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Items: 1 to 50 of 186

1.

Link between Heat Shock Protein 90 and the Mitochondrial Respiratory Chain in the Caspofungin Stress Response of Aspergillus fumigatus.

Aruanno M, Bachmann D, Sanglard D, Lamoth F.

Antimicrob Agents Chemother. 2019 Jun 24;63(7). pii: e00208-19. doi: 10.1128/AAC.00208-19. Print 2019 Jul.

PMID:
31061164
2.

Persistence of Candida albicans in the Oral Mucosa Induces a Curbed Inflammatory Host Response That Is Independent of Immunosuppression.

Kirchner FR, Littringer K, Altmeier S, Tran VDT, Schönherr F, Lemberg C, Pagni M, Sanglard D, Joller N, LeibundGut-Landmann S.

Front Immunol. 2019 Feb 27;10:330. doi: 10.3389/fimmu.2019.00330. eCollection 2019.

3.

Finding the needle in a haystack: Mapping antifungal drug resistance in fungal pathogen by genomic approaches.

Sanglard D.

PLoS Pathog. 2019 Jan 31;15(1):e1007478. doi: 10.1371/journal.ppat.1007478. eCollection 2019 Jan. Review. No abstract available.

4.

Condition-specific series of metabolic sub-networks and its application for gene set enrichment analysis.

Tran VDT, Moretti S, Coste AT, Amorim-Vaz S, Sanglard D, Pagni M.

Bioinformatics. 2018 Nov 16. doi: 10.1093/bioinformatics/bty929. [Epub ahead of print]

5.

Implications of the EUCAST Trailing Phenomenon in Candida tropicalis for the In Vivo Susceptibility in Invertebrate and Murine Models.

Astvad KMT, Sanglard D, Delarze E, Hare RK, Arendrup MC.

Antimicrob Agents Chemother. 2018 Nov 26;62(12). pii: e01624-18. doi: 10.1128/AAC.01624-18. Print 2018 Dec.

6.

Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms.

Van Dijck P, Sjollema J, Cammue BP, Lagrou K, Berman J, d'Enfert C, Andes DR, Arendrup MC, Brakhage AA, Calderone R, Cantón E, Coenye T, Cos P, Cowen LE, Edgerton M, Espinel-Ingroff A, Filler SG, Ghannoum M, Gow NAR, Haas H, Jabra-Rizk MA, Johnson EM, Lockhart SR, Lopez-Ribot JL, Maertens J, Munro CA, Nett JE, Nobile CJ, Pfaller MA, Ramage G, Sanglard D, Sanguinetti M, Spriet I, Verweij PE, Warris A, Wauters J, Yeaman MR, Zaat SAJ, Thevissen K.

Microb Cell. 2018 Jun 14;5(7):300-326. doi: 10.15698/mic2018.07.638. Review.

7.

Accuracy of Sensititre YeastOne echinocandins epidemiological cut-off values for identification of FKS mutant Candida albicans and Candida glabrata: a ten year national survey of the Fungal Infection Network of Switzerland (FUNGINOS).

Kritikos A, Neofytos D, Khanna N, Schreiber PW, Boggian K, Bille J, Schrenzel J, Mühlethaler K, Zbinden R, Bruderer T, Goldenberger D, Pfyffer G, Conen A, Van Delden C, Zimmerli S, Sanglard D, Bachmann D, Marchetti O, Lamoth F; Fungal Infection Network of Switzerland (FUNGINOS).

Clin Microbiol Infect. 2018 Nov;24(11):1214.e1-1214.e4. doi: 10.1016/j.cmi.2018.05.012. Epub 2018 Jun 15.

PMID:
29909005
8.

Worldwide emergence of resistance to antifungal drugs challenges human health and food security.

Fisher MC, Hawkins NJ, Sanglard D, Gurr SJ.

Science. 2018 May 18;360(6390):739-742. doi: 10.1126/science.aap7999. Review.

9.

Azole Resistance of Environmental and Clinical Aspergillus fumigatus Isolates from Switzerland.

Riat A, Plojoux J, Gindro K, Schrenzel J, Sanglard D.

Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e02088-17. doi: 10.1128/AAC.02088-17. Print 2018 Apr.

10.

Azole resistance in a Candida albicans mutant lacking the ABC transporter CDR6/ROA1 depends on TOR signaling.

Khandelwal NK, Chauhan N, Sarkar P, Esquivel BD, Coccetti P, Singh A, Coste AT, Gupta M, Sanglard D, White TC, Chauvel M, d'Enfert C, Chattopadhyay A, Gaur NA, Mondal AK, Prasad R.

J Biol Chem. 2018 Jan 12;293(2):412-432. doi: 10.1074/jbc.M117.807032. Epub 2017 Nov 20.

11.

A standardized toolkit for genetic engineering of CTG clade yeasts.

Defosse TA, Courdavault V, Coste AT, Clastre M, de Bernonville TD, Godon C, Vandeputte P, Lanoue A, Touzé A, Linder T, Droby S, Rosa CA, Sanglard D, d'Enfert C, Bouchara JP, Giglioli-Guivarc'h N, Papon N.

J Microbiol Methods. 2018 Jan;144:152-156. doi: 10.1016/j.mimet.2017.11.015. Epub 2017 Nov 16.

PMID:
29155237
12.

Potential Use of MALDI-ToF Mass Spectrometry for Rapid Detection of Antifungal Resistance in the Human Pathogen Candida glabrata.

Vella A, De Carolis E, Mello E, Perlin DS, Sanglard D, Sanguinetti M, Posteraro B.

Sci Rep. 2017 Aug 22;7(1):9099. doi: 10.1038/s41598-017-09329-4.

13.

Red-Shifted Firefly Luciferase Optimized for Candida albicans In vivo Bioluminescence Imaging.

Dorsaz S, Coste AT, Sanglard D.

Front Microbiol. 2017 Aug 3;8:1478. doi: 10.3389/fmicb.2017.01478. eCollection 2017.

14.

Identification and Mode of Action of a Plant Natural Product Targeting Human Fungal Pathogens.

Dorsaz S, Snäkä T, Favre-Godal Q, Maudens P, Boulens N, Furrer P, Ebrahimi SN, Hamburger M, Allémann E, Gindro K, Queiroz EF, Riezman H, Wolfender JL, Sanglard D.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00829-17. doi: 10.1128/AAC.00829-17. Print 2017 Sep.

15.

Phenotypic and genotypic characterization of Staphylococcus aureus isolates in milk from flocks diagnosed with subclinical mastitis.

Xavier AREO, Almeida AC, Souza CN, Silva LMV, Ruas AXA, Sanglard DA, Júnior AFM, Oliveira AME, Xavier MAS.

Genet Mol Res. 2017 Jun 29;16(2). doi: 10.4238/gmr16029709.

PMID:
28671260
16.

Comparative Genomics of Two Sequential Candida glabrata Clinical Isolates.

Vale-Silva L, Beaudoing E, Tran VDT, Sanglard D.

G3 (Bethesda). 2017 Aug 7;7(8):2413-2426. doi: 10.1534/g3.117.042887.

17.

The Swiss Society of Microbiology: Small Bugs, Big Questions and Cool Answers.

Greub G, Holliger C, Sanglard D, Schrenzel J, Thiel V, Viollier P.

Chimia (Aarau). 2016 Dec 21;70(12):874-877. doi: 10.2533/chimia.2016.874.

18.

High-Resolution Genetics Identifies the Lipid Transfer Protein Sec14p as Target for Antifungal Ergolines.

Filipuzzi I, Cotesta S, Perruccio F, Knapp B, Fu Y, Studer C, Pries V, Riedl R, Helliwell SB, Petrovic KT, Movva NR, Sanglard D, Tao J, Hoepfner D.

PLoS Genet. 2016 Nov 17;12(11):e1006374. doi: 10.1371/journal.pgen.1006374. eCollection 2016 Nov.

19.

Dual action antifungal small molecule modulates multidrug efflux and TOR signaling.

