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Comparison of oncological outcomes after open and laparoscopic re-resection of incidental gallbladder cancer.

Vega EA, De Aretxabala X, Qiao W, Newhook TE, Okuno M, Castillo F, Sanhueza M, Diaz C, Cavada G, Jarufe N, Munoz C, Rencoret G, Vivanco M, Joechle K, Tzeng CD, Vauthey JN, Vinuela E, Conrad C.

Br J Surg. 2020 Feb;107(3):289-300. doi: 10.1002/bjs.11379. Epub 2019 Dec 24.


Modulation of Frequency Preference in Heterogeneous Populations of Theta-resonant Neurons.

Vera J, Pereira U, Reynaert B, Bacigalupo J, Sanhueza M.

Neuroscience. 2020 Feb 1;426:13-32. doi: 10.1016/j.neuroscience.2019.10.054. Epub 2019 Nov 27.


Effects of three biochars on copper immobilization and soil microbial communities in a metal-contaminated soil using a metallophyte and two agricultural plants.

Meier S, Moore F, González ME, Medina J, Campos P, Khan N, Cumming J, Sanhueza M, Mejías J, Morales A, Hirzel J, Seguel A.

Environ Geochem Health. 2019 Oct 10. doi: 10.1007/s10653-019-00436-x. [Epub ahead of print]


Minimally Invasive Surgery for Gallbladder Cancer.

Vega EA, Sanhueza M, Viñuela E.

Surg Oncol Clin N Am. 2019 Apr;28(2):243-253. doi: 10.1016/j.soc.2018.11.001. Epub 2019 Feb 2. Review.


Incidental versus non-incidental gallbladder cancer: index cholecystectomy before oncologic re-resection negatively impacts survival in T2b tumors.

Vega EA, Vinuela E, Okuno M, Joechle K, Sanhueza M, Diaz C, Jarufe N, Martinez J, Troncoso A, Diaz A, Chun YS, Tzeng CD, Lee JE, Vauthey JN, Conrad C.

HPB (Oxford). 2019 Aug;21(8):1046-1056. doi: 10.1016/j.hpb.2018.12.006. Epub 2019 Jan 31.


Positive cystic duct margin at index cholecystectomy in incidental gallbladder cancer is an important negative prognosticator.

Vega EA, Vinuela E, Sanhueza M, Mege R, Caracci M, Diaz C, Diaz A, Okuno M, Joechle K, Goumard C, Chun YS, Tzeng CD, Lee JE, Vauthey JN, Conrad C.

Eur J Surg Oncol. 2019 Jun;45(6):1061-1068. doi: 10.1016/j.ejso.2019.01.013. Epub 2019 Jan 24.


Changes in the content of anthocyanins, flavonols, and antioxidant activity in Fragaria ananassa var. Camarosa fruits under traditional and organic fertilization.

Ruiz A, Sanhueza M, Gómez F, Tereucán G, Valenzuela T, García S, Cornejo P, Hermosín-Gutiérrez I.

J Sci Food Agric. 2019 Mar 30;99(5):2404-2410. doi: 10.1002/jsfa.9447. Epub 2018 Dec 9.


Mitochondria and Calcium Regulation as Basis of Neurodegeneration Associated With Aging.

Müller M, Ahumada-Castro U, Sanhueza M, Gonzalez-Billault C, Court FA, Cárdenas C.

Front Neurosci. 2018 Jul 13;12:470. doi: 10.3389/fnins.2018.00470. eCollection 2018.


Allopregnanolone alters follicular and luteal dynamics during the estrous cycle.

Asensio JA, Cáceres ARR, Pelegrina LT, Sanhueza MLÁ, Scotti L, Parborell F, Laconi MR.

Reprod Biol Endocrinol. 2018 Apr 10;16(1):35. doi: 10.1186/s12958-018-0353-y.


[Tako-tsubo syndrome. Analysis of 37 cases].

Ugalde H, Yubini MC, Sanhueza MI, Ayala F, Chaigneau E, Dussaillant G, García S, Farías E, Villagra K, Inostroza P.

Rev Med Chil. 2017 Oct;145(10):1268-1275. doi: 10.4067/S0034-98872017001001268. Spanish. No abstract available.


Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative Disorders.

Salvadores N, Sanhueza M, Manque P, Court FA.

Front Neurosci. 2017 Sep 4;11:451. doi: 10.3389/fnins.2017.00451. eCollection 2017. Review.


