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Items: 1 to 50 of 148

1.

Neuropathology of a Case With Fatal CAR T-Cell-Associated Cerebral Edema.

Torre M, Solomon IH, Sutherland CL, Nikiforow S, DeAngelo DJ, Stone RM, Vaitkevicius H, Galinsky IA, Padera RF, Trede N, Santagata S.

J Neuropathol Exp Neurol. 2018 Jul 6. doi: 10.1093/jnen/nly064. [Epub ahead of print]

PMID:
30060228
2.

Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes.

Lin JR, Izar B, Wang S, Yapp C, Mei S, Shah PM, Santagata S, Sorger PK.

Elife. 2018 Jul 11;7. pii: e31657. doi: 10.7554/eLife.31657.

3.

Meningioma transcription factors link cell lineage with systemic metabolic cues.

Du Z, Brewster R, Merrill PH, Chmielecki J, Francis J, Aizer A, Abedalthagafi M, Sholl LM, Geffers L, Alexander B, Santagata S.

Neuro Oncol. 2018 Apr 12. doi: 10.1093/neuonc/noy057. [Epub ahead of print]

PMID:
29660031
4.

Multiplexed immunofluorescence reveals potential PD-1/PD-L1 pathway vulnerabilities in craniopharyngioma.

Coy S, Rashid R, Lin JR, Du Z, Donson AM, Hankinson TC, Foreman NK, Manley PE, Kieran MW, Reardon DA, Sorger PK, Santagata S.

Neuro Oncol. 2018 Jul 5;20(8):1101-1112. doi: 10.1093/neuonc/noy035.

PMID:
29509940
5.

Orbital leiomyosarcoma metastasis presenting prior to diagnosis of the primary tumor.

Rasool N, Lefebvre DR, Latina MA, Dunn IF, Santagata S, Freitag SK, Cestari DM.

Digit J Ophthalmol. 2017 Dec 31;23(4):22-26. doi: 10.5693/djo.02.2017.02.004. eCollection 2017.

6.

Uncovering the links between systemic hormones and oncogenic signaling in the pathogenesis of meningioma.

Du Z, Santagata S.

Ann Oncol. 2018 Mar 1;29(3):537-540. doi: 10.1093/annonc/mdy010. No abstract available.

PMID:
29346520
7.

A case of molecularly profiled extraneural medulloblastoma metastases in a child.

Mobark NA, Al-Harbi M, Mosleh O, Santagata S, Snuderl M, Abedalthagafi M.

BMC Med Genet. 2018 Jan 17;19(1):10. doi: 10.1186/s12881-018-0526-8.

8.

Erratum: Genomic landscape of high-grade meningiomas.

Bi WL, Greenwald NF, Abedalthagafi M, Wala J, Gibson WJ, Agarwalla PK, Horowitz P, Schumacher SE, Esaulova E, Mei Y, Chevalier A, A Ducar M, Thorner AR, van Hummelen P, O Stemmer-Rachamimov A, Artyomov M, Al-Mefty O, Dunn GP, Santagata S, Dunn IF, Beroukhim R.

NPJ Genom Med. 2017 Sep 4;2:26. doi: 10.1038/s41525-017-0023-6. eCollection 2017.

9.

Radiographic prediction of meningioma grade by semantic and radiomic features.

Coroller TP, Bi WL, Huynh E, Abedalthagafi M, Aizer AA, Greenwald NF, Parmar C, Narayan V, Wu WW, Miranda de Moura S, Gupta S, Beroukhim R, Wen PY, Al-Mefty O, Dunn IF, Santagata S, Alexander BM, Huang RY, Aerts HJWL.

PLoS One. 2017 Nov 16;12(11):e0187908. doi: 10.1371/journal.pone.0187908. eCollection 2017.

10.

Targeting CXCR4 reverts the suppressive activity of T-regulatory cells in renal cancer.