Shekhar-Guturja T, Gunaherath GM, Wijeratne EM, Lambert JP, Averette AF, Lee SC, Kim T, Bahn YS, Tripodi F, Ammar R, Döhl K, Niewola-Staszkowska K, Schmitt L, Loewith RJ, Roth FP, Sanglard D, Andes D, Nislow C, Coccetti P, Gingras AC, Heitman J, Gunatilaka AA, Cowen LE.

Nat Chem Biol. 2016 Oct;12(10):867-75. doi: 10.1038/nchembio.2165. Epub 2016 Aug 29.

20.

Upregulation of the Adhesin Gene EPA1 Mediated by PDR1 in Candida glabrata Leads to Enhanced Host Colonization.

Vale-Silva LA, Moeckli B, Torelli R, Posteraro B, Sanguinetti M, Sanglard D.

mSphere. 2016 Mar 2;1(2). pii: e00065-15. doi: 10.1128/mSphere.00065-15. eCollection 2016 Mar-Apr.

21.

Biological Characterization and in Vivo Assessment of the Activity of a New Synthetic Macrocyclic Antifungal Compound.

Deodato D, Maccari G, De Luca F, Sanfilippo S, Casian A, Martini R, D'Arezzo S, Bonchi C, Bugli F, Posteraro B, Vandeputte P, Sanglard D, Docquier JD, Sanguinetti M, Visca P, Botta M.

J Med Chem. 2016 Apr 28;59(8):3854-66. doi: 10.1021/acs.jmedchem.6b00018. Epub 2016 Apr 19.

PMID:
27045868
22.

Pleiotropic effects of the vacuolar ABC transporter MLT1 of Candida albicans on cell function and virulence.

Khandelwal NK, Kaemmer P, Förster TM, Singh A, Coste AT, Andes DR, Hube B, Sanglard D, Chauhan N, Kaur R, d'Enfert C, Mondal AK, Prasad R.

Biochem J. 2016 Jun 1;473(11):1537-52. doi: 10.1042/BCJ20160024. Epub 2016 Mar 29.

23.

Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance.

Healey KR, Zhao Y, Perez WB, Lockhart SR, Sobel JD, Farmakiotis D, Kontoyiannis DP, Sanglard D, Taj-Aldeen SJ, Alexander BD, Jimenez-Ortigosa C, Shor E, Perlin DS.

Nat Commun. 2016 Mar 29;7:11128. doi: 10.1038/ncomms11128.

24.

Emerging Threats in Antifungal-Resistant Fungal Pathogens.

Sanglard D.

Front Med (Lausanne). 2016 Mar 15;3:11. doi: 10.3389/fmed.2016.00011. eCollection 2016. Review.

25.

A New Endogenous Overexpression System of Multidrug Transporters of Candida albicans Suitable for Structural and Functional Studies.

Banerjee A, Khandelwal NK, Sanglard D, Prasad R.

Front Microbiol. 2016 Mar 3;7:261. doi: 10.3389/fmicb.2016.00261. eCollection 2016.

26.

Identification of Aspergillus fumigatus multidrug transporter genes and their potential involvement in antifungal resistance.

Meneau I, Coste AT, Sanglard D.

Med Mycol. 2016 Aug 1;54(6):616-27. doi: 10.1093/mmy/myw005. Epub 2016 Mar 1.

PMID:
26933209
27.

Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction.

Nishikawa JL, Boeszoermenyi A, Vale-Silva LA, Torelli R, Posteraro B, Sohn YJ, Ji F, Gelev V, Sanglard D, Sanguinetti M, Sadreyev RI, Mukherjee G, Bhyravabhotla J, Buhrlage SJ, Gray NS, Wagner G, Näär AM, Arthanari H.

Nature. 2016 Feb 25;530(7591):485-9. doi: 10.1038/nature16963. Epub 2016 Feb 17.

28.

Antifungal Quinoline Alkaloids from Waltheria indica.

Cretton S, Dorsaz S, Azzollini A, Favre-Godal Q, Marcourt L, Ebrahimi SN, Voinesco F, Michellod E, Sanglard D, Gindro K, Wolfender JL, Cuendet M, Christen P.

J Nat Prod. 2016 Feb 26;79(2):300-7. doi: 10.1021/acs.jnatprod.5b00896. Epub 2016 Feb 5.