[Prediction of hospital mortality of ST elevation myocardial infarction using TIMI score].

Ugalde H, Yubini MC, Rozas S, Sanhueza MI, Jara H.

Rev Med Chil. 2017 May;145(5):572-578. doi: 10.4067/S0034-98872017000500003. Spanish.


Extended Lymphadenectomy Is Required for Incidental Gallbladder Cancer Independent of Cystic Duct Lymph Node Status.

Vega EA, Vinuela E, Yamashita S, Sanhueza M, Cavada G, Diaz C, Aloia TA, Chun YS, Tzeng CD, Okuno M, Goumard C, Vauthey JN, Lee JE, Conrad C.

J Gastrointest Surg. 2018 Jan;22(1):43-51. doi: 10.1007/s11605-017-3507-x. Epub 2017 Jul 27.


Human Peritoneal Mesothelial Cell Death Induced by High-Glucose Hypertonic Solution Involves Ca2+ and Na+ Ions and Oxidative Stress with the Participation of PKC/NOX2 and PI3K/Akt Pathways.

Simon F, Tapia P, Armisen R, Echeverria C, Gatica S, Vallejos A, Pacheco A, Sanhueza ME, Alvo M, Segovia E, Torres R.

Front Physiol. 2017 Jun 13;8:379. doi: 10.3389/fphys.2017.00379. eCollection 2017.


Incidental Gallbladder Cancer: Residual Cancer Discovered at Oncologic Extended Resection Determines Outcome: A Report from High- and Low-Incidence Countries.

Vinuela E, Vega EA, Yamashita S, Sanhueza M, Mege R, Cavada G, Aloia TA, Chun YS, Lee JE, Vauthey JN, Conrad C.

Ann Surg Oncol. 2017 Aug;24(8):2334-2343. doi: 10.1245/s10434-017-5859-6. Epub 2017 Apr 17.


[Encapsulating peritoneal sclerosis].

Torres R, Ebner P, Sanhueza ME, Alvo M, Segovia E, Segura P.

Rev Med Chil. 2017 Jan;145(1):41-48. doi: 10.4067/S0034-98872017000100006. Spanish.


[Comparative evaluation of survival prognosis using MELD or Child-Pugh scores in patients with liver cirrhosis in Chile].

Sanhueza E, Contreras J, Zapata R, Sanhueza M, Elgueta F, López C, Jerez S, Jerez V, Delgado I.

Rev Med Chil. 2017 Jan;145(1):17-24. doi: 10.4067/S0034-98872017000100003. Spanish.


Competition between Persistent Na+ and Muscarine-Sensitive K+ Currents Shapes Perithreshold Resonance and Spike Tuning in CA1 Pyramidal Neurons.

Vera J, Alcayaga J, Sanhueza M.

Front Cell Neurosci. 2017 Mar 8;11:61. doi: 10.3389/fncel.2017.00061. eCollection 2017.


NMDA receptor subunit composition controls dendritogenesis of hippocampal neurons through CAMKII, CREB-P, and H3K27ac.

Bustos FJ, Jury N, Martinez P, Ampuero E, Campos M, Abarzúa S, Jaramillo K, Ibing S, Mardones MD, Haensgen H, Kzhyshkowska J, Tevy MF, Neve R, Sanhueza M, Varela-Nallar L, Montecino M, van Zundert B.

J Cell Physiol. 2017 Dec;232(12):3677-3692. doi: 10.1002/jcp.25843. Epub 2017 May 11.


[Normoglycemic diabetic ketoacidosis in pregnancy: Report of one case].

Rivas M M, Belmar Z P, Durruty A P, Sanhueza M L, López S G.

Rev Med Chil. 2016 Oct;144(10):1360-1364. doi: 10.4067/S0034-98872016001000018. Spanish.


An unusual case of tubulointerstitial renal mastocytosis.

Sanhueza ME, Segura P, Murray G, Torres R, Toro L.

Kidney Int. 2017 Jan;91(1):256. doi: 10.1016/j.kint.2016.08.012. No abstract available.


Why Quantification Matters: Characterization of Phenotypes at the Drosophila Larval Neuromuscular Junction.

Sanhueza M, Kubasik-Thayil A, Pennetta G.

J Vis Exp. 2016 May 12;(111). doi: 10.3791/53821.


The Fortress Becomes a Prison: Calcified Constrictive Pericarditis.