Santagata S, Napolitano M, D'Alterio C, Desicato S, Maro SD, Marinelli L, Fragale A, Buoncervello M, Persico F, Gabriele L, Novellino E, Longo N, Pignata S, Perdonà S, Scala S.

Oncotarget. 2017 Aug 19;8(44):77110-77120. doi: 10.18632/oncotarget.20363. eCollection 2017 Sep 29.

11.

Osteoglycin promotes meningioma development through downregulation of NF2 and activation of mTOR signaling.

Mei Y, Du Z, Hu C, Greenwald NF, Abedalthagafi M, Agar NYR, Dunn GP, Bi WL, Santagata S, Dunn IF.

Cell Commun Signal. 2017 Sep 18;15(1):34. doi: 10.1186/s12964-017-0189-7.

12.

Nuclear CRX and FOXJ1 Expression Differentiates Non-Germ Cell Pineal Region Tumors and Supports the Ependymal Differentiation of Papillary Tumor of the Pineal Region.

Coy S, Dubuc AM, Dahiya S, Ligon KL, Vasiljevic A, Santagata S.

Am J Surg Pathol. 2017 Oct;41(10):1410-1421. doi: 10.1097/PAS.0000000000000903.

PMID:
28719464
13.

Genomic landscape of high-grade meningiomas.

Bi WL, Greenwald NF, Abedalthagafi M, Wala J, Gibson WJ, Agarwalla PK, Horowitz P, Schumacher SE, Esaulova E, Mei Y, Chevalier A, Ducar M, Thorner AR, van Hummelen P, Stemmer-Rachamimov A, Artyomov M, Al-Mefty O, Dunn GP, Santagata S, Dunn IF, Beroukhim R.

NPJ Genom Med. 2017;2. pii: 15. doi: 10.1038/s41525-017-0014-7. Epub 2017 Apr 26. Erratum in: NPJ Genom Med. 2017 Sep 4;2:26.

14.

A novel CXCR4-targeted near-infrared (NIR) fluorescent probe (Peptide R-NIR750) specifically detects CXCR4 expressing tumors.

Santagata S, Portella L, Napolitano M, Greco A, D'Alterio C, Barone MV, Luciano A, Gramanzini M, Auletta L, Arra C, Zannetti A, Scala S.

Sci Rep. 2017 May 31;7(1):2554. doi: 10.1038/s41598-017-02818-6.

15.

Altered tetrahydrobiopterin metabolism in patients with phenylalanine hydroxylase deficiency.

Nardecchia F, Chiarotti F, Carducci C, Santagata S, Valentini G, Angeloni A, Blau N, Leuzzi V.

Eur J Pediatr. 2017 Jul;176(7):917-924. doi: 10.1007/s00431-017-2932-x. Epub 2017 May 24.

PMID:
28540433
16.

Epigenome-wide association study in hepatocellular carcinoma: Identification of stochastic epigenetic mutations through an innovative statistical approach.

Gentilini D, Scala S, Gaudenzi G, Garagnani P, Capri M, Cescon M, Grazi GL, Bacalini MG, Pisoni S, Dicitore A, Circelli L, Santagata S, Izzo F, Di Blasio AM, Persani L, Franceschi C, Vitale G.

Oncotarget. 2017 Jun 27;8(26):41890-41902. doi: 10.18632/oncotarget.17462.

17.

Clinical Identification of Oncogenic Drivers and Copy-Number Alterations in Pituitary Tumors.

Bi WL, Greenwald NF, Ramkissoon SH, Abedalthagafi M, Coy SM, Ligon KL, Mei Y, MacConaill L, Ducar M, Min L, Santagata S, Kaiser UB, Beroukhim R, Laws ER Jr, Dunn IF.

Endocrinology. 2017 Jul 1;158(7):2284-2291. doi: 10.1210/en.2016-1967.

18.

BAP1 mutations in high-grade meningioma: implications for patient care.

Shankar GM, Santagata S.

Neuro Oncol. 2017 Oct 19;19(11):1447-1456. doi: 10.1093/neuonc/nox094. Review.

