1999 Mar;154(3):937-44.

24.

Detection of K-ras point mutation by enriched PCR-colorimetric plate assay.

Santiago FS, Todd AV, Hawkins NJ, Ward RL.

Mol Cell Probes. 1997 Feb;11(1):33-8.

PMID:
9076712
25.

In vitro activity of minimised hammerhead ribozymes.

Hendry P, McCall MJ, Santiago FS, Jennings PA.

Nucleic Acids Res. 1995 Oct 11;23(19):3922-7.

26.

A ribozyme with DNA in the hybridising arms displays enhanced cleavage ability.

Hendry P, McCall MJ, Santiago FS, Jennings PA.

Nucleic Acids Res. 1992 Nov 11;20(21):5737-41.

27.

High level expression and purification of dthymidine diphospho-D-glucose 4,6-dehydratase (rfbB) from Salmonella serovar typhimurium LT2.

Romana LK, Santiago FS, Reeves PR.

Biochem Biophys Res Commun. 1991 Jan 31;174(2):846-52.

PMID:
1993076
28.

Nonnarcotic analgesia to simplify postpartum care.

SANTIAGO FS, DANFORTH DN.

Obstet Gynecol. 1959 Jan;14(1):22-3. No abstract available.

PMID:
13623139

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