Sanhueza ME, Torres R, Segura P, Villalobos A, Segovia E.

Am J Med. 2016 Mar;129(3):263-5. doi: 10.1016/j.amjmed.2015.10.006. Epub 2015 Oct 29. No abstract available.


Network analyses reveal novel aspects of ALS pathogenesis.

Sanhueza M, Chai A, Smith C, McCray BA, Simpson TI, Taylor JP, Pennetta G.

PLoS Genet. 2015 Mar 31;11(3):e1005107. doi: 10.1371/journal.pgen.1005107. eCollection 2015 Mar.


[Emphysematous cystitis: report of one case].

Oñate EP, Sanhueza ME, Torres R, Segovia E.

Rev Med Chil. 2014 Jan;142(1):114-7. doi: 10.4067/S0034-98872014000100018. Spanish.


Outbreak of Paecilomyces variotii peritonitis in peritoneal dialysis patients after the 2010 Chilean earthquake.

Torres R, Gonzalez M, Sanhueza M, Segovia E, Alvo M, Passalacqua W, Saffie A, Elgueta L, Diaz M, Silva F.

Perit Dial Int. 2014 May;34(3):322-5. doi: 10.3747/pdi.2013.00157. Epub 2014 Mar 1. No abstract available.


Electrical resonance in the θ frequency range in olfactory amygdala neurons.

Vera J, Pezzoli M, Pereira U, Bacigalupo J, Sanhueza M.

PLoS One. 2014 Jan 21;9(1):e85826. doi: 10.1371/journal.pone.0085826. eCollection 2014.


Gain-of-function mutations in the ALS8 causative gene VAPB have detrimental effects on neurons and muscles.

Sanhueza M, Zechini L, Gillespie T, Pennetta G.

Biol Open. 2014 Jan 15;3(1):59-71. doi: 10.1242/bio.20137070.


Increased levels of phosphoinositides cause neurodegeneration in a Drosophila model of amyotrophic lateral sclerosis.

Forrest S, Chai A, Sanhueza M, Marescotti M, Parry K, Georgiev A, Sahota V, Mendez-Castro R, Pennetta G.

Hum Mol Genet. 2013 Jul 1;22(13):2689-704. doi: 10.1093/hmg/ddt118. Epub 2013 Mar 13.


The CaMKII/NMDAR complex as a molecular memory.

Sanhueza M, Lisman J.

Mol Brain. 2013 Feb 14;6:10. doi: 10.1186/1756-6606-6-10. Review.


A genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's disease.

Miller JP, Yates BE, Al-Ramahi I, Berman AE, Sanhueza M, Kim E, de Haro M, DeGiacomo F, Torcassi C, Holcomb J, Gafni J, Mooney SD, Botas J, Ellerby LM, Hughes RE.

PLoS Genet. 2012;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29.


On the mechanism of synaptic depression induced by CaMKIIN, an endogenous inhibitor of CaMKII.

Gouet C, Aburto B, Vergara C, Sanhueza M.

PLoS One. 2012;7(11):e49293. doi: 10.1371/journal.pone.0049293. Epub 2012 Nov 8.


TRP, TRPL and cacophony channels mediate Ca2+ influx and exocytosis in photoreceptors axons in Drosophila.

Astorga G, Härtel S, Sanhueza M, Bacigalupo J.

PLoS One. 2012;7(8):e44182. doi: 10.1371/journal.pone.0044182. Epub 2012 Aug 31.


Molecular characterization of totiviruses in Xanthophyllomyces dendrorhous.

Baeza M, Bravo N, Sanhueza M, Flores O, Villarreal P, Cifuentes V.

Virol J. 2012 Jul 28;9:140. doi: 10.1186/1743-422X-9-140.


[Results of pancreaticoduodenectomy in the treatment of periampullary tumors].

Norero E, Viñuela E, Báez S, Martínez C, Reyes J, Kusanovic R, Sanhueza M, Aguayo G, Calvo A, Mege RM, Caracci M, Díaz A.

Rev Med Chil. 2011 Aug;139(8):1015-24. doi: /S0034-98872011000800006. Epub 2011 Dec 20. Spanish.


Role of the CaMKII/NMDA receptor complex in the maintenance of synaptic strength.

Sanhueza M, Fernandez-Villalobos G, Stein IS, Kasumova G, Zhang P, Bayer KU, Otmakhov N, Hell JW, Lisman J.