PMID:
28482042
19.

Fatal Eastern Equine Encephalitis in a Patient on Maintenance Rituximab: A Case Report.

Solomon IH, Ciarlini PDSC, Santagata S, Ahmed AA, De Girolami U, Prasad S, Mukerji SS.

Open Forum Infect Dis. 2017 Feb 12;4(1):ofx021. doi: 10.1093/ofid/ofx021. eCollection 2017 Winter.

20.

Electrostatically stabilized hybrids of carbon and maghemite nanoparticles: electrochemical study and application.

Baratella D, Magro M, Jakubec P, Bonaiuto E, de Almeida Roger J, Gerotto E, Zoppellaro G, Tucek J, Safarova KC, Zbořil R, Cecconello A, Willner I, Santagata S, Sambo P, Vianello F.

Phys Chem Chem Phys. 2017 May 10;19(18):11668-11677. doi: 10.1039/c7cp01486d.

PMID:
28435954
21.

Clinical and radiographic response following targeting of BCAN-NTRK1 fusion in glioneuronal tumor.

Alvarez-Breckenridge C, Miller JJ, Nayyar N, Gill CM, Kaneb A, D'Andrea M, Le LP, Lee J, Cheng J, Zheng Z, Butler WE, Multani P, Chow Maneval E, Ha Paek S, Toyota BD, Dias-Santagata D, Santagata S, Romero J, Shaw AT, Farago AF, Yip S, Cahill DP, Batchelor TT, Iafrate AJ, Brastianos PK.

NPJ Precis Oncol. 2017 Mar 20;1(1):5. doi: 10.1038/s41698-017-0009-y. eCollection 2017.

22.

Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas.

Shankar GM, Abedalthagafi M, Vaubel RA, Merrill PH, Nayyar N, Gill CM, Brewster R, Bi WL, Agarwalla PK, Thorner AR, Reardon DA, Al-Mefty O, Wen PY, Alexander BM, van Hummelen P, Batchelor TT, Ligon KL, Ligon AH, Meyerson M, Dunn IF, Beroukhim R, Louis DN, Perry A, Carter SL, Giannini C, Curry WT Jr, Cahill DP, Barker FG 2nd, Brastianos PK, Santagata S.

Neuro Oncol. 2017 Apr 1;19(4):535-545. doi: 10.1093/neuonc/now235.

23.

CXCR4-CXCL12-CXCR7, TLR2-TLR4, and PD-1/PD-L1 in colorectal cancer liver metastases from neoadjuvant-treated patients.

D'Alterio C, Nasti G, Polimeno M, Ottaiano A, Conson M, Circelli L, Botti G, Scognamiglio G, Santagata S, De Divitiis C, Nappi A, Napolitano M, Tatangelo F, Pacelli R, Izzo F, Vuttariello E, Botti G, Scala S.

Oncoimmunology. 2016 Nov 29;5(12):e1254313. doi: 10.1080/2162402X.2016.1254313. eCollection 2016.

24.

Rapid Mass Spectrometry Imaging to Assess the Biochemical Profile of Pituitary Tissue for Potential Intraoperative Usage.

Huang KT, Ludy S, Calligaris D, Dunn IF, Laws E, Santagata S, Agar NY.

Adv Cancer Res. 2017;134:257-282. doi: 10.1016/bs.acr.2016.11.006. Epub 2016 Dec 28. Review.

PMID:
28110653
25.

Development of a new UPLC-ESI-MS/MS method for the determination of biopterin and neopterin in dried blood spot.

Santagata S, Di Carlo E, Carducci C, Leuzzi V, Angeloni A, Carducci C.

Clin Chim Acta. 2017 Mar;466:145-151. doi: 10.1016/j.cca.2017.01.019. Epub 2017 Jan 18.

PMID:
28109742
26.

Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors.