PMID:
26848627
29.

Novel Approaches for Fungal Transcriptomics from Host Samples.

Amorim-Vaz S, Sanglard D.

Front Microbiol. 2016 Jan 19;6:1571. doi: 10.3389/fmicb.2015.01571. eCollection 2015. Review.

30.

Defining the frontiers between antifungal resistance, tolerance and the concept of persistence.

Delarze E, Sanglard D.

Drug Resist Updat. 2015 Nov;23:12-19. doi: 10.1016/j.drup.2015.10.001. Epub 2015 Oct 30. Review.

PMID:
26690338
31.

Anti-Candida Cassane-Type Diterpenoids from the Root Bark of Swartzia simplex.

Favre-Godal Q, Dorsaz S, Queiroz EF, Marcourt L, Ebrahimi SN, Allard PM, Voinesco F, Hamburger M, Gupta MP, Gindro K, Sanglard D, Wolfender JL.

J Nat Prod. 2015 Dec 24;78(12):2994-3004. doi: 10.1021/acs.jnatprod.5b00744. Epub 2015 Dec 11.

PMID:
26654828
32.

Activity of Isavuconazole and Other Azoles against Candida Clinical Isolates and Yeast Model Systems with Known Azole Resistance Mechanisms.

Sanglard D, Coste AT.

Antimicrob Agents Chemother. 2015 Oct 19;60(1):229-38. doi: 10.1128/AAC.02157-15. Print 2016 Jan.

33.

Acquired Multidrug Antifungal Resistance in Candida lusitaniae during Therapy.

Asner SA, Giulieri S, Diezi M, Marchetti O, Sanglard D.

Antimicrob Agents Chemother. 2015 Dec;59(12):7715-22. doi: 10.1128/AAC.02204-15. Epub 2015 Oct 5.

34.

RNA Enrichment Method for Quantitative Transcriptional Analysis of Pathogens In Vivo Applied to the Fungus Candida albicans.

Amorim-Vaz S, Tran Vdu T, Pradervand S, Pagni M, Coste AT, Sanglard D.

MBio. 2015 Sep 22;6(5):e00942-15. doi: 10.1128/mBio.00942-15.

35.

Adaptation of a Gaussia princeps Luciferase reporter system in Candida albicans for in vivo detection in the Galleria mellonella infection model.

Delarze E, Ischer F, Sanglard D, Coste AT.

Virulence. 2015;6(7):684-93. doi: 10.1080/21505594.2015.1081330.

36.

Stepwise emergence of azole, echinocandin and amphotericin B multidrug resistance in vivo in Candida albicans orchestrated by multiple genetic alterations.

Jensen RH, Astvad KM, Silva LV, Sanglard D, Jørgensen R, Nielsen KF, Mathiasen EG, Doroudian G, Perlin DS, Arendrup MC.

J Antimicrob Chemother. 2015 Sep;70(9):2551-5. doi: 10.1093/jac/dkv140. Epub 2015 May 27.

37.

Examining the virulence of Candida albicans transcription factor mutants using Galleria mellonella and mouse infection models.

Amorim-Vaz S, Delarze E, Ischer F, Sanglard D, Coste AT.

Front Microbiol. 2015 May 5;6:367. doi: 10.3389/fmicb.2015.00367. eCollection 2015.

38.

Tipping the balance both ways: drug resistance and virulence in Candida glabrata.

Vale-Silva LA, Sanglard D.

FEMS Yeast Res. 2015 Jun;15(4):fov025. doi: 10.1093/femsyr/fov025. Epub 2015 May 15. Review.

PMID:
25979690
39.

Mechanisms of Antifungal Drug Resistance.

Cowen LE, Sanglard D, Howard SJ, Rogers PD, Perlin DS.

Cold Spring Harb Perspect Med. 2014 Nov 10;5(7):a019752. doi: 10.1101/cshperspect.a019752. Review.

40.

Molecular mechanisms of action of herbal antifungal alkaloid berberine, in Candida albicans.

Dhamgaye S, Devaux F, Vandeputte P, Khandelwal NK, Sanglard D, Mukhopadhyay G, Prasad R.