J Neurosci. 2011 Jun 22;31(25):9170-8. doi: 10.1523/JNEUROSCI.1250-11.2011.


[Body composition assessment in patients with chronic renal failure].

Cano M, Camousseigt J, Carrasco F, Rojas P, Inostroza J, Pardo A, Faundez V, Loncon P, Pacheco A, Sanhueza ME.

Nutr Hosp. 2010 Jul-Aug;25(4):682-7. Spanish.


Matrix metalloproteinases are modifiers of huntingtin proteolysis and toxicity in Huntington's disease.

Miller JP, Holcomb J, Al-Ramahi I, de Haro M, Gafni J, Zhang N, Kim E, Sanhueza M, Torcassi C, Kwak S, Botas J, Hughes RE, Ellerby LM.

Neuron. 2010 Jul 29;67(2):199-212. doi: 10.1016/j.neuron.2010.06.021.


Study of Chilean children's dental maturation.

Flores AP, Sanhueza MA, Barboza P, Monti CF.

J Forensic Sci. 2010 May;55(3):735-7. doi: 10.1111/j.1556-4029.2009.01274.x. Epub 2010 Jan 19.


Polymorphism of viral dsRNA in Xanthophyllomyces dendrorhous strains isolated from different geographic areas.

Baeza M, Sanhueza M, Flores O, Oviedo V, Libkind D, Cifuentes V.

Virol J. 2009 Oct 8;6:160. doi: 10.1186/1743-422X-6-160.


Occurrence of killer yeast strains in industrial and clinical yeast isolates.

Baeza ME, Sanhueza MA, Cifuentes VH.

Biol Res. 2008;41(2):173-82. doi: /S0716-97602008000200007. Epub 2008 Oct 8.


[Assessment and follow up of diabetic patients in hemodialysis].

Sanhueza ME, Cotera A, Elgueta L, López S G, Loncon P, Macan F, Pérez F, Cavada G, Alvo M.

Rev Med Chil. 2008 Mar;136(3):279-86. doi: /S0034-98872008000300001. Epub 2008 Jun 3. Spanish.


[Study of aerobic capacity in chronic hemodialized patients: effect of L-carnitine supplementation].

Pacheco A, Torres R, Sanhueza ME, Elgueta L, Segovia E, Cano M.

Med Clin (Barc). 2008 Apr 5;130(12):441-5. Spanish.


Resection of hepatocellular carcinoma: the effect of surgical margin and blood transfusion on long-term survival. Analysis of 209 consecutive patients.

Tralhão JG, Kayal S, Dagher I, Sanhueza M, Vons C, Franco D.

Hepatogastroenterology. 2007 Jun;54(76):1200-6.


Reversal of synaptic memory by Ca2+/calmodulin-dependent protein kinase II inhibitor.

Sanhueza M, McIntyre CC, Lisman JE.

J Neurosci. 2007 May 9;27(19):5190-9.


[Appendectomies for suspected acute appendicitis during pregnancy: experience at a Chilean public hospital].

Butte JM, Bellolio MF, Fernández F, Sanhueza M, Báez S, Kusanovich R, Viñuela E, González R, Pruyas M, Díaz V, Martínez J.

Rev Med Chil. 2006 Feb;134(2):145-51. Epub 2006 Mar 17. Spanish.


[Outpatient laparoscopic cholecystectomy. Experience in 357 patients].

Pattillo JC, Kusanovic R, Salas P, Reyes J, García-Huidobro I, Sanhueza M, Palma A, Báez S, Viñuela E, Friant O, Galaz I, Silberman M, Arrese M, Martínez J.

Rev Med Chil. 2004 Apr;132(4):429-36. Spanish.


[Albumin dialysis MARS (Molecular Adsorbent Recirculating System) as a bridge for liver transplantation in acute liver failure. Report of three cases].

Contreras J, Poniachik J, Oksenberg D, Cortés C, Valera JM, Cotera A, Pacheco A, Segovia E, Sanhueza ME, Boltansky A, Rojas J, Guerrero J, Díaz JC.

Rev Med Chil. 2004 May;132(5):601-7. Spanish.


Tonic and phasic receptor neurons in the vertebrate olfactory epithelium.

Madrid R, Sanhueza M, Alvarez O, Bacigalupo J.

Biophys J. 2003 Jun;84(6):4167-81.

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