Ramkissoon SH, Bandopadhayay P, Hwang J, Ramkissoon LA, Greenwald NF, Schumacher SE, O'Rourke R, Pinches N, Ho P, Malkin H, Sinai C, Filbin M, Plant A, Bi WL, Chang MS, Yang E, Wright KD, Manley PE, Ducar M, Alexandrescu S, Lidov H, Delalle I, Goumnerova LC, Church AJ, Janeway KA, Harris MH, MacConaill LE, Folkerth RD, Lindeman NI, Stiles CD, Kieran MW, Ligon AH, Santagata S, Dubuc AM, Chi SN, Beroukhim R, Ligon KL.

Neuro Oncol. 2017 Jul 1;19(7):986-996. doi: 10.1093/neuonc/now294.

27.

Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers.

Tsvetkov P, Sokol E, Jin D, Brune Z, Thiru P, Ghandi M, Garraway LA, Gupta PB, Santagata S, Whitesell L, Lindquist S.

Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):382-387. doi: 10.1073/pnas.1619067114. Epub 2016 Dec 27.

28.

Potential evolution of neurosurgical treatment paradigms for craniopharyngioma based on genomic and transcriptomic characteristics.

Robinson LC, Santagata S, Hankinson TC.

Neurosurg Focus. 2016 Dec;41(6):E3. Review.

PMID:
27903126
29.

Diagnosis and management of craniopharyngiomas in the era of genomics and targeted therapy.

Martinez-Gutierrez JC, D'Andrea MR, Cahill DP, Santagata S, Barker FG 2nd, Brastianos PK.

Neurosurg Focus. 2016 Dec;41(6):E2. Review.

PMID:
27903124
30.

Targeted sequencing of SMO and AKT1 in anterior skull base meningiomas.

Strickland MR, Gill CM, Nayyar N, D'Andrea MR, Thiede C, Juratli TA, Schackert G, Borger DR, Santagata S, Frosch MP, Cahill DP, Brastianos PK, Barker FG 2nd.

J Neurosurg. 2017 Aug;127(2):438-444. doi: 10.3171/2016.8.JNS161076. Epub 2016 Nov 25.

PMID:
27885953
31.

Susan Lindquist (1949-2016).

Whitesell L, Santagata S.

Science. 2016 Nov 25;354(6315):974. No abstract available.

PMID:
27884995
32.

Treatment of brain metastases in the modern genomic era.

Dagogo-Jack I, Gill CM, Cahill DP, Santagata S, Brastianos PK.

Pharmacol Ther. 2017 Feb;170:64-72. doi: 10.1016/j.pharmthera.2016.10.011. Epub 2016 Oct 20. Review.

PMID:
27773784
33.

Landscape of Genomic Alterations in Pituitary Adenomas.

Bi WL, Horowitz P, Greenwald NF, Abedalthagafi M, Agarwalla PK, Gibson WJ, Mei Y, Schumacher SE, Ben-David U, Chevalier A, Carter S, Tiao G, Brastianos PK, Ligon AH, Ducar M, MacConaill L, Laws ER Jr, Santagata S, Beroukhim R, Dunn IF.

Clin Cancer Res. 2017 Apr 1;23(7):1841-1851. doi: 10.1158/1078-0432.CCR-16-0790. Epub 2016 Oct 5.

34.

Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors.

Mei Y, Bi WL, Greenwald NF, Du Z, Agar NY, Kaiser UB, Woodmansee WW, Reardon DA, Freeman GJ, Fecci PE, Laws ER Jr, Santagata S, Dunn GP, Dunn IF.

Oncotarget. 2016 Nov 22;7(47):76565-76576. doi: 10.18632/oncotarget.12088.

35.

Distinct patterns of primary and motile cilia in Rathke's cleft cysts and craniopharyngioma subtypes.

Coy S, Du Z, Sheu SH, Woo T, Rodriguez FJ, Kieran MW, Santagata S.

Mod Pathol. 2016 Dec;29(12):1446-1459. doi: 10.1038/modpathol.2016.153. Epub 2016 Aug 26.