PLoS One. 2014 Aug 8;9(8):e104554. doi: 10.1371/journal.pone.0104554. eCollection 2014.

41.

Resistance of Candida spp. to antifungal drugs in the ICU: where are we now?

Maubon D, Garnaud C, Calandra T, Sanglard D, Cornet M.

Intensive Care Med. 2014 Sep;40(9):1241-55. doi: 10.1007/s00134-014-3404-7. Epub 2014 Aug 5. Review.

PMID:
25091787
42.

Pivotal role for a tail subunit of the RNA polymerase II mediator complex CgMed2 in azole tolerance and adherence in Candida glabrata.

Borah S, Shivarathri R, Srivastava VK, Ferrari S, Sanglard D, Kaur R.

Antimicrob Agents Chemother. 2014 Oct;58(10):5976-86. doi: 10.1128/AAC.02786-14. Epub 2014 Jul 28.

43.

Comprehensive approach for the detection of antifungal compounds using a susceptible strain of Candida albicans and confirmation of in vivo activity with the Galleria mellonella model.

Favre-Godal Q, Dorsaz S, Queiroz EF, Conan C, Marcourt L, Wardojo BP, Voinesco F, Buchwalder A, Gindro K, Sanglard D, Wolfender JL.

Phytochemistry. 2014 Sep;105:68-78. doi: 10.1016/j.phytochem.2014.06.004. Epub 2014 Jun 28.

PMID:
24984572
44.

Novel Macrocyclic Amidinoureas: Potent Non-Azole Antifungals Active against Wild-Type and Resistant Candida Species.

Sanguinetti M, Sanfilippo S, Castagnolo D, Sanglard D, Posteraro B, Donzellini G, Botta M.

ACS Med Chem Lett. 2013 Jul 22;4(9):852-7. doi: 10.1021/ml400187w. eCollection 2013 Sep 12.

45.

Novel role of a family of major facilitator transporters in biofilm development and virulence of Candida albicans.

Shah AH, Singh A, Dhamgaye S, Chauhan N, Vandeputte P, Suneetha KJ, Kaur R, Mukherjee PK, Chandra J, Ghannoum MA, Sanglard D, Goswami SK, Prasad R.

Biochem J. 2014 Jun 1;460(2):223-35. doi: 10.1042/BJ20140010.

PMID:
24621232
46.

Distinct roles of Candida albicans drug resistance transcription factors TAC1, MRR1, and UPC2 in virulence.

Lohberger A, Coste AT, Sanglard D.

Eukaryot Cell. 2014 Jan;13(1):127-42. doi: 10.1128/EC.00245-13. Epub 2013 Nov 15.

47.

Identification and antifungal susceptibility of a large collection of yeast strains isolated in Tunisian hospitals.

Eddouzi J, Lohberger A, Vogne C, Manai M, Sanglard D.

Med Mycol. 2013 Oct;51(7):737-46. doi: 10.3109/13693786.2013.800239. Epub 2013 Jun 14.

PMID:
23768242
48.

Molecular mechanisms of drug resistance in clinical Candida species isolated from Tunisian hospitals.

Eddouzi J, Parker JE, Vale-Silva LA, Coste A, Ischer F, Kelly S, Manai M, Sanglard D.

Antimicrob Agents Chemother. 2013 Jul;57(7):3182-93. doi: 10.1128/AAC.00555-13. Epub 2013 Apr 29.

49.

Gain-of-function mutations in PDR1, a regulator of antifungal drug resistance in Candida glabrata, control adherence to host cells.

Vale-Silva L, Ischer F, Leibundgut-Landmann S, Sanglard D.

Infect Immun. 2013 May;81(5):1709-20. doi: 10.1128/IAI.00074-13. Epub 2013 Mar 4.

50.

Fermentative 2-carbon metabolism produces carcinogenic levels of acetaldehyde in Candida albicans.

Marttila E, Bowyer P, Sanglard D, Uittamo J, Kaihovaara P, Salaspuro M, Richardson M, Rautemaa R.

Mol Oral Microbiol. 2013 Aug;28(4):281-91. doi: 10.1111/omi.12024. Epub 2013 Feb 28.

PMID:
23445445

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