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Items: 12


Tuning the specificity of a Two-in-One Fab against three angiogenic antigens by fully utilizing the information of deep mutational scanning.

Koenig P, Sanowar S, Lee CV, Fuh G.

MAbs. 2017 Aug/Sep;9(6):959-967. doi: 10.1080/19420862.2017.1337618. Epub 2017 Jun 6.


Design and Pharmacokinetic Characterization of Novel Antibody Formats for Ocular Therapeutics.

Gadkar K, Pastuskovas CV, Le Couter JE, Elliott JM, Zhang J, Lee CV, Sanowar S, Fuh G, Kim HS, Lombana TN, Spiess C, Nakamura M, Hass P, Shatz W, Meng YG, Scheer JM.

Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5390-400. doi: 10.1167/iovs.15-17108.


Deep Sequencing-guided Design of a High Affinity Dual Specificity Antibody to Target Two Angiogenic Factors in Neovascular Age-related Macular Degeneration.

Koenig P, Lee CV, Sanowar S, Wu P, Stinson J, Harris SF, Fuh G.

J Biol Chem. 2015 Sep 4;290(36):21773-86. doi: 10.1074/jbc.M115.662783. Epub 2015 Jun 18.


The type III secretion system as a source of novel antibacterial drug targets.

Kline T, Felise HB, Sanowar S, Miller SI.

Curr Drug Targets. 2012 Mar;13(3):338-51. Review.


Interactions of the transmembrane polymeric rings of the Salmonella enterica serovar Typhimurium type III secretion system.

Sanowar S, Singh P, Pfuetzner RA, André I, Zheng H, Spreter T, Strynadka NC, Gonen T, Baker D, Goodlett DR, Miller SI.

MBio. 2010 Aug 3;1(3). pii: e00158-10. doi: 10.1128/mBio.00158-10.


Antimicrobial peptides activate the Rcs regulon through the outer membrane lipoprotein RcsF.

Farris C, Sanowar S, Bader MW, Pfuetzner R, Miller SI.

J Bacteriol. 2010 Oct;192(19):4894-903. doi: 10.1128/JB.00505-10. Epub 2010 Jul 30.


A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system.

Spreter T, Yip CK, Sanowar S, André I, Kimbrough TG, Vuckovic M, Pfuetzner RA, Deng W, Yu AC, Finlay BB, Baker D, Miller SI, Strynadka NC.

Nat Struct Mol Biol. 2009 May;16(5):468-76. doi: 10.1038/nsmb.1603. Epub 2009 Apr 26.


Did bacterial sensing of host environments evolve from sensing within microbial communities?

Miller SI, Hoffman LR, Sanowar S.

Cell Host Microbe. 2007 Apr 19;1(2):85-7.


Salmonella sensing of anti-microbial mechanisms to promote survival within macrophages.

Prost LR, Sanowar S, Miller SI.

Immunol Rev. 2007 Oct;219:55-65. Review.


Recognition of antimicrobial peptides by a bacterial sensor kinase.

Bader MW, Sanowar S, Daley ME, Schneider AR, Cho U, Xu W, Klevit RE, Le Moual H, Miller SI.

Cell. 2005 Aug 12;122(3):461-72.


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