36.

Checkpoint inhibition in meningiomas.

Bi WL, Wu WW, Santagata S, Reardon DA, Dunn IF.

Immunotherapy. 2016 Jun;8(6):721-31. doi: 10.2217/imt-2016-0017. Review.

PMID:
27197540
37.

Label-Free Neurosurgical Pathology with Stimulated Raman Imaging.

Lu FK, Calligaris D, Olubiyi OI, Norton I, Yang W, Santagata S, Xie XS, Golby AJ, Agar NY.

Cancer Res. 2016 Jun 15;76(12):3451-62. doi: 10.1158/0008-5472.CAN-16-0270. Epub 2016 Apr 12.

38.

MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.

Bandopadhayay P, Ramkissoon LA, Jain P, Bergthold G, Wala J, Zeid R, Schumacher SE, Urbanski L, O'Rourke R, Gibson WJ, Pelton K, Ramkissoon SH, Han HJ, Zhu Y, Choudhari N, Silva A, Boucher K, Henn RE, Kang YJ, Knoff D, Paolella BR, Gladden-Young A, Varlet P, Pages M, Horowitz PM, Federation A, Malkin H, Tracy AA, Seepo S, Ducar M, Van Hummelen P, Santi M, Buccoliero AM, Scagnet M, Bowers DC, Giannini C, Puget S, Hawkins C, Tabori U, Klekner A, Bognar L, Burger PC, Eberhart C, Rodriguez FJ, Hill DA, Mueller S, Haas-Kogan DA, Phillips JJ, Santagata S, Stiles CD, Bradner JE, Jabado N, Goren A, Grill J, Ligon AH, Goumnerova L, Waanders AJ, Storm PB, Kieran MW, Ligon KL, Beroukhim R, Resnick AC.

Nat Genet. 2016 Mar;48(3):273-82. doi: 10.1038/ng.3500. Epub 2016 Feb 1.

39.

Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma.

Abedalthagafi M, Bi WL, Aizer AA, Merrill PH, Brewster R, Agarwalla PK, Listewnik ML, Dias-Santagata D, Thorner AR, Van Hummelen P, Brastianos PK, Reardon DA, Wen PY, Al-Mefty O, Ramkissoon SH, Folkerth RD, Ligon KL, Ligon AH, Alexander BM, Dunn IF, Beroukhim R, Santagata S.

Neuro Oncol. 2016 May;18(5):649-55. doi: 10.1093/neuonc/nov316. Epub 2016 Jan 28.

40.

Genomic landscape of intracranial meningiomas.

Bi WL, Abedalthagafi M, Horowitz P, Agarwalla PK, Mei Y, Aizer AA, Brewster R, Dunn GP, Al-Mefty O, Alexander BM, Santagata S, Beroukhim R, Dunn IF.

J Neurosurg. 2016 Sep;125(3):525-35. doi: 10.3171/2015.6.JNS15591. Epub 2016 Jan 15.

PMID:
26771848
41.

Decreased FOXJ1 expression and its ciliogenesis programme in aggressive ependymoma and choroid plexus tumours.

Abedalthagafi MS, Wu MP, Merrill PH, Du Z, Woo T, Sheu SH, Hurwitz S, Ligon KL, Santagata S.

J Pathol. 2016 Mar;238(4):584-97. doi: 10.1002/path.4682.

42.

ENDOCRINE TUMORS: BRAF V600E mutations in papillary craniopharyngioma.

Brastianos PK, Santagata S.

Eur J Endocrinol. 2016 Apr;174(4):R139-44. doi: 10.1530/EJE-15-0957. Epub 2015 Nov 12. Review.

43.

Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy.

Brastianos PK, Shankar GM, Gill CM, Taylor-Weiner A, Nayyar N, Panka DJ, Sullivan RJ, Frederick DT, Abedalthagafi M, Jones PS, Dunn IF, Nahed BV, Romero JM, Louis DN, Getz G, Cahill DP, Santagata S, Curry WT Jr, Barker FG 2nd.

J Natl Cancer Inst. 2015 Oct 23;108(2). pii: djv310. doi: 10.1093/jnci/djv310. Print 2016 Feb.

44.

Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets.

Brastianos PK, Carter SL, Santagata S, Cahill DP, Taylor-Weiner A, Jones RT, Van Allen EM, Lawrence MS, Horowitz PM, Cibulskis K, Ligon KL, Tabernero J, Seoane J, Martinez-Saez E, Curry WT, Dunn IF, Paek SH, Park SH, McKenna A, Chevalier A, Rosenberg M, Barker FG 2nd, Gill CM, Van Hummelen P, Thorner AR, Johnson BE, Hoang MP, Choueiri TK, Signoretti S, Sougnez C, Rabin MS, Lin NU, Winer EP, Stemmer-Rachamimov A, Meyerson M, Garraway L, Gabriel S, Lander ES, Beroukhim R, Batchelor TT, Baselga J, Louis DN, Getz G, Hahn WC.

Cancer Discov. 2015 Nov;5(11):1164-1177. doi: 10.1158/2159-8290.CD-15-0369. Epub 2015 Sep 26.

45.

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome.

Tsvetkov P, Mendillo ML, Zhao J, Carette JE, Merrill PH, Cikes D, Varadarajan M, van Diemen FR, Penninger JM, Goldberg AL, Brummelkamp TR, Santagata S, Lindquist S.

Elife. 2015 Sep 1;4. doi: 10.7554/eLife.08467.

46.

A prognostic cytogenetic scoring system to guide the adjuvant management of patients with atypical meningioma.

Aizer AA, Abedalthagafi M, Bi WL, Horvath MC, Arvold ND, Al-Mefty O, Lee EQ, Nayak L, Rinne ML, Norden AD, Reardon DA, Wen PY, Ligon KL, Ligon AH, Beroukhim R, Dunn IF, Santagata S, Alexander BM.

Neuro Oncol. 2016 Feb;18(2):269-74. doi: 10.1093/neuonc/nov177. Epub 2015 Aug 30.

47.

MALDI mass spectrometry imaging analysis of pituitary adenomas for near-real-time tumor delineation.

Calligaris D, Feldman DR, Norton I, Olubiyi O, Changelian AN, Machaidze R, Vestal ML, Laws ER, Dunn IF, Santagata S, Agar NY.

Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9978-83. doi: 10.1073/pnas.1423101112. Epub 2015 Jul 27.

48.

Urine sepiapterin excretion as a new diagnostic marker for sepiapterin reductase deficiency.

Carducci C, Santagata S, Friedman J, Pasquini E, Carducci C, Tolve M, Angeloni A, Leuzzi V.

Mol Genet Metab. 2015 Aug;115(4):157-60. doi: 10.1016/j.ymgme.2015.06.009. Epub 2015 Jun 25.

PMID:
26123188
49.

Profiling of adrenocorticotropic hormone and arginine vasopressin in human pituitary gland and tumor thin tissue sections using droplet-based liquid-microjunction surface-sampling-HPLC-ESI-MS-MS.

Kertesz V, Calligaris D, Feldman DR, Changelian A, Laws ER, Santagata S, Agar NY, Van Berkel GJ.

Anal Bioanal Chem. 2015 Aug;407(20):5989-98. doi: 10.1007/s00216-015-8803-2. Epub 2015 Jun 18.

50.

ARID1A and TERT promoter mutations in dedifferentiated meningioma.

Abedalthagafi MS, Bi WL, Merrill PH, Gibson WJ, Rose MF, Du Z, Francis JM, Du R, Dunn IF, Ligon AH, Beroukhim R, Santagata S.

Cancer Genet. 2015 Jun;208(6):345-50. doi: 10.1016/j.cancergen.2015.03.005. Epub 2015 Mar 18